Extend Podcast with Darshan Shah, MD
Extend Podcast with Darshan Shah, MD

Extend with Darshan Shah, MD is a podcast dedicated to cutting-edge science, research, tools, and protocols designed to help you extend your healthspan. Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board certified surgeon and accumulating over two decades of practice, I have discovered that a mere 20% of health knowledge yields 80% of the results. That's why this podcast is all about cutting through the noise on how to turn back the aging clock. I interview world-renowned medical practitioners, doctors, experts, and thought leaders, offering you a step-by-step guide and actionable advice to proactively avoid disease and optimize your health. Plus, I share weekly solo episodes giving you quick, digestible protocols for successfully extending your healthspan.

You can eat healthy, exercise daily, and still struggle with fatigue, inflammation, or brain fog. Why? Because every system in your body is connected. The gut, brain, and immune system are constantly communicating, and most health plans ignore that network. In this episode of Extend, I sit down with Dr. Karan Rajan to explore how the gut microbiome shapes everything from digestion and immunity to mood, skin, and longevity. We unpack the science behind leaky gut, fiber diversity, fermented foods, and the connection between microbiome imbalance and chronic inflammation. We also dive into practical steps such as how to feed all three layers of your colon, the right way to use fiber supplements, the truth about probiotics, and how daily habits like sleep timing, stress, and even phone use in the bathroom affect gut health. Dr. Karan Rajan is a surgeon, educator, and gut health expert with more than five million followers across social media. His research in microbiome science and human health has made him one of the most trusted voices translating complex medicine into actionable steps for modern life. What's Discussed: (00:00) From Surgery to the Science of the Microbiome (05:18) How Fiber Diversity Fuels a Healthy Gut (12:14) The Link Between Leaky Gut, Skin, and Inflammation (19:49) What Destroys the Microbiome and How to Rebuild It (27:56) Poop, Circadian Rhythms, and Real Gut Health Markers (40:13) Fiber Supplements, Fermented Foods, and Smart Probiotics (54:05) Inside the Future of Gut Health and the Loam Project   Thank You to Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 10% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Pendulum: Go to pendulumlife.com and use code EXTEND at checkout for 20% off all Pendulum membership first orders.   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram:@darshanshahmd   Learn more about Dr. Karan Rajan: Instagram: drkaranrajan  YouTube: Dr Karan  Linkedin: Dr Karan Rajan
What if the future of medicine isn't about diagnosing disease, but preventing it entirely? For decades, our healthcare system has only reacted once things go wrong. We measure when there are symptoms. We intervene when there is a crisis. But what if we could see the shift before it becomes an illness? In this episode of EXTEND, I'm joined by Josh Clemente, founder of Levels and former SpaceX engineer, to explore how continuous health monitoring is about to change human health at scale. Josh shares how engineering principles—not traditional medicine—first revealed the hidden metabolic patterns that were draining his energy, affecting his cognition, and pushing him toward disease long before any lab test reflected it. We discuss why continuous glucose monitoring is only the first step in this revolution, how data empowers individuals instead of the healthcare system, and why the next era of health will be defined by observability—real-time insight that lets you adjust, course-correct, and optimize your biology every single day. Josh Clemente is the co-founder of Levels, a metabolic health platform bringing continuous glucose monitoring and real-time lifestyle coaching to the mainstream. Previously, he led life support systems engineering at SpaceX, where he developed safety technology for astronauts aboard the Crew Dragon spacecraft. What's Discussed: (00:00) Why You Should Own Your Health Data — Not Your Doctor (05:50) The Tech That's About to Replace Annual Checkups (17:47) The Medical System Won't Fix Chronic Disease — You Will (26:02) AI + Biology: The Turning Point We've Been Waiting For (35:15) Learning to "Read" Your Body in Real Time (45:54) How Small Daily Inputs Create (or Reverse) Disease (57:05) What's Coming Next in Wearable Health Tech (01:06:57) Continuous Monitoring: The Future of Metabolic Health (01:13:57) Metabolic Health = Energy. And Energy = Life. (01:27:11) Final Takeaways: Empowerment, Data, and Ownership Thank You for Our Sponsors:  NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram:@darshanshahmd   Learn more about Josh Clemente:  Instagram: @levels Instagram: @josh.f.clemente  Website: https://www.levels.com/
What if the real key to longevity has nothing to do with your workouts or supplements, but with how well your brain is wired to adapt, repair, and thrive? In this episode of EXTEND, I sit down with Dr. Amir Vookshoor, a board-certified neurosurgeon and founder of NeuroVella Brain Spa, to explore how modern neuroscience and biohacking are merging to shape the future of brain health. We dive into how trauma, inflammation, and stress rewire the nervous system and how to reset it. From neurofeedback and TMS to breathwork, sleep, and emerging tools like plasmapheresis and light-based neuromodulation, this conversation reveals the most powerful, science-backed ways to reprogram the brain for focus, resilience, and longevity. Dr. Amir Vookshoor is a pioneering neurosurgeon integrating modern neuroscience with holistic medicine to help patients achieve optimal brain function. His work bridges surgery, neuroplasticity, and mind-body science to unlock new pathways for healing and human potential. What's Discussed: (00:00) From Neurosurgery to the Future of Brain Health (10:42) How Stress and Trauma Rewire the Nervous System (19:58) Neurofeedback, Brain States, and Consciousness (31:25) Advanced Imaging and Early Alzheimer's Prevention (40:16) Plasmapheresis and the Science of Brain Renewal (50:27) Breathwork, Sleep, and the Brain-Body Connection   Thank You for Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 10% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram:@darshanshahmd   Learn more about : Instagram: @drvokshoor Website:  NEUROSURGERY & SPINE GROUP
What if the key to living longer and feeling younger has been hidden in ancient medicine all along? Long before supplements, peptides, or wearables, healing was about restoring balance through food, movement, belief, and nature. Today, those same principles are being shown by modern science to protect your cells, extend your healthspan, and reverse root causes of disease. In this episode of EXTEND, I'm joined by Dr. Josh Axe and we explore how ancient healing systems like Ayurveda and Traditional Chinese Medicine intersect with today's most advanced longevity research. We dive into the biology of faith and mindset, how chronic stress and emotion impact gene expression, and the connection between gut health, inflammation, and aging. We also discuss how to bridge natural and modern medicine, the surprising role of peptides and stem cells in regeneration, and why true longevity begins with the everyday habits you practice, not just the protocols you chase. Dr. Josh Axe, DC, DNM, CNS, is a doctor of chiropractic and natural medicine, a clinical nutritionist, and the co-founder of Ancient Nutrition. He is also the host of the podcast The Dr. Josh Axe Show and the bestselling author of Ancient Remedies and The Biblical Diet. We Also Discuss: (00:04) Traditional vs. Western medicine and where real healing happens (08:51) Ancient nutrition and the science of longevity (14:31) The emotional biology of healing in Eastern medicine (25:55) Biblical health codes and the roots of longevity (38:06) Mold toxicity, early signs, triggers, and recovery (52:26) Illness, purpose, and the path to healing (01:12:38) Regenerative therapies using peptides and stem cells (01:27:59) The future of wellness through ancient wisdom and modern science Thank You to Our Sponsors: Timeline: Go to timeline.com/drshah to get 20% off your order. Function Health: Learn more and join using functionhealth.com/drshah. The first 1000 get a $100 credit toward their membership. Visit www.functionhealth.com/drshah or use gift code DRSHAH100 at sign-up to own your health.  Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram:@darshanshahmd   Learn more about Dr. Josh Axe: Website: www.draxe.com Instagram:@drjoshaxe YouTube: www.youtube.com/@DrJoshAxe
What if the real secret to longevity isn't found in science alone, but in how we choose to live, love, and connect every day? In this special posthumous episode of EXTEND, I revisit one of the most meaningful conversations I've ever had — with Dr. Gladys McGarey, the 103-year-old physician known as the Mother of Holistic Medicine and author of The Well-Lived Life. Before her passing, Dr. McGarey shared a century's worth of wisdom on what truly heals us, from the inside out. We talk about how she helped create the holistic medicine movement, the deeper meaning behind her "Five L's" — love, life, laughter, labor, and listening — and how energy, purpose, and community shape both health and happiness. She also shares powerful stories from her early life in India, her encounter with Gandhi, and how compassion became the foundation of her medical practice. Dr. Gladys McGarey reminds us that medicine isn't just about curing disease — it's about nurturing the human spirit, and remembering that love itself is one of the most powerful healing forces we have.   We Also Discuss: (00:00) A Century of Healing: The Life and Legacy of Dr. Gladys McGarey (09:45) Growing Up in India and Meeting Gandhi (20:23) How Holistic Medicine Was Born, and Why It Still Matters (25:32) The Physician Within: What True Healing Really Means (27:20) Energy, Purpose, and the Secret to Staying "Alive" at Any Age (33:55) Turning Setbacks into Teachers: Finding Growth in Pain (37:46) Why Community Is the Medicine We're Missing (43:54) The Vision for a Healing Village, Where Love and Life Lead Medicine Thank You to Our Sponsor: IM8: Try IM8 today with a 30-day money back guarantee. You can get 10% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Learn more about Dr. Shah:  Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram:@darshanshahmd   Learn more about Dr. Gladys McGarey: Website:https://gladysmcgarey.com/Instagram: @livingmedicinedr
What if the real turning point for women's health isn't menopause itself, but the decade before it?  Long before the symptoms hit, your brain, bones, and heart are already changing, silently. You can train hard, eat clean, and still lose strength, bone density, and cognitive sharpness if you're not addressing the biology underneath it all. In this episode of EXTEND, I'm joined by Dr. Vonda Wright, orthopedic surgeon, researcher, and author of Unbreakable, to talk about how women can take control of midlife long before the "change." We get into what actually happens when estradiol starts to fall, why bone is an active endocrine organ (not just structure), and how to measure what really predicts longevity: VO₂ max, grip strength, sit-to-stand, and bone quality. We also discuss her FACE framework, flexibility, aerobic base, carrying load, and equilibrium, a smarter way to train for longevity that protects your brain, bones, and hormones.  Dr. Vonda Wright is a double board-certified orthopedic surgeon, researcher, and author of Unbreakable. She's a leading expert in active aging and musculoskeletal longevity, known for helping midlife women build strength, preserve bone health, and optimize performance through data-driven prevention.  What's Discussed: (00:00) Why Women Need to Rethink Midlife Health (05:54) The Longevity Equation: Strength, Hormones, and Prevention (17:39) The Forgotten Organ Driving Women's Aging: Bone\ (28:44) How to Build Bone Quality (Not Just Density) (34:55) Training Smarter in Midlife: The FACE Protocol for Strength and Power (44:45) How to Find Real Fitness Inspiration Online, and Filter Out the Noise Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram:@darshanshahmd   Learn more about Dr. Vonda Wright:  Website: https://www.drvondawright.com/ Instagram: https://www.instagram.com/drvondawright
You can eat clean, track your labs, take supplements, and still feel anxious, inflamed, tired, or flat. Why? Because the gut, brain, immune system, and hormones are in constant conversation, and most of us are only treating one side of that story. In this episode of Extend, I sit down with Dr. Will Cole to uncover the science behind the gut-brain axis, and why nervous system dysregulation might be the reason your biomarkers won't budge. We unpack how microbiome imbalances, silent inflammation, low vagal tone, and stored trauma show up as anxiety, constipation, brain fog, and burnout… even when you're "doing everything right." We also get practical: testing beyond standard blood work, HRV as a window into resilience, breathwork vs. meditation, EMDR, "ugly journaling," and when devices like Apollo Neuro and Sensate actually help. Dr. Will Cole is a leading functional medicine expert, a pioneer in gut-brain health, neuroimmune disorders, and autoimmune healing. He is also the host of the top-ranked podcast The Art of Being Well and the New York Times bestselling author of books including Gut Feelings, The Inflammation Spectrum, and Ketotarian. What's Discussed: (00:00) From Functional Medicine to the Gut-Brain Revolution (13:14) How Trauma, Serotonin, and the Vagus Nerve Shape the Mind-Gut Connection (21:13) Healing the Nervous System: Journaling, EMDR, and Wearable Vagus Nerve Tech (30:15) Why Real Health Change Starts with Individuals, Not Institutions (35:07) Food Deserts, Misinformation, and Taking Your Health Back (43:04) Regenerative Supplements, Soil Health & The Future of Functional Medicine   Thank You for Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 10% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram:@darshanshahmd   Learn more about Dr. Will Cole: Instagram: @drwillcole Instagram: @theartofbeingwell_  Youtube: @DrWillCole
You have brain fog. You're gaining weight faster and losing it slower. You think it's stress, aging, or just life… But what if it's your liver screaming for help? In this episode of Extend, I'm joined by Siggi Clavien, liver health expert and founder of The Liver Clinic, to uncover the silent epidemic destroying our health from the inside out. We explore why 70% of liver disease today has nothing to do with alcohol, the actual damage done by Tylenol, and why your "normal" blood work might be hiding liver damage. We also dive into technology that can detect damage years before blood tests, and what might be your key to reversing chronic disease. Siggi Clavien is a liver health specialist with 28 years in phytomedicine development and founder of The Liver Clinic. He combines ancient Eastern medicine wisdom with modern technology to help people detect and reverse liver damage. We Also Discuss: (00:00) Health and Liver Function Discussion (07:12) Toxins, Diet, and Fatty Liver Impact (17:13) Liver Damage Detection and Management (28:27) Toxic Exposure and Health Protection (37:28) Liver Health and Protection Strategies (45:17) Understanding Liver Scan Technology and Risks (56:20) Diet, Exercise, and Liver Health (01:00:56) Detoxification, Liver Health, and Deliverance (01:10:39) Liver Health Tracking and Advancements (01:16:36) Health Care Access and Support Thank you to our Sponsors: Timeline: Go to timeline.com/drshah to get 20% off your order.   Learn more about Dr. Shah: Website: https://www.drshah.com/  Clinic: https://www.next-health.com/ Instagram: @darshanshahmd   Learn more about Siggi Clavien: Website: https://us.loveyourliver.com/ https://theliverclinic.com/  Instagram: @deliverance.elixir @siggiclavien
We track our sleep, count our macros, optimize every supplement, yet most people's bodies are still stuck in survival mode. What if true longevity starts not with another biohack, but with safety? When your nervous system feels safe, inflammation drops, digestion normalizes, and recovery accelerates.  In this episode of Extend, I sit down with Gabby Bernstein, #1 New York Times bestselling author and host of the Dear Gabby podcast, to explore how emotional regulation, breathwork, and Internal Family Systems (IFS) therapy rewire the nervous system for resilience. Together, we break down how HRV reflects longevity, why "soft" tools like breath and meditation have hard science behind them, and how pairing spiritual practice with functional medicine creates lasting health transformation. Gabby Bernstein is a #1 New York Times bestselling author, host of the Dear Gabby podcast, and a leading teacher in self-help and spiritual development. For 20 years she's democratized tools like meditation, trauma-informed healing, and IFS for everyday life. In this episode, she shows us how to make emotional safety a daily practice, and why that might be the most powerful longevity intervention we have. What's Discussed: (00:00) From Burnout to Breakthrough: A Spiritual Path to Sobriety (03:39) What Safety Really Feels Like, and How to Create It (12:14) Turning Pain Into Peace: Healing Trauma Through Spiritual Practice (18:20) Meeting Your Protector Parts Instead of Fighting Them (30:42) Radical Self-Compassion as the Fastest Way to Heal (33:59) How to Reprogram Your Inner Protectors for Real Wellness (46:30) When Doctors Need Healing Too: Trauma Inside Medicine (51:22) Where Science Meets Spirit: The Biology of Belief (57:55) Faith, Energy, and the New Language of Healing (01:08:44) Manifestation as Medicine: How Your Mind Shapes Biology (01:14:49) The App That's Redefining Daily Spiritual Practice Thank You to Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 10% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Function Health: Learn more and join using functionhealth.com/drshah . The first 1000 get a $100 credit toward their membership. Visit www.functionhealth.com/drshah or use gift code DRSHAH100 at sign-up to own your health.   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram:@darshanshahmd   Learn more about Gabby Bernstein: Instagram: @gabbybernstein Website: https://gabbybernstein.com/ Book: 7 Habits of a Super Attractor: Effortlessly Attract Your Desires
What if your immune system could actually age backwards? For decades, we've accepted that inflammation, fatigue, and slower recovery are inevitable with age, but new research proves otherwise. Your immune system isn't doomed to decline; it can be retrained to act younger, stronger, and more resilient. In this episode of Extend, I sit down with Dr. Jeffrey Bland, the father of functional medicine, to explore the groundbreaking science of immune rejuvenation. We break down how chronic inflammation accelerates aging, why gut health holds the key to immune balance, and the nutrients that can literally reprogram gene expression. We also discuss how a 90-day nutrition protocol led to a 47% reduction in immune aging, and what that means for your longevity. Dr. Jeffrey Bland is widely recognized as the father of functional medicine, a thought leader who's spent over 40 years redefining how we understand health and disease. He's the founder of the Institute for Functional Medicine and Big Bold Health, where he's pioneering new research on immune rejuvenation and personalized nutrition.   We Also Discuss: (00:00) The birth of functional medicine and how it reshaped modern healthcare (08:45) Why traditional medicine overlooks the body's interconnected systems (18:22) How your immune system drives aging, resilience, and recovery (28:09) The gut-immunity connection and why inflammation accelerates aging (38:40) The science behind reversing immune aging and restoring balance (49:33) How diet and polyphenols influence immune gene expression (01:00:18) The epigenetic switch that controls healthy aging (01:11:42) Data, biomarkers, and the rise of personalized health (01:25:30) The future of collective health and community immunity (01:36:39) How to apply immune rejuvenation principles in your daily life Thank You for Our Sponsors: Pendulum: Use code DARSHAN or use the link https://pendulumlife.com/discount/DARSHAN to get 20% off Pendulum membership first orders.   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram:@darshanshahmd   Learn more about Dr. Jeff Bland: Instagram: @drjeffreyblandBig Bold Health: @bigboldhealth Website: https://bigboldhealth.com/
What if your brain's biggest limitation isn't its capacity, but your failure to train it? In this episode of Extend, Maya Raichoora joins me to share how visualization techniques helped her reverse debilitating ulcerative colitis.  We explore the neuroscience behind visualization, from rewiring neural pathways to regulating the immune system through thought. We dive into five distinct types of visualization and why mental fitness deserves the same daily dedication as physical fitness. Maya Raichoora is the UK's leading mental fitness and visualization expert, bestselling author of "Visualize," and a former international badminton player. After being told she'd need lifelong immunosuppressive medication or colon removal surgery for ulcerative colitis at age 17, Maya used visualization and mental training to achieve complete symptom remission. She now coaches elite athletes, C-suite executives, and teaches the science of training the brain. We Also Discuss: 01:45 - How Visualization Reversed Severe Ulcerative Colitis Without Surgery 03:45 - The "Piranha Technique": Making Pain Playful Through Creative Imagery 11:48 - The Brain-Gut Connection: Why Your Colon Has as Many Neurons as Your Brain 18:06 - How Your Brain Directly Controls Immune Cell Production 21:15 - The Five Types of Visualization 26:07 - Why Your Brain's Stories Become Your Ceiling 29:55 - The Neuroscience of Mental Rehearsal: Why Imagined Reps Equal Real Ones 38:00 - The 90-Second Rule for Releasing Trapped Emotions 55:32 - The Language of Medicine: How "Incurable" Becomes a Self-Fulfilling Prophecy 1:04:15 - Mirror Neurons: Why You Become What You Watch   Thank You for Our Sponsors: Try IM8 today with a 30-day money back guarantee. You can get 10% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ https://www.instagram.com/nexthealth/  Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Maya Raichoora: LinkedIn: https://www.linkedin.com/in/maya-raichoora/  Website: https://mayaraichoora.com/
What if the biggest threat to your brain health isn't genetics, but the environment you're living in? In this episode of Extend, Max Lugavere joins me to share how environmental toxins, metabolic dysfunction, and dietary choices are driving the explosion of neurodegenerative diseases. We dive into why Alzheimer's begins 30-40 years before diagnosis, and the specific lifestyle interventions that can dramatically reduce your risk. From the dangers of golf course proximity to the surprising role of mouthwash in hypertension, this conversation challenges everything you thought you knew about protecting your brain. Max Lugavere is a health and science journalist, filmmaker, and bestselling author of "Genius Foods" and "The Genius Life." His documentary "Little Empty Boxes" chronicles his mother's battle with Lewy body dementia and explores the preventable nature of cognitive decline. Max has become one of the leading voices in brain health optimization. We Also Discuss: 08:02 - Why Neurodegenerative Diseases Begin 30 Years Before Symptoms 12:53 - Different Types of Dementia and Movement Disorders Explained 14:24 - Environmental Toxins Linked to Parkinson's Disease 16:03 - How Living Near Golf Courses Doubles Parkinson's Risk 31:04 - How One Gram of Pancreatic Fat Loss Restores Insulin Sensitivity 35:21 - Fasting Insulin: The Biomarker That Predicts Alzheimer's Early 37:12 - The Role of Ketogenic Diets in Brain Energy Metabolism 51:19 - How 20 Grams of Creatine Improved Cognition in Alzheimer's Patients 57:38 - The Truth About Seed Oils vs. Extra Virgin Olive Oil 1:09:04 - Omega-3s and the 50% Alzheimer's Risk Reduction 1:13:23 - Why Antiseptic Mouthwash May Raise Blood Pressure   Thank You for Our Sponsors: Timeline: Go to timeline.com/drshah to get 20% off your order. Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ https://www.instagram.com/nexthealth/  Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Max Lugavere: Instagram: @maxlugavere Website: https://www.maxlugavere.com/
