On episode #103 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/12 – 3/25/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Probable Japanese Encephalitis Virus Transmission through Organ Transplantation (NEJM) Clinical Characteristics and Severity of Rhinovirus/Enterovirus–Associated Hospitalizations: A Multi-country Analysis from the Global Influenza Hospital Surveillance Network, 2017–2024 (OFID) Bacterial Eagle effect (Wikipedia) THE RATE OF BACTERICIDAL ACTION OF PENICILLIN IN VITRO AS A FUNCTION OF ITS CONCENTRATION, AND ITS PARADOXICALLY REDUCED ACTIVITY AT HIGH CONCENTRATIONS AGAINST CERTAIN ORGANISMS (JEM) Linezolid versus clindamycin for toxin inhibition in severe skin and soft tissue infections: a systematic review and meta-analysis (Infection) Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026 (Critical Care Medicine) Caring for Adult Patients With Sepsis (JAMA) Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026 (Intensive Care Medicine) Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026 (Pediatric Critical Care Medicine) Caring for Pediatric Patients With Sepsis (JAMA) ACEP Will Not Endorse New Sepsis Guidelines from the Surviving Sepsis Campaign (American College of Emergency Physicians) Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With SepsisThe BLING III Randomized Clinical Trial (JAMA) Activation of l-histidine biosynthesis as a new antibiotic strategy against Mycobacterium tuberculosis (Nature Communications) Survival trends in patients with difficult-to-treat, antibiotic-resistant, Gram-negative infections in the era of next-generation antibiotics in the USA: a retrospective cohort study (LANCET: Infectious Diseases) Fungal The Last of US Season 2 (YouTube) Empirical Antifungal Treatment of Critically Ⅲ Patients With Influenza-Associated Acute Respiratory Distress Syndrome: A Propensity Score Weighted Observational Study (CID) Clinical and Radiological Predictors of Invasive Fungal Sinusitis (OFID) Blood Cultures Contain Populations of Genetically Diverse Candida albicans Strains that May Differ in Echinocandin Tolerance and Fitness (JID) Can fluconazole be used to treat non-resistant Candida (Candidozyma) auris infections? Preclinical PK/PD data from a Galleria mellonella infection model (JID) Parasitic Na-GST-1 adsorbed on Alhydrogel co-administered with different Toll-like receptor agonists in hookworm-naive adults using a controlled human infection model in the USA: a phase 2, double-blind, randomised controlled trial (LANCET: Infectious Diseases) Miscellaneous Bridging the Gap: A Needs Assessment of Resources and Support for International Medical Graduates Navigating Visa-Related Career Decisions in Infectious Diseases (OFID) Number Needed to Treat (NEJM) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #102 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 2/26 – 3/11/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Measles Outbreak — New Mexico, 2025 (CDC: MMWR) Epidemiology of HMPV and Other Respiratory Viral Infections Among Outpatients, 2016–2022 (OFID) Notes from the Field: Congenital Rubella Syndrome — Florida, 2025 (CDC: MMWR) Long-term efficacy and safety of the single-dose tetravalent Butantan dengue vaccine (Nature Medicine) Bacterial Clinical Outcomes in Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae Infection: A Cohort Study (JID) Duration of therapy for Pseudomonas aeruginosa bacteremia – a post hoc subgroup analysis from the BALANCE randomized controlled trial (CID) Diagnostic Yield of Tongue Swab- Compared to Sputum-Based Molecular Testing for Tuberculosis in Four High-Burden Countries (CID) WHO recommends near point-of-care tests, tongue swabs, and sputum poolingfor TB diagnosis (WHO) Respiratory virus co-infection is a risk factor for adverse outcomes during Staphylococcus aureus bacteraemia (OFID) Balance Versus Bias: Correcting Misinformation About the 2025 ATS Community-Acquired Pneumonia Guidelines (CID) Fungal The Last of US Season 2 (YouTube) Immunomodulation in the Treatment of Disseminated Coccidioidomycosis (CID) Parasitic Comparison of six weeks doxycycline versus six weeks rifampicin or three weeks of the combination of doxycycline plus rifampicin in the treatment of onchocerciasis: a randomized, placebo-controlled, double-blind, phase 2 trial (OFID) Cutaneous Larva Migrans Within the United States Military Health System – Clinical Presentation and Association with Autochthonous Spread or International Travel (OFID) Miscellaneous Distinct prophage infections in colorectal cancer-associated Bacteroides fragilis (Communications Medicine) Rounding Styles on Inpatient Infectious Disease Consult Services: Impact on Education and Patient-Care Delivery (OFID) Possible quality indicators for clinical infectious diseases consultations – results from a hybrid Delphi-nominal group approach and scenario study (CMI: Clinical Microbiology and Infections) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #101 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 2/12 – 2/25/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Impact of Proviral-DNA M184V/I on 96-Week Outcomes of DTG/3TC Maintenance Therapy: Results From the VOLVER Clinical Trial (CID) Tecovirimat for the Treatment of Mpox (NEJM) Bacterial Multicounty Outbreak of Salmonella Agbeni Linked to Ice in a Cooler at a County Fair — Illinois, August 2024 (CDC: MMWR) Legionella Pneumonia in the Modern Era: Clinical Features and Predictors of Mortality (CID) Cefalexin use in UK acute pyelonephritis practice: unaddressed challenges in dosing, breakpoints and clinical evidence (Journal of Antimicrobial Chemotherapy) Is three really what we need? Relative effectiveness of benzathine penicillin G and doxycycline treatment regimens for late or unknown duration syphilis in 6 United States jurisdictions, 2016–2021 (CID) Show Me the "Mino:" In Vitro Efficacy of Minocycline on Clinical Gram-Negative Bacterial Isolates (Microbial Drug Resistance) Initial Vancomycin Taper for the Prevention of Recurrent Clostridioides difficile Infection (JAMA Network) Microbial Flora in War Wounds from the Ukrainian Front Line (NEJM) Fungal The Last of US Season 2 (YouTube) Epidemiology of Aspergillosis Diagnoses in U.S. Adults using a National EHR Database, 2013-2023 (OFID) Parasitic State-of-the-Art Review: Chagas Disease—an Enduring Challenge (CID) Autochthonous Rat Lungworm Angiostrongylus cantonensis Infections in Accidental and Definitive Hosts, San Diego, California, USA (Emerging Infectious Diseases) Miscellaneous Ancient bacteria strain discovered in ice cave is resistant to some modern antibiotics(CNN) First genome sequence and functional profiling of Psychrobacter SC65A.3 preserved in 5,000-year-old cave ice: insights into ancient resistome, antimicrobial potential, and enzymatic activities (Frontiers in Microbiology) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #100 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 1/29/26 – 2/11/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Type I IFN autoantibodies underlie chikungunya live-attenuated vaccine encephalitis (PNAS) Dengue Suppression by Male Wolbachia-Infected Mosquitoes (NEJM) Assessing the impact of SARS-CoV-2 infection and vaccination on fertility and assisted reproductive techniques outcomes: an umbrella review (Vaccine) Prevalence of CSF HIV VIRAL Escape and Associations With Neurocognitive Outcomes Among HIV-Associated Meningitis Survivors: A Cohort Study (OFID) Adenoviral Inciting Antigen and Somatic Hypermutation in VITT (NEJM) Bacterial Extraintestinal Invasive Escherichia coli Infections in the US (JAMA Network OPEN) Clinical Manifestations, Long-Term Trends, and Risk Factors for Treatment Failure in Native Vertebral Osteomyelitis: A 26-Year Mayo Clinic Experience (CID) US Emergency Department Visits forAntibiotic Adverse Drug Events in Children, 2019-2023 (Journal of the Pediatric Infectious Diseases Society) Fungal The Last of US Season 2 (YouTube) Albumin orchestrates a natural host defence mechanism against mucormycosis (Nature) Pseudo-Outbreak of Purpureocillium lilacinum Skin Infections at a Dermatology Clinic — Washington, 2024 (CDC: MMWR) Candida auris Testing by the Antimicrobial Resistance Laboratory Network, United States, 2022–2023 (Emerging Infectious Diseases) Parasitic Trichinellosis: A zoonosis that still requires vigilance (PLoS Neglected Tropical Diseases) Trichinellosis after Raw Bear Eyeball Consumption (AJTMH: American Journal of Tropical Medicine and Hygiene) Moving Scabies Under Video-Dermoscopy (AJTMH: American Journal of Tropical Medicine and Hygiene) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #99 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 1/15/26 - 1/28/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Symptomatic and asymptomatic norovirus infections in early life; The PREVAIL Cohort, 2017-2020 (CID) Bacterial Xenodiagnosis to search for Borrelia burgdorferi after antibiotic treatment of Lyme disease: a prospective cohort study (CID) Diagnostic Yield of Repeat Blood Cultures and Risk Factors for Bloodstream Infection in Persistent Febrile Neutropenia (CID) Methodology Misrepresented: Correcting the Record on the ATS Community-acquired Pneumonia Guideline Process (CID) Pediatric Infectious Diseases Physicians' Preferences for Management of Clostridioides difficile Infection: An Emerging Infections Network Surve (Journal of the Pediatric Infectious Diseases Society) Antibiotic Therapy for Uncomplicated AcuteAppendicitis (JAMA) Fungal The Last of US Season 2 (YouTube) Persistence of Symptoms among Commercially Insured Patients with Coccidioidomycosis, United States, 2017–2023 (CDC: Emerging Infectious Diseases) Ophthalmologic evaluation and clinical outcome in candidemia: a seven-year retrospective multicenter cohort study (OFID) Parasitic Postinfectious Syndromes and