#838: The Random Show — The 2–2–2 Rule, The Future of AI, Bioelectric Medicine, Surviving Modern Dating, The Promises of DORAs for Alzheimer’s, and Wisdom from Anthony de Mello
Podcast: The Tim Ferriss ShowPublished On: Wed Dec 03 2025
Description: Welcome to another wide-ranging "Random Show" episode that I recorded with my close friend Kevin Rose (digg.com)!This episode is brought to you by:Qlosi prescription eye drop used to treat age-related blurry near vision (presbyopia) in adults: https://Qlosi.com/TimDavid Protein Bars with 28g of protein, 150 calories, and 0g of sugar: https://davidprotein.com/Tim (Buy 4 cartons, get the 5th free.)Eight Sleep Pod Cover 5 sleeping solution for dynamic cooling and heating: EightSleep.com/Tim (use code TIM to get $400 off your very own Pod 5 Ultra)Coyote the card game, which I co-created with Exploding Kittens: https://coyotegame.comTimestamps:[00:00:00] Start.[00:00:52] Why Kevin concluded nearly seven months of sobriety, and the 2-2-2 Rule he now follows for alcohol consumption.[00:07:12] My recent adventures in accelerated TMS and bioelectric medicine.[00:21:09] The tragic death of Nolan Williams and funding future research through the Saisei Foundation.[00:24:23] Aphantasia vs. hyperphantasia, and Joshua Waitzkin's ability to "feel" chess.[00:33:12] DORAs for sleep and Alzheimer's prevention: Matt Walker, Belsomra, and the terrifying p-tau blood test.[00:41:21] Dale Bredesen's kitchen-sink approach to dementia and the ketogenic connection.[00:46:22] The rapid pace of AI development: Why your opinion from three months ago is already obsolete.[00:49:40] Google's full-stack advantage: TPUs, Gemini 3, and why they were built for this moment.[00:52:50] The future of venture capital: Seed rounds shift later as entrepreneurs gain leverage.[00:58:05] Kevin's three AI investment buckets: Power, data centers, and bloated companies ripe for automation.[01:02:05] Holiday gift ideas and recommended reading.[01:17:41] The Way App and meditation with Zen master Henry Shukman.[01:21:44] Kevin's AI stack: Nothing earbuds, Sandbar ring, Notion AI, and the NotebookLM podcast hack.[01:26:58] Oboe.fyi: The AI learning platform and my investment philosophy.[01:32:09] My new girlfriend, the perils of modern dating apps, and building a communication toolkit.[01:38:17] Terry Real's relationship wisdom: Why objective reality has no place in an argument.[01:47:18] Dog updates: Molly, a new puppy, and Toaster on rapamycin.[01:47:58] Parting thoughts and happy holidays.*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim’s email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim’s books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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