Did you know, 80% of perimenopause symptoms are brain-related, but it takes 4-6 doctor visits to get a diagnosis? In this episode of Extend, Dr. Mariza Snyder reveals why perimenopause has been medicine's best-kept secret and how women can reclaim their health during this critical transition. We discuss why perimenopause is called "the silent shift," the protective power of hormone replacement therapy, and why suffering through this transition is completely optional. Dr. Mariza also shares her personal hormone protocol and why she believes women deserve the gold standard of care during this pivotal decade. Dr. Mariza Snyder is a hormone and metabolic health expert specializing in perimenopause and menopause care. She's the author of "The Perimenopause Revolution" and host of the "Energized with Dr. Mariza" podcast. With nearly 15 years of experience helping women navigate hormonal transitions, she advocates for preventative hormone replacement therapy and comprehensive biomarker tracking. We Also Discuss: 04:54 - Why 80% of Perimenopause Symptoms Are Brain-Related 07:49 - The "Silent Shift" That Happens Years Before Missing Periods 11:21 - Why Standard Blood Work Keeps Women Suffering in Silence 12:57 - The Biomarkers Every Woman Should Track Starting at 35 30:49 - What Women Can Do to Start Managing Perimenopause 39:45 - How Hormone Replacement Therapy Acts as Your "Protective Shield" 55:21 - The Truth About Breast Cancer Risk and HRT 1:01:21 - Advanced Cancer Screening Strategies for Women 1:05:24 - Why Sleep Consistency Can Change Your Life in 10 Days 1:06:23 - The Mindset Shifts That Make Perimenopause Empowering   Thank You for Our Sponsors: NextHealth: Your destination for cutting-edge health optimization from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ https://www.instagram.com/nexthealth/  Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Mariza Snyder: Instagram: https://www.instagram.com/drmariza/  Website: https://drmariza.com/
What does it take to translate athletic excellence into mastery of life, relationships, and business? In this episode of Extend, legendary big wave surfer Laird Hamilton and pro volleyball champion Gabby Reece join me to share the mindsets and practices that have sustained their 30-year relationship and individual success. We discuss why "getting tired" is essential for health and how they've built a thriving business around authentic products. We also discuss the simple daily rituals that matter more than complex optimization protocols. Laird Hamilton is a pioneer of big wave surfing and hydrofoiling, while Gabby Reece dominated professional volleyball before becoming a wellness advocate. Together, they created XPT (Extreme Performance Training) and co-founded Laird Superfood, a publicly-traded company focused on functional nutrition. We Also Discuss: Why "Getting Tired" Makes Food Taste Better and Improves Sleep Quality The Art of Comfortable Confrontation in Marriage and Business Why Observing Nature Is Medicine for Modern Stress The Decision Fatigue Trap That's Sabotaging Your Day Before 9 AM Why They Choose Their Suffering Instead of Letting Life Choose for Them Thank You for Our Sponsors: Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ @nexthealth  Instagram: @darshanshahmd   Learn more about Gabby Reece and Laird Hamilton: Instagram: @airdhamilton @gabbyreece
What happens when a traditional doctor discovers that everything they were taught in medical school is keeping patients sick? In this episode of Extend, Dr. Jess Peatross joins me to discuss the hidden toxins that could be behind your symptoms. We discuss why 95% of people don't get enough fiber, the "kill-bind-sweat" protocol that's gone viral for detoxification, and why your "normal" blood work might be missing the real problem. Dr. Jess also shares her shocking experience losing her medical license for questioning vaccine protocols. Dr. Jess Peatross is a traditionally trained internal medicine physician who worked as a hospitalist for seven years before transitioning to functional medicine. She's the founder of Wellness Plus, an online platform helping people detox safely from environmental toxins, and Aegis Formulas supplement company. She specializes in treating complex chronic conditions involving mold toxicity, parasites, heavy metals, and environmental toxin exposure. We Also Discuss: Why Traditional Blood Work Misses 95% of Chronic Disease Causes How the "Kill-Bind-Sweat" Protocol Detoxes Your Body Safely The Vibrant Total Tox Test That Reveals Hidden Environmental Toxins Why Parasites Are More Common in America Than You Think How Modern Energy-Efficient Homes Create Perfect Mold Conditions The MTHFR and COMT Genes That Determine Your Detox Ability Why 95% of People Are Fiber-Deficient and How It Drives Disease The Microscope Method vs. Modern Parasite Testing Limitations How to Test Your Home Environment for Hidden Toxin Exposure Why You Must Fix Your Nervous System Before Any Detox Protocol   Thank You for Our Sponsors: NextHealth: Your destination for cutting-edge health optimization from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ @nexthealth  Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Jess Peatross: Instagram: @dr.jess.md  Website: https://drjessmd.com/
What happens when a medical student gets diagnosed with stage 4 cancer and given three months to live? In this episode of Extend, Dr. Dawn Mussallem joins me to share her incredible journey from near-death to becoming a leading integrative oncologist at Mayo Clinic, proving that lifestyle interventions can dramatically improve cancer outcomes. We discuss how 42% of cancers are preventable through lifestyle changes, why ultra-processed foods increase cancer risk by 16%, and the shocking truth about soy and breast cancer. We also share her evidence-based protocol combining conventional treatments with integrative modalities. Dr. Dawn Mussallem is a double board-certified physician in Internal Medicine and Lifestyle Medicine at Mayo Clinic, where she designed the integrative breast oncology program. A cancer survivor who received a heart transplant in 2021, she combines personal experience with rigorous science to help patients optimize their health during and after cancer treatment. We Also Discuss: Why 75% of Cancers Are Caused by Lifestyle Factors (Not Genetics) How Ultra-Processed Foods Increase Cancer Death Risk by 30% The Shocking Truth About Soy and Breast Cancer (It's Actually Protective) Why Half Your Plate Should Be Vegetables or Fruits at Every Meal The 30 Diverse Plant Foods Per Week Rule for Optimal Gut Health Low-Dose Naltrexone's Immune-Boosting Effects for Cancer Patients Why Exercise During Chemotherapy Actually Improves Outcomes How Fermented Foods Support Cancer Prevention and Treatment The Mayo Clinic Protocol for Maintaining Vitality During Treatment Why Skipping Breakfast Increases All-Cause Mortality Risk   Thank You for Our Sponsors: Try IM8 today with a 30-day money back guarantee. You can get 10% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ https://www.instagram.com/nexthealth/  Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Dawn Mussallem: Instagram: https://www.instagram.com/drdawnmussallem/?hl=en  LinkedIn:  linkedin.com/in/dawn-mussallem-do-dipablm-2b360b57
What happens when elite fitness doesn't equal health? In this episode of Extend, Ben Greenfield joins me to discuss how blood tests showed he was metabolically compromised despite being an Ironman competitor, and shares the comprehensive testing protocols that changed his approach to wellness. We discuss the critical difference between fitness and health, Ben's biomarker testing strategy using wearables and lab work, and why he embraces hormesis - the concept that controlled stressors like heat, cold, and plant compounds build resilience. We also dive into why dietary diversity beats restrictive elimination diets and the importance of cycling supplements rather than continuous use. Ben Greenfield is a biohacker, bestselling author of "Boundless," podcast host, and founder of Kion supplements. A former professional athlete turned health optimization expert, he now coaches high-achievers on personalized health protocols. We Also Discuss: Why Fitness and Health Are Not the Same Thing (Despite What Most Athletes Think) The FASTER Study That Proved Fat Adaptation Could Rewrite Exercise Physiology The Complete Testing Protocol: Wearables, Blood Panels, and Genetic Analysis Why Heart Rate Variability Is Your Best Daily Stress Indicator The Problem With Continuous Supplement Use vs. Strategic Cycling How Microplastics Are Destroying Our Bodies (And What Actually Works to Remove Them) The Truth About Alcohol as a Hormetic Stressor in Small Doses How to Use CGMs Beyond Just Glucose Monitoring Why Most Gut Microbiome Tests Give Useless Food Recommendations Thank You for Our Sponsors: Function Health: Learn more and join using functionhealth.com/drshah. The first 1000 get a $100 credit toward their membership. Visit www.functionhealth.com/drshahn or use gift code DRSHAH100 at sign-up to own your health.  Timeline: 20% off your order. Go to timeline.com/drshah  Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ https://www.instagram.com/nexthealth/  Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Ben Greenfield: Instagram: https://www.instagram.com/bengreenfieldfitness/  Website:  https://boundlessbook.com/
What if everything you've been told about longevity supplements is based on hype rather than science? Dr. Eric Verdin, CEO of the Buck Institute for Research on Aging, joins me on the Extend podcast to separate fact from fiction in the longevity field.  We explore epigenetic reprogramming, why the immune system controls aging, and the reality that no supplements are proven to extend human lifespan. We also discuss how most people could live to 95 in good health using lifestyle interventions we already know work. Dr. Eric Verdin is the CEO and President of the Buck Institute for Research on Aging, the world's first independent research institute focused solely on aging. He has published over 200 peer-reviewed papers and is internationally recognized for his research on immune system aging and epigenetic regulation. We Also Discuss: Why There Are No Proven Anti-Aging Supplements or Drugs for Humans Yet How Yamanaka Factors Can Reverse Aging by Reprogramming Cells Back to Youth The Discovery That Immune System Aging Controls Whole-Body Aging Why Your Blood Contains 600 Different Cell Types (Not the 12 You Learned About) How Lifestyle Factors Could Add 30 Years of Healthy Life for Most People The Problem With "Instagram Medicine" and Unproven NAD Infusions Why Brian Johnson's Self-Experimentation Matters Despite the Controversy The Coming Revolution in Precision Medicine and Digital Twins How Organ-Specific Aging Clocks Predict Your Individual Disease Risk Why the Brain and Immune System Are the Two Most Important Aging Targets Thank You for Our Sponsors: Try IM8 today with a 30-day money back guarantee. You can get 10% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH    Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Eric Verdin: Instagram: https://www.instagram.com/ericverdin.buck/?hl=en  Website: https://www.buckinstitute.org/
What if the blood tests you're not getting are more important than the ones you are? In this episode of Extend, Dr. Jeremy London joins me to explore the three lifestyle modifications that prevent most cardiac disease.  We dive into how a continuous glucose monitor revealed his own pre-diabetes despite feeling perfectly healthy. We also share the blood tests your doctor isn't ordering, why vaping may be more dangerous than cigarettes, and how functional medicine filled the gap that traditional surgery couldn't address. Dr. Jeremy London is a board-certified cardiovascular surgeon with over 25 years of clinical experience. He received his medical degree from the Medical College of Georgia and completed his general surgery residency at St. Joseph's Hospital in Denver, Colorado, followed by a vascular and thoracic surgical fellowship at Carolinas Medical Center. Dr. London's mission is to provide accessible health information through his newsletter, podcast, and social platforms.  We Also Discuss: Why Vaping Is More Dangerous Than Cigarettes According to This Heart Surgeon The Three Blood Tests Your Doctor Isn't Ordering   How a Continuous Glucose Monitor Revealed Pre-Diabetes in a "Healthy" Surgeon Why 50% of Americans Have High Blood Pressure and Most Don't Know It The Calcium Score CT Scan That Reveals Hidden Heart Disease Risk Why VO2 Max Is the Most Powerful Predictor of Longevity How Functional Medicine Saved This Surgeon from Career Burnout The Walking Desk Hack That Gets 10,000 Steps During Work Hours Thank You for Our Sponsors: Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Timeline: Claim 10% off your first order now at https://www.timeline.com/partners/darshan-shah    Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Jeremy London: Instagram: https://www.instagram.com/drjeremylondon /  Website: https://www.drjeremylondon.com/
After spending years at a monastery, meditation expert Scott Schwenk discovered the way most people approach meditation is exactly what keeps them from succeeding. The myths around emptying your mind, sitting in painful positions, and chasing mystical experiences sabotage practice before it begins. In this episode of Extend, Scott and I discuss the 4-lens framework that transforms meditation from mystical pursuit to practical life skill. We explore his signature 6-point body softening technique that works in 30 seconds, why he stopped teaching fire breathing after becoming trauma-informed, and how to build a sustainable practice that integrates into real-world challenges. Scott Schwenk is a meditation teacher, breathwork facilitator, and consciousness coach who has spent decades studying both Eastern spiritual traditions and Western psychological approaches. He lived at a monastery, teaches internationally, and helps individuals and businesses integrate contemplative practices into daily life. We Also Discuss: Why "No Thoughts" is Meditation Mythology That Sabotages Your Practice The 6-Point Body Softening Technique That Works in 30 Seconds Why Your Hips Must Be Higher Than Your Knees for Proper Meditation Posture The Secret Taoist Water Meditation Scott Discovered by Accident Nadi Shodhana: The Daily Breathwork Practice That Changes Everything Why Scott Stopped Teaching Fire Breathing After Becoming Trauma-Informed How Mirror Neurons Transfer Meditative States Between People The 4 Lenses Framework: Waking Up, Growing Up, Cleaning Up, Showing Up Why Gurus Fall: Advanced States vs. Psychological Development Open-Eyed Meditation and Why Peak States Can Become Addictive The 3 Questions That Build Meditation Confidence in 30 Days Why You Should Stop While the Practice Still Feels Good   Thank You for Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Function Health: The first 1000 get a $100 credit toward their membership. Visit www.functionhealth.com/drshah or use gift code DRSHAH100 at sign-up to own your health.    Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Scott Schwenk: Instagram: https://www.instagram.com/thescottschwenk/  Website: https://www.scottschwenk.com/
Most people think thyroid issues are just about taking a pill, but over 90% of hypothyroid cases are actually Hashimoto's—an autoimmune condition attacking your thyroid gland. In this episode of Extend, I'm joined by Dr. Izabella Wentz to dive deep into why standard TSH tests fail for years, how artificial sweeteners trigger thyroid dysfunction, and the gut infections that could be destroying your thyroid. We also discuss the lifestyle interventions that can reverse Hashimoto's, the thyroid antibody tests your doctor isn't running, and why an Epsom salt bath might be more powerful than you think. Dr. Izabella Wentz, PharmD, is a clinical pharmacist who has dedicated her career to addressing the root causes of autoimmune thyroid disease after being diagnosed with Hashimoto's thyroiditis in 2009. She's the author of three books and founder of ThyroidPharmacist.com. We Also Discuss: Why Standard TSH Tests Miss Thyroid Disease for 5-10 Years The Complete Thyroid Panel Every Person Should Demand: TSH, T3, T4, Reverse T3, TPO, TG Antibodies How Artificial Sweeteners Trigger Autoimmune Thyroid Disease The Gluten-Thyroid Connection That Can Reverse Hashimoto's Gut Infections Behind Thyroid Dysfunction: H. Pylori, SIBO, and Blastocystis Hominis Why Thyroid Antibodies Attack Your Brain, Fertility, and Mental Health—Even Without Thyroid Hormone Problems The Selenium + Myo-Inositol Protocol That Reverses Early Hashimoto's Why Iron Deficiency Makes Thyroid Medication Useless Synthroid vs. Armour vs. T3: Which Thyroid Medication Actually Works The Hashimoto's Personality: Stress, Trauma, and Autoimmune Disease Red Light Therapy and Cold Laser for Thyroid Regeneration Why Your Thyroid Symptoms Might Actually Be Low Cortisol Thank You for Our Sponsors: Pendulum: Use code DARSHAN or use the link https://pendulumlife.com/discount/DARSHAN to get 20% off Pendulum membership first orders.   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Izabella Wentz Instagram: https://www.instagram.com/izabellawentzpharmd/  Website: www.thyroidpharmacist.com
What if the most basic safety research on childhood vaccines has never actually been done? In this episode of Extend, I sit down with Dr. Joel "Gator" Warsh, an integrative pediatrician who's asking the questions about vaccine safety that medicine has avoided for decades. We explore why vaccines are studied against other vaccines instead of true placebos, the shocking absence of vaccinated vs. unvaccinated research, and how financial incentives shape medical recommendations. Dr. Warsh also breaks down his approach to informed consent with parents. This isn't anti-vaccine rhetoric—it's a call for better science.  Dr. Joel Warsh is a board-certified pediatrician based in Los Angeles. After completing his residency at Children's Hospital Los Angeles, he became one of the few pediatricians to openly discuss vaccine safety concerns. He's the author of "Between a Shot and a Hard Place" and founder of Integrative Pediatrics and Medicine Studio City. We Also Discuss: Why Most Vaccines Were Never Studied Against True Placebos The Missing Vaccinated vs. Unvaccinated Research That Could End the Debate How Financial Incentives Drive Vaccine Recommendations The Autism Research That Doesn't Actually Exist MMR vs. Individual Protection: Why All Vaccines Aren't the Same The Hepatitis B at Birth Controversy for Low-Risk Babies Why Whooping Cough "Cocooning" Might Actually Increase Risk The Cleveland Clinic Flu Shot Study That Changed Everything mRNA Technology: What We Know vs. What We Don't After 4 Years Ultra-Processed Foods and the Real Driver of Childhood Illness Screen Time Strategies: Educational vs. Dopamine-Engineered Content The Social Contract Debate: Individual Rights vs. Public Health Thank You for Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH.   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Joel Gator Warsh Newsletter: https://raisingamazingplus.com/  Instagram: https://www.instagram.com/drjoelgator/?hl=en  Website: https://raisingamazingplus.com/inner-circle/
What if the device in your pocket is secretly sabotaging your metabolism, sleep, and longevity? In this episode of Extend, I sit down with Dr. Rupy Aujla, a medical doctor turned lifestyle medicine pioneer who reversed his own heart condition through food and lifestyle changes alone. We explore the "cocaine phone vs. kale phone" strategy for digital wellness, why fiber maxing on TikTok is backfiring, and how to get 10 servings of vegetables daily without thinking about it. He also reveals his three-pillar framework for optimal health. Dr. Rupy Aujla is a medical doctor with over 15 years of experience, bestselling cookbook author of "Healthy High Protein," and founder of The Doctor's Kitchen app. After reversing his own atrial fibrillation through lifestyle medicine, he left the NHS to help millions of people worldwide cook their way to better health through evidence-based nutrition and functional medicine principles. We Also Discuss: The "Cocaine Phone vs. Kale Phone" Strategy for Digital Detox Why Fiber Maxing on TikTok Is Making People Sick The Three-Pillar Framework: Protein, Gut Health, and Anti-Inflammatory Eating How Dr. Rupy Reversed Heart Arrhythmia Without Surgery The "Just One More" Philosophy for Adding Vegetables Why 5-a-Day Was Completely Made Up (And What You Actually Need) Core Protein + Plant Partner + Topper: The New Protein Formula Silent Retreats: Resetting Your Dopamine in 3 Days Morning Light and Movement: The Ultimate Energy Hack Why Your Kitchen Is More Powerful Than Your Medicine Cabinet The Virtual Dr. Rupy AI Coach Revolution Thank You for Our Sponsors: Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/  NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/  Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Rupy Aujla: YouTube: https://www.youtube.com/@doctors_kitchen  Instagram: https://www.instagram.com/doctors_kitchen/?hl=en  Podcast: https://podcasts.apple.com/gb/podcast/the-doctors-kitchen-podcast/id1316938642
What if three minutes in cold water could give you more confidence than years of therapy? In this episode of Extend, I sit down with Kristin Weitzel, a breathwork expert and cold plunge coach who has certified over 325 instructors worldwide in her approach to nervous system regulation. We explore how to use breathwork to downregulate your nervous system instead of just surviving the cold, and why women shouldn't fear the recent controversy around cold exposure. Kristin reveals her "ICE" method (Intentional Cold Exposure) and shares the free tools that can transform your mental resilience starting today. Kristin Weitzel is a breathwork expert, Sherpa Breath and Cold founder, and certified sauna master who has been pioneering nervous system optimization for over a decade. She specializes in helping women and athletes use cold exposure and breathwork to expand their window of tolerance and build unshakeable confidence in all areas of life. We Also Discuss: Why the Anticipation of Cold Plunging Is Worse Than the Cold Itself The "ICE" Method: Intentional Cold Exposure for Life Success How to DJ Your Nervous System for Optimal Performance Why Most People Are Cold Plunging Wrong (And Spiking Cortisol) The 2x Breathing Technique That Changes Everything Cold Plunging vs. Cryotherapy  Why Wim Hof Breathing Isn't Right for Everyone Sauna Secrets: The 3-Minute Rule Between Hot and Cold Free Cold Plunge Coaching Tools You Can Download Today Thank You for Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Function Health: The first 1000 get a $100 credit toward their membership. Visit www.functionhealth.com/drshah or use gift code DRSHAH100 at sign-up to own your health.    Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Kristin Weitzel: Website: https://www.sherpabreathandcold.com/  Instagram: https://www.instagram.com/kristinweitzelofficial/  Podcast: https://tr.ee/_aKc6TfA0K
What if the depression, brain fog, and weight gain you're experiencing isn't "just aging" but actually a treatable hormone deficiency? In this episode of Extend, I sit down with Sara Szal, MD, a Harvard-trained gynecologist who has revolutionized how we approach women's health. We dive into why 80% of women experience brain dysfunction during menopause, the shocking failure of conventional medicine's "birth control and antidepressants" approach, and Dr. Sara's "hormone therapy plus" model. Whether you're 35 and starting to notice changes or 65 wondering if you've "missed the boat," this conversation will transform how you think about aging as a woman. Sara Szal, MD is a Harvard-trained gynecologist, New York Times bestselling author of four books including "The Hormone Cure," and a leading authority on hormone optimization. With over 25 years of experience treating 25,000+ patients, she specializes in root cause analysis and personalized protocols for peak performance. We Also Discuss: The 100+ Symptoms of Perimenopause Most Doctors Don't Recognize Why Your Doctor Says Hormone Testing Is "Useless" (And Why They're Wrong) Bioidentical vs. Synthetic Hormones: What You Need to Know The 80% of Women Who Experience Cerebral Hypometabolism During Menopause Why FSH Levels Predict Alzheimer's Risk in Women Testosterone for Women: When It Helps and When It Hurts The "Cheating Nature" Argument Against Hormone Therapy (Debunked) Mitochondrial Health: The Key to Reversing Biological Age Hot vs. Cold Therapy for Mitochondrial Optimization Thank You for Our Sponsors: Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/  NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/    Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Sara Szal, MD: Website:https://www.saragottfriedmd.com/  Instagram:https://www.instagram.com/saragottfriedmd/