Long-Term Sequelae after Giardia Infections (CDC: Emergining Infectious Diseases) Priced Out of Treatment: The Exorbitant Cost of Antiparasitic Drugs in the United States (OFID) Miscellaneous All About the AAP Recommended Immunization Schedule (healthychildren.org) Recommended Childhood and Adolescent Immunization Schedule: United States, 2026: Policy Statement (American Academy of Pediatrics: Pediatrics) Feeling the Vibes: An Investigation into Resident Antibiotic Prescribing Practices (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #98 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 1/1/26 – 1/14/26. Host: Daniel Griffin Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Rhinovirus-Associated Lower Respiratory Tract Infection in Hospitalized Adult Patients: A Retrospective Cohort Study (JID) Demise of the Milwaukee Protocol for Rabies (CID) Reply to Willoughby on Demise of the Milwaukee Protocol for Rabies (CID) Bacterial Clinical Practice Guideline by Infectious Diseases Society of America (IDSA): 2025 Guideline on Management and Treatment of Complicated Urinary Tract Infections: Introduction and Methods (CID) Reassessing the 2023 International Society for Cardiovascular Infectious Diseases Duke clinical criteria for infective endocarditis: Impact of excluding fever and updating diagnostic definition (CID) The diagnostic accuracy of procalcitonin for community-acquired bacteremia: an updated systematic review and meta-analysis (CMI: Clincal Microbiology and Infection) Noninferiority of One HPV Vaccine Dose to TwoDoses (NEJM) About the wastewater program (Colorado: Department of Public & Environment) Notes from the Field: Wastewater Surveillance for Measles Virus During a Measles Outbreak — Colorado, August 2025 (CDC: MMWR) Notes from the Field: Retrospective Analysis of Wild-Type Measles Virus in Wastewater During a Measles Outbreak — Oregon, March 24–September 22, 2024 (CDC:MMWR) Fungal The Last of US Season 2 (YouTube) Candidozyma auris (formerly Candida auris): Resistant, long-lasting, and everywhere (CMI: Clincal Microbiology and Infection) Long-range air dispersal as an important source of environmental contamination in Candida auris clustering: possible infection control implication (Infection Control & Hospital Epidemiology) Parasitic Dermlite Dermatoscopes (dermatoscopes.com) Oral ivermectin versus 5% permethrin cream to treat children and adults with classic scabies: multicentre, assessor blinded, cluster randomised clinical trials (BMJ) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #97 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 12/18/25 – 12/31/25. Host: Daniel Griffin Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Outcomes Related to Bacterial Co-Infection and Antibiotic Use in Adults Hospitalized With Respiratory Syncytial Virus Compared with Influenza (OFID) Once-Weekly Oral Islatravir Plus Lenacapavir Versus Daily Oral Bictegravir, Emtricitabine, and Tenofovir Alafenamide in Persons With HIV-1 (Annals of Internal Medicine) Bacterial GeoSentinel Analysis of Travelers' Diarrhea Antimicrobial Resistance Patterns (JAMA Open Network) Rapid direct disk diffusion testing for antibiotic resistance in urinary tract infections: a bacterial concentration-adjusted approach (Microbiology Spectrum) Impact of an Educational Leaflet About Asymptomatic Bacteriuria and Urinary Tract Infection on Antibiotic Preferences Among US Adults ≥65 Years: An Online Randomized Controlled Survey Experiment (OFID) Fungal The Last of US Season 2 (YouTube) Real-world Evaluation of Histoplasmosis Diagnosis and Treatment in Patients From a Michigan Health System (OFID) Parasitic Progress Toward Eradication of Dracunculiasis (Guinea Worm Disease) — Worldwide, January 2024–June 2025 (CDC: MMWR) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #96 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 12/4/25 – 12/17/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Rabies Cluster Among Steer on a Dairy Farm — Minnesota, 2024 (CDC:MMWR) Incidence of community-acquired pneumonia and herpes zoster in people with HIV based on CD4-count and age in the current antiretroviral therapy era: a longitudinal cohort study (CID) Associations between antibiotic use and outcomes in patients hospitalized with community-acquired pneumonia and positive respiratory viral assays (CID) Bacterial Lactobacillus Bacteremia: A Challenging Condition for Pediatrician (Pediatric Infectious Disease Journal) Trial of High-Dose Oral Rifampin in Adults with Tuberculous Meningitis (NEJM) Zoliflodacin versus ceftriaxone plus azithromycin for treatment of uncomplicated urogenital gonorrhoea: an international, randomised, controlled, open-label, phase 3, non-inferiority clinical trial (LANCET) Fungal The Last of US Season 2 (YouTube) Compassionate Use of Olorofim for Invasive Mold Infections: A Nationwide Observational Study in France (OFID) Parasitic Eliminating Guinea worm (LANCET: Infectious Disases) Balamuthia mandrillaris Encephalitis in a 12-Year-old Girl: Report of the First Case Diagnosed in Greece (Pediatric Infectious Disease Journal) A Prospective Cohort Longitudinal Study of Human Acute Babesiosis: Quality of Life and Severity of Symptoms Through 1-Year Follow-up (OFID) Body lice and scabies co-infestation among unsheltered migrants, refugees, and asylum seekers and the right to water and sanitation (PLoS Neglected Tropical Diseases) Miscellaneous H.U.S.T.L.E: A Consult Fitness Guide for Infectious Diseases Providers (CID) Seven alternatives to evidence based medical education: an exploration of how we actually teach (BMJ) What does a doctor look like?Asking AI (BMJ) The Receding Specialty of Infectious Diseases and Implications for U.S. Healthcare (OFID) Integrating a host biomarker with a large language model for diagnosis of lower respiratory tract infection (Nature Communications) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #95 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 11/20/25 – 12/3/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Early low-dose dexamethasone is associated with shorter acute symptom duration in Chikungunya virus infection: a retrospective cohort study (BMC Infectious Diseases) Noninferiority of One HPV Vaccine Dose to Two Doses (NEJM) Evidence to Action — Single-Dose HPV Vaccination and Cervical HPV Infection (NEJM) Daily Mosnodenvir as Dengue Prophylaxis in a Controlled Human InfectionModel (NEJM) Universal Hepatitis B Vaccination at Birth—Risks of Revising the recommendation (JAMA) Correlates of HIV-1 control after combination immunotherapy (Nature) Human-to-Human Rabies Transmission via Solid Organ Transplantation from a Donor with Undiagnosed Rabies — United States, October 2024–February 2025 (CDC: MMWR) Cytomegalovirus-specific cell-mediated immunity for prediction of post-prophylaxis CMV disease in a phase 3 trial of letermovir vs valganciclovir prophylaxis in donor CMV-seropositive recipient CMV-seronegative kidney transplant recipients (CID) An Analysis of Cytomegalovirus-Specific Cell-Mediated Immunity in a Phase 3, Randomized, Placebo-Controlled Trial of Letermovir Prophylaxis in Cytomegalovirus-Seropositive Recipients of an Allogeneic Hematopoietic Cell Transplant (CID) Bacterial Infectious Diseases Society of America (IDSA) Position Statement: Why IDSA Did Not Endorse the Community-Acquired Pneumonia Guidelines 2025 Update (CID) Lyme DiseaseIncidence in Massachusetts, 2012-2024 (JAMA: Open Network) Fungal The Last of US Season 2 (YouTube) Aspergillosis-Attributable Mortality in the United States: Analysis of Death CertificateData (CID) Oral itraconazole versus oral voriconazole for treatment-naive patients with chronic pulmonary aspergillosis in India (VICTOR-CPA trial): a single-centre, open-label, randomised, controlled, superiority trial (LANCET: Infectious Diseases) Parasitic Loa loa encephalopathy following treatment with benzimidazole derivatives: A systematic review (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #94 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 11/11/25 – 11/19/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus (Science Translational Medicine) Hepatitis B reactivation following switch away from tenofovir-containing anti-retroviral therapy in people living with HIV: A case series and lessons for practice (CID) Antimicrobial drug-resistant Neisseria gonorrhoeae (GC) infections in men using doxycycline postexposure prophylaxis. A substudy of the ANRS 174 DOXYVAC trial (CID) HIV Pre-exposure Prophylaxis Does Not Increase Gonorrhea and Chlamydia Incidence in Young Black and Hispanic Men who Have Sex With Men: An Observational Cohort Study (OFID) Bacterial Global and regional knowledge of antibiotic use and resistance among the general public: a systematic review and meta-analysis (CMI: Clinical Microbiology and Infection) Infant Botulism Outbreak Linked to Infant Formula, November 2025 (CDC: Botulism) Outbreak Investigation of Infant Botulism: Infant Formula (November 2025) (FDA) Vitamin D deficiency at hospital admission with community-acquired pneumonia is associated with increased risk of mortality: A Prospective Cohort Study (OFID) Bat-Associated Hemotropic Mycoplasmas in Immunosuppressed Children, Spain, 2024 (Emerging Infectious Diseases) A Multicomponent Intervention to Improve Maternal Infection Outcomes (NEJM) Fungal The Last of US Season 2 (YouTube) Increasing Fluconazole Resistance in Candida parapsilosis: A 10-Year Analysis of Blood Culture Isolates at a US Reference Laboratory (2015–2024) (JID) British Society for Medical Mycology best practice recommendations for the diagnosis of serious fungal diseases: 2025 update (LANCET: Infectious Diseases) In Vivo Evolution of Candida auris Multidrug Resistance in a Patient Receiving Antifungal Treatment (JID) Parasitic Implications of a fatal anaphylactic reaction occurring 4 hours