GLP-1s and The Sympathetic Spiral of Doom: Stress, Mitochondria, and Health Optimization w/ Dr. Scott Sherr
Podcast: GLP-1 Hub: Support, Community, and Weight LossPublished On: Mon Mar 09 2026
Description: In this episode, Ana sits down with Dr. Scott Sherr to break down the “sympathetic spiral of doom” and how chronic stress can quietly drive fatigue, insulin resistance, poor recovery, and stalled progress — especially for people using GLP-1 medications.Dr. Sherr explains how sympathetic overdrive (fight-or-flight) and mitochondrial dysfunction can reinforce each other, why “wired but tired” is a major red flag, and how health optimization habits can help restore resilience. They also discuss practical ways to support better nervous-system balance, metabolic flexibility, sleep, and long-term outcomes beyond the scale.About Dr. Scott Sherr:Dr. Scott Sherr is a board-certified internal medicine physician specializing in Health Optimization Medicine (HOMe) and hyperbaric oxygen therapy (HBOT). He serves as COO of Troscriptions, and as VP of Health Optimization Medicine and Practice, the nonprofit arm that trains clinicians to focus on optimizing health rather than simply treating disease. He is also Chief Medical Officer of OneBase Health, developing integrated health technologies.Troscriptions: https://troscriptions.com/glp1hubInstagram: https://www.instagram.com/troscriptions/https://www.instagram.com/drscottsherr/https://www.instagram.com/onebasehealth/https://www.instagram.com/homehopeorg/Youtube: https://www.youtube.com/@troscriptionshttps://www.youtube.com/@drscottsherrLinked In: https://www.linkedin.com/in/drsherr/https://www.linkedin.com/company/troscriptions/https://www.linkedin.com/company/onebasehealth/This Episode is Sponsored By:I Can't Believe it's not Butter!: See how NutriRich “I can’t Believe it’s not Butter!” can help on your GLP-1 Journey at the ICBINB Wellness HubMetagenics: Explore our complete collection of science-backed supplements.Want to Learn More about GLP-1 Hub?Join the Steady State newsletter and get a FREE 7-day meal plan + weekly support and strategy to optimize your journey: http://join.glp-1hub.comJoin the membership:https://glp-1hub.com/membershipVisit our GLP-1 Hub store:https://shop.glp-1hub.comWant to connect more with GLP-1 Hub? Instagram: https://www.instagram.com/glp1hubTiktok: https://www.tiktok.com/@glp1hubYouTube: https://www.youtube.com/@glp-1hub*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.
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