93% of Americans are metabolically unhealthy and don't even know it. In this episode of EXTEND, I sit down with Ben Azadi, metabolic health expert and New York Times bestselling author who transformed his life by losing 80 pounds after facing obesity, depression, and pre-diabetes at just 23 years old. We explore how one out of every four healthcare dollars is spent on diabetes and why your doctor probably isn't checking the one biomarker that could predict metabolic issues. We also dive into practical strategies for breaking free from the sugar-burning trap. Ben Azadi is a metabolic health coach, New York Times bestselling author of "Metabolic Freedom," and founder of the Keto Kamp podcast. After overcoming obesity and depression through lifestyle changes 17 years ago, he has dedicated his life to helping others achieve metabolic flexibility through ancient healing strategies like ketosis and fasting, combined with modern science. We Also Discuss: Why Fasting Insulin Is the Most Important Test Your Doctor Isn't Ordering The Whitehall 2 Study: 6-14 Years of Hidden Insulin Resistance "Mentally Obese": Understanding Depression's Connection to Food Why There Are No "Essential Carbohydrates" in Medical Textbooks Continuous Glucose Monitors: The Accountability Tool That Changes Everything The 44.4 Pound Weight Loss in 30 Days Case Study Metabolic Confusion: Why Diet Variation Beats Diet Dogma The Simple Swap from Sugar Burning to Fat Burning Single Ingredient Foods: The Beginner's Best Strategy Thank You for Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH.  Function Health: Learn more and join using functionhealth.com/drshah. The first 1000 get a $100 credit toward their membership. Visit https://www.functionhealth.com/drshah or use gift code DRSHAH100 at sign-up to own your health.   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Ben Azadi: Website: https://benazadi.com/  Instagram: https://www.instagram.com/thebenazadi/
What if I told you that an 18-year-old athlete had a testosterone level of 26 - when it should be near 1,000? In this episode of Extend, I sit down with Layne Kilpatrick, a pharmacist with over 30 years of experience who has been sounding the alarm about environmental toxins for years. We dive into the alarming decline in testosterone levels, how microplastics are literally everywhere, and why young, healthy men are showing up with fertility issues that would have been unthinkable decades ago. We also share actionable solutions to protect ourselves and our families. Layne Kilpatrick is a pharmacist and the driving force behind Hormone Specialist. He specializes in breaking down the science of hormones and everyday toxins, empowering both men and women to understand the root causes of hormone imbalances and take actionable steps to restore their vitality in a world filled with endocrine disruptors. We Also Discuss: Why Testosterone Levels Have Dropped 50% in 50 Years The 18-Year-Old Athlete with a Testosterone Level of 26 Microplastics vs. Nanoplastics: Size Matters for Toxicity The Paint on Glass Bottle Lids That's Contaminating Your Water PFAS: The "Forever Chemicals" Found in 100% of Breast Milk Samples The $200 Desktop Solution That Filters Microplastics HEPA Filtration: Why You Need Carbon Filters Too BPA-Free Doesn't Mean Safe: The Regrettable Substitution Problem Paper Cups and Straws: The Hidden Plastic Linings The Four-Step Action Plan to Protect Your Family Today Resources: Persistent Inert Substances Comparison: https://docs.google.com/document/d/1_kDzJzqFQN9m59IxfCtJKgc-n4qAlxgn/edit    Thank You for Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH.    Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Layne Kilpatrick: Website: https://www.hormonespecialist.net/  Instagram:https://www.instagram.com/hormonespecialist/
Did you know that functional practitioners have been using GLP-1 peptides safely for years—long before the Ozempic phenomenon hit mainstream medicine? In this episode of Extend, I talk with Dr. Tracey Stroup, a naturopathic doctor and peptide therapy expert, who reveals how the pharmaceutical industry's approach to semaglutide created unnecessary controversy.  We dive into what peptides actually are, why your body might be deficient, and how the "dose everyone to the max and leave them there forever" approach completely missed the mark. We also discuss the functional medicine approach to peptide therapy, including proper dosing, cycling protocols, and why you need comprehensive support—not just a prescription. Tracey Stroup, ND is a naturopathic doctor with over 27 years in health and wellness. She's been using peptide therapy in her practice for 5 years and is passionate about educating both practitioners and patients on the proper use of these powerful therapeutic tools. We Also Discuss: What Peptides Really Are: Natural Biological Signals, Not Synthetic Drugs Why the Ozempic Craze Created Unnecessary Peptide Controversy The Functional Medicine Approach vs. Pharmaceutical Protocols How to Use GLP-1s Properly: Dosing, Cycling, and Off-boarding Why Most People Are Peptide Deficient (And Don't Know It) BPC-157: The "Wolverine Peptide" for Gut Health and Injury Recovery Growth Hormone Peptides: CJC, Ipamorelin, and Natural Hormone Balance Injectable vs. Oral Peptides: When and Why Each Route Matters Why DIY Peptide Therapy Can Backfire (And What to Do Instead) The Insulin Connection: Why Peptide Therapy Isn't Actually New Thank You To Our Sponsors: Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah    Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Tracey Stroup, ND: Website: https://courses.traceystroupnd.com/ftn-home  Podcast: https://eatprayfaithwithtraceystroupnd.buzzsprout.com/  Instagram: traceystroup_eatprayfaith
What if the symptoms you've been told to "just deal with" during perimenopause could actually be addressed? In this episode of Extend, I sit down with Cynthia Thurlow, a nurse practitioner who left traditional cardiology to focus on women's health and metabolic medicine.  We explore why the medical system has failed women during menopause, the critical biomarkers your doctor probably isn't checking, and how the misinterpretation of one major study has left generations of women suffering unnecessarily. We also discuss why LDL cholesterol might not be the villain it's made out to be and how hormone replacement therapy could be one of the most important interventions for long-term health. Cynthia Thurlow is a nurse practitioner and intermittent fasting expert. She's the author of "Intermittent Fasting Transformation" and hosts the "Everyday Wellness" podcast. She specializes in helping women navigate perimenopause and menopause through lifestyle medicine and bioidentical hormone replacement therapy. We Also Discuss: The Women's Health Initiative Disaster: How One Study Damaged Generations of Women Why Your "Normal" Fasting Glucose of 95 Means You're Already in Trouble ApoB and Lp(a): The Heart Disease Markers Your Doctor Isn't Checking Dutch Testing vs. Blood Work: Which Hormone Tests Actually Matter The $100 Calcium Score That Should Be Routine After 40 Why 60-Year-Olds CAN Start Hormone Replacement Therapy GLP-1 Medications: Beyond Weight Loss to Metabolic Healing The Intermittent Fasting Mistakes That Wreck Women's Hormones Pellet Therapy vs. Patches: The Hormone Delivery Debate Why Statins Are the Most Over-Prescribed Drugs in History Dysautonomia and HRV: The Nervous System Signals You're Missing The Gut-Menopause Connection No One Talks About Thank You for Our Sponsors: Pendulum: Use code DARSHAN or use the link https://pendulumlife.com/discount/DARSHAN to get 20% off   IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH.    Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Cynthia Thurlow: Website: https://www.cynthiathurlow.com/  Podcast: https://www.cynthiathurlow.com/podcast  Instagram: https://www.instagram.com/cynthia_thurlow_/
The top 10 grossing drugs only help 1 in 4 to 1 in 25 people who take them. Yet they're still considered "evidence-based" and prescribed to millions. In this episode of Extend, I talk with Dr. Nick Norwitz, who reveals why you can't rely on population averages to fix your individual health problems. We explore why the medical system isn't designed to figure out what makes you unique, why "calories in, calories out" fails as a biological model, and how to become your own health scientist using the N=1 approach. We also discuss practical strategies for experimenting with your own biology, from testing ketogenic approaches to understanding why your results might be completely different from everyone else's. Dr. Nick Norwitz is a Harvard-trained MD/PhD who transformed his own health using metabolic interventions after conventional medicine failed him. He's known for his extreme self-experiments and scientific approach to personalized health optimization. We Also Discuss: Why Most "Evidence-Based" Treatments Don't Work for You The N=1 Approach: Becoming Your Own Health Scientist Why Population Averages Can't Predict Individual Results The Calorie Counting Myth That's Keeping You Stuck Ketogenic Diets: When They Work (And When They Don't) How to Design Your Own Health Experiments Why Bio-Individuality Trumps One-Size-Fits-All Solutions Escaping the "Normal" Trap in Modern Medicine   Thank You To Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH.    Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Nick Norwitz: Website:https://www.nicknorwitz.com/  YouTube: https://www.youtube.com/@nicknorwitzMDPhD/featured  Instagram: https://www.instagram.com/nicknorwitz/
What if everything you've been told about preventing heart disease is only half the story? In this episode of Extend, I sit down with Dr. Joel Kahn, a pioneering preventive cardiologist who's spent decades challenging the traditional approach to cardiovascular medicine. We explore why the 1961 Framingham risk factors represent an incomplete picture of heart disease, and the hidden culprits damaging your blood vessels every day. We also dive into why a $100 calcium score should be as routine as a mammogram, how your cooking methods could be aging your arteries, and the surprising connection between erectile dysfunction and heart attacks. Dr. Joel Kahn is a preventive cardiologist, author, and founder of the Kahn Center for Cardiac Longevity. He is one of the few cardiologists advocating for plant-based nutrition and comprehensive lifestyle medicine. He's written multiple books including "The Whole Heart Solution" and hosts "Heart Doc VIP" podcast.  We Also Discuss: Beyond Cholesterol: The 20+ Hidden Risk Factors Your Doctor Isn't Checking The $100 Test That Could Save Your Life (And Why Insurance Won't Cover It) Advanced Glycation End Products: How Your Barbecue Is Aging Your Arteries The Glycocalyx: Your Body's Secret Vascular Protection System Why Every Man with ED Needs a Calcium Score TMAO and the Dark Side of Choline Supplements Blood Pressure Devices That Work Without Pills The Trauma Surgeon with Perfect Arteries Despite Sky-High Cholesterol EECP Therapy: The NASA Technology Rebuilding Hearts Nitric Oxide: The Nobel Prize-Winning Molecule You're Probably Destroying ApoB vs. LDL: The One Number That Matters Most Why Listerine Might Be Sabotaging Your Blood Pressure Thank You for Our Sponsors: NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/    Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Joel Kahn: Website: https://www.drjoelkahn.com/  Instagram: @drjkahn
Why can't you open that jar anymore? Why does getting up from a chair feel harder than it used to? In this episode of Extend, I sit down with Dr. Amy Shah to explore the strength crisis happening to women in perimenopause.  We dive into the simple tests that reveal where you're losing ground—and why most women are shocked by their results. We also share the exercise formula that actually works for perimenopausal women, honing in on the key fact that it has to be movement you enjoy, because sustainability beats intensity every time. Dr. Amy Shah is a double board-certified physician specializing in allergy/immunology and internal medicine, and author of I'm So Effing Tired. She's a leading voice in women's health, focusing on the intersection of hormones, gut health, and metabolism. We Also Discuss: The Grip Strength Test That Predicts Your Longevity (Most Women Fail) The Sit-to-Stand Test: Your Lower Body Strength Report Card Exercise Snacks: Why 10 Squats Every Hour Beats a 30-Minute Walk The Weighted Vest Mistake That's Wasting Your Time Why Jumping on a Trampoline Builds Stronger Bones Than Running Intermittent Fasting for Women: Why Daily Fasting Backfires Thank You To Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH.   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Amy Shah: Website:https://amymdwellness.com/  Book: I'm So Effing TiredX: https://x.com/amyshahmd
What if I told you there's an organ in your body with more cells than the Milky Way has stars—and most doctors barely think about it? In this episode of Extend, I sit down with Dr. Zain Kassam, a gastroenterologist turned microbiome researcher who's pioneering how we understand the trillions of organisms living in and on us.  We dive into why your gut bacteria aren't just bystanders—they're actively producing molecules that affect your mood, metabolism, immune system, and even longevity. We also explore the gut-brain connection, why not all probiotics are created equal, and how the microbiome influences everything from depression to skin health.  Dr. Zain Kassam is a gastroenterologist, microbiome researcher, and Chief Medical Officer at Seed Health. He trained at McMaster University, Harvard, and MIT, where he pioneered clinical applications of microbiome science. He's led groundbreaking research on fecal transplants and develops evidence-based probiotic therapies.   We Also Discuss: The Microbiome Revolution: From Forgotten to Life-Saving Why Your Gut Has More Cells Than the Milky Way Has Stars How Gut Bacteria Control Your Brain and Mood The Butyrate Connection: Your Microbiome's Master Molecule Why Most Probiotics Are Marketing Hype (And How to Choose Better) The 4D Framework: Diversity, Delivery, Do-Gooders, and Data Microbiome Testing: Crystal Ball or Expensive Guesswork? From C. Diff to Cancer: When Gut Health Becomes Life or Death The GLP-1 Secret: How Your Gut Makes Its Own Ozempic Post-Antibiotic Recovery: Rebuilding After the Nuclear Bomb   Thank You for Our Sponsors: Pendulum: Use code DARSHAN or use the link https://pendulumlife.com/discount/DARSHAN to get 20% off   IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH.    Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/     Learn more about Dr. Zain Kassam: X: https://x.com/DrZainSays/  Instagram: https://www.instagram.com/seed/ Get 25% off DS-01 with code EXTEND25 at Seed.com
Oxidative stress. Toxin overload. Immune dysfunction. These aren't separate problems—they're all symptoms of your body working overtime on one exhausting job. In this episode of Extend, I sit down with Dr. Nayan Patel, a pharmacist who's dedicated his career to understanding glutathione—the molecule your body produces more than any other.  We break down the three proven ways glutathione protects you, why IV and oral supplements have been failing for decades, and the gene mutations that leave 20% of people unable to benefit from traditional glutathione therapy. Most importantly, we discuss the stable glutathione breakthrough that's helping doctors reverse decades of brain fog in minutes. Nayan Patel, Pharm.D, is a pioneering pharmacist and researcher who discovered the first stable form of glutathione in 2007. His 25-year journey to unlock this master antioxidant has led to revolutionary insights about aging, detoxification, and immune function. We Also Discuss: Why Your Body's #1 Job Is Slowly Killing You (And How to Take It Over) The 100+ Daily Toxins Your Liver Must Process (You Can't Avoid Them) Glutathione's Triple Threat: Antioxidant, Detox, and Immune Power Why IV Glutathione Fails: The Shocking Truth About What Really Happens The Gene Factor: 20% of People Can't Use Traditional Glutathione (Are You One?) From Brain Fog to Clarity: Why Some See Results in 5 Minutes Thank You To Our Sponsors: Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah  IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH.   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Nayan Patel, Pharm.D: Website:https://aurowellness.com/ Instagram: @aurowellness Book: https://aurowellness.com/glutathione-revolution/
Low energy, brain fog, and poor recovery aren't just part of getting older—they're often signs that your cells are underperforming. And one major reason? They're starved for oxygen. In this episode of Extend, I talk with Dr. Scott Sherr, a hyperbaric medicine specialist who helps patients and doctors worldwide use oxygen therapy to restore cellular health. We get into what hyperbaric oxygen therapy (HBOT) actually does—not just more oxygen, but how it shifts gene expression, activates stem cells, and supports mitochondrial repair. We also discuss who shouldn't jump into HBOT too soon, and why testing antioxidant capacity and metabolic function is essential before starting. This isn't a quick fix—it's a targeted tool that works when your system is ready. If you're dealing with lingering symptoms or want to stay sharp and resilient long-term, this episode gives you a clear understanding of how HBOT fits into a true healthspan strategy. Dr. Scott Sherr is a board-certified internist and global expert in hyperbaric oxygen therapy, with over 20 years of clinical experience. He helps patients and physicians use HBOT to improve recovery, brain health, and long-term cellular function. We Also Discuss: The Real Goal: Longevity and Feeling Amazing Why Most Longevity Advice Misses the Mark Oxygen as Medicine? Inside Hyperbaric Therapy What Actually Happens in a Hyperbaric Chamber Can Oxygen Reverse Inflammation and Fatigue? Using Hyperbaric for Energy, Focus, and Recovery Thank You to Our Sponsor: IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Scott Sherr: Website: https://www.hyperbaricmedicalsolutions.com Instagram: https://www.instagram.com/drscottsherr/
Fatigue, brain fog, joint pain, blood pressure that won't budge, these aren't isolated symptoms. They're your cells signaling that something's off. In this episode of Extend, I sit down with Dr. Bill Rawls, a board-certified OB/GYN who now focuses entirely on cellular health. We explore why most chronic illness isn't about your diagnosis, it's about what's happening inside your cells. We share the five things every cell needs to function, and what happens when they don't get them. We also dig into stealth infections like Lyme and Epstein-Barr, and how they stay dormant for years until your body breaks down. Most importantly, we talk solutions: why herbs work when antibiotics don't, how to support your immune system without overstimulating it, and what real healing looks like. Dr. Bill Rawls is a board-certified physician and author of The Cellular Wellness Solution. His personal health crisis with chronic Lyme led him to develop Restore180, a protocol that's helped thousands recover from chronic illness by restoring cellular function. We Also Discuss: Why Chronic Illness Keeps Coming Back (And What We're Getting Wrong) The 5 Things Every Cell Needs to Heal (You're Missing at Least One) Lyme, EBV, Mold: How Hidden Infections Hijack Your Cells Sick Cells, Silent Symptoms: The Real Root of Chronic Disease Herbs vs. Antibiotics: Why One Heals and the Other Harms Thank You To Our Sponsors:   Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah    Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Bill Rawls: Website: https://rawlsmd.com/ Program: restore180.comInstagram: @rawlsmd
Your doctor says your health problems are genetic, so you're destined for the same fate. But what if that's completely wrong? In this episode of Extend, I'm joined by Professor Tim Spector, one of the world's leading microbiome researchers, to reveal the truth: your gut bacteria have more control over your health than your genes do. We explore Tim's 30-year twin study that turned modern medicine upside down, the devastating effects of antibiotics on your internal ecosystem, and why ultra-processed foods are as dangerous as cigarettes. We also dive into why 95% of Americans are dangerously fiber-deficient, and how fermented foods can reduce inflammation like natural steroids.   Professor Tim Spector is a genetic epidemiologist at King's College London, co-founder of Zoe, and author of multiple bestselling books on the microbiome. His research on 16,000 twins has revolutionized our understanding of how gut health trumps genetics in determining health outcomes.   We Also Discuss: (02:18) 30 Years of Twin Research: The Study That Changed Everything  (08:35) The Antibiotic Crisis: Why Your Childhood Meds Are Still Hurting You  (11:31) C. Diff and the First Clue About Good vs. Bad Bacteria  (22:40) Why Your Gut Microbiome Matters More Than Your Genetics  (30:30) The Hidden Connection Between Gut Health and Autoimmune Disease  (35:39) Ultra-Processed Foods: The Modern Cigarette Industry  (43:51) Why 95% of Americans Are Fiber-Deficient (And Obsessed with Protein)  (58:58) The 30 Plants Challenge: Diversity Over Restriction  (01:05:22) Sourdough Secrets: Real vs. Fake (Most Is Fake)  (01:13:46) Inside the Zoe Kit: Personalized Nutrition Based on Your Biology  (01:19:53) GLP-1 Drugs: The Perfect Window for Gut Health Reset  (01:27:36) Prebiotics vs. Probiotics vs. Postbiotics: What Actually Works  (01:41:29) The Food for Life Cookbook: 100 Recipes for Your Microbiome Thank You for Our Sponsors:   TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/IM8: Get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH.   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Professor Tim Spector: Instagram: @tim.spector Website: https://zoe.com/en-us  Pre-Order Ferment
What if the real reason you're gaining weight, feeling wired, or struggling to nourish your family isn't about willpower—but the culture you live in? On this episode of Extend, I'm joined by Shawn Stevenson—nutritionist, bestselling author, and host of The Model Health Show—to explore how our food environment, not personal discipline, is fueling the chronic disease crisis. If you're raising kids, trying to eat better, or just feel overwhelmed by ultra-processed foods, this conversation cuts through the noise. We unpack the science behind shared meals, how family dinner regulates your stress hormones, why many "healthy" foods aren't, and what it takes to create a home culture that supports real health. Shawn Stevenson is a bestselling author, nutritionist, and the creator of The Model Health Show, which has ranked as the #1 health podcast in the U.S. He's the author of Eat Smarter and The Eat Smarter Family Cookbook, blending nutrition science with practical strategies for home-cooked meals that heal.   We Also Discuss: This Isn't About Food. It's About Culture. One Meal That Lowers Disease Risk? Why You're Craving What You Crave How Ultra-Processed Foods Hijack Your Brain Seed Oils, Satiety & the $1 Lie "Healthy" Labels Are Lying to You Calories Aren't the Problem. This Is. The Longevity Hack No One Talks About: Dinner Together Thank You for Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/Nexthealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Shawn Stevenson:   Website: themodelhealthshow.com Instagram: @shawnmodel
Back pain is one of the most common health issues—but it's also one of the most misunderstood. In this episode of Extend, I'm joined by Dr. Grant Elliott, a physical therapist and founder of RehabFix, to unpack the real reasons people stay stuck in chronic pain and what it actually takes to recover. We break down why most diagnoses like sciatica or disc herniation are misleading, why MRIs often make things worse, and how the brain and body respond to fear-based treatment approaches. Dr. Elliott shares the daily habits and mindset shifts that move the needle most, plus how to bulletproof your spine with simple strength and mobility practices. We also dive into the problem with gabapentin and pain meds, how to get back to exercise safely, and what most people miss when trying to heal holistically. Dr. Grant Elliott is a physical therapist, creator of RehabFix, and expert in conservative, movement-based solutions for back pain. He's helped thousands avoid surgery and reclaim their mobility through education, strength, and smarter recovery protocols. We also discuss:   Your MRI says "herniated disc"—but you feel fine? How MRIs can make back pain worse Why movement is medicine for your spine 97% of disc herniations heal on their own The nervous system: the hidden driver of pain Weird symptoms? Your spine might be the reason (even ED)   Thank You to Our Sponsors: Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age!  Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Grant Elliott: Instagram: https://www.instagram.com/rehabfix/ Website: https://www.therehabfix.com/ Facebook: https://web.facebook.com/grant.elliott.39?_rdc=1&_rdr# YouTube: https://www.youtube.com/channel/UCEIuFir2D63x9a1FWWEGqZw