after eating beef in a young man with IgE antibodies to galactose-α-1,3-galactose (JACI: Journal of Allergy and Clinical Immunology In practice) WHO recommends R21/Matrix-M vaccine for malaria prevention in updated advice on immunization (WHO) Effectiveness of the RTS,S/AS01E malaria vaccine in a real-world setting over 1 year of follow-up after the three-dose primary schedule: an interim analysis of a phase 4 study in Ghana, Kenya, and Malawi (LANCET: Global Health) A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: Is it time to reconsider the current contraindication? (PLoS Neglected Tropical Diseases) Miscellaneous IL12RB1 deficiency appearing in North America: expanding the clinical phenotypes (CID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #93 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 10/23/25 – 11/10/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral High Prevalence of Varicella Zoster Virus Infection among Persons with Suspect Mpox Cases during an Mpox Outbreak in Kenya, 2024 (ASTMH: AJTMH) Earlier initiation of treatment following HIV acquisition reduces non-AIDS-defining malignancy risk (CID) TWiV 1267: A cancer vaccine and an mpox treatment (MicrobeTV) Cancers Caused by HPV (CDC: Human Papillomavirus (HPV)) Circulating tumor human papillomavirus DNA whole genome sequencing enables human papillomavirus-associated oropharynx cancer early detection (Journal of the National Cancer Institute) Impact of Vaccinating Adult Women Who Are HPV-Positive or with Confirmed Cervical SIL with the 9-Valent Vaccine—A Systematic Review (Viruses) ACIP Shared Clinical Decision-Making Recommendations (CDC: Advisory Committee on Immunization Practices (ACIP)) HPV Vaccination Recommendations (CDC: Vaccines & Immunizations) Bacterial Consequences of Delaying Surgical Intervention in Patients with Native Joint Septic Arthritis (OFID) Fungal The Last of US Season 2 (YouTube) Adjunctive corticosteroids in non-AIDS patients with severe Pneumocystis jirovecii pneumonia (PIC): a multicentre, double-blind, randomised controlled trial (LANCET: Respiratory Medicine) Nasal Iodophor to Reduce Candidozyma auris Nasal Carriage in Nursing Home Residents (OFID) Epidemiology of Invasive Fungal Disease in Pediatric Heart Transplant Recipients (Journal of Pediatric Infectious Diseases Society) Mapping the Geographic Distribution of Dimorphic Mycoses Using a US Commercial Insurance Database (OFID) Genomic Dynamics of the Emergent Candida auris: Exploring Climate-dependentTrends (OFID) Parasitic Evaluation of a One Health public health program based on minimum inputs to control Taenia solium in Madagascar (PLoS Neglected Tropical Diseases) Transplacental Transfer of Lumefantrine, Mefloquine, and Piperaquine: A Comparison of Concentrations in Mothers, Neonates, and Cord Blood (CID) Miscellaneous Amplifying Our Voices: Fostering Advocacy in Infectious Diseases Fellowship(OFID) Plant-Based Diets and Climate Change, A Perspective for Infectious Disease Provider (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #92 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 10/9/25 – 10/22/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Long-term clinical, immunologic, and viral reservoir outcomes in children treated with VRC01LS and 10-1074 monoclonal antibodies in the Tatelo Study (CID) Resistance Analyses of Lenacapavir, Emtricitabine/Tenofovir Alafenamide and Emtricitabine/Tenofovir Disoproxil Fumarate in the PURPOSE 1 and 2 Studies (JID) Susceptibility of measles virus to WHO hand rubs, oral and surface disinfectants (OFID) Measles without rash during acute febrile illness surveillance in Tanzania, 2023-2024 (CID) The 2025 Centers for Disease Control and Prevention Non-Occupational HIV Post-Exposure Prophylaxis Guidelines (CID) Bacterial Paratyphoid fever and relapsing fever in 1812 Napoleon's devastated army (Current Biology) Mass Administration of Azithromycin to Infants in Mali to Reduce Mortality (NEJM) Efficacy and safety of tedizolid in the treatment of acute bacterial skin and skin-structure infections (CMI: Clinical Microbiology and Infection) Zoonotic Escherichia coli and urinary tract infections in Southern California (mBio) Cefdinir Versus Cephalexin for the Treatment of Uncomplicated Urinary Tract Infections (OFID) Fungal The Last of US Season 2 (YouTube) Antagonistic in vitro interaction between olorofim and voriconazole against Aspergillus fumigatus (Journal of Antimicrobial Chemotherapy) Parasitic Miscellaneous CARB Your Enthusiasm: An Ethics-Informed Analysis for Clinicians of the US National Action Plan for Combating Antibiotic-Resistant BacteriaCID) Infection Control in Carceral Facilities (CID) Infection Prevention and Control in Carceral Settings (CID) The Challenge of Malignancies in HIV-1, Beyond Immune Activation and Back to Decreased Immune Surveillance (Journal of AIDS & Clinical Research) SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade (Nature) TWiV 1265: mRNA vaccines make cancer treatment great again (microbeTV) Infected With the Academic Bug (CID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #91 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 9/25/25 – 10/8/25. Host: Daniel Griffin Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral American Academy of Pediatrics Comparison of 2 Doses vs 1 Dose in the First Season Children Are Vaccinated Against Influenza(JAMA: Open Network) Flu and Children (CDC: Influenza (flu)) Bacterial Performance of Different Versions of Duke Criteria in Diagnosing Infective Endocarditis in Patients With Intracardiac Prosthetic (OFID) 2023 Duke criteria on Infectious Disease (Puscast 28) Infective Endocarditis and Antimicrobial Timing: A Case for Delay? (OFID) Tularemia: A Storied History, An Ongoing Threat (CID) Tularemia Antimicrobial Treatment and Prophylaxis: CDC Recommendations for Naturally Acquired Infections and Bioterrorism Response — United States, 2025 (CDC: MMWR) Fungal The Last of US Season 2 (YouTube) Risk factors associated with progression to clinical Candida auris infection among adults with previous colonization—Florida, 2019–2023 (CID) Parasitic Public Health Response to the First Locally Acquired Malaria Outbreaks in the US in 20 Years (JAMA: Open Network) Miscellaneous Fever in sepsis revisited: Is a little heat what we need? (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #90 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 9/12/25 – 9/24/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Crushed Bictegravir/Emtricitabine/Tenofovir Alafenamide (OFID) Tracking County-Level Measles Cases in the US (JAMA Nework) Tracking measles in US (Hopkins) Pediatric influenza-associated encephalopathy and acute necrotizing encephalopathy (MMWR) Clinical recommendations for Lenacapivir (MMWR) Bacterial Primary oral vancomycin prophylaxis to stem an outbreak of Clostridioides difficile infection in intensive care patients (Antimicrob Steward Healthc Epidemiol) Clinical features and treatment strategies of Q fever spinal infection (OFID) Fungal Last of Us Season 2 The Pain is in the Brain (J Inf Dis) Parasitic Chagas Disease, an Endemic Disease in the United States (MMWR) Fixed-dose ivermectin for Mass Drug Administration (PLoS NTD) Outbreak of eosinophilic meningitis caused by the rat lungworm (Angiostrongylus cantonensis) in South Brazil (Am J Trop Med Hyg) Human monoclonal antibody MAM01 for protection against malaria in adults in the USA (Lancet Inf Dis) Permethrin-Treated Baby Wraps for the Prevention of Malaria (NEJM) Miscellaneous Ambient Documentation Technology in Clinician Experience of Documentation Burden and Burnout (JAMA Network Open) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #89 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/18/25 – 9/11/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Antibody Responses are Sustained 2 Years Post-Mpox Infection but not Following Modified Vaccinia Ankara–Bavarian Nordic Vaccination (OFID) Intestinal mucosal immune responses to novel oral poliovirus vaccine type 2 in healthy newborns (CID) Efficacy of Baloxavir Treatment in Preventing Transmission of Influenza (NEJM) Fulminant Viral Myocarditis Associated with Thogotovirus (NEJM) Bacterial Risk factors for 30-Day mortality and the role of empirical therapy in Pseudomonas aeruginosa bloodstream infections(Infection) The Impact of a Nationwide Blood Culture Bottle Shortage in 2024 on Healthcare Facilities in the United States (CID) The effect of commonly used non-antibiotic medications on antimicrobial resistance development in Escherichia coli(NPJ: antimicrobials and resistance) Preoperative Enterosignatures Predict Surgical Site Infections After Abdominal Surgery (OFID) Fungal The Last of US Season 2 (YouTube) Association between Duration of Candidemia and Clinical and Healthcare Resource Utilization Outcomes among Hospitalized Adult Patients with Candidemia Who Received Empiric Treatment with an Echinocandin Across United States Hospitals (CID) Updating the epidemiology of blastomycosis and histoplasmosis in the United States, using national electronic health record data, 2013–2023 (JID) Parasitic Stocking African catfish in Lake Victoria provides effective biocontrol of snail vectors of Schistosoma mansoni (PLoS Neglected Tropical Disease) Miscellaneous Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #88 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/19/25 – 8/27/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Respiratory Syncytial Virus Immunization Coverage Among Infants Through Receipt of Nirsevimab Monoclonal Antibody or Maternal Vaccination (CDC: MMWR) Bictegravir, emtricitabine, and tenofovir alafenamide versus ritonavir-boosted protease inhibitor-based antiretroviral therapy in people with HIV and viral suppression on second-line therapy in Haiti: an open-label, randomised, non-inferiority