The Ketogenic Diet with Dr. Dominic D'Agostino
The Ketogenic Diet with Dr. Dominic D'Agostino  
Podcast: The Dr. Layne Norton Podcast
Published On: Mon Aug 17 2026
Description: In this episode of the Dr. Layne Norton Podcast, Layne sits down with renowned researcher and ketogenic diet expert Dr. Dominic D’Agostino to dive deep into the science of the ketogenic diet. Professor Dominic D’Agostino (University of South Florida Morsani College of Medicine / Institute for Human and Machine Cognition) is one of the leading voices on nutritional ketosis, exogenous ketones, and metabolic therapies. Together, they unpack what the research actually shows about keto – beyond the hype and social media claims.They cover the mechanisms of ketosis, potential therapeutic applications (including epilepsy, metabolic health, neurological conditions, and ongoing research areas like cancer support), practical considerations for implementing a well-designed ketogenic approach, common misconceptions, protein and micronutrient needs, exogenous ketones, and how keto stacks up for fat loss, performance, and long-term adherence compared to other dietary strategies. Expect an evidence-based, no-BS conversation that prioritizes data over dogma.#KetogenicDiet #Keto #DominicDAgostino #LayneNorton #NutritionScience #MetabolicHealth #EvidenceBasedNutrition #DrLayneNortonPodcastSPONSORS• David Protein - Buy 4 cartons, get 1 FREE at: https://davidprotein.com/pages/layne• REPS Research Review: https://biolayne.com/repsLAYNE'S COMPANIESCarbon Diet Coach: https://joincarbon.com/podcastOutwork Nutrition: https://outworknutrition.comREPS Research Review: https://biolayne.com/repsWorkout Builder: https://biolayne.com/workout-builderTeam Biolayne: https://biolayne.com/online-coachingPhysique Coaching Academy: https://physiquecoachingacademy.comFOLLOW LAYNEhttp://www.facebook.com/laynenortonhttp://www.twitter.com/biolaynehttp://www.instagram.com/biolayneTIMESTAMPS0:00:00 - Intro0:02:37 - Dom's Background0:05:57 - Ketones and Seizures0:15:23 - Animal Research0:18:42 - David Protein0:20:17 - Mechanisms of Ketone Therapy0:28:07 - Magnesium0:29:12 - Dementia/Alzheimers0:37:55 - Cancer0:45:38 - REPS Research Review0:46:29 - Cancer Cont.1:16:50 - Muscle Hypertrophy1:27:55 - Fasting1:38:33 - Training2:01:42 - Ranking Importance2:04:34 - Last Question2:20:13 - OutroSHOW NOTEShttps://biolayne.com/podcasts/dr-layne-norton-podcast/