You're bloated. Tired. Anxious. Maybe even burnt out. You've tried the diets, the supplements, the meditation apps… But you're still not healing. Why? In this episode of Extend, I'm joined by Elissa Goodman, a holistic health expert and cancer survivor, to explore the deep connection between gut health, inflammation, and overall well-being. We dive deep into the science behind food resets, the importance of eliminating inflammatory foods, and the role of personalized blood work in identifying hidden health imbalances. And also discuss practical strategies for improving digestion, boosting energy, and supporting long-term health through a balanced diet and stress management. By the end of this episode, you'll walk away with actionable insights to help your body reset, reduce inflammation, and improve both your mental and physical health, starting with your gut. Elissa Goodman is a holistic nutritionist specializing in gut health, personalized food resets, and functional nutrition. After overcoming cancer, she combines conventional and alternative therapies to restore health and reduce inflammation. We Also Discuss: (00:02) What Sparked a Lifelong Mission to Heal? (03:56) Wellness Trends: Game-Changers or Gimmicks? (14:36) Only Eating 3 Veggies? Here's Why That's a Problem (18:35) Struggling with Bloating? This Might Be Your Missing Link (25:20) Detox Myths Busted—Here's What Actually Works (31:55) The Healing Strategy You're Probably Overlooking (43:30) The Real Reason You're Tired (It's Not Just Sleep) (51:17) Mindset Over Medicine? A Radical Healing Shift (01:14:05) The Supplements Elissa Actually Recommends Thank You for Our Sponsors:   TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/IFit:If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Elissa Goodman: Website: https://www.elissagoodman.comInstagram: https://www.instagram.com/elissagoodman
What if your bloating, fatigue, or fertility struggles aren't separate issues, but signs of a deeper imbalance no one's connected yet? In this episode of Extend, I'm joined by Dr. Robin Berzin, founder of Parsley Health, and we dig into how functional medicine uncovers the why behind your symptoms and why conventional care keeps missing it. We talk about the most overlooked root causes of chronic illness, the truth about blood sugar and hormones, and why fertility issues are often metabolic in disguise. You'll also learn how functional medicine works in real life, how to find the right provider, and why Dr. Berzin created her "brains, bones, and booty" framework for aging well—especially for women. Dr. Robin Berzin is a Columbia-trained MD, pioneer in reimagining primary care and author of State Change. She's helped thousands of patients get off the prescription treadmill and finally feel like themselves again. We Also Discuss: The wake-up call that changed everything Why most functional medicine was failing How functional care actually works The blood sugar-hormone connection no one talks about Brains, bones, and booty: the new longevity framework for women The real reason your mental health symptoms won't go away What no one tells women between pregnancy and menopause The hidden crisis in kids' health—and what to do about it Thank You to Our Sponsors:   TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Robin Berzin:   Instagram: @robinberzinmd Instagram:@parsleyhealth Website: https://robinberzinmd.com
What if the root cause of burnout, inflammation, and hormone dysfunction isn't just physical—but energetic? In this episode of Extend, I sit down with Dr. Pedram Shojai—Taoist monk, doctor of Oriental medicine, and author of The Urban Monk—to explore how ancient wisdom meets modern health. We unpack why true healing requires addressing your qi (life force), how emotional stagnation leads to physical disease, and why regulating your energy is just as important as optimizing your bloodwork. From the microbiome to meditation, Dr. Pedram shares how restoring energetic flow can radically shift your metabolism, mood, and even your fertility. And we go deep on what most functional medicine still misses about the connection between spiritual vitality and long-term health. Dr. Pedram Shojai is a former Taoist monk, acclaimed filmmaker, and best-selling author who's helped millions reconnect with their body, breath, and purpose. His work bridges ancient healing systems with today's most pressing health challenges. We Also Discuss: How blocked energy leads to chronic illness The missing layer in functional medicine The ancient view of fertility and hormones Why energy management is the new stress management The true purpose of breathwork and meditation How to reclaim your life force in a modern world Why we can't separate emotional and physical healing The nervous system patterns that keep you sick   Thank You To Our Sponsors: Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Pedram Shojai   Instagram: @drpedramshojaiWebsite: www.theurbanmonk.com
What if your exhaustion, brain fog, or cravings aren't a motivation problem—but a sleep problem no one's diagnosed yet? In this episode of Extend, I'm joined by Dr. Michael Breuss, a sleep specialist, and we dig into why so many high performers are chronically under-recovered, why sleep disorders go undetected for years, and how wearables are both helping and hurting. We talk about why 8 hours might be the wrong goal, how your chronotype should determine your schedule, why snoring isn't harmless, and the link between GLP-1s and sleep apnea. You'll also learn how mouth tape works, the surprising truth about blue light, and why most hydration habits fail. Dr. Michael Breus is a clinical psychologist, board-certified sleep specialist, and the author of five books on sleep. He's worked with Olympic athletes, celebrities, and CEOs—and in this conversation, he's bringing you the same level of clarity and insight.   We Also Discuss: Why Sleep Disorders Go Undiagnosed for Years The Truth About Sleep Trackers and Deep Sleep Scores Is Your Bedroom Air Ruining Your Sleep? Mouth Tape: Helpful or Harmful? GLP-1s for Sleep Apnea? Here's What the Science Says Your Sleep Needs Change With Your Period Morning Breathwork That Replaces Coffee Sip vs Gulp: Are You Drinking Water Wrong? Thank You To Our Sponsors:   TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Michael Breus    Instagram: @thesleepdoctorWebsite: https://sleepdoctor.com
Most people focus on physical health. But after years of practicing medicine, I've seen this truth again and again: you can't heal your body if your mind and nervous system are stuck in survival mode. In this episode of Extend, I sat down with Kelly Gores, creator of HEAL and founder of WellSet, to explore how trauma, stress, and emotional blocks drive chronic disease—and what it really takes to heal. We dive into the science behind the placebo effect, how intuition works, why regulating your nervous system is foundational for longevity, and the simple daily practices that can completely shift your biology. Kelly Gores is the writer, director, and producer of HEAL Documentary, and  the founder of WellSet, a platform bringing holistic healing practices to a wider audience.  We Also Discuss: Why healing can't happen in fight-or-flight  How modern life keeps your body stuck in survival mode  The real reason most people block their own healing  Why intuition is a biological survival tool, not "woo"  How your subconscious mind controls 95% of your health Why 70% of healing has nothing to do with food or fitness  The key mindset shift that triggers deep physical healing  Thank You To Our Sponsors:   Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah  Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Kelly Gores:   Instagram: @kellygores Instagram (HEAL Documentary): @healdocumentary Website: https://www.healdocumentary.com HEAL Book: Here
What if aging isn't just inevitable—but programmable? In this episode of Extend, I sit down with Dr. Kara Fitzgerald, pioneering epigenetic researcher and author of Younger You, to explore how your daily choices—food, movement, sleep, stress—can literally rewire your genes to slow down aging. We unpack her groundbreaking study showing biological age reversal in just 8 weeks without drugs, injections, or extreme protocols. You'll learn how DNA methylation impacts everything from inflammation to longevity, which "epinutrients" flip your genes in the right direction, and why your salad might be more powerful than your supplement stack. Dr. Kara Fitzgerald is a functional medicine physician. Her clinical trial was the first to show biological age reversal through diet and lifestyle alone. She's also the author of Younger You. Let's get into it. We Also Discuss: How she helped reverse biological age in 8 weeks The one test that reveals how fast you're actually aging Can food really reprogram your genes? (Spoiler: yes) Why folate, B12, and mushrooms might be more powerful than your multivitamin The "epinutrients" your aging cells are starving for Why your salad might be more effective than supplements Is the carnivore diet speeding up your biological age? What Yamanaka factors, vitamin D, and plasma exchange mean for your future Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/Ifit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr.Kara Fitzgerald:    Website: https://www.drkarafitzgerald.com/  Instagram: @drkarafitzgerald  Book: Younger You
Most people are treating stress with the wrong tools, and it's silently sabotaging their longevity. In this episode of Extend, I sit down with Jen Batchelor, Ayurvedic health optimizer and co-founder of Kin Euphorics, to talk about what your nervous system actually needs to feel calm, connected, and well. We dive into what adaptogens are really doing in your body, why saffron might be one of the most powerful neuroprotective tools available, and how homeostasis—not hustle—is the key to better energy and long-term health. We also explore the hidden costs of loneliness, the biology behind joy, and why redefining pleasure might be the most underrated health hack of all. Jen Batchelor is the co-founder of Kin Euphorics, a non-alcoholic beverage company blending adaptogens, nootropics, and ritual to support mood, connection, and recovery We Also Discuss: Adaptogens aren't supplements—they're system whisperers Saffron for your brain? Yep, it's a thing The 30-second nervous system reset you're not doing She went from desert moonshine to alcohol-free empire Longevity hack? Real connection > green juice  Use code EXTEND20 to get 20% off at kineuphorics.com. Thank You to Our Sponsors:   Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age!  Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Jen Batchelor: Website:https://www.kineuphorics.com/  Instagram: https://www.instagram.com/kineuphorics/  Instagram: https://www.instagram.com/jenofkin
What if your real age isn't on your driver's license—but buried in your biology? In this episode of Extend, I'm joined by Chris Mirabile, founder of NOVOS and one of the few people actually slowing down his pace of aging. We break down why the average person is aging faster than they realize, and how mainstream medicine is decades behind when it comes to prevention. We get into the 12 hallmarks of aging, why free radicals aren't your enemy, how biological clocks really work, and the lifestyle and supplement strategies that are scientifically shown to make you younger from the inside out. Chris Mirabile is the founder and CEO of NOVOS, a longevity biotech company backed by leading researchers and data. After surviving a brain tumor at age 16, he became obsessed with the science of living better, longer. Let's dive in. We Also Discuss: Why Healthspan Matters More Than Lifespan 12 Cellular Reasons You're Aging Faster Than You Should Mitochondria, Free Radicals, and the Truth About Energy Decline Can We Reprogram Aging? The Science Behind Epigenetics The Real Pathways to Longevity (That Most Doctors Ignore) How Your Daily Habits Are Speeding Up—or Slowing Down—Aging What Your Biological Age Says About Your Future Health From Supplements to Stem Cells: What Actually Works to Slow Aging   Thank You to Our Sponsors:   TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Chris Mirabile   Website: https://slowmyage.com/ Instagram: https://www.instagram.com/slowmyage
Most supplements don't work. Some might actually harm you. That's the hard truth no one in the $50 billion supplement industry wants to say out loud—but we will. In today's episode of Extend, I'm joined by Steve Martocci, co-founder of SuppCo, to expose what's really going on behind the labels. We break down why "clinically dosed" means nothing, why the FDA isn't protecting you, and how two identical bottles can deliver completely different outcomes. We also dive into the myth of "FDA-approved" supplements, the loopholes brands exploit to mislead consumers, and why Europe bans ingredients still allowed in U.S. formulas. If you take supplements—or recommend them—this episode is essential listening. It's time to stop guessing, stop wasting money, and start demanding real data, transparency, and strategy. Steve Martocci is the co-founder of SuppCo, a platform bringing science-backed clarity to the chaos of the supplement industry. We Also Discuss: The dirty truth behind supplement "trust scores" How shady supplements keep making it to your shelf Supplement demand is exploding… but quality isn't Why "clinically dosed" doesn't mean clinically effective How professional brands still get away with underdelivering Why you're probably taking the wrong supplements for your goals How SuppCo is flipping the industry on its head The tool that finally helps you trust what you're taking Thank You For Our Sponsors:   Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah  Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Steve Martocci: Instagram: https://www.instagram.com/smart/ Instagram: https://www.instagram.com/joinsuppco/  Website: https://supp.co/  ➡️ Listeners can use the code "EXTEND15" to receive 15% off their personalized supplement protocol on https://supp.co/
What if the reason you can't focus, feel chronically overwhelmed, or keep slipping into the same unhealthy habits… isn't a discipline problem, it's your brain's biology working against you? In this episode of Extend, I'm joined by Dr. Austin Perlmutter, board-certified internal medicine physician and neuroscientist, to explore how inflammation hijacks your brain's decision-making and what you can do to take back control. We dig into why modern life wires your brain for reactivity over intention, the shocking impact of neuroinflammation on mood and behavior, and how daily habits are either fueling the fire or calming the system. You'll learn practical tools to reduce brain-body inflammation, support cognitive clarity, and make better choices even under stress. Dr. Austin Perlmutter, MD is a board-certified internal medicine physician, neuroscientist, and New York Times bestselling author. Let's dive in!   We Also Discuss: Why Brain Health Isn't Just in Your Head The Overlooked Link Between Metabolism and Mental Clarity What Chronic Inflammation Is Really Doing to Your Brain How Long-Term Stress Rewires Your Biology Rethinking Depression: It's Not Just in the Mind Can You Rewire Your Brain? The Science of Neuroplasticity Are Psychedelics the Future of Mental Health? The Brain-Sleep Connection You Can't Afford to Ignore Thank You to Our Sponsors:   TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Austin Perlmutter:   Website: https://www.austinperlmutter.com/ Instagram: https://www.instagram.com/draustinperlmutter/ Lichen air: Get 10% off at https://lichen-air.myshopify.com/?rfsn=8715882.7adc91 using code DRSHAH10   Sources: Effects of different physical activities on brain-derived neurotrophic factor   Dr. Austin's research on Tartary Buckwheat: www.bigboldhealth.com
In this episode of Extend, we're digging into one of the most dangerous—and most overlooked—drivers of heart disease: LP(a). You could have a clean lifestyle, normal labs, and still be at high risk for a heart attack or stroke. Why? Because LP(a) isn't included in standard cholesterol tests—and 1 in 5 people have elevated levels without knowing it. I break down what LP(a) actually is, why it's more inflammatory and damaging than LDL, and how it contributes to plaque, heart attacks, strokes, and valve disease. You'll learn why lifestyle changes don't lower it, what to do if your levels are high, and how cutting-edge RNA therapies could offer hope. I also share exactly which labs and scans to request so you're not flying blind. ➡️ If you care about preventing cardiovascular disease, this is essential listening. It's time to add LP(a) to the conversation. I Also Discuss:   The stealth cholesterol marker no one's testing for Think your cholesterol panel is fine? Here's what it's missing LP(a): the hidden culprit behind "healthy" heart attacks This could be why young people are having strokes The one stat that should have everyone talking Got high LP(a)? Here's your action plan The game-changing drugs that silence LP(a) at the source   Thank You for Our Sponsors: Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com    Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
What if the reason you're tired, inflamed, or not recovering the way you used to has nothing to do with aging, and everything to do with your NAD system being under attack? In this episode of Extend, I'm joined by Dr. Charles Brenner, the scientist who discovered nicotinamide riboside (NR) and one of the leading experts on NAD metabolism. We unpack why NAD is so critical for energy, repair, and resilience, and why simply "taking NAD" isn't the solution most people think it is. We also break down the key lifestyle factors quietly draining your NAD levels, the real difference between NMN, NR, niacin, and IV NAD, and why NR may be the safest and most effective way to support your body's natural repair systems. Dr. Brenner also shares the science behind NAD's role in inflammation, immunity, and recovery, and why placebo-controlled research is the missing piece in so many longevity conversations. Dr. Charles Brenner is the Alfred E. Mann Family Foundation Chair in Diabetes and Cancer Metabolism at City of Hope and a leading authority on NAD metabolism. His work bridges fundamental science with real-world application. We Also Discuss: Why NAD Is the Missing Link in Energy, Repair, and Longevity The Truth About NAD Decline—and What's Really Draining Your Levels NR vs. NMN: The NAD Debate That Actually Matters Is Oral NR Better Than IV NAD? Here's What the Research Says How NAD Impacts Inflammation, Immunity, and Recovery The Gaps in NAD Science and Why They Matter Thank You to Our Sponsors:   TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Charles Brenner: Website: brennerlab.netInstagram: @charlesmbrenner
Most people know mindset matters, but almost no one knows how to actually train it for better health, performance, and longevity. In today's episode of Extend, I'm joined by David Nurse, NBA mindset coach and best-selling author. We dive deep into why mindset is the real missing piece in most health optimization plans, and how flow states, identity shifts, and daily systems can radically change your outcomes.    We also break down why your mindset is the ignition switch for success, how to tap into flow states more consistently (and why it matters), the truth about goals vs. systems, and why goals alone fail, how identity shapes your health, your results, and your future, and actionable tools you can start using today to rewire your brain for growth.   David Nurse is a top NBA mindset coach, best-selling author, and motivational speaker specializing in high-performance habits. David is the author of Pivot & Go, Breakthrough, Do It, and the upcoming book The Flow Code. Tune in! We Also Discuss: • How the Health Optimization Summit Changes Your Mindset Game • Why Flow States Are the Missing Link to Peak Performance • Focus vs. Flow: Why Most People Get It Wrong • Simple Tools to Build Unshakable Confidence and Reset Fast • The 4-Step Formula to Trigger Flow on Command • Why Chasing Goals Alone Kills Your Momentum • The Morning Routine that Rewires Your Brain for Success • Encouragement, Habits, and the Real Secret to Sustainable Growth Thank You for Our Sponsors:   Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com  Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram:@darshanshahmd   Learn more about David Nurse Instagram: @davidnursenbaTwitter: @DavidNurseNBA YouTube: David Nurse
What if the hidden toxins in your everyday life are secretly sabotaging your health, hormones, and longevity? Most people underestimate how deeply their health is impacted by toxins—and conventional medicine isn't addressing the root of the issue. In this episode of Extend, I'm joined by Dr. Aly Cohen, renowned integrative rheumatologist, environmental health expert, and author of the upcoming book, Detoxify. We uncover the shocking truth about the tens of thousands of unregulated chemicals lurking in your home, food, water, and even your skincare products—and reveal why detox isn't about trendy cleanses, but smarter daily choices. We dive into why microplastics have infiltrated every part of your body (including your brain), how seemingly innocent products are disrupting your hormones, metabolism, and immune system, and what practical steps you can immediately take to dramatically reduce your toxic exposure. Dr. Cohen shares eye-opening facts on why your tap water is more polluted than you think, why household dust is toxic waste in disguise, and how simple nutritional strategies can powerfully protect you from environmental harm. We Also Discuss: Detox Myths That Even Most Doctors Believe The Shocking Truth About How Toxins Sabotage Your Immune System Easy Daily Habits to Dramatically Reduce Your Toxic Load Why Reverse Osmosis Is a Non-Negotiable for Your Health Practical Tips to Navigate a Toxin-Free Lifestyle (Without Stress) Hidden Sources of Microplastics You Use Every Single Day Detox Done Right: Supporting Your Liver & Kidneys Naturally The "Four A's" Method to Protect Your Health from Hidden Chemicals   Thank You to Our Sponsors:   TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Aly Cohen: Website: www.alycohenmd.com  Instagram: @TheSmartHuman
In this episode of Extend, we're rethinking everything you've been told about cholesterol. For decades, the focus has been on lowering LDL, but that's only part of the story. The truth? LDL and total cholesterol are outdated metrics. If you're still relying on those alone to assess your heart health, you're missing the bigger picture. I'll break down why ApoB is the single most important number to track when it comes to cardiovascular disease, and how it gives a much clearer view of your real risk. You'll learn how plaque forms, why inflammation and metabolic dysfunction matter just as much as cholesterol, and how to approach your heart health with precision. I'll also cover how to lower ApoB naturally, when medication might make sense, and how advanced scans like CLEARLY can help guide your strategy. ➡️If longevity is your goal, this episode is a must-listen. Let's move beyond outdated labs and into next-gen heart prevention.   I Also Discuss:   Why LDL Is Outdated (And What to Track Instead) The Real Cause of Plaque in Your Arteries ApoB: The #1 Biomarker for Heart Health How to Lower Cholesterol Without Statins The Longevity Approach to Cardiovascular Disease Thank you for our Sponsors:   Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com    Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
What if the secret to better energy, fat loss, and gut health wasn't more discipline… but a smarter strategy? Most people are hacking the wrong system—and it's backfiring. In this episode of Extend, I'm joined by Joel Greene, creator of the VEEP Nutrition System and one of the most innovative minds in metabolic health. We break down the science behind fat loss, blood sugar regulation, gut health, and why conventional diet advice is failing most people. We dive into how your microbiome controls more than just digestion, why fasting isn't one-size-fits-all, and what your body really needs to burn fat and build lasting energy. Joel also shares cutting-edge insights on short-chain fatty acids, protein misconceptions, and how your environment is silently shaping your metabolic function. If you want to understand how your body actually works—and how to fuel it for longevity and performance—this conversation is a game-changer.   We Also Discuss: How the Wellness Industry Got It All Wrong The Hidden Link Between Poor Sleep and Your Diet From Sick to Superhuman: Joel's Radical Health Turnaround The Forgotten Foods That Heal Your Gut Why Most Gut Protocols Fail (And What to Do Instead) Think You're Eating Healthy? Think Again. The Missing Piece in Every Metabolic Plan It's Not Just What You Eat—It's When and How   Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Joel Greene:   Website: https://www.veepnutrition.com/  Instagram: https://www.instagram.com/realjoelgreene/?hl=en