trial (LANCET: HIV) Interferon-α Nasal Spray Prophylaxis Reduces COVID-19 in Cancer Patients: A Randomized, Double-Blinded, Placebo-Controlled Trial (CID) Bacterial Exposure to suppressive antibiotic therapy in women with recurrent urinary tract infections and severity of infections: a retrospective population-based cohort study (BMJ Open) Effectiveness and safety of antibiotics in kidney transplant recipients with asymptomatic bacteriuria: a systematic review and meta-analysis of randomized controlled trials (OFID) Epidemiological, temporal, and geographic trends of leptospirosis in the United States, 2014–2020 (PLoS Neglected Tropical Diseases) Performance of Tongue Swabs for Tuberculosis Diagnosis in Hospitalized Children Under 5 Years of Age (OFID) Fungal The Last of US Season 2 (YouTube) Towards shorter therapy for candidaemia: defining uncomplicated candidaemia in adults (LANCET: Infectious Diseases) Parasitic Outcomes of Military Blood Donors at Joint Base San Antonio with Reactive Trypanosoma cruzi Antibody Screening (OFID) Cutaneous acanthamoebiasis: Two Cases Highlighting Diverse Histopathologic Findings (Journal of Cutaneous Pathology) Miscellaneous Linezolid-related Optic Nerve Disorders: Insight from a Pharmacovigilance Analysis of the U.S. FDA Adverse Event Reporting System (OFID) Extreme variability in linezolid concentrations in the ICU: A case for routine therapeutic drug monitoring (American Journal of Health-System Pharmacy) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #87 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 7/31/25 – 8/18/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Adjuvanted recombinant zoster vaccine is effective against herpes zoster ophthalmicus, and is associated with lower risk of acute myocardial infarction and stroke in adults aged ≥50 years (CID) Bacterial Dalbavancin for Treatment of Staphylococcus aureus Bacteremia (JAMA) Propensity-Matched Comparison of Timely vs. Delayed Antibiotic Therapy in Stenotrophomonas maltophilia Pneumoni (OFID) The proportion of Treponema pallidum PCR-positive primary syphilis infections which are seronegative for syphilis (OFID) Cefixime versus benzathine penicillin G for the treatment of early syphilis (Journal of Antimicrobial Chemotherapy) Dalbavancin for Treatment of Staphylococcus aureus Bacteremia (JAMA) Fungal The Last of US Season 2 (YouTube) Parasitic Increasing Length of the Babesia Season in New England in the Climate Change Era (OFID) Ivermectin to Control Malaria (NEJM) Miscellaneous ACIP Recommendations Summary (CDC: Influenza) Relative effectiveness of high-dose versus standard-dose influenza vaccine against hospitalizations and mortality according to frailty score (JID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #86 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 7/22 – 8/1/25. Host: Daniel Griffin Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Long-term clinical sequelae among Sudan ebolavirus disease survivors 2 years post-infection (BMC Medicine) Bacterial War on AMR: High MDR carriage rates among war-injured Ukrainian refugees (CMI: Clinical Microbiology and Infection) Oral washes and tongue swabs for Xpert MTB/RIF Ultra-based tuberculosis diagnosis in people with and without the ability to make sputum (CID) Fungal The Last of US Season 2 (YouTube) Progression from Candida auris Colonization Screening to Clinical Case Status, United States, 2016–2023 (CDC: Emerging Infectious Diseases) Regional Emergence of Candida auris in Chicago and Lessons Learned From Intensive Follow-up at 1 Ventilator-Capable Skilled Nursing Facility (CID) Infection Control Guidance: Candida auris (CDC: Candida auris) Twice Weekly Sulfamethoxazole/Trimethoprim for Pneumocystis jiroveci Pneumonia Prophylaxis in Lung Transplant Recipients(Transplant Infectious Disease) Parasitic Toxoplasma gondii infection of neurons alters the production and content of extracellular vesicles directing astrocyte phenotype and contributing to the loss of GLT-1 in the infected brain (PLoS Pathogens) Baylisascariasis (Raccoon Roundworm Infection) in Two Unrelated Children (CDC: MMWR) Miscellaneous A Review of Alpha Gal Syndrome for the Infectious Diseases Practitioner (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #85 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 7/3 – 7/21/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Elimination of HIV Reservoirs Harboring Intact Proviruses (JID) Bacterial Expansion of tetM-Carrying Neisseria gonorrhoeae in the United States, 2018–2024 (NEJM) Study hints doxyPEP use coincides with rise in tetracycline-resistant gonorrhea in US (CIDRAP) Potential Impact of Doxycycline Post-Exposure Prophylaxis on Tetracycline Resistance in Neisseria gonorrhoeae and Colonization With Tetracycline-Resistant Staphylococcus aureus and Group A Streptococcus (CID) Methenamine hippurate asprophylaxis for recurrent urinary tract infections in older women – a triple-blind, randomised, placebo-controlled, phase IV trial (ImpresU). (CMI: Clinical Microbiology and Infection) Diagnosis and Management ofCommunity-acquired Pneumonia(American Journal of Respiratory and Critical Care Medicine) Complicated Urinary Tract Infections (cUTI): Clinical Guidelines for Treatment and Management (IDSA) The impact of an intervention to increase follow-up blood cultures for patients with Staphylococcus aureus bacteriuria (Antimicrobial Stewardship & Healthcare Epidemiology) Fungal The Last of US Season 2 (YouTube) Candida auris Containment Responses in Health Care Facilities that Provide Hemodialysis Services (CDC: MMWR) Candidozyma auris: an emerging threat (Reflections on Infectious Prevention and Control) Effects of postoperative antifungal therapy on the recurrence of Aspergillus infection after pulmonary aspergilloma resection (BMC Infectious Diseases) Triazole-resistant Aspergillus fumigatus in the Netherlands between 1994 and 2022: a genomic and phenotypic study (LANCET: Microbe) Large language models and their performance for the diagnosis of histoplasmosis (PLoS Neglected Tropical Diseases) Parasitic Field evidence of Trypanosoma cruzi infection, diverse host use and invasion of human dwellings by the Chagas disease vector in Florida, USA (PLoS Neglected Tropical Diseases) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #84 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/17 – 7/2/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Clinical Outcomes and Perspectives of People With Human Immunodeficiency Virus Type 1 Twelve Months After Initiation of Long-acting Cabotegravir and Rilpivirine in an Observational Real-world US Study (BEYOND)(CID) Healthcare Provider Knowledge of West Nile Virus Diagnostic Testing—United States, 2022 (OFID) Bacterial Risk and Distribution of Metastatic Infections by Primary Infection Focus in Staphylococcus aureus Bacteremia (OFID) Clinical management of Clostridioides difficile infection with faecal microbiota transplantation (eClinicalMedicine) Clinical Practice Guidelines for the Management of Clostridioides difficile Infection in Adults (IDSA) Clinician Management Preferences for Clostridioides difficile Infection in Adults (OFID) Donor-Derived Tuberculosis In Three Solid Organ Transplant Recipients From The Same Donor (OFID) Septic Arthritis and Osteomyelitis in Finger Caused by Mycoplasma phocimorsus from Brown Bear, Alaska, USA (CDC: Emerging Infectious Diseases) Foodborne Botulism Outbreak After Consumption of Home-Canned Cactus (Nopales) (CDC: MMWR) One-Stage Revision Total Hip Arthroplasty for Polymicrobial Periprosthetic Joint Infection Leads to High Reinfection Rates (Journal of Arthroplasty) 4,000-year-old Mycobacterium lepromatosis genomes from Chile reveal long establishment of Hansen's disease in the Americas (Nature Ecology & Evolution) Fungal The Last of US Season 2 (YouTube) Outcome Predictors of Candida Prosthetic Joint Infection (OFID) Parasitic Miscellaneous Ten Practical Tips for a Successful Presentation at ID clinical case conference (OFID) Evaluating the impact of two decades of USAID interventions and projecting the effects of defunding on mortality up to 2030 (LANCET) Comparison of Periodic In-Person ID Care to Daily Tele-ID Care at a Community Hospital (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #83 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/5 – 6/18/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Premature Demise of the Milwaukee Protocol (CID) West Nile Virus and Other Nationally Notifiable Arboviral Diseases — United States, 2023 (CDC: MMWR) Investigation of associations between the neonatal gut microbiota and severe viral lower respiratory tract infections in the first 2 years of life (LANCET: Microbe) Right blend of gut microbiota could avert hospitalization forviral respiratory infection in babies (CIDRAP) Clinical management and infection prevention and control for mpox: living guideline, May 2025 (World Health Organization) Bacterial Corynebacterium diphtheriaeOutbreak in Migrant Populations in Europe (NEJM) Weekly Oral Cycling Antibiotic Treatment: A New Antibioprophylaxis Regimen for Recurrent UTIs (CID) Fungal The Last of US Season 2 (YouTube) Estimated Burden of Coccidioidomycosis (JAMA) Antifungal therapy in Candida infective endocarditis: a comparison of echinocandins and other treatment regimens in a nation-wide cohort study (CID) Parasitic Does schistosome infection affect behavior through the gut-brain axis? (PLoS Neglected Tropical Diseases) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #82 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/22 – 6/4/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Estimated Current and Future Congenital Rubella Syndrome Incidence with and Without Rubella Vaccine Introduction — 19 Countries, 2019–2055 (CDC: MMWR) HIV-Superinfection in Kidney Transplant Recipients with