E176 - Dr. Mindy Pelz: Why Midlife Feels So Disorienting (And What It’s Trying to Teach You)
E176 - Dr. Mindy Pelz: Why Midlife Feels So Disorienting (And What It’s Trying to Teach You)  
Podcast: Know Thyself
Published On: Tue Dec 16 2025
Description: Dr. Mindy Pelz returns to explore the deeper meaning of aging, menopause, and the profound psychological and neurological transformations women undergo as they grow older. Drawing from neuroscience, anthropology, mythology, and personal experience, Mindy reframes menopause not as a decline—but as an initiation into wisdom, sovereignty, and inner authority.We discuss the concept of the “second innocence,” the pruning and rewiring of the female brain across hormonal transitions, the grandmother hypothesis, and why modern culture fears aging women. Mindy shares how trauma, grief, solitude, and uncertainty can become gateways to resilience, neuroplasticity, and self-discovery—especially when women stop outsourcing their worth and begin listening inward.Boost your hydration with Pique Life Tea (20% off here):https://www.piquelife.com/knowthyselfAndrés Book Recs: https://www.knowthyselfpodcast.com/book-list___________00:00 Intro - Dr. Mindy Pelz03:39 The return to the second innocence08:18 What’s the purpose of menopause?16:09 Where the shift begins23:04 Supporting others without abandoning yourself31:57 Being considerate vs owning others’ emotions34:14 Ad: Pique Life35:55 The power of solitude43:26 Letting go52:48 From power over to power within56:48 The brain architecture of wisdom1:02:24 Transformation: From a caterpillar to a butterfly1:19:58 Fasting during menopause1:26:35 Knowing when and how to detox1:32:31 Healing through breathwork, EMDR, psilocybin1:45:12 Lacking a support system1:49:07 Closing thoughts___________Episode Resources: Her new book: https://bookshop.org/p/books/age-like-a-girl-why-the-brain-changes-that-happen-after-40-set-you-up-for-your-best-life-yet-dr-mindy-pelz/1d7c0fe95ab52c4f?ean=9781401975562&next=thttps://www.instagram.com/dr.mindypelzhttps://www.drmindypelz.com/https://www.instagram.com/andreduqum/https://www.instagram.com/knowthyself/https://www.youtube.com/@knowthyselfpodcasthttps://www.knowthyselfpodcast.com