What if our food system wasn't designed for our health, but for shelf life, convenience, and corporate profit? In today's episode of Extend, I'm joined by Ricky Silver, CEO of Daily Harvest, who brings a rare inside-the-industry view of how our food system really works, and how we can change it. We explore how government subsidies, processed foods, and industrial farming practices have led to the chronic disease crisis we're facing today. We dig into why frozen organic produce is a nutritional powerhouse, what regenerative agriculture actually means, and how everyday consumers like you and me can help shift the food industry toward something more nourishing, for people and the planet. Whether you're someone who shops organic or you're just beginning to question what's really in your food, this episode will empower you to make smarter choices and push for systemic change. Ricky Silver is the CEO of Daily Harvest, a company focused on making organic, plant-based meals accessible and convenient. He brings a unique perspective on the intersection of science, food, and health. Let's get into it. We Also Discuss: Why "Organic" Isn't Just a Label—It's a System Shift How Your Grocery Cart Can Change the Food Industry The Real Reason Our Food Is Making Us Sick From Profit to Purpose: Rethinking the Food System's North Star What Farmers Really Want—and Why We Should Listen The Untold Truth About Gluten, Glyphosate, and Gut Health Thank You for Our Sponsors:   Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com  Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Ricky Silver: Website: https://www.dailyharvest.com Instagram: @dailyharvestInstagram: @rickyjsilver
What if the reason your supplements aren't working has nothing to do with your body—and everything to do with what's in the bottle? In this episode of Extend, I'm joined by biochemist and ingredient formulator Shawn Wells, a leading voice in evidence-based supplementation and mitochondrial health. Together, we uncover why so many products fail to deliver results, how to build a smarter, personalized stack, and what most people get completely wrong about vitamins, probiotics, and biohacking. We get into the dangers of proprietary blends, why over 80% of supplements on Amazon may be underdosed or inactive, and what blood tests and wearables really reveal about your health. Shawn also shares his foundational stack—from GLP-1 agonists to mitochondrial protectors—and explains why dosing and timing matter more than you think. If you're relying on guesswork when it comes to supplements, this episode will change your approach for good.   We Also Discuss: The Supplement Lies You've Been Told Why Bio-Individuality Changes Everything How to Spot a Scam Supplement The Foundational Stack You Actually Need Muscle, Brain & Bone: The Smart Stack Upgrade Your Brain: Next-Gen Nootropics The New Science of Sleep Support Immunity, Mitochondria & Microbiome Hacks   Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Shawn Wells   Website: www.shawnwells.com Instagram: @shawnwells YouTube: Shawn Wells
What if menopause didn't have to be a challenge, but an opportunity?    In this episode of Extend, I'm joined by Zora Benhamou, host of the Hack My Age podcast, to challenge the common narrative around menopause. Zora shares a refreshing perspective that empowers women to see this stage of life as a chance for reinvention, growth, and better health. We discuss the science behind hormone therapy, the importance of muscle-building and stress management, and how women can navigate menopause without feeling defeated. Together, we dive deep into practical, science-backed insights on how women can not only reduce symptoms but optimize their health for the long run. Zora Benhamou is a gerontologist and health and longevity expert, dedicated to helping women navigate aging confidently. As the host of Hack My Age, she educates listeners on biohacking, menopause, and anti-aging strategies.   We Also Discuss: Podcast Interview on Women's Health Global Attitudes Towards Menopause Optimizing Menopausal Health Through Biohacking Mastering Parasympathetic Balance and Hormone Replacement Post-Surgery Supplement Hacks for Recovery Surgery Gratitude and Recovery Hacks Thank you for our Sponsors: Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah   Learn more about Dr. Shah: Website: https://www.drshah.com/  Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Zora Benhamou:   Website: Hack My Age​ Instagram: @hackmyage​ Facebook: Hack My Age​ YouTube: Hack My Age TikTok: https://tiktok.com/@hackmyage Membership Group: https://hackmyage.com/biohacking-menopause-membership/  Menopause Quiz: https://quiz.tryinteract.com/#/661e9e6786298f2031ac25ba  ​
Brain fog, forgetfulness, and lack of focus are becoming the norm, but they don't have to be. In this episode of Extend, I'm joined by Jim Kwik, a world-renowned brain coach and author of the bestselling book Limitless, to uncover how to unlock your brain's full potential. We dive into the science of neuroplasticity, daily habits that sabotage your memory, and how to reclaim focus in a world of constant distraction. Jim shares actionable tools to improve learning, strengthen cognitive performance, and boost mental energy, without relying on caffeine or willpower. We also explore the impact of gut health, sleep, HRV, and nootropics on brain function, and how to build a sharper, more resilient mind at any age. Jim Kwik is a world-renowned brain coach, best-selling author of Limitless, and expert in memory, focus, and accelerated learning.   Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Jim Kwik: Instagram: @jimkwik​ Facebook: @jimkwikofficial​Log in or sign up to view Twitter: @jimkwik​ YouTube: Jim Kwik
In today's episode of Extend, we're tackling a crucial health issue: high blood pressure. Often called the "silent killer," high blood pressure increases your risk for heart attacks, strokes, kidney disease, and more. But what if you could prevent these risks before they escalate? I'll break down why measuring your blood pressure at home is far more effective than relying on a single doctor's visit. You'll also learn about the SPRINT trial and why keeping your blood pressure at 120/70 can significantly improve long-term health. We'll explore practical steps to manage high blood pressure, including improving your sleep, reducing stress, optimizing metabolic health, and incorporating strength training. Plus, I'll discuss how new medications and emerging technologies like continuous blood pressure monitoring are transforming care. This episode is all about prevention and early intervention—two key elements to living a longer, healthier life. If you've been ignoring your blood pressure, now's the time to take control. Tune in! I Also Discuss:   Understanding High Blood Pressure As A Silent Killer The Importance Of At-home Blood Pressure Monitoring How The Sprint Trial Revolutionized Blood Pressure Management Effective Lifestyle Changes To Control High Blood Pressure Thank you for our Sponsors: Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com    Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah Sources:    SPRINT Studyhttps://www.sprinttrial.org    Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
Ever feel stuck, even when you're doing all the right things? In this episode, Dr. Shah sits down with Dr. Alok Trivedi, also known as Dr. Rewire, to explore how our unresolved traumas, subconscious beliefs, and identity patterns silently shape our health, habits, and happiness. You'll discover how trauma wires into the nervous system, why mindset work often fails without deeper emotional integration, and how behavioral reprogramming can unlock personal and professional breakthroughs. Dr. Trivedi breaks down the neuroscience of change, helping us understand how to stop repeating old cycles and start rewiring for resilience, clarity, and growth. Whether you're navigating stress, burnout, or simply ready to evolve, this episode delivers science-backed insights with real-world tools to shift your life from the inside out. Dr. Alok Trivedi is a leading expert in performance psychology, founder of the Rewire system, and has helped thousands reprogram their minds for lasting transformation. We Also Discuss: How trauma silently influences your behavior, health, and identity Why mindset work alone isn't enough for real transformation The science of "rewiring" your brain to break free from subconscious patterns How emotions get stored in the nervous system—and how to release them Why personalized healing depends on the type of trauma you've experienced Real-world strategies to shift out of survival mode and into aligned action Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Alok Trivedi: Website: https://drrewiretest.com/ Instagram: @dr.rewireLinkedIn: Dr. Alok Trivedi Thank You to Our Sponsors:   TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Books: Wired for Wealth: Unlocking Your Brain for Financial SuccessChasing Success: Lessons in Aligned Performance
With shelves full of flashy promises, it's time to cut through the noise. In this episode, Dr. Shah and Dr. Greg Kelly explore what science actually says about supplements—and what your body truly needs to perform at its best.   You'll learn how nootropics, adaptogens, and probiotics influence brain health, stress resilience, and longevity. Backed by clinical research, Dr. Kelly unpacks the key mechanisms behind compounds that support cognitive performance, neuroplasticity, and the gut-brain connection—revealing how your microbiome plays a central role in mood, immunity, and energy regulation.   Whether you're aiming for sharper focus, better digestion, or long-term health, this episode delivers a practical roadmap to optimize your supplement strategy—minus the hype. Dr. Greg Kelly is a licensed naturopathic physician and leading authority in nootropics and human optimization. He's the Director of Product Development at Neurohacker Collective and author of Shape Shift.   We Also Discuss:    The overwhelming number of supplements on the market How to optimize brain health and performance with the right compounds Enhancing resilience with supplements The link between nootropics and gut health How symbiotics support gut health Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Greg Kelly Instagram: Qualia Life Sciences LinkedIn: Gregory Kelly - Qualia Life Sciences​ Book: Shape Shift Intelligence Solution    Sources: https://www.liebertpub.com/doi/abs/10.1089/acm.2007.7117?journalCode=acm  https://www.tandfonline.com/doi/full/10.1080/10408398.2021.2021137  https://www.drashwame.ie/ashwagandha-journal/ashwagandha-lions-mane/  https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2023.1164676/full https://www.mdpi.com/2072-6643/16/22/3955 Thank You To Our Sponsors:  Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com Timeline: Upgrade your energy from within! Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah
Inflammation drives nearly every chronic disease, yet most people overlook a key player in regulating it: the vagus nerve. This critical nerve connects brain to body, controlling digestion, heart rate, immunity, and recovery. But chronic stress shuts it down, leading to poor vagal tone, dysregulated inflammation, and reduced resilience. In this episode of Extend, I sit down with Dr. Navaz Habib to explore how vagus nerve activation can reduce inflammation and improve healthspan. We dive into practical strategies to improve vagal tone, from breathwork and cold exposure to high-tech biohacking tools. We also unpack how HRV (heart rate variability) can be your secret weapon for tracking nervous system health, and why it's the future of longevity science. Dr. Navaz Habib is a functional medicine practitioner, speaker, and author specializing in nervous system regulation and inflammation. His work empowers people to take control of their health by optimizing vagal tone and HRV. We Also Talk About:   Unlocking Health Through the Vagus Nerve Understanding Chronic Inflammation and Immune Responses Regulating Inflammation Through Vagus Nerve Optimizing Health With Heart Rate Variability Mastering HRV Through Breathwork Exploring Vagus Nerve Health Indicators Exploring Vagus Nerve Stimulation Devices   Thank You to Our Sponsors:   TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Navaz Habib: Instagram: @drnavazhabib​ Facebook: Dr. Navaz Habib​ YouTube: Dr. Navaz Habib​
Heart disease is still the number one cause of death, yet most people don't realize how preventable it actually is. In this solo episode of Extend, I'm kicking off our new series on preventative medicine by breaking down the essential tests and metrics you need to know to protect your heart. I'll walk you through the four key areas I evaluate in every patient—ischemia, blood pressure, electrical function, and cardiac capacity—and explain how you can assess your own risk starting today. You'll also learn about the most underutilized tests in cardiology, including the coronary calcium score, CLEARLY CT angiogram, Holter monitors, and VO2 max. These tools can help you detect heart disease decades before symptoms appear—and long before it's too late. This episode is your roadmap to taking control of your cardiovascular health, starting now. If you're over 40 (or even younger with risk factors), this is a conversation you can't afford to miss.   I Also Discuss:   Preventing Heart Disease for Longevity Advanced Heart Health Screening Options Preventing Heart Disease Through Testing The 4 Hidden Heart Risks You Shouldn't Ignor   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
Most people don't think about their health until something goes wrong—but what if you could catch potential issues before they become a problem? Studies show that up to 70% of serious health conditions are preventable with early detection, yet traditional healthcare often focuses on treating symptoms rather than identifying root causes. Taking a proactive approach to your health could mean adding years to your life—and life to your years. In this episode, I sit down with Andrew Lacy, the founder of Prenuvo, to explore how cutting-edge whole-body MRI technology is changing the game in preventative health. Andrew explains how early detection can help you get ahead of major health issues and why staying informed about your body's internal health is one of the most powerful things you can do for longevity and overall well-being. We'll also dig into metabolic health, inflammation, and why it's never too early to start taking charge of your health. Andrew Lacy is a seasoned entrepreneur with a background in health and technology. Before founding Prenuvo, he created ZapTravel and Tapulous (the creators of Tap Tap Revenge), one of the earliest hits in the App Store. He holds an MBA from Stanford and a Law degree from the University of Melbourne. Now, he's focused on transforming healthcare by shifting the focus from treatment to prevention through advanced imaging technology. We Also Discuss: The Importance of Full Body MRI Early Detection of Cancer With MRI Advances in Cancer Screening Technologies Advancements in Full Body MRI Musculoskeletal Degeneration and Fat Infiltration Biomarkers and Advanced Imaging in Health Assessing Cardiovascular Health With MRI Advancements in Radiology and Preventative Health Future Imaging Advancements With Brain Scan   Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ Nexthealth: NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/   🔗 Links & Resources:   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Andrew Lacy   Website: https://andrewlacy.com/ https://prenuvo.com/ X: https://x.com/andrewlacy
In today's episode, I sat down with Rajeev Kapur, an AI expert and author of AI Made Simple, to explore the rapidly evolving role of AI in medicine. We dive into how AI is enhancing diagnostics, optimizing treatment plans, and helping patients take control of their own health data. We also break down common fears and misconceptions—will AI replace doctors? Can we trust AI-powered medical advice? How can everyday people use AI tools to improve their health outcomes? Rajeev Kapur is a leading voice in AI education and its applications in healthcare. As an author, speaker, and technology strategist, he specializes in making AI accessible and practical for both professionals and the general public. His work focuses on bridging the gap between cutting-edge technology and real-world healthcare solutions. Whether you're a healthcare professional curious about AI's future or someone looking for ways to use AI to optimize your own health, this episode is packed with essential insights. We Also Discuss:  Exploring AI in Healthcare Integration Empowering Healthcare Education With AI Personalized Healthcare Coaching With AI Advancements in Longevity and Wellness AI Enhancing Healthcare Conversations Beginner's Guide to AI Basics   Thank You To Our Sponsors:  Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com Timeline: Upgrade your energy from within! Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Rajeev Kapur  Instagram: therajeevkapurWebsite: https://rajeev.ai/ Book: AI Made Simple
Bone health is often overlooked until a fracture happens—but by then, the damage has already been done. What most people don't realize is that bones are not just structural; they play a critical role in metabolism, hormone regulation, and long-term vitality. In fact, emerging research shows that osteoporosis and bone loss start much earlier than expected, even in people in their 30s and 40s. So how can you build and maintain strong bones that support your health for a lifetime? In this episode, we uncover the hidden endocrine role of bones, how they influence everything from testosterone to brain function, and why strength training is essential—not just for muscle, but for bone density and metabolic health. We also explore the early warning signs of osteoporosis (including in young adults), the overlooked lifestyle factors that accelerate bone loss, and the latest breakthroughs in hormone therapy for skeletal strength. To guide us through the science, I'm joined by Dr. Vonda Wright, an orthopedic surgeon, author, and longevity expert specializing in musculoskeletal health. With decades of experience treating elite athletes, weekend warriors, and aging populations, Dr. Wright is redefining how we think about movement, mobility, and skeletal longevity. If you want to future-proof your bones, prevent fractures, and stay strong well into old age, this episode is packed with insights you won't want to miss. We Also Discuss: (00:00) Doctors Discuss Health, Longevity, and Teaching (09:28) Revolutionizing Healthcare and Education (16:25) The Astonishing Role of Bones (31:06) Functional Movement and Mobility Training (44:05) Optimizing Bone Health Through the Lifespan (58:15) Optimizing Health Through Science and Hormones (01:12:11) Measuring Senescent Cells and Longevity (01:26:30) Anticipation for Upcoming Book Launch   Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ Nexthealth: NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Vonda Wright Website: https://www.drvondawright.com Instagram: https://www.instagram.com/drvondawright Facebook: https://www.facebook.com/DrVondaWright
What if the symptoms you've been chalking up to "normal life"—brain fog, persistent insomnia, chronic fatigue, and the stubborn belly fat—were actually signs of a deeper disconnection from what makes us truly human? In this episode, I sit down with Jeff Krasno, author of "Good Stress: The Health Benefits of Doing Hard Things," to explore the hidden epidemic of disconnection and its profound impact on our health. We dive into why social isolation is as harmful as smoking 15 cigarettes daily, how community might be the #1 factor in longevity according to Harvard's 85-year study, and practical strategies for rebuilding "social fitness" in an increasingly isolated world. Jeff shares his personal journey from successful wellness entrepreneur to burnout victim—running a yoga festival while suffering from insomnia, pre-diabetes, and deep disconnection. His story reveals how the modern lifestyle can lead anyone into what he calls "wealth and hellness" instead of health and wellness. Jeff is the co-founder and CEO of Commune, a masterclass platform for personal and societal well-being. He hosts the Commune podcast, interviewing a wide variety of health experts and luminaries from Andrew Huberman and Marianne Williamson to Matthew McConaughey and Gabor Maté. Jeff pens a personal weekly essay titled "Commusings" that explores spirituality, wellness and culture and is distributed to over one million subscribers every Sunday. Jeff is the author of Good Stress, a collection of wellness protocols that he developed to reverse his diabetes, lose 60 pounds and reclaim his health at age 50.   We Discuss:   (01:00) - Belonging, Community, and Loneliness (14:34) - Social Connection and Introversion (25:53) - Health Crisis in Modern Society (33:22) - Navigating Burnout and Stress Responses Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Jeff Krasno:  Website: https://www.jeffkrasno.com/  Instagram: @jeffkrasno Thank You To Our Sponsors:    Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com Timeline: Upgrade your energy from within! Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah
We often hear about the latest treatments for chronic disease, but what if you could prevent these conditions before they even begin? The truth is, most of the top 10 causes of death are entirely preventable, yet our healthcare system focuses on treating disease rather than stopping it in its tracks. In today's episode of Extend, I'm breaking down the science of preventative medicine, and how you can take control of your health before disease takes control of you. Most chronic diseases don't happen overnight; they develop over years of silent damage. But by understanding early warning signs and risk factors, you can intervene before these conditions ever take hold. We'll explore how cardiovascular disease is the common denominator behind multiple causes of death, including heart disease, stroke, and kidney failure. You'll learn why metabolic dysfunction plays a hidden role in everything from diabetes to Alzheimer's. Plus, we'll discuss why early cancer detection is the #1 factor in survival rates, and how improving your immune health can make all the difference. And beyond chronic disease, I'll dive into something most doctors never talk about… accidental injuries. Falls, car accidents, and drug overdoses are responsible for thousands of preventable deaths each year, but small lifestyle adjustments can dramatically reduce your risk. If you're serious about living longer and better, this episode is a must-listen. Prevention is the key to longevity, let's dive in! I also discuss: Preventative Medicine The 10 Leading Causes of Death and Why They're Preventable The Role of Cardiovascular Health in Chronic Disease Early Cancer Detection: The Key to Survival Preventing Accidents & Chronic Diseases   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
Fasting has been praised as a powerful tool for weight loss, metabolic health, and longevity, but is it always beneficial? The truth is, fasting can either optimize your biology or work against you, depending on how, when, and for how long you do it. Research now suggests that skipping breakfast, a common intermittent fasting practice, is linked to higher cardiovascular risk and increased mortality. At the same time, strategic fasting has been shown to trigger cellular regeneration, reduce inflammation, and even reverse certain disease markers. So, how do you get it right? In this episode, we break down the biggest mistakes people make with fasting, the science of fasting-induced repair mechanisms, and the critical role of refeeding in longevity. We also dive into the controversy around high-protein diets, how different macronutrients impact aging, and why a personalized approach to nutrition is essential for long-term health. To guide us through the latest research, I'm joined by Dr. Valter Longo, a globally recognized expert on longevity and nutrition. As a professor at USC and director of the Longevity Institute, his groundbreaking work on fasting and aging has reshaped how we understand diet and disease prevention. His research led to the development of the Fasting-Mimicking Diet, a clinically tested approach designed to harness the benefits of fasting while maintaining proper nourishment. Let's get into it. We Also Discuss: 01:41 - 03:33 – The Biggest Mistakes People Make with Fasting 07:32 - 08:44 – Personalizing Your Diet for Longevity 18:26 - 20:30 – How Processed Foods & Starches Impact Your Metabolism 25:51 - 26:36 – The Hidden Dangers of Excess Protein 31:54 - 33:47 – The Right Way to Think About Fats 40:22 - 41:49 – How Fasting Triggers Self-Repair Mechanisms 46:39 - 48:32 – Fasting vs. GLP-1 Drugs—What's Better for Metabolic Health? 47:33 - 01:38 – Can Fasting Reverse Biological Age?   Thank You to Our Sponsors:   TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ Nexthealth: NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Valter Longo   Website: https://valterlongo.com/welcome/ Instagram: https://www.instagram.com/prof_valterlongo/ Facebook: https://www.facebook.com/@profvalterlongo/