HIV who Received Organs from Donors with HIV (JID) Respiratory syncytial virus: an under-recognized healthcare-associated infection (Infection Control and Hospital Epidemiology) Bacterial Francisella tularensis Subspecies holarctica in Stranded Beluga Whales, Cook Inlet, Alaska, USA (CDC: Emerging Infectious Diseases) Long-term effects of azithromycin mass administration to reduce childhood mortality on Streptococcus pneumoniae antimicrobial resistance (LANCET: Infectious Diseases) Reducing inappropriate antibiotic use in febrile neutropenia in hematology patients through the implementation of an antibiotic de-escalation protocol (Infection Control and Hospital Epidemiology) Optimizing cefazolin dosing for central nervous system infections: insights from population pharmacokinetics and Monte Carlo simulations (Antimicrobial Agents and Chemotherapy) Fungal The Last of US Season 2 (YouTube) Histoplasma antigenuria prevalence in patients with advanced HIV disease in Côted'Ivoire (CID) Interferon-γ therapy in patients with refractory disseminated coccidioidomycosis(CID) Practical Guidance for Clinical Microbiology Laboratories: Antibody and antigen detection methods for dimorphic fungal infections (Clinical Microbiology Reviews) Parasitic Notes from the Field: Primary Amebic Meningoencephalitis Associated with Nasal Irrigation Using Water from a Recreational Vehicle — Texas, 2024 (CDC: MMWR) Further Evidence for Plausible Transmission of Fishborne Trematodiases in the United States: Game Fish Carry Human-Infectious Trematodes and Are Eaten Raw (JID) Miscellaneous A pilot study of coughing into the shirt to disrupt respiratory pathogen transmission (International Journal Of Emergency Medicine) Applying new compound to bed nets targets malaria parasites, not mosquitoes (CIDRAP) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #81 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 5/8/25 – 5/21/25. Hosts: Daniel Griffin Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Tecovirimat for Clade I MPXV Infection in the Democratic Republic of Congo (NEJM) Remdesivir associated with reduced mortality in hospitalized COVID-19 patients (BMC Infectious Diseases) Real-world evidence shows remdesivir tied to less death in hospitalized COVID patients (CIDRAP) Impact of most promising Ebola therapies on survival (Virology Journal) Bacterial Comparative effectiveness of azithromycin versus doxycycline in hospitalized patients with community acquired pneumonia treated with beta-lactams (CID) Diet and Risk for Incident Diverticulitis in Women (Annals of Internal Medicine) The Dynamics of QuantiFERON-TB Gold In-Tube Conversion and Reversion in a Cohort of South African Adolescents(American Journal of Respiratory and Critical Care Medicine) BCG Revaccination for the Prevention of Mycobacterium tuberculosis Infection(NEJM) The Impact of Diet on Clostridioides difficile Infection (JID) Cefazolin versus Antistaphylococcal Penicillins for the Treatment of Methicillin-Susceptible Staphylococcusaureus Bacteremia (CMI: Clinical Microbiology and Infection) Fungal The Last of US Season 2 (YouTube) Candida auris is emerging as a prevalent urinary pathogen (PLoS Pathgoens A symbiotic filamentous gut fungus ameliorates MASH via a secondary metabolite–CerS6–ceramide axis (Science) Outcome predictors of Candida prosthetic joint infections (OFID) Cave-Associated Histoplasmosis Outbreak Among Travelers Returning from Costa Rica — Georgia, Texas, and Washington, December 2024–January 2025 (CDC: MMWR) Parasitic COPEG 25th Anniversary (US Embassy in Panama) USDA suspends southern border livestock imports over New World screwworm threat(CIDRAP) Moxidectin combination therapies for lymphatic filariasis (LANCET: Infectious Diseases Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #80 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/24/25 – 5/7/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Incidence and Timing of Epstein–Barr Virus Whole Blood DNAemia in Epstein–Barr Virus-Mismatched Adult and Pediatric Solid Organ Transplant Recipients (Transplant Infectious Disease) Infant Respiratory Syncytial Virus Immunization Coverage in the Vaccine Safety Datalink: 2023–2024 (American Academy of Pediatrics) Impact of Nirsevimab on RSV and Non-RSV Severe Respiratory Infections in Hospitalized Infants (Influenza and other respiratory viruses) Hospital admissions of respiratory infections in infants plungewith nirsevimab RSV antibody (CIDRAP) Time to antiviral treatment in mild–moderate COVID-19 in the emergency department (Internal and Emergency Medicine) Delays in COVID antiviral receipt raised risk of poor outcomes after ED visits by 18%, data suggest (CIDRAP) Antiretroviral Postexposure Prophylaxis After Sexual, Injection Drug Use, or Other Nonoccupational Exposure to HIV (MMWR) Bacterial Validation and clinical implementation of cerebrospinal fluid C-reactive protein for the diagnosis of bacterial meningitis (LANCET: Regional Health) Bridging to transplant: TDM-Guided Outpatient Dalbavancin Therapy in Chronic Granulomatous Disease with deep-seeded Inoperable Abscesses over 11 Months (OFID) Nitrites for Urinary Tract Infection—Time to Say Goodbye? (JAMA: Internal Medicine) Fungal The Last of US Season 2 (YouTube) High Mortality and Associated Risk Factors in Kidney Transplant Recipients with Cryptococcosis – A Nationwide Cohort Study Over a Decade Using USRDS Data (OFID) Use of Dog Serologic Data for Improved Understanding of Coccidioidomycosis (JID) Parasitic Performance of a novel P. falciparum rapid diagnostic test in areas of widespread hrp2/3 gene deletion (CID) Prevalence of Anopheles stephensi in the Horn of Africa: a systematic review and meta-analysis (BMC Infectious Diseases) Raising awareness of Demodex mites: a neglected cause of skin disease (Infection) Miscellaneous Scientific Integrity Under Threat: The Role of the IDSA, PIDS, and SHEA Journals in an Evolving Political Landscape (CID) Reasoning on Rounds Volume 2: a Framework for Teaching Management Reasoning in the Inpatient Setting (Journal of General Internal Medicine) Billing for and documentation of provider-to-provider interprofessional consults in infectious diseases (Journal of the Pediatric Infectious Diseases Society) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #79 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/10/25 – 4/23/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral An ancient Epstein-Barr virus genome recovered from a museum penis gourd from Papua (JID) Patterns of Decline in Measles, Mumps, and Rubella Neutralizing Antibodies and Protection Levels Through 10 Years After a Second and Third Dose of MMR Vaccine (OFID) Tecovirimat for Clade I MPXV Infection in the Democratic Republic of Congo(NEJM) Bacterial Rapid tuberculosis diagnosis from respiratory or blood samples by a low cost, portable lab-in-tube assay(Science Translational Medicine) New handheld device can diagnose TB without a lab in under an hour, its developers say(CIDRAP) Maternal mastitis and streptococcal toxic shock syndrome risk from breastfeeding children with scarlet fever (LANCET: Infectious Diseases) Risk Factors for Mortality Among Older Adults with Hospital-Acquired Bloodstream Infections in the Intensive Care Unit(Infectious Diseases and Therapy) Bacteremia in Pediatric Solid Organ Transplant Recipients within 1 Year of Transplant(Transplant Infectious Disease) Oral gepotidacin for the treatment of uncomplicated urogenital gonorrhoea (EAGLE-1) (LANCET) Consequences of Climate Change on the Emergence of Pathogenic, Environmentally Acquired Nontuberculous Mycobacteria (OFID) Addition of Macrolide Antibiotics for Hospital Treatment of Community-Acquired Pneumonia (JID) Point-of-Care Testingby Multiplex-PCR in Different Compartments in Suspected Lower Respiratory Tract Infection After Lung Transplantation(Transplant Infectious Disease) Fungal The Last of US Season 2 (YouTube) Pathway-instructed therapeutic selection of ruxolitinib reduces neuroinflammation in fungal postinfectious inflammatory syndrome (Science Advances) Use of Dog Serologic Data for Improved Understanding of Coccidioidomycosis (JID) Parasitic Uganda launches largest malaria vaccine introduction to date(WHO: Uganda) Long-term follow-up of individuals with Chagas disease treated with posaconazole and benznidazole in a non-endemic region(CMI: Clinical Microbiology and Infection) Miscellaneous Monoclonal Antibodies From Children With Acute Kawasaki Disease Identify a Common Antigenic Target in Fatal Cases Over 5 Decades (Laboratory Investigation) Screwworm Cochliomyia hominivorax (Facebook) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #78 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/27/25 – 4/9/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Demise of the Milwaukee protocol for rabies (CID) A natural experiment on the effect of herpes zoster vaccination on dementia (Nature) Taking a shot at dementia(microbeTV: TWiV) Recommendations from the 10th European Conference on Infections in Leukaemia for the management of cytomegalovirusin patients after allogeneic haematopoietic cell transplantation and other T-cell-engaging therapies (LANCET: Infectious Diseases) Epstein-Barr virus exposure precedes Crohn`s disease development (Gastroenterology aga) Bacterial Blujepa (gepotidacin) approved by US FDA for treatment of uncomplicated urinary tract infections (uUTIs) in female adults and paediatric patients 12 years of age and older (GSK) GSK wins FDA nod for first oral UTI antibiotic in almost 30 years(BioSpace) Efficacy and safety of individualised versus standard 10-day antibiotic treatment in children with febrile urinary tract infection (INDI-UTI): a pragmatic, open-label, multicentre, randomised, controlled, non-inferiority trial in Denmark (LANCET: Infectious Diseases) Frequency and severity of Myasthenia