What if the symptoms you've been chalking up to aging, low energy, brain fog, stubborn belly fat, and lack of motivation, were actually signs of a deeper hormonal imbalance?  The truth is, testosterone levels in men have been plummeting for decades, and it's not just about aging. Environmental toxins, chronic stress, poor sleep, and nutrient deficiencies are creating a perfect storm for hormonal disruption, affecting not only performance but long-term health and longevity. In today's episode, I sat down with Dr. Tracy Gapin, a board-certified urologist and expert in men's health optimization, to break down the science of testosterone, hormone balance, and high-performance living. We dive into why traditional medicine is failing men, how environmental toxins are silently crushing testosterone levels across generations, and the critical role of biomarker testing in personalizing health strategies. Dr. Tracy Gapin is a board-certified urologist with 23 years of clinical experience in men's health, functional medicine, and longevity. As the founder of the Gapin Institute and author of Male 2.0, he specializes in precision health, leveraging genetics, epigenetics, and advanced diagnostics to optimize performance and extend healthspan. We Also Discuss:   00:00 - Introduction to Men's Health and Hormones 02:15 - Significance of Testosterone in Men's Health 05:30 - Limitations of Traditional Healthcare in Addressing Men's Health Issues 08:45 - Understanding Underlying Reasons for Health Concerns 12:00 - Comprehensive Biomarker Testing for Health Optimization 15:20 - Impact of Lifestyle Factors (Nutrition, Stress) on Hormone Levels 18:35 - Effects of Environmental Toxins on Testosterone Levels and Overall Health 22:10 - Distinction Between Total Testosterone and Free Testosterone 25:45 - Relevance of Testosterone for Both Men and Women 29:00 - Various Methods of Testosterone Therapy (Injectable, Topical, Pellets) 32:30 - Management and Necessity of Regular Testing in Hormone Therapy 35:50 - Personalized Approaches to Hormone Therapy Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Tracy Gapin:  Website: https://drtracygapin.com/ https://gapininstitute.com/start-here-gapin/ Instagram: https://www.instagram.com/drtracygapin/   Thank You To Our Sponsors:    Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com Timeline: Upgrade your energy from within! Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah
Have you ever wondered why gut health is at the root of everything, from metabolism and cravings to immunity and even mental clarity? Why do some people struggle with weight gain, energy crashes, and digestive issues despite eating well? And could the rise of GLP-1 medications like Ozempic be a sign that we've been ignoring a natural solution all along? In today's episode of Extend, I'm joined by Colleen Cutcliffe, a microbiome scientist and co-founder of Pendulum, a company leading the way in gut health research. She's here to break down why your microbiome isn't just about digestion, it plays a critical role in weight regulation, blood sugar balance, and even hormone production. We'll explore how your gut bacteria influence GLP-1, the hormone behind popular weight loss drugs, and why restoring your microbiome may be the key to naturally optimizing metabolism, reducing cravings, and improving long-term health. If you've ever dealt with stubborn weight, gut issues, or unexplained fatigue, this episode will give you science-backed strategies to rebuild your gut health, support natural GLP-1 production, and take control of your metabolism, without relying on injections. Colleen Cutcliffe, PhD, is a biochemist and microbiome researcher with over 20 years of experience in biotechnology and life sciences. She is the CEO and co-founder of Pendulum, a company pioneering next-generation probiotics to optimize metabolic and gut health. We Also Discuss: (00:00) What Is the Microbiome & Why It Matters (14:40) How Your Skin & Oral Microbiome Affect Overall Health (33:48) The Gut-GLP-1 Connection: How Your Microbiome Regulates Metabolism (44:24) How Menopause Transforms Your Gut Microbiome (51:05) The Gut-Brain Connection: How Your Microbiome Produces Neurotransmitters (58:02) How an Unhealthy Microbiome Leads to Disease (01:03:51) How to Improve Your Gut Health With Diet & Testing (01:14:32) The Future of Microbiome Science: Supplements & Targeted Probiotics   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Colleen Cutcliffe:   Website: https://pendulumlife.com/ Instagram: https://www.instagram.com/pendulumlifeco/  Instagram: https://www.instagram.com/drcolleencutcliffe/   Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ Nexthealth: NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/
What if everything you've been told about nutrition is only half the story? It's not just about avoiding carbs, counting macros, or following the latest health trend—it's about how food impacts your metabolism, gut, and long-term health on a deeper level. The problem? Most people are stuck in a cycle of restrictive diets, misinformation, and ultra-processed foods that silently sabotage their well-being. In this episode, I sit down with registered dietitian and longevity expert Ella Davar to break down the science of personalized nutrition. We'll explore why gut health is the foundation of everything from digestion to mental clarity, how glucose monitoring can help you optimize your diet, and why ultra-processed foods are doing more damage than you realize. Ella shares her journey from Wall Street to wellness and reveals how a bio-individual, data-driven approach to food can help you feel better, think clearer, and age stronger. Ella Davar is a registered dietitian, gut health expert, and longevity advocate specializing in personalized nutrition. She is also the author of The Guide to a Euterian Diet and the founder of The Gut-Brain Method, a program designed to help people harness the power of food to improve cognitive function, energy levels, and longevity. If you're ready to improve your energy, digestion, and overall health, this episode is for you. Let's get started. We Also Discuss: (00:38) The Problem with Modern Dieting & Why Most People Struggle (04:18) Why Food Is Medicine & How It Transforms Your Health (09:48) Gut Health 101: The Key to Energy, Mood & Metabolism (16:27) How to Use CGM & Stool Testing for Personalized Nutrition (22:13) The Truth About Ultra-Processed Foods & Their Impact on Health (29:02) Bio-Individuality: Why There's No One-Size-Fits-All Diet   Thank You To Our Sponsors:  Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com Timeline: Upgrade your energy from within! Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn More about Ella Davar: Website: https://www.gutbrainmethod.com/ Instagram: https://www.instagram.com/ella.davar/
Sleep isn't just about rest, it's a critical pillar of metabolic health, cognitive function, and longevity. In this solo episode of Extend, I dive deep into the science of sleep routines and circadian rhythms. I share how proper sleep habits are foundational to the new healthcare paradigm focused on vitality rather than disease management. I explain that your sleep routine actually begins the moment you wake up and continues throughout your day, not just before bedtime. I also cover relaxation techniques like four-by-four box breathing and supplements that may help sleep quality, though I typically avoid recommending melatonin except for jet lag. Additionally, I address the common issue of nighttime urination disruptions and offer strategies for returning to sleep if you wake up in the middle of the night, including breathwork and non-sleep deep rest protocols. By implementing these evidence-based techniques consistently, you can transform your sleep quality and overall health. If you're struggling with falling asleep, waking up groggy, or insufficient deep sleep, this episode provides a concrete, step-by-step strategy to build a powerful sleep routine that optimizes your health, longevity, and daily performance. I Discuss: 03:40 The genetic factors that determine your natural sleep-wake tendencies 05:54 Morning routine strategies to optimize your circadian rhythm 07:37 Evening wind-down practices 09:09 Lifestyle factors affecting sleep quality 11:34 Supplements for sleep and managing common sleep disruptions 13:14 Breathwork and journaling   Studies Cited: https://academic.oup.com/sleep/article/40/2/zsw048/2662182 https://pubmed.ncbi.nlm.nih.gov/33054339/ Links: https://sleepdoctor.com/sleep-quizzes/chronotype-quiz   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
Have you ever felt like mental health care is stuck in the past? Why are rates of depression, anxiety, and even conditions like autism skyrocketing in today's world? And why does traditional treatment often fall short? Spoiler: the answer lies deeper than just brain chemistry… it's all about your metabolic health. In this week's episode of Extend, I'm joined by Dr. Chris Palmer, a psychiatrist and author of Brain Energy. Together, we're unraveling the powerful connection between your metabolic health and your brain, exploring how poor nutrition, environmental toxins, and lifestyle choices are driving the modern mental health epidemic. But this isn't just a conversation about problems, it's about solutions. Dr. Palmer shares groundbreaking insights into how addressing metabolic dysfunction can lead to dramatic recoveries for people with conditions once thought untreatable, like schizophrenia, bipolar disorder, and severe depression. Dr. Chris Palmer is a Harvard-trained psychiatrist, researcher, and the author of Brain Energy, a groundbreaking book that challenges conventional views on mental health.His work integrates cutting-edge neuroscience with practical, science-backed strategies to heal the brain through nutrition, lifestyle, and metabolic therapies.  If you're ready to transform the way you think about mental health and learn actionable steps to heal from the inside out, this episode will give you the hope and tools you need. Let's dive in! We Also Discuss: (00:08) Mental Health Epidemic and Root Causes (16:00) Metabolic Health in Mental Wellness (33:38) Metabolic Health and Neurodevelopmental Disorders (44:46) Holistic Approach to Mental Health (59:26) Lifestyle and Metabolic Health Strategies (01:13:16) Personal Stories of Dietary Transformation (01:24:03) The Power of Metabolic Health   Thank You to Our Sponsors:   TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ Nexthealth: NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Chris Palmer: Website:  https://www.chrispalmermd.com/ Instagram: https://www.instagram.com/chrispalmermd
What if the key to peak performance and longevity isn't just in your workouts, diet, or sleep, but in how well your body handles stress? Optimizing your health isn't just about the latest supplements or fitness trends, it's about understanding your nervous system, heart rate variability (HRV), and how small daily habits shape your resilience over time. Most people try to eliminate stress, but the real goal is building the ability to recover faster and adapt better. In this episode, I sit down with Salim Najjar, an HRV expert and biohacker who took his health to the next level by learning how to regulate his nervous system. We break down why stress is a signal, not a problem, how HRV can predict when your body needs rest before you even feel it, and the most effective ways to improve recovery, sleep, and overall well-being. Salim is a biohacker, entrepreneur, and founder of Sound Beverages, a company focused on functional health drinks. After years of pushing his body with extreme training and biohacking, he discovered the missing piece: HRV as a measure of how well the body adapts to stress. Now, he teaches others how to improve their HRV, manage stress more effectively, and use data to optimize performance and longevity. If you're looking for real, actionable strategies to train your nervous system, boost recovery, and perform at your best, this episode is for you! Let's dive in. We Also Discuss: 00:00 - 07:45 — Why HRV Is the Most Important Health Metric 07:46 - 14:30 — The Connection Between Stress, Emotions, and HRV 14:31 - 19:00 — Science-Backed Hacks to Improve HRV 19:01 - 24:30 — The Biggest Mistakes People Make When Trying to Boost HRV 24:31 - 27:30 — Tracking HRV: The Best Wearables and Tools for Accurate Data 27:31 - 30:00 — How to Use HRV Data for Better Performance & Longevity   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn More about Salim Najjar: If you are ready to unlock your body's innate wisdom and tap into the transformative power of HRV, join Salim's mailing list for exclusive early access to his HRV Mastery program below: https://mailchi.mp/thathrvguy/br64h15j2n  Instagram: @thathrvguy Website: www.thathrvguy.com
If you're struggling to fall asleep, waking up in the middle of the night, or feeling groggy in the morning, the problem might not be you—it might be your sleep environment. Most people don't realize just how much their bedroom setup impacts sleep quality. In this episode of Xtend, I'm breaking down exactly how you can optimize your space to promote deep, restorative sleep. Your bedroom should mimic the ideal sleep conditions humans evolved with—a cool, dark, and quiet environment. That's why in today's episode of Extend, I'll be sharing 10 key changes you can make to transform your sleep environment. Your bedroom should be your sanctuary for sleep, and small changes can lead to huge benefits in energy, focus, and long-term health. Tune in as I share practical, science-backed strategies to optimize your sleep setup so you can wake up truly restored. What's Discussed:  Eliminating light exposure (hint: blackout curtains and sleep masks are game-changers) Removing clocks and charging your phone outside the bedroom Cooling your room to the ideal sleep temperature Decluttering for a stress-free sleep space Using white noise or earplugs to block out disruptions Investing in a supportive mattress and pillow Choosing the right sleepwear and sleep position for optimal rest Addressing snoring and potential sleep apnea risks Creating separate sleep spaces for pets—and maybe even your partner Using sleep tracking tools to measure improvements Learn more about Dr. Shah: Instagram: https://www.instagram.com/darshanshahmd/ Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Products Mentioned: Eight Sleep Cooling Matress Pad: https://www.eightsleep.com/ The Snore Lab App: https://www.snorelab.com/ The Smart Nova Pillow: https://www.smartnora.com/
Do you ever feel like your wellness journey is missing something? We often focus on physical health—what we eat, how we exercise—but overlook the powerful role our mind plays in driving true transformation. From reducing stress to optimizing focus, your thoughts and beliefs shape every aspect of your well-being.  The key to lasting change may be closer than you think: it starts in your mind… What if you could reverse your biological age just by changing your mindset? In this episode, Vishen Lakhiani joins me for a powerful conversation about the mind-body connection. We break down how practices like meditation, breathwork, and visualization can unlock your full potential. You'll learn how these tools improve everything from sleep to energy levels and even cellular health, helping you stay vibrant and strong for years to come. We also discuss the groundbreaking work in personal transformation, including the science behind intuition, the six-phase meditation, and how hyper-personalized wellness is changing the game.  Vishen Lakhiani is a bestselling author, founder of Mindvalley, and a pioneer in personal transformation and wellness. With a mission to elevate human potential, he's revolutionized how millions approach meditation, intuition, and longevity practices. His latest innovations combine science and spirituality to create accessible, life-changing tools for everyone. This episode will inspire you to rethink your approach to health—and show you how to use your mind to future-proof your body. Don't miss this! We Also Discuss: (00:02) Personal Development and Wellness Discussion (12:10) Exploring the Power of Intuition (22:06) The Power of Mind-Body Healing (26:27) The Power of Meditation and Mindfulness (39:45) The Code of the Extraordinary Mind (48:09) Personalized Health and Wellness Practices (53:31) Mindfulness, Meditation, Fitness, and Supplementation (58:48) Mastering the Mind for Brain Health   Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Vishen Lakhiani Website: https://www.mindvalley.com/ Instagram: https://www.instagram.com/vishen/
Most people think longevity is about expensive treatments, cutting-edge technology, or the latest supplements. But what if the real key to aging well comes down to something much simpler, understanding your body, making informed choices, and building habits that last?  Healthspan matters more than lifespan, and the small, consistent actions you take today will determine how you feel decades from now. In this episode, I sit down with Julie Gibson Clark, a longevity researcher and biohacker who took her health into her own hands.  We explore how the modern medical system is primarily structured to manage symptoms rather than address root causes, focusing on reactive treatments like pharmaceuticals instead of proactive strategies that could prevent disease in the first place.  We also break down the biochemical impact of food on metabolic health, including how nutrients influence mitochondrial function, inflammation, and insulin sensitivity at a cellular level. Finally, we dive into the science of biological age tracking, how DNA methylation and epigenetic markers reveal the true state of aging, and what you can do to slow (or even reverse) the aging process. Julie is proof that anyone can take control of their health with the right strategies. Her journey led her to become one of the top-ranked individuals on the global longevity leaderboard, showing that aging well isn't about luck or genetics, it's about knowledge, consistency, and the willingness to experiment.  We Also Discuss: (00:29 - 01:52) — Why real-life longevity journeys matter (08:00 - 10:00) — The limitations of Western medicine in long-term health (16:16 - 19:31) — How genetics influence aging and why lifestyle changes are key (24:14 - 27:43) — The importance of self-education in health and longevity (30:15 - 34:28) — The "wellness wheel" approach to optimizing health (39:53 - 44:28) — Biomarkers and tracking real progress in aging Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn More about Julie Gibson Clark Website: https://www.juliegibsonclark.com/ Instagram: juliegibsonclark
Sleep isn't just about rest, it's a critical pillar of metabolic health, cognitive function, and longevity. Poor sleep quality is linked to increased risks of cardiovascular disease, diabetes, neurodegeneration, and even cancer. In this episode of Extend, I break down how tracking your sleep can uncover hidden disorders, optimize recovery, and improve long-term health. I'll share my personal struggle with undiagnosed sleep apnea and how data-driven sleep optimization completely transformed my energy, metabolism, and resilience. We'll discuss the key warning signs of sleep disorders, including excessive daytime fatigue, morning headaches, and snoring, and why conditions like sleep apnea go undetected for years. Understanding sleep quality requires more than just tracking hours slept. I'll explain the most critical sleep metrics, sleep efficiency, deep and REM sleep cycles, HRV (Heart Rate Variability), and nighttime oxygen levels, and how they reflect nervous system balance and recovery. We'll also explore cutting-edge sleep tracking tools like Oura, Whoop, and advanced mattress sensors, plus at-home sleep studies for diagnosing apnea risk. If you're serious about health and longevity, sleep tracking is non-negotiable… Tune in to learn how to upgrade your sleep and unlock peak performance! I Also Discuss: (00:19) Unlocking Better Health Through Sleep Monitoring (05:23) Snoring vs. Sleep Apnea: How to Identify the Warning Signs (07:27) The Best Sleep Trackers and What Your Data Actually Means (09:09) Key Sleep Metrics: Sleep Stages, HRV, and Sleep Efficiency Explained (11:39) Unlocking Your Highest Sleep Potential   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
Most of us think hitting the gym a few times a week is enough—but what about the other 23 hours of your day? Your daily habits could be silently limiting your mobility and longevity without you even realizing it. In this episode of Extend, I sit down with Kelly and Juliet Starrett, bestselling authors of Built to Move and pioneers in the world of mobility and movement. We break down why small, everyday actions—like how you stand, sit, and breathe—are more important for your health than chasing big fitness milestones. You'll learn why mobility is a critical biomarker of longevity, how walking is your ultimate low-tech health hack, and why simple assessments (like the sit-and-rise test) can reveal more about your future health than you might think. The Starretts also share actionable tips to counteract "tech neck," build joint resilience, and integrate mobility work into your daily life without it feeling like a chore. Kelly and Juliet Starrett are the co-founders of The Ready State and are globally recognized for their work in improving human performance and movement. Their latest book, Built to Move, is a guide to sustainable fitness and pain-free living—no matter your age or fitness level. If you're ready to rethink what it means to stay active and build a body that thrives for decades, this episode is for you. We Also Discuss: (00:02) The Importance of Mobility and Movement (12:19) Reviving Movement Through Playful Context (27:27) Transforming Movement Culture in Education (38:15) The Importance of Walking for Health (01:00:22) Understanding Movement Deficits and Solutions (01:21:51) The Importance of Breathing Mechanics (01:34:00) Creating a Daily Mobility Routine (01:48:18) Incorporating Balance and Rest for Health Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Kelly and Juliet Starrett :    Website: https://thereadystate.com/  Instagram: https://www.instagram.com/julietstarrett/?hl=en  Instagram: https://www.instagram.com/thereadystate/?hl=en    Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/
How often do you find yourself struggling with cravings, feeling like your hunger is out of control, or wondering why weight loss feels impossible? The truth is, your gut is running the show, specifically, a powerful hormone called GLP-1 that regulates appetite, metabolism, and even inflammation. And the secret to boosting it naturally? Bitterness. In this episode of Extend, I sit down with Dr. Ed Walker, a leading researcher in translational medicine, to break down how bitter compounds, used for centuries in traditional medicine, can help regulate hunger, control glucose levels, and support long-term weight management.  Together we'll explore the groundbreaking science behind gut hormone therapies, the connection between GLP-1 and cognitive performance, and why modern diets are disrupting our natural appetite signals. If you're looking for sustainable, science-backed ways to improve your metabolism, curb cravings, and optimize your health, without relying on extreme diets or pharmaceuticals, this episode is for you! Dr. Ed Walker is a PhD researcher at the New Zealand Institute of Plant and Food Research, where he specializes in using plant-based compounds for chronic disease prevention. His work led to the discovery of Amarasate, a natural dietary supplement designed to enhance appetite regulation and metabolic health.   We Also Discuss: (00:00 - 09:44) Bitterness & Appetite Regulation (24:57 - 38:18) Boosting GLP-1 Naturally (44:05 - 50:19) Discovering & Testing GLP-1 Triggers (50:19 - 59:40) Amarasate: A Natural GLP-1 Booster Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn More about Dr. Ed Walker Website: https://www.calocurb.com/ Instagram: @calocurb
You hit the gym, push your limits, and stay consistent, but if you're skipping recovery, you're actually holding yourself back. Overtraining doesn't just slow muscle growth; it ramps up inflammation, messes with your metabolism, and puts unnecessary stress on your heart.  In today's episode of Extend, I'm breaking down why recovery is the missing piece in your fitness routine. We'll cover how overtraining wrecks your hormones, metabolism, and nervous system (and how to fix it), the science-backed "sweet spot" for exercise frequency that maximizes gains without burnout, seven next-level recovery strategies, like breathwork, sauna therapy, and sleep tracking, to speed up muscle repair and prevent injury, and why tracking HRV (Heart Rate Variability) and HRR (Heart Rate Recovery) can help you gauge whether you're actually recovering or just digging yourself into a hole.  If you're constantly sore, exhausted, or stuck in a plateau, this episode is for you! More workouts aren't the answer, better recovery is. Tune in now to level up your training, recover faster, and stay strong for life. I also discuss: (00:03) Optimizing Fitness Recovery Protocols (04:56) The Science of Overtraining & Performance Plateaus (07:19) Cold Plunges, Sauna & Advanced Recovery Hacks (10:15) Maximizing Fitness Recovery Strategies (00:03) Optimizing Fitness Recovery Protocols (10:15) Maximizing Fitness Recovery Strategies Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