Gravis exacerbations associated with the use of ciprofloxacin, levofloxacin, and azithromycin (Muscle & Nerve) The cost of blood cultures: a barrier to diagnosis in low-income and middle-income countries (LANCET: Microbe) Rethinking blood culture (LANCET: Microbe) Trends in Anaplasmosis Over the Past Decade: A Review of Clinical Features, Laboratory Data and Outcomes(CID) Fungal The Last of US Season 2 (YouTube) Cracks in the curriculum: the hidden deficiencies in fungal disease coverage in medical books (OFID) Kazachstania slooffiae fungemia: a case report and literature review on an emerging opportunistic pathogen in humans (OFID) Plasma microbial cell-free DNS metagenomic sequencing for diagnosis of invasive fungal diseases among high risk outpatient and inpatient immunocompromised hosts (CID) Parasitic Fatal Case of Splash Pad–Associated Naegleria fowleri Meningoencephalitis — Pulaski County, Arkansas, September 2023 (CDC: MMWR) Notes from the Field: Fatal Acanthamoeba Encephalitis in a patient who regularly used tap water in an electronic nasal irrigation device and a continuous positive airway pressure machine at home — new Mexico, 2023 (CDC: MMWR) Malaria (NEJM) Miscellaneous FDA grants marketing authorization of first home test for chlamydia, gonorrhea and trichomoniasis (FDA) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #77 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/13/25 – 3/26/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Food is medicine for human immunodeficiency virus: improved health and hospitalizations in the changing health through food support (chefs-hiv) pragmatic randomized trial (JID) The epidemiology and burden of human parainfluenza virus hospitalizations in u.s. children (Journal of the Pediatric Infectious Diseases Society) Bacterial Epidemiology and outcomes of bloodstream infections in patients in a burns intensive care unit: an eight-year retrospective study(OFID) Prophylactic vancomycin in the primary prevention of clostridium difficile in allogeneic stem cell transplant(Transplant Infectious Disease) Incidence of scrub typhus in rural south India (NEJM) Antibiotic treatment for 7 versus 14 days in patients with bloodstream infections(NEJM) Blood Culture–Negative Endocarditis(Journal of the American Heart Association) Brucella suis Infection in Cardiac Implantable Device of Man Exposed to Feral Swine Meat, Florida, USA (CDC Emerging Infectious Diseases) Hyperbilirubinemia at hospitalization predicts nosocomial infection in decompensated cirrhosis (Hepatology Communicatons) Fungal The Last of US Season 2 (YouTube) Fungal Infections in People Who Use Drugs (OFID) IDSA 2025 guideline update on the treatment of asymptomatic histoplasma pulmonary nodules (histoplasmomas) and mild or moderate acute pulmonary histoplasmosis in adults, children, and pregnant people(IDSA: Infectisous Disease Society of America) Changing trends in the sources and volumes of clinical cultures with Candida auris at a large health system, 2019-2023 (American Journal of Infection Control) Diagnostic test accuracy of the Fungitell serum (1→3)-β-D-glucan assay for the diagnosis of Pneumocystis jirovecii pneumonia: a systematic review and meta-analysis (CMI: Clinical Microbiology and Infection) Parasitic Impact of Strongyloides stercoralis Coinfection on Disease Severity and Treatment Outcomes in Pulmonary Tuberculosis (OFID) Hematology thin smears perform equally to parasitology thick and thin blood smears for the diagnosis of Plasmodium and Babesia infections in a low prevalence setting (Journal of Clinical Microbiology) Notes from the Field: Rhodesiense Human African Trypanosomiasis (Sleeping Sickness) in a Traveler Returning from Zimbabwe — United States, August 2024 (CDC: MMWR) Miscellaneous The history of phage therapy LANCET: Infectious Diseases) Silence=death redux: infectious diseases, public health, and the imperative to resist (CID) Silence = Death, 1990(David Wojnarowicz Foundation) SILENCE=DEATH (B200KLYN Museaum) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #76 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 2/27/25 – 3/12/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Trends in respiratory pathogen testing at us children's hospitals (JAMA Network) Changes in respiratory viral testing before and after the covid-19 pandemic(JAMA Network) Expanding measles outbreak in the United States and guidance for the upcoming travel season (CDC Emergerncy Preparedness and Response) Measles cases and outbreaks (CDC Measles (Rubeola)) Facts and myths about measles (LANCET: Infectious Diseases) Protective effects of recombinant zoster vaccine and antiviral therapy against cardiovascular disease following herpes zoster infection (JID) Chikungunya vaccine information for healthcare providers (CDC Chikungunya Virus) Factors to assess when considering use of chikungunya vaccine(CDC) Bacterial Should patients hospitalized forcommunity-acquired pneumonia be treated with additional antimicrobial agents directed against anaerobes? (American Journal of Therapeutics) Antibiotic-induced loss of gut microbiome metabolic output correlates with clinical responses to CAR T-cell therapy(Blood) Effectiveness of ampicillin/sulbactam versus ceftriaxone for the initial treatment of community-acquired pneumonia in older adults: a target trial emulation study(OFID) Male-partner treatment to prevent recurrence of bacterial vaginosis(NEJM) Fungal The Last of US Season 2 (YouTube) Activity of rezafungin against echinocandin non–wild type candida glabrata clinical isolates from a global surveillance program (OFID) Are contemporary antifungal doses sufficient for critically ill patients? Outcomes from an international, multicenter pharmacokinetics study for Screening Antifungal Exposure in Intensive Care Units—the SAFE-ICU study (Intensive Care Medicine) Parasitic Human alveolar echinococcosis – global, regional and national annual incidence and prevalence rates (CMI: Clinical Microbiology and Infection) Dust to Diagnosis – with MSGERC (FEBRILE) The clinical picture caused by Fasciola gigantica: Analysis of 3,250 patients along the 1995–2019 countrywide spread in Vietnam (OFID) Miscellaneous Reprint of: From medical editors: a call to the global infectious diseases and clinical microbiology community (CMI: Clinical Microbiology and Infection) A hot topic: A climate-focused track for infectious disease fellowship (OFID) Are we being gaslit? A primer for recognizing corporate jargon to overcome gaslighting for the infectious disease workforce (CID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #75 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 2/13/25 – 2/26/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral VIMKUNYA (FDA) Co-infection of SARS‐CoV‐2 and influenza A/B among patients with COVID-19(BMC Infectious Diseases) Measles (Texas Health and Human Services) 2025 Measles outbreak guidelines (New Mexico Health) BTN: Beyond the Noise with Paul Offit (microbeTV) Rubeola response (febrile) Timing of influenza antiviral therapy and risk of death in adults hospitalized with influenza-associated pneumonia, influenza hospitalization surveillance network (FluSurv-NET), 2012–2019 (CID) Mother-child dyads living with HIV in the Western Cape, South Africa: undetectable = undetectable? (Journal of the International AIDS Society) Early impacts of the PEPFAR stop-work order: a rapid assessment(Journal of the International AIDS Society) Prevalence, clinical management, and outcomes of adults hospitalised with endemic arbovirus illness in southeast Europe (MERMAIDS-ARBO): a prospective observational study (LANCET: Infectious Diseases) Bacterial Effects of extended anaerobic antibiotic coverage on anaerobic bloodstream infection: A multisite retrospective stud (International Journal of Infectious Diseases) The effectiveness of newer Beta-Lactams for the treatment of antimicrobial-resistant gram-negative meningitis (CID) Treatment of macrolide-resistant Mycoplasma pneumoniae pneumonia in children: a aeta-analysis of macrolides versus tetracycline (The Pediatric Infectious Disease Journal) Fungal The Last of US Season 2 (YouTube) Concordance of noninvasive plasma cell-free DNA With invasive diagnostics for diagnosis of invasive fungal disease (CID) Invasive fungal infections in patients with liver disease: immunological and clinical considerations for the intensive care unit(Intensive Care Medicine) Parasitic Epidemiologic Investigation of Protozoa and soil-transmitted helminths in Starr County, Texas (American J Trop Med and Hyg) Post-artesunate delayed hemolysis in African children with severe malaria: incidence, medical impact and prevention (CID) Miscellaneous Telehealth (Medicare.gov) Public comment: IDSA guideline on management and treatment of complicated urinary tract infections (IDSA) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #74 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/30/25 – 2/12/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Global Impact of mass vaccination campaigns on circulating type 2 vaccine-derived poliovirus outbreaks (JID) Co-infection of SARS‐CoV‐2 and influenza A/B among patients with COVID-19 (BMC Infectious Diseases) Oseltamivir reduces 30-Day mortality in older adults with Influenza (OFID) Bacterial Predicting benefit from adjuvant therapy with corticosteroids in community-acquired pneumonia (LANCET Respiratory Medicine) Rethinking antibiotic prophylaxis for spontaneous bacterial peritonitis in patients with cirrhosis (CID) Determining the optimal antibiotic duration for skin and soft tissue infections (Current Opinion in Infectious Diseases) The stealth and potentially fatal nature of Kingella kingae outbreaks in daycare facilities (OFID) Piperacillin/tazobactam vs. cefepime or carbapenems for the treatment of bloodstream infections due to bacteria producing chromosomal AmpC beta-lactamase (Infection) Is systemic dissemination of BCG following neonatal vaccination required for protection against Mycobacterium tuberculosis? (JID) Risk of aortic aneurysm or dissection following use of fluoroquinolones: a retrospective multinational network cohort study (eClinical Medicine) Fungal The Last of US Season 2 (YouTube) Developing mRNA lipid nanoparticle vaccine effective for cryptococcosisin a murine model (Vaccines) The araneopathogenic genus Gibellula (Cordycipitaceae: Hypocreales) in the British Isles, including a new zombie species on orb-weaving cave spiders (Metainae: Tetragnathidae) (Fungal Systematics and Evolution) Sensitivity of Coccidioides serologic tests among culture-proven coccidioidomycosis patients with hematological malignancy compared to a matched immunocompetent cohort (Medical Mycology) Parasitic New WHO guidelines for treating rhodesiense human African trypanosomiasis: expanded indications for fexinidazole and pentamidine (LANCET: Infectious Diseases) Miscellaneous Remote practice of infectious diseases through telemedicine (OFID) Telemedicine offers solutions for the rural disparities in infectious disease (ID) care delivery (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #73 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/16/25 – 1/29/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral AGA clinical practice guideline on the prevention and treatment of hepatitis B virus reactivation (Gastroenterology) Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients (Nature Communications) Insect-specific RNA viruses detection in Field-Caught Aedes aegypti mosquitoes from Argentina using NGS technology (PLoS Neglected Tropical Diseases) Bacterial Oral regimens for rifampin-resistant, fluoroquinolone-susceptible tuberculosis (NEJM) Impact of antibiotic treatment and predictors for subsequent infections in multidrug-resistant Pseudomonas aeruginosa catheter-associated asymptomatic bacteriuria (American Journal of Infection Control) Identification of the skip phenomenon among patients With Staphylococcus lugdunensis infective endocarditis (OFID) Emergence of infective endocarditis due to Serratia spp. (OFID) Reduction of vancomycin-associated acute kidney injury with montelukast (JID) Fungal The Last of US Season 2 (YouTube) Pulmonary co-infection of Pneumocystis jirovecii and Aspergillus species (OFID) Impact of fluconazoleon outcomes of patients with primary pulmonary coccidioidomycosis (CID) Parasitic Comparative outcomes of Babesiosis in immunocompromised and non-immunocompromised hosts (CID) Miscellaneous Hidradenitis suppurativa (LANCET) A severe case associated with mixed infections of Pasteurella multocida, Bacteroides pyogenes and Fusobacterium necrophorum due to a snow leopard bite (CMI: Clinical Microbiology and Infection) INSIDE-OUT: Introduction of speakers at IDWeek events (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #72 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/2/25 – 1/15/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Human infection with a novel tickborne Orthonairovirus species in China(NEJM) Antiviral medications for treatment ofnonsevere influenza(JAMA Network: JAMA Internal Medicine) Xofluza (GoodRx) NoroSTATData Table (CDC Norovirus) The discovery of the 27-nm Norwalk virus: an historic perspective (JID) Why the "Ferrari of viruses" is surging through the northern hemisphere (Science) Bacterial Beta-lactams toxicity in the intensive care unit: an underestimatedcollateral damage? (Microorganims) What is the most effective antibiotic monotherapy for severe Pseudomonas aeruginosa infection? (CMI: Clinical Microbiology and Infection) Doxycycline postexposure prophylaxis and bacterial sexually tansmitted infections among individuals using HIV preexposure prophylaxis(JAMA Network: JAMA Internal Medicine) Fungal The Last of US Season 2 (YouTube) Epidemiology and prognostic factors associated with mold-positive blood cultures: 10-year data From a french prospective surveillance program (2012–2022) (CID) Parasitic Safety and efficacy of immunization with a late-liver-stage attenuated malaria parasite (NEJM) Dr. Glaucomflecken explains: late-liver-stage attenuated malaria vaccine (YouTube) Dr. Glaucomflecken X NEJM (YouTube) Albendazole–ivermectin co-formulation for the treatment of Trichuris trichiura and other soil-transmitted helminths: a randomised phase 2/3 trial (LANCET: Infectious Diseases) Miscellaneous A comparison of peripherally insertedcentral catheter materials(NEJM) Considering Islamic frameworks to infectious disease prevention (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #71 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 12/19/24 – 1/1/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Routine detection of viruses through metagenomics: where do we stand? (ASTMH) Rapid selection of HIV-2 capsid mutations in salvage therapy with Lenacapavir-containing regime (CID) Bacterial Ancient genomes reveal a deep history of treponemal disease in the Americas (Nature) The utility of Interferon-γ release assays in the diagnosis of tuberculosis in patients With cancer(Transplant Infectious Disease) A meta-analysis of Levofloxacin for contacts of multidrug-resistant tuberculosis (NEJM Evidence) Tularemia— United States, 2011–2022 (CDC: MMWR) Incorporating incubation period distributions to precisely estimate the association between rainfall and Legionella infection (JID) Fungal The Last of US Season 2 (YouTube) Candida albicans recovered from persistent candidemia exhibit enhanced virulence traits (JID) Mapping the geographic distribution of dimorphic mycoses using a U.S. commercial insurance database (OFID) Comparative efficacy and safety of treatment regimens for Pneumocystis jirovecii pneumonia in people living with HIV – A systematic review and network meta-analysis of randomized controlled trials (CMI: Clinical Microbiology and Infection) Outbreak of Blastomycosis Among Paper Mill Workers — Michigan, November 2022–May 2023 (CDC: MMWR) Parasitic Acanthamoeba Infection in a hematopoietic cell transplant recipient: challenges in diagnosis, management, and source identification (Transplant Infectious Disease) Congenital toxoplasmosis: Fewer clinical signs at 3 years of age over the last 15 years but stable risk of materno-fetal transmission (CID) Miscellaneous Detection of prions in wild pigs (Sus scrofa) from areas with reported chronic wasting disease cases, United States (CDC Emerging Infectious Diseases) Addition of macrolide antibiotics for hospital treatment of community-acquired pneumonia (JID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #70 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 12/5/24 – 12/18/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Epidemiology of Dengue— Puerto Rico, 2010–2024(CDC MMWR) Takeda Announces Voluntary Withdrawal of U.S. Biologics License Application (BLA) for Dengue Vaccine Candidate TAK-003(Takeda) Global health and economic burden of chikungunya from 2011 to 2020 (BMJ Global Health) Bacterial Biomarker-Guided Antibiotic Duration for Hospitalized Patients With Suspected Sepsis (JAMA Network) Say it ain't Steno: a microbiology nudge comment leads to less treatment of Stenotrophomonas maltophilia respiratory colonization(Infection Control & Hospital Epidemiology) Guidelines for the Prevention, Diagnosis, and Management of Urinary Tract Infections in Pediatrics and Adults(JAMA Network) Epidemiology and Outcomes of Antibiotic De-escalation in Patients with Suspected Sepsis in US Hospitals (CID) Effectiveness of ceftazidime–avibactam versus ceftolozane–tazobactam for multidrug-resistant Pseudomonas aeruginosa infections in the USA (CACTUS): a multicentre, retrospective, observational study (LANCET Infectious Diseases) Bedaquiline Monotherapy for Multibacillary Leprosy (NEJM) Fungal The Last of US Season 2 (YouTube) Histoplasmosis Associated With Bat Guano Exposure in Cannabis Grower (OFID) Parasitic TWiV 1175: A hitchiker's guide to virology(microbeTV) Diverse RNA viruses of parasitic nematodes can elicit antibody responses in vertebrate hosts (Nature Microbiology) Neurocysticercosis school outbreak in Belgium (LANCET) Miscellaneous Maintenance of Certification: Is a Knowledge-Based Assessment Really Necessary? (CID) Living happily ever after? The hidden health risks of Disney princesses (BMJ) How to transport a polar bear, and other idiosyncrasies in providing emergency medical services in the Arctic (BMJ) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #69 of the Infectious Disease Puscast, Sara reviews the infectious disease literature for the weeks of 11/21 – 12/4/24. Host: Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Antiretroviral Drugs for Treatment and Prevention of HIV in Adults(JAMA Network) Human Parvovirus B19 Infections Among Pregnant Persons — Minnesota, January–September 2024 (CDC MMWR) Maribavir for refractory cytomegalovirus infection (with or without resistance) in solid organ transplant recipients (Journal of Heart and Lung Transplantation) Bacterial Choosing Wisely: Effectiveness and Safety of Antibiotic Prophylaxis in Close Contacts of InvasiveGroup A Streptococci Infection (CID) Resurgence of pediatric Mycoplasma pneumoniae infections in Southeast Texas, Nov 2023-June 2024 (Journal of Pediatrics Infectious Diseases Society) Fungal The Last of US Season 2 (YouTube) Alternative Pneumocystis Pneumonia Prophylaxis in Solid Organ Transplants(Transplant Infectious Disease) Mortality in chronic pulmonary aspergillosis: a systematic review and individual patient data meta-analysis (LANCET: Infectious Diseases) Parasitic Waterborne Disease Outbreaks Associated with Splash Pads — United States, 1997–2022 (CDC MMWR) Miscellaneous Skin Color Representation in Infectious Disease Textbooks (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #68 