How many nights have you told yourself you'll catch up on sleep later? You push through exhaustion, thinking it's just part of life. But here's the truth: chronic sleep deprivation isn't just making you tired—it's rewiring your brain, disrupting your hormones, and holding you back from living your best life. In this episode of Extend, I sit down with sleep expert Dr. Matt Walker to dive into why sleep is the ultimate game changer for your health. We unpack how poor sleep impacts everything from your memory to your metabolism and share science-backed tips to improve your sleep quality without overhauling your entire routine. If you're ready to stop running on empty and start waking up energized and focused, this conversation is for you. It's not about perfection—it's about making small changes that lead to big transformations.  Dr. Matt Walker is a renowned neuroscientist and sleep expert dedicated to unraveling the mysteries of sleep and its profound impact on mental and physical health. As a bestselling author and host of The Matt Walker Podcast, he's known for making complex science accessible and inspiring people to prioritize rest.    We Also Discuss: (00:00) The Importance of Good Sleep (12:33) Optimizing Sleep With Technology (25:08) The Incredible Impact of Sleep (40:49) Understanding the Impact of Caffeine (45:32) The Truth About Coffee and Alcohol (57:21) CBD and THC for Sleep (01:09:04) Detecting and Treating Sleep Apnea (01:22:16) Improving Sleep Through Environment and Routine (01:36:15) Fostering Innovation in Sleep Science Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn More about Matt Walker:   Website: https://www.sleepdiplomat.com/  Instagram: https://www.instagram.com/drmattwalker
What's the point of living longer if you're stiff, in pain, or struggling to stay independent? Mobility isn't just about stretching, it's about keeping your joints fluid, your muscles strong, and your balance sharp so you can move with ease at any age. In today's episode of Extend, I'm breaking down why mobility is the most overlooked pillar of longevity and how you can start improving yours right now. We'll cover why mobility declines with age (and how to stop it), the five simple at-home tests that reveal how well your body moves, and how sitting too much is silently wrecking your joints and metabolism. I'll also explain why exercise snacks, quick bursts of movement, can make a huge difference, and why traditional workouts aren't enough if you want to stay agile for life. Plus, I'll share my personal mobility routine, including the one-minute test I do every morning and the simple habit—yes, even brushing your teeth—that can help prevent falls, injuries, and stiffness as you age. Your mobility is 100% trainable, and it's never too late to start. Tune in now and learn how to future-proof your movement for decades to come! I also discuss: (00:21) - Why Mobility Is the Missing Piece in Longevity (05:44) - 5 Simple Tests to Measure Your Mobility (10:36) - How Sitting Too Much Wrecks Your Joints & Balance (16:16) - The Key to Maintaining Mobility for Life Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
How often do you reach for a sugary snack, telling yourself it's just a small indulgence? Or justify skipping your morning walk because you're "too busy"? Here's the truth: your daily habits are either fueling your longevity or quietly sabotaging it. In this episode of Extend, I sit down with Dr. David Perlmutter, a neurologist and five-time New York Times bestselling author known for his groundbreaking work on brain health, inflammation, and metabolic resilience. We dig deep into the connection between blood sugar, brain aging, and chronic disease—and how small, intentional lifestyle changes can make a massive difference in your long-term vitality. You'll learn how excess glucose can erode your cognitive function and why uric acid—a molecule most of us ignore—may be the key to unlocking better metabolic health. We also share practical tips to curb cravings, improve your sleep, and enhance your focus by rebalancing your diet and mindset. Dr. David Perlmutter is a board-certified neurologist, researcher, and advocate for lifestyle interventions that promote cognitive health and resilience. He is the author of bestselling books like Grain Brain and Drop Acid, and he continues to inspire millions with his work on the gut-brain connection.   We Also Discuss: (00:00) Connecting Through Conversation and Brain Health Foundations (04:40) Evolutionary Biology's Role in Brain Health (14:21) Neurology Meets Functional Medicine (25:52) Metabolic Health and Its Impact on Brain Wellness (41:28) The Gut-Brain Connection Explained (56:09) Understanding Brain Disease Through Metabolic Health (01:03:34) Exercise as a Pillar for Brain Health (01:23:23) Nutrition, Lifestyle, and the Future of Brain Care Thank You to Our Sponsors:  TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. David Perlmutter:   Website: https://drperlmutter.com/  Instagram: https://www.instagram.com/davidperlmutter
Title: Dr. Mindy Pelz: The Metabolic Reset Every Woman Needs Your hormones deserve better care—and you do too. So many women feel stuck when it comes to their health—frustrated by unexplained weight gain, unpredictable mood swings, and low energy that no diet or workout seems to fix. The truth is, our healthcare system was built around research that overlooked the female body's complexity. But the great news? There's a way to support your body that works with your biology, not against it. In today's episode of Extend, I'm diving into how you can break free from metabolic imbalances and reclaim your energy with the right strategies for fasting, nutrition, and movement. You'll learn why women experience hormonal chaos during perimenopause and menopause—and how understanding your body's natural rhythm can make all the difference. I'll also uncover the truth about hidden disruptors in your food and environment, like obesogens and toxins, and how they affect your ability to lose weight and stay healthy. Plus, I'll share game-changing insights on building strength, improving bone health, and balancing your hormones through strategic lifestyle changes. Joining me is Dr. Mindy Pelz, a pioneer in women's health and the bestselling author of Eat Like a Girl. Dr. Mindy's groundbreaking work has empowered thousands of women to embrace fasting, rethink their nutrition, and overcome hormonal imbalances. As the host of The Resetter Podcast, she's built a global community dedicated to helping women live vibrant, resilient lives. This conversation will open your eyes to what's possible when you tune into your body's innate intelligence—you won't want to miss it! We Also Discuss: (00:00) Women's Health Disparities in Medicine (14:06) Medical Paradigm Shift Towards Individualized Care (21:28) Exploring Fasting and Metabolic Health (33:00) The Truth About Obesogens and Toxins (45:00) The Power of Strength Training and Movement (01:12:00) Reclaiming Balance: Key Lifestyle Shifts for Hormonal Health   Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Mindy Pelz   Website: https://drmindypelz.com/ Instagram: https://www.instagram.com/dr.mindypelz
In today's episode of Extend, I'm diving into one of the most powerful and underutilized tools for your health and longevity: strength training. Whether you're a gym regular or just getting started, this episode will break down the science and practical strategies you need to transform your fitness routine. Together, we'll explore the four essential pillars of strength training: building and preserving muscle as you age, how your muscles directly impact your metabolism, the surprising role of muscles as an endocrine organ, and how to create an effective, sustainable routine that fits your lifestyle. From understanding the difference between slow and fast-twitch muscle fibers to how myokines impact everything from brain health to inflammation, this episode is packed with game-changing insights. I'm also sharing actionable tips for optimizing your workouts, from training to failure for muscle growth to recovery techniques like proper sleep, protein intake, and using saunas post-workout. Whether you're 20 or 70, it's never too late to reap the life-extending benefits of strength training. Ready to take your fitness to the next level? Tune in ! I also discuss: (00:12) Why Strength Training is the Ultimate Longevity Tool (03:14) The Truth About Muscle Loss and Aging (06:35) How Strength Training Transforms Metabolic Health (17:38) Strength Training: The Key to Consistency and Longevity   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
Feeling stuck with your health? Maybe you're doing all the right things—or at least you think you are—but you're still not seeing the results you want. It's frustrating, right? But here's the thing: modern life is working against you. Chronic stress, hidden toxins in your environment, and mixed messages about what actually works—it's no wonder so many of us feel lost when it comes to wellness. In today's episode of Extend with Dr. Shah, I'm sitting down with Mona Sharma—nutritionist, wellness expert, and someone who truly gets what it takes to turn things around. We're diving into the real reasons you might not be feeling your best, from the role of your gut health to how stress affects your body more than you realize. We also share simple, actionable ways to detox your life—without feeling overwhelmed—and how to build daily habits that stick, so you can finally feel like the best version of yourself. Mona Sharma is a leading voice in the wellness space, blending her background in integrative nutrition with her expertise in mindfulness and Ayurveda. Mona's worked with top athletes, A-list celebrities, and people just like you to rebuild their health from the inside out. If you're ready to break free from the cycle of exhaustion, stress, and frustration, you're going to love this conversation. Let's jump in!    We Also Discuss: (00:00) Podcast Launch Strategy and Personal Journey (08:43) Exploring Health, Vibrational Shifts (17:19) Navigating Wellness (28:02) Optimizing Digestion and Reducing Toxins (39:52) Detoxifying Your Environment for Health (52:35) Embracing Emotional Health and Wellness (55:53) Creating Daily Rituals for Optimal Health (01:29:24) Foundations of Everyday Health Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Mona Sharma: Website: www.monasharma.com Instagram: @monasharma
In this solo episode of Extend, I'm breaking down the science behind sustainable fitness progress and goal-setting so you can finally make those health resolutions stick. From understanding your baseline fitness level with key assessments to the power of setting small, realistic goals, I'm guiding you step-by-step through the tools that build long-term consistency. We'll talk about everything from DEXA scans for precise body composition analysis to why grip strength and lower body power are vital indicators of longevity. I also share actionable strategies to keep you motivated, avoid plateaus, and make progress checks work for you—not against you. Whether you're starting fresh or trying to push past a plateau, you'll walk away with a personalized blueprint for success. Ready to upgrade your fitness journey? Tune in for proven insights you can start applying today!   I Also Discuss:   (00:06) Testing Fitness Progress and Goals   (03:50) Measuring and Improving Physical Fitness   (10:17) Comprehensive Strength and Fitness Testing   (22:00) Motivating Fitness Testing and Goal Setting   Resources mentioned: PDF - Strength, Mobility, and Cardiorespiratory Fitness Assessment   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
Your brain is your most powerful asset—so why do so many of us let it decline without a fight? Cognitive decline, brain fog, and even Alzheimer's don't just "happen." They're the result of decades of small decisions, stress, and overlooked habits. The good news? You have the ability to take control. In this episode of Extend, I sit down with Louisa Nicola, neurophysiologist and human performance coach, to uncover the science behind optimal brain health and the simple habits that can keep your mind sharp and resilient.  We talk about the role of exercise (and why your muscles are key to brain health), how sleep works like a "cleaning system" for your brain, and why inflammation is the root of so many cognitive issues. Louisa Nicola is a neurophysiologist and founder of NeuroAthletics, specializing in brain optimization and cognitive performance. With a background as an elite triathlete, she focuses on using exercise and science-backed protocols to prevent neurodegenerative diseases. Louisa works with top executives, athletes, and high achievers worldwide. We Also Discuss: (00:00) Neurophysiology and the Foundations of Brain Health (22:11) The Role of Nutrition in Brain Optimization (34:05) How Aerobic and Resistance Training Transform Brain Function (50:01) Deep Sleep: The Brain's Most Powerful Recovery Tool (56:59) Understanding Alzheimer's Disease and How to Prevent It Resources mentioned: The Levine Protocol Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Louisa Nicola: Website: https://www.neuroathletics.com.au/  Instagram: https://www.instagram.com/louisanicola_
Have you ever wondered if hitting the gym is enough to offset hours of sitting at your desk? In this episode of Extend, I take a closer look at the silent yet dangerous effects of sedentary behavior—and why it could be one of the most overlooked threats to your long-term health. From the link between prolonged sitting and chronic diseases like heart disease and Alzheimer's to the surprising impact it has on your metabolic health, I'm breaking down the science behind why movement throughout the day matters more than you think. I also share strategies to help you stay active, including simple exercise "snacks" that don't require a gym membership, the truth about standing desks, and why a daily walk after meals can drastically improve your overall well-being. If you're ready to level up your health by eliminating sedentary habits, this episode is full of actionable tips you can implement today. Tune in!   We Also Discuss:   (00:18) Understanding Sedentary Behavior (04:15) What Counts as Sedentary? (08:52) The Power of "Exercise Snacks" (12:43) Combatting Sedentary Behavior Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
Do you know the #1 preventable cause of death worldwide? It's high blood pressure—a condition that half of the population doesn't even know they have. Mismanaged and misunderstood, this "silent killer" leads to heart attacks, strokes, kidney failure, and dementia. Yet, most people rely on outdated tools like cuffs that deliver inconsistent readings or aren't used correctly at all. In this episode of Extend, I sit down with Dr. Jay Shah, a cardiologist and blood pressure expert to tackle the barriers holding us back from controlling hypertension effectively. Together, we explore how innovative tools are not just changing how we measure blood pressure, but how we approach prevention, treatment, and even early detection. We also talk about topics like metabolic syndrome, the connection between stress and hypertension, and how small lifestyle changes can yield big results.  Dr. Jay Shah is a practicing cardiologist with over 15 years of experience, including tenure at the Mayo Clinic and Mass General. Now the Chief Medical Officer at Aktiia, he is leading the charge in developing wearable health technologies that aim to transform global blood pressure management. We Also Discuss: (00:00) Health Presentation at Harvard Business School (18:14) Understanding Metabolic Syndrome and Its Connection to Blood Pressure (32:52) Lifestyle Factors and Their Impact on Hypertension (40:40) Stress, Sleep, and Their Role in Blood Pressure Management (48:51) Identification and Management of Resistant Hypertension (01:00:15) Strategic Use of Blood Pressure Medications (01:06:16) The Evolution of Continuous Blood Pressure Monitoring Technology (01:12:28) Future Innovations in Blood Pressure Monitoring and Predictive Health   Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/  IFIT: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Jay Shah:   Website: https://aktiia.com Instagram: https://www.instagram.com/aktiiaglobal/
Are you stuck in a relentless cycle of stress that's draining your energy and joy? Burnout isn't just about feeling tired—it's a chronic state that rewires your body and mind, often without you realizing it. In this episode of Extend, I sit down with Dr. Rangan Chatterjee, a trailblazer in functional medicine and best-selling author, to explore how modern life has hijacked our stress response systems. Together, we unpack why today's constant pressures—from overflowing inboxes to endless social media scrolling—are leaving so many of us overwhelmed and disconnected from our true selves. We dive into Dr. Chatterjee powerful strategies for addressing burnout, including the surprising benefits of micro-habits like a 5-minute workout or a tea ritual. We also discuss the profound impact of aligning your daily actions with your core values and how these practices can transform your well-being. Dr. Rangan Chatterjee is a globally recognized pioneer in functional medicine, the author of six best-selling books, including Make Change Last, and the host of the widely celebrated Feel Better, Live More podcast, which has over 250 million downloads. With over two decades of clinical experience, he has empowered millions to take control of their health through practical, sustainable lifestyle changes.   We Also Discuss: (00:02) Functional Medicine Foundations (11:55) Understanding and Combating Burnout (23:11) Creating Sustainable Health Routines (50:37) The Power of Intentional Living (01:47:14) Personalized Health and Data (01:06:46) Transforming Health Through Self-Discovery (02:25:37) Rethinking Healthcare and Advocacy (02:33:23) Revolutionizing Health With Functional Medicine   Thank You to Our Sponsors: Timeline: If you are looking for a boost in a cellular level, Timeline is the secret to unlocking your mitochondria's whole potential. Go to: https://www.timeline.com/ TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Rangan Chatterjee: Website: https://drchatterjee.com/ Instagram: https://www.instagram.com/drchatterjee
Have you ever felt overwhelmed by the endless options in the supplement aisle? In this episode of Extend, I take a closer look at why so many people struggle to make sense of supplementation—and what you can do to make smarter, science-backed decisions. From the declining nutrient density in modern diets to the role of supplements in addressing deficiencies and optimizing health, I'm breaking it all down. I also reveal the foundational supplements everyone should consider (like Vitamin D, Omega-3s, and Magnesium), the cutting-edge advancements in supplementation, and why personalized protocols are the future of health optimization. If you're ready to cut through the confusion and build a supplement routine that truly works for you, this episode is packed with actionable insights you don't want to miss. Tune in to discover how supplements can bridge the gap between where you are and where you want to be.   We Also Discuss:   (00:38) Introduction: The bell-shaped curve of supplementation (02:33) Why modern diets fall short in essential nutrients (03:59) Foundational supplements everyone should consider (06:46) Advanced supplements for cognitive and metabolic health (11:18) Quality control: How to choose safe, effective supplements Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Thank You to Our Sponsor: IFIT: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/
Have you ever wondered if memory loss or cognitive decline is inevitable as we age? What if I told you it's not—and that, with the right strategies, you can even reverse early signs of neurodegeneration? In this episode of Extend with Dr. Darshan Shah, I sit down with my friend and esteemed colleague, Dr. Dale Bredesen, a pioneer in brain health and the author of The End of Alzheimer's. Dr. Bredesen has completely changed the way I see cognitive decline, and today, we're sharing how cutting-edge science is making Alzheimer's a preventable—and even reversible—condition. Together, we explore some of the most exciting advancements in brain health, from blood tests that predict neurodegenerative diseases years before symptoms appear to the role of inflammation, toxins, and even oral health in driving cognitive decline. We also dive into the power of personalized medicine, showing how addressing root causes can lead to profound recovery. You'll hear inspiring stories of patients who were told they had no hope, only to reclaim their lives through Dr. Bredesen's groundbreaking protocols. If you want to optimize your longevity, this is an episode you won't want to miss. We Also Discuss: (00:02) Advances in Brain Health (07:58) Neural Systems and Disease Progression (13:09) Inflammation, Immune Response, and Neurodegeneration (28:07) Brain Health Through Sleep and Toxins (37:17) Early Detection and Prevention Strategies (48:38) Brain Health Advancements and Technologies (57:39) Aging and Brain Health Optimization (01:05:13) Embracing Life After Retirement Graduation (01:14:12) New Books in Alzheimer's Treatment   Thank You to Our Sponsors: Timeline: If you are looking for a boost in a cellular level, Timeline is the secret to unlocking your mitochondria's whole potential. Go to: https://www.timeline.com/  TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/  IFIT: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Dr. Dale Bredesen   Instagram: drdalebredesenPreCODE and ReCODE: https://www.apollohealthco.com/solutions/
Are you trapped in the cycle of endless dieting and calorie counting? For years, we've been told that weight loss is as simple as "calories in, calories out," but if that's true, why do so many of us still struggle? What if the problem isn't just the numbers, but how we think about them? In this episode of theExtend podcast, I take a closer look at why the traditional approach to calorie control fails—and what you can do instead. From the science behind metabolic rate to the surprising impact of ultra-processed foods on your hunger and hormones, I'm going to break down the three key levers for weight management: calorie restriction, dietary restriction, and time-restricted eating. I also reveal why most diets are destined to fail and how small, sustainable changes can transform not just your weight, but your overall health and energy levels. If you're ready to break free from ineffective methods and embrace a smarter approach, this episode is packed with insights you don't want to miss.  Tune in to discover how you can not just lose weight but feel better in your own skin. We Also Discuss:   (01:51-02:58) Not All Calories Are Created Equal (03:31-04:20) The Japanese Secret to Mindful Eating (06:50-07:28) Where Your Calories Go: Total Energy Expenditure (08:58-09:38) Why Diets Fail 90% of the Time (10:22-11:37) Time-Restricted Eating: Is Fasting for You?   Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/   Learn more about Dr. Shah:   Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
Ever find yourself putting in the time at the gym, only to feel like you're barely moving the needle? Or notice that staying in shape seems to get tougher every year? Here's the thing: muscle health is the backbone of your metabolism, strength, and long-term vitality, but it's often the missing link in most people's routines. In this episode, I'm thrilled to sit down with JJ Virgin. Together, we dive into why muscle matters for more than just strength, how to use high-intensity interval training to hit your fitness goals faster, and practical hacks for optimizing your protein intake—no more wasting time on ineffective routines. JJ Virgin is a leading voice in health and fitness, a best-selling author, and a nutrition and exercise expert. With over three decades of experience, she is dedicated to helping people maximize longevity and metabolic health through science-based, personalized strategies. As a pioneer in the field of powerful aging and fitness for women, JJ blends science and practical advice to promote a strong, active approach to aging. ➡️ If you're ready to understand how to work with your body's natural strengths instead of fighting against it, this is the episode for you. Listen to the full episode of Extended with Dr. Shah for more insights! We Also Discuss: (00:00) Expert Insights on Fitness and Nutrition (04:07) Strength Training for Longevity (28:45) Building Muscle and Custom Training (49:18) Travel-Friendly Workout Tips (01:01:44) Nutrition Strategies for Muscle Growth (01:36:26) Hormone Health in Menopause Thank You to Our Sponsors: Timeline: If you are looking for a boost in a cellular level, Timeline is the secret to unlocking your mitochondria's whole potential. Go to: https://www.timeline.com/  TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/  IFIT: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about JJ. Virgin: Website: https://jjvirgin.com/Instagram: @jj.virgin