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 11/7 – 11/20/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Comparative Emergence of Maribavir and Ganciclovir Resistance in a Randomized Phase 3 Clinical Trial for Treatment of Cytomegalovirus Infection (JID) Yellow fever breakthrough infections after yellow fever vaccination: a systematic review and meta-analysis (LANCET Microbe) Serological evidence of natural exposure to rabies in rural populations in Gabon (PLoS Neglecgted Tropical Diseases) Bacterial Azithromycin Exposure in a 10-Day Window of Myocardial Infarction and Short- and Long-Term Outcomes (JACC Advances) Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections (NEJM) The Long and Winding Road: Three-year Mortality Following Prescription of Multi-drug Antibiotic Treatment for Mycobacterium avium complex Pulmonary Disease in United States Medicare Beneficiaries with Bronchiectasis (OFID) Oral Versus Intravenous Antibiotic Therapy for Staphylococcus aureus Bacteremia or Endocarditis (CID) Carbapenem-resistant Enterobacteriales in solid organ transplant recipients (American Journal of Transplantation) Fungal The Last of US Season 2 (YouTube) Adaptation of Candida albicans to specific host environments by gain-of-function mutations in transcription factors(PLoS Pathogens) Diagnostic Test Accuracy of the Fungitell Serum (1→3)-β-D-Glucan Assay for the Diagnosis of Pneumocystis jirovecii Pneumonia: A Systematic Review and Meta-Analysis (CMI: Clinical Microbiology and Infection) Do patients with candidemia need an ophthalmologic examination? (OFID) Parasitic Progress Toward Global Dracunculiasis (Guinea Worm Disease) Eradication (CDC MMWR) The gut microbiota is essential for Trichinella spiralis—evoked suppression of colitis (PLoS Neglected Tropical Diseases) Symptomatic Entamoeba dispar Infections Among Men Who Have Sex With Men, New York City, 2018control (OFID) Angiostrongylus cantonensis Meningoencephalitis in Three Pediatric Patients in Florida, USA (Journal of the Pediatric Infectious Diseases Society) Miscellaneous Snake phobia among the general population of Tamil Nadu, India(PLoS Neglected Tropical Diseases) Remote Practice of Infectious Diseases Through Telemedicine: Improving Access for Patients and Appeal for Physicians (OFID) Gauging Medical Students' Interests in Infectious Diseases (CID) Shaping the Future of Infectious Diseases: The Journey to Promote Value, Opportunity, and Positive Messaging (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #67 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 10/24 – 11/6/24. Host: Daniel Griffin Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Microbial dynamics and pulmonary immune responses in COVID-19 secondary bacterial pneumonia(Nature) Bacterial Implementation of a Pharmacist-Driven Vancomycin Area Under the Concentration-Time Curve Monitoring Program Using Bayesian Modeling in Outpatient Parenteral Antimicrobial Therapy (OFID) Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin (Nature) Oral Versus Intravenous Antibiotic Therapy for Staphylococcus aureus Bacteremia or Endocarditis(CID) Fungal The Last of US Season 2 (YouTube) Notes from the Field: Trichophyton mentagrophytes Genotype VII — New York City, April–July 2024 (CDC MMWR) Evaluation of Crushed Posaconazole Delayed Release Tablets in Lung Transplant Recipients(Transplant Infectious Disease) Parasitic Outcomes of kidney transplant recipients exposed to Chagas disease under Benznidazole prophylaxis(Transplant Infectious Disease) Fake Aristotle Fakely Rails Against Fighting Inequality (Sententiae Antiquae) Need for a paradigm shift in soil-transmitted helminthiasis control (PLoS Neglected Tropical Diseases) Miscellaneous IDSA Advocacy Results in Big Win for ID in 2025 Final Medicare Rule (IDSA) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice
On episode #66 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 10/8 – 10/23/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Prevalence of Human Papillomavirus (HPV) and HPV Type Distribution in Penile Samples in Young Men in Denmark: Results 10 Years After Implementation of a Girls-Only HPV Vaccination Program (JID) Primary Care Guidance for Providers of Care for Persons With Human Immunodeficiency Virus: 2024 Update by the HIV Medicine Association of the Infectious Diseases Society of America (CID) Bacterial Adjunctive linezolid versus clindamycin for toxin inhibition in β-lactam-treated patients with invasive group A streptococcal infections in 195 US hospitals from 2016 to 2021: a retrospective cohort study with target trial emulation (LANCET: Infectious Diseases) Time to turn off the toxins: adjuvant suppression of group A streptococcus (LANCET: Infectious Diseases) Comparing rates of recurrent infection for first occurrence of Clostridioides difficile between tapered oral vancomycin and standard vancomycin: a retrospective, propensity matched cohort study(Infection Control and Hospital Epidemiology) Evaluation of primary oral vancomycin prophylaxis against C. difficile infection during autologous stem cell transplantation (OFID) Oral Vancomycin to Prevent C. difficile in Stem Cell Transplant Recipients: The last frontier in antimicrobial prophylaxis (OFID) First Report of a Fatal Septicemia Case Caused by Vibrio metoecus: A Comprehensive Functional and Genomic Study (JID) Fungal The Last of US Season 2 (YouTube) A global chromoblastomycosis strategy and development of the global chromoblastomycosis working group(PLoS Neglected Tropical Diseases) Epidemiological and clinical features of a large blastomycosis outbreak at a paper mill in Michigan (CID) Do morphogenetic switching and intraspecies variation enhance virulence of Candida auris? (PLoS Pathogens) Parasitic Beyond Human Babesiosis: Prevalence and Association of Babesia Coinfection with Mortality in the United States, 2015–2022: A Retrospective Cohort Study (OFID) New WHO guidelines for treating rhodesiense human African trypanosomiasis: expanded indications for fexinidazole and pentamidine (LANCET: Infectious Diseases) Miscellaneous Social and Environmental Benefitsof Pediatric Infectious Disease Telemedicine (Journal of the Pediatric Infectious Diseases Society) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #65 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 9/26 – 10/7/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Exploring viral respiratory coinfections: Shedding light on pathogen interactions (PLoS Pathogens) Bacterial ACG Clinical Guideline: Treatment of Helicobacter pylori Infection (American Journal of Gastroenterology) A multivalent mRNA-LNP vaccine protects against Clostridioides difficile infection (Science) The evidence base for the optimal antibiotic treatment duration of upper and lower respiratory tract infections: an umbrella review (LANCET: Infectious Diseases) Population Pharmacokinetic Modeling of Cefepime, Meropenem, and Piperacillin-Tazobactam in Patients With Cystic Fibrosis(JID) Establishment of Amblyomma maculatum Ticks and Rickettsia parkeri in the Northeastern United States (Emerging Infectious Diseases) DETICKT (DETICKT) Early Oral Step-Down Versus Continued Intravenous Antibiotic Treatment of Complicated Intra-Abdominal Infection(Surgical Infections) Fungal The Last of US Season 2 (YouTube) Candida auris: A focused review for emergency clinicians (American Journal of Emergency Medicine) Parasitic Ivermectin-based mass drug administration for scabies in northern India: a single-arm community intervention trial (OFID) Miscellaneous Out-BREAK! : An IDWeek 2023 escape room to break out of the educational mold (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #64 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 9/14 – 9/25/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Outcomes of Intravenous Immunoglobulin treatment of immunocompromised patients with viral respiratory infections (Annals of Allergy, Asthma & Immunology) Comparative Emergence of Maribavir and Ganciclovir Resistance for Treatment of Cytomegalovirus Infection (JID) Antibody persistence and safety of a live-attenuated chikungunya virus vaccine up to 2 years after single-dose administration in adults in the USA (LANCET Infectious Disease) Bacterial Determinant of 30-Day Mortality of Pulmonary Legionellosis (OFID) Donor-derived bartonellosis in Solid Organ Transplant recipients (American Journal of Transplantation) An Opt-Out Emergency Department Screening Intervention Leads to Major Increases in Diagnosis of Syphilis (OFID) Fungal The Last of US Season 2 (YouTube) Fungal disease week (CDC) Bridging Echinocandin with Azole antifungal Therapy On Prevention Of Invasive Candidiasis Post Lung Transplantation (OFID) Early Introductions of Candida auris Detected by Wastewater Surveillance, Utah, USA, 2022–2023 (Emerging Infectious Diseases) Parasitic Toxoplasma gondii Infection of Alzheimer's Disease Mice Reduces Brain Amyloid Density Globally and Regionally (JID) Miscellaneous Effect of Social Distancing Caused by Heavy Snowfall on Seasonal Influenza Epidemic in a Local Region in Japan (Pediatric Infectious Disease Journal) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #63 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/29/24 – 9/13/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Postacute Sequelae of COVID (PASC or Long COVID): An Evidenced-Based Approach (OFID) A New Orthonairovirus Associated with Human Febrile Illness (NEJM) Farmed fur animals harbour viruses with zoonotic spillover potential(Nature) A Cross-Sectional Evaluation of the Virtual Outpatient Management of People With Mpox (OFID) A randomized, placebo-controlled, dose-escalation phase I/II multicenter trial of low-dose cidofovir for BK polyomavirus nephropathy (Transplant Infectious Disease) A Decade of Chronic Norovirus Infection Surveillance at the NIH