Are you part of the 88% of people who are metabolically unhealthy—and don't even know it? Do you know what metabolic health really means? Or why is it the root cause of nearly every chronic disease? In this episode of Extend, I'm diving deep into the critical world of metabolic health—how it works, why it matters, and what you can do today to optimize it. With only 12% of Americans metabolically healthy, it's time to take charge. I'll break down the science of mitochondria, share the key biomarkers you need to track, and show you how tools like continuous glucose monitors (CGMs) can transform your health. Plus, I'll give you practical, everyday tips to flatten glucose spikes, stabilize your energy, and protect yourself from chronic disease. This episode isn't just about theory—it's about empowering you with tools and tips to optimize your metabolic health and live longer, healthier, and more energized. I Also Discuss:   (00:03) Understanding Metabolic Health and Disease (02:05) The Role of Mitochondria in Energy and Metabolism (05:56) Key Biomarkers for Tracking Metabolic Health (09:35) How Continuous Glucose Monitors Can Transform Your Health (13:40) Mastering Metabolic Health and Vitality   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
What if simple lifestyle changes could transform your health in ways you never imagined? In this episode of Extend with Darshan Shah, MD with my guest, Darin Olien, we dig into the basics—nutrition, exercise, and stress management—that lay the foundation for a healthier life.   Darin also explains why cutting out ultra-processed foods in favor of fresh, whole ingredients is a game-changer for mental clarity, energy, and resilience. From practical tips like staying hydrated to learning the art of nose breathing, we explore how these small, daily habits make a big impact.   We also tackle the hidden influences shaping our food choices and the sneaky ways ultra-processed foods become part of our diets, his powerful journey through plant-based nutrition, touching on the environmental and economic factors tied to our food systems and so much more.   Darin Olien is the author of Fatal Conveniences, where he details exactly what the modern world is doing to our health, and how to fix it. He's also the author of New York Times bestseller SuperLife, host of the SuperLife podcast, and co-host of the Netflix series Down to Earth with Zac Efron.   We also discuss:   (01:35) Relationships, Malibu Fires, and Recovery (07:56) Optimizing Health Through Basic Lifestyle Changes (18:21) Understanding Bioaccumulation and Toxins (23:37) Healthy Eating and Social Media Manipulation (31:54) Impact of Subsidized Meatonomics on Health (44:39) Exploring Super Life for All (01:19:12) Toxic Exposure and Risk Reduction (01:26:19) Detoxifying Your Life Naturally (01:48:17) Navigating Sustainable Business Practices   and more   To learn more about Dr. Darshan Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   To learn more about Darin Olien: Website:  https://superlife.com/ Instagram: https://www.instagram.com/darinolien/
Are you overwhelmed by all the conflicting diet advice out there? In this episode of Extend, I simplify it all with a framework that works: the good, the bad, and the ugly of food. We'll dive deep into how to structure your meals around nutrient-dense choices that nourish your body, help you maintain energy, and support long-term health. I'll walk you through the truth about carbs, proteins, and fats—what you should embrace, what you should avoid, and what's downright harmful. You'll learn why certain carbs can fuel your energy while others spike your blood sugar, why not all fats are created equal, and how to make smarter protein choices. This isn't about restrictions—it's about eating smarter. Tune in to learn how to build a sustainable diet using the 80/20 rule and tips to enjoy your meals while avoiding harmful foods. We Also Discuss: (00:01) Optimizing Health and Longevity Through Nutrition (08:36) Flipping the Food Pyramid: A New Approach to Eating (12:02) The Ugly Truth About Highly Processed Foods (17:07) Navigating Good, Bad, and Ugly Fats (19:58) How to Apply the 80/20 Rule to Your Diet Thank You to Our Sponsor: IFIT: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
What if you could get the full potential of your health by tailoring it to your unique genetic blueprint? Ever wondered how personalized wellness could transform your approach to health and well-being? In this episode of Extend with Dr. Shah, we dive into this fascinating concept with biohacking expert Kayla Barnes Lentz, a pioneer in personalized female health.   Kayla shares her insights on the unique challenges women face, from PCOS and autoimmune conditions to endometriosis and menstrual issues, and explains why a female-specific approach is crucial. She emphasizes that foundational health practices—nutrition, stress management, sleep, and movement—are accessible to everyone and are the building blocks of long-term well-being + her best tips on how to optimize each.    Kayla is the Co-Owner of  LYV The Wellness Space, one of the country's most innovative precision medicine and biology upgrading clinics. Kayla is also the creator and host of the Longevity Optimization Podcast  and co-founder of the Health Optimization Fund.    We also discuss:   (03:55) Optimal Health Through Free Actions (06:13) Toxic Burden from Daily Personal Care Products (08:56) Toxicity Levels in Therapeutic Treatment (12:24) Switching to Healthier, Affordable Products (19:11) TV Red Light Feature Illuminate Home (30:20) Carnivore Diet - Pros and Cons (34:30) Importance of Sleep Monitoring (49:03) Aligning Routines with Menstrual Cycles (48:26) Female-Specific Health Approach (56:20) Nutrition and Supplements for Women (01:04:43) Optimizing Nutrition With Technology (01:26:34) Exploring Health Gadgets and Free Alternatives (01:31:38) Maximizing Routine for Youthful Health   Thank you to our sponsors: Timeline: https://www.timeline.com/ TruNiagen: https://www.truniagen.com/ IFit: https://www.ifit.com/   To learn more about Dr. Darshan Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/    To learn more about Kayla Barnes-Lentz: Website: https://www.kaylabarnes.com/ Instagram: https://www.instagram.com/kaylabarnes/?hl=en
We've all been there—grabbing a quick snack or packaged meal, trusting it to be "not that bad." But what if I told you these ultra-processed foods are quietly undermining your health? Engineered for taste and convenience, they're doing far more harm than you realize, contributing to fatigue, metabolic issues, and even chronic disease. If you're serious about living longer and healthier, this is the conversation you need. In this solo episode of Extend, I break down what's behind ultra-processed foods: how they hijack your hunger signals, damage your metabolism, and disrupt critical hormones. You'll also learn why even a small reduction in these foods can have a massive impact on your health—and how to spot them hiding in plain sight.  This isn't about perfection; it's about progress. Join me as we talk about the changes that matter most—because taking control of what's on your plate could literally save your life. We Also Discuss: (00:26) What Are Ultra-Processed Foods? (04:57) Why Ultra-Processed Foods Are Harmful (07:48) How to Identify Ultra-Processed Foods (09:36) Strategies to Reduce Ultra-Processed Food Intake (11:57) Healthier Dining and Grocery Shopping Tips   Thank you to our sponsor: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/    Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
What if you could customize your health like a pro athlete? Imagine having a health and fitness routine tailored to your unique needs, just like a world-class athlete?! In this episode of Extend with Dr. Shah, we sit down with Dr. Andy Galpin, a leading expert in health and fitness technology, to explore the game-changing innovations that are transforming the industry.   Andy shares insights on how personalized wellness techniques and understanding your individual response to health interventions can take your routine to the next level. From self-experimentation to the power of personalized coaching, we dive into how modern tools are enabling a new era of individualized health and so much more!   Dr. Andy Galpin is a tenured Professor at California State University, Fullerton. He is the Co-Director of the Center for Sport Performance and Founder/Director of the Biochemistry and Molecular Exercise Physiology Laboratory. He is a Human Performance scientist with a PhD in Human Bioenergetics and over 100 peer-reviewed publications and presentations.   We also discuss:   (00:40) Precision Health and Fitness Innovations (12:42) Physical Activity and Exercise Habits (18:20) Balancing Consistency, Progress, and Recovery (27:34) Optimizing Performance Through Comprehensive Testing (32:17) Comprehensive Health and Performance Program (42:12) Body Composition Testing Recommendations (47:50) Importance of Muscle and Cardiovascular Health (01:00:25) Importance of Muscle Function and Testing (01:06:44) Importance of Exercise at Any Age (01:18:46) Strategic Progression in Exercise Programming (01:23:56) Developing Customized Training Programs (01:34:55) Balanced Exercise Regimen for Optimal Fitness (01:42:27) Training Program Flexibility and Adaptation (01:54:53) Interpreting Blood Chemistry Markers in Performance (02:06:05) Blood Biomarker Interpretation for Health (02:14:41) Assessing Physical Readiness and Hydration (02:20:56) Maximizing Nutritional Supplements for Health (02:28:09) Revolutionizing Sleep Testing for Athletes (02:39:36) Advancements in Health Technology (02:42:29) Revolutionizing Digital Training Programs   Thank you to our sponsors: Timeline: https://www.timeline.com/ TruNiagen: https://www.truniagen.com/ IFit: https://www.ifit.com/   To learn more about Dr. Darshan Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   To learn more about Andy Galpin: Website:  https://www.andygalpin.com/  Instagram: https://www.instagram.com/drandygalpin/
Why does a slice of bread today barely resemble the one your grandmother baked? Our food system has transformed dramatically over the decades, turning simple ingredients into what some call "Frankenstein foods." On this week's solo episode of the Extend podcast, I dive deep into how we got here, exposing the missteps and misinformation that have shaped today's diet-driven epidemics of obesity, diabetes, and gut issues.   From the infamous food pyramid to the low-fat craze, I unpack how the government guidelines and industry lobbyists steered us toward a carb-heavy diet, with disastrous results for our health. You'll gain clarity on the roles subsidies and corporate interests played in crafting our food environment—and more importantly, learn how to take back control.   I also discuss:   (00:19) Nutrition Misinformation and Health Reconstruction (06:43) The industrialization of food (09:07) 20% of the information that makes 80% of the difference (10:26) Strategies for Personalized Health Through Nutrition   And more   Thank you to our sponsor: Timeline: https://www.timeline.com/   To learn more about Dr. Darshan Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
Is your metabolic health the key to unlocking overall wellness? In our latest episode, we sit down with Dr. Casey Means, a leading voice in metabolic health, to talk about how your metabolism affects everything from obesity to Alzheimer's.   Dr. Casey also dive into how our industrialized world is disrupting cellular biology and fueling chronic diseases, but she also shares hope through precision health and functional medicine. Plus, she also shared actionable tips to boost wellness, the importance of tracking key biomarkers, improving metabolic function for women in menopause, and so much more!   Dr. Casey Means is a medical doctor, writer, tech entrepreneur, aspiring regenerative gardener, and outdoor enthusiast who lives in a state of care for the miracle and mystery of existence and consciousness. Her book, Good Energy: The Surprising Connection Between Metabolism and Limitless Health is available now!   We also discuss:   (04:24) Mitochondrial Health for Overall Wellness (09:36) The Power of Walking & Movement (15:41) Accessing Ancient and Modern Wisdom (21:53) Metabolic Dysfunction and Obesity (32:45) Early Detection of Health Issues (37:58) Optimal Health and Fasting Glucose (48:26) Understanding Atherogenic Cholesterol Particles (54:21) Promoting Human and Planetary Thriving (01:02:26) Revolutionary AI Simplifies Nutrition Tracking (01:32:00) Blue Zones and Longevity Secrets   To learn more about Dr. Darshan Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   To learn more about Dr. Casey Means: Instagram: https://www.instagram.com/drcaseyskitchen/ Book: https://www.caseymeans.com/goodenergy Website: https://www.caseymeans.com/
Is your health just something you react to when problems arise, or is it something you actively shape every day? For many, the journey to wellness only begins when they're already facing a health crisis. I'm Dr. Darshan Shah, and I know this personally—I went from being overweight and on multiple medications to achieving a level of health I never thought possible. This awakening transformed how I view medicine and inspired me to prioritize an approach that goes beyond treating symptoms to actively enhancing wellness.   In this episode of the Extend podcast, I will discuss the science behind hyper-personalized health and the simple steps you can take to become an active partner in your wellness journey. Because at the end of the day, no one cares more about your health than you do—and with the right strategies, you have the power to transform it.   I also discuss:   (00:43) Mastering Health With New Medical Protocol (05:12) The Wellness Wheel and Pareto Principle (07:44) Prevention Through Early Diagnosis (11:05) Functional Medicine and Systems Biology (15:30) Future of Personalized Preventative Healthcare   and more.   To learn more about Dr. Darshan Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
Are you struggling to find balance in your mental and spiritual well-being? Do you want to feel more grounded, less stressed, and truly connected to your roots?   In this episode of Extend with Dr. Shah, my guest, Jay Shetty shares his journey from monastic life to becoming a global digital creator. We dive deep into the world of meditation, mindset, and stress management, providing practical strategies to cultivate psychological health. Jay reminds us that true happiness comes from within and emphasizes the importance of staying grounded in our values.   We also explore the complex dynamics of vulnerability and trust in relationships, comparing it to trying a new supplement. Together, we discuss how vulnerability leads to deeper connections and the power of seeking professional guidance like life coaches or therapists + so much more.   Jay Shetty is a global bestselling author, award-winning podcast host of On Purpose, Chief Purpose Officer of Calm, and purpose-driven entrepreneur, who has made an indelible impact on hearts and minds worldwide. With an astounding following of over 50 million across social media platforms, Jay Shetty possesses a talent for making purpose and ancient wisdom not only relatable but also practical and easily accessible. His journey of transformation and inspiration has touched the lives of millions across the globe.   We also discuss: (00:00) Mental Health and Wellness Discussion (10:44) Building Trust and Vulnerability in Relationships (17:56) Importance of Self-Assessment for Wellbeing (25:17) Importance of Finding Third Space (36:23) The Power of Surroundings on Stress (42:16) Reconnecting With Nature and Analog Living (49:16) Embracing Nature and Meditation for Wellness (56:33) Understanding Meditation Techniques and Benefits (01:07:28) Digital and Physical Community Dynamics (01:18:49) The Ethics of Technology and Character (01:22:00) Journey to Discovering Purpose and Confidence (01:31:31) Embracing Flexibility and Spiritual Growth (01:41:01) The Power of Healing and Growth   To learn more about Dr. Darshan Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   To learn more about Jay Shetty: Website: https://www.jayshetty.me/ Instagram:https://www.instagram.com/jayshetty/?hl=en
What if the secret to transforming your health isn't about discipline but understanding how your brain is wired? In this episode of Extend with Dr. Shah, I dive into the fascinating science of habit formation and uncover why routines like regular exercise and structured eating are the real keys to long-term health and longevity.   As a physician, I break down how habits automate your actions, helping you conserve mental energy and sustain healthy changes without relying on willpower alone. Drawing inspiration from experts like Charles Duhigg, James Clear, and Malcolm Gladwell, I explore the habit loop—cue, routine, and reward—and how to redesign your environment to reinforce positive behaviors and so much more.   I also discuss:   (00:00) - Mastering the Science of Habit Formation (05:37) - Habit Formation Techniques and Tips (12:58) - Breaking Negative Habits Strategically   To learn more about Dr. Darshan Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
Is your quest for success silently compromising your health? Could the very drive that fuels your ambitions also be leading you away from the balanced life you're striving for? In this episode of The Extend podcast, we dive deep into these intriguing questions with Bryan Johnson, who shares his transformation from a relentless CEO to a passionate health advocate.   We also talked about his journey into humanity's enduring quest for immortality, cutting-edge scientific advancements that could redefine life as we know it plus practical tips on everything from sleep strategies and diet to maintaining a plant-based lifestyle in a world where clean food sourcing is increasingly complex.   Bryan Johnson is an American entrepreneur, venture capitalist, writer and author. He is the founder and CEO of Kernel, a company creating devices that monitor and record brain activity, and OS Fund, a venture capital firm that invests in early-stage science and technology companies.   We also discuss:   (00:05) Health and Technology at Wellness Center (07:56) Impact of Grind Culture on Health (13:31) Health Consciousness and Personal Experiments (29:18) Self Improvement Through Systematic Evolution (34:46) Prioritizing Evidence-Based Nutrition for Longevity (39:29) Nutrition and Fitness Regimen for Strength (46:47) Contaminants in Farmer's Market Produce   To learn more about Dr. Darshan Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   To learn more about Bryan Johnson: Website: https://bryanjohnson.komi.io/ Instagram: https://www.instagram.com/bryanjohnson_/
Are you ready to take control of your health like never before? In a world where healthcare often feels reactive, what if you could become the CEO of your own well-being? In this episode of Extend by Dr. Shah, we're diving into the concept of proactive, personalized health management—an approach that puts you in the driver's seat.   We explore how your genes, lifestyle, and environment all play a role in your biological destiny. You'll learn how to build a health-focused team and identify key performance indicators for your body, just like a CEO would for a company. From tracking your sleep and stress levels to using wearable devices, at-home tests, and so much more.   RESOURCES MENTIONED:  https://darshan-shah-md.kit.com/2f32f7aaba   I also discuss:   (00:19) - Taking Control of Your Health  (05:06) - How to be the CEO of Your Health (06:50) - Empowering Yourself Through Personalized Health (09:17) - Benefits of Wearable Health Devices (15:06) - Supporting Proper Healthcare Decisions   To learn more about Dr. Darshan Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
Could lasting health really be as simple as tweaking a few daily habits? Join me in my first solo of the Extend by Dr. Shah podcast as we explore how subtle shifts in your routine can lead to profound health transformations. I believe that only 20% of what we do leads to 80% of the results we see. So what actually falls into that 20%? What do we actually need to be prioritizing?   In this episode, I answer these questions. I also break down the science of habit formation, focusing on how understanding the habit loop—cue, routine, and reward—can unlock the secret to lifelong wellness. Drawing from James Clear's Atomic Habits, we explore practical strategies like habit stacking, and why building sustainable habits is the key to long-term success + more.   I also discuss:   (02:28) Building a Habit Formation (05:22) How Consistency Can Impact Your Health (06:41) Why Atomic Habits Work (08:51) How Environment Can Have a Profound Effect on your Success (10:30) Mastering Habits   To learn more about Dr. Darshan Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
What if your health depended not just on what you eat, but also on how you move, sleep, and manage stress? In this episode of The Extend Podcast with Dr. Shah, I sat down with my guest, Dr. Mark Hyman, who reveals how focusing on quality over quantity—especially when it comes to food—can transform your health. We dive into the hidden dangers of ultra-processed foods and the power of nutrient-dense diets to regulate appetite and boost well-being. He also highlights the crucial role of muscle mass in longevity, explaining how resistance training supports metabolism, immunity, and hormone health. We explore groundbreaking topics like personalized nutrition, early disease detection, and the impact of environmental toxins. Tune in for a deep dive into how small changes can lead to big health transformations! Dr. Mark Hyman is a leading physician in functional medicine, bestselling author, and founder of the UltraWellness Center. With a focus on addressing the root causes of chronic disease, he advocates for a holistic approach to health that integrates nutrition, lifestyle, and cutting-edge science. Dr. Hyman is also a passionate educator and speaker, inspiring millions to take control of their well-being through personalized, evidence-based care.   We also discuss:   (00:04) Nutrition and Health Optimization (11:01) The Importance of Resistance Training (16:16) Foundational Principles of Health and Disease (20:05) Personalized Nutrition and Health Optimization (25:07) Foundational Thoughts on Medical Education (30:27) Connecting Root Causes of Diseases (39:56) Toxin Detoxification Strategies (46:44) Medical Career Transformation to Functional Medicine (58:07) Revolutionizing Healthcare With Data and AI (01:10:54) The Power of Personalized Medicine (01:15:41) Empowering Self-Health With Data (01:20:06) Comprehensive Health Biomarker Assessment (01:29:07) Early Detection for Preventive Health (01:33:55) Advancements in Alzheimer's Testing and Prevention (01:40:29) Health Transformation With Functional Medicine (01:47:59) Empowering Health Through Understanding Biology   To learn more about Dr. Darshan Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   To learn more about Dr. Mark Hyman: Website: https://drhyman.com/ Instagram:https://www.instagram.com/drmarkhyman/
Extend with Darshan Shah, MD is a podcast dedicated to cutting-edge science, research, tools, and protocols designed to help you extend your healthspan. Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board-certified surgeon and accumulating over two decades of practice, I have discovered that a mere 20% of health knowledge yields 80% of the results. That's why this podcast is all about cutting through the noise on how to turn back the aging clock. I interview world-renowned medical practitioners, doctors, experts, and thought leaders, offering you a step-by-step guide and actionable advice to proactively avoid disease and optimize your health.  Plus, I share weekly solo episodes giving you quick, digestible protocols for successfully extending your healthspan. Find more from Dr. Shah: Instagram: www.instagram.com/darshanshahmd Website: drshah.com Thank you to our sponosor: Next Health Next Health is the top health optimization and longevity center – giving you access to the latest in medicine & aesthetics for a healthier, longer life. Reserve your complimentary private consult with one of our experts: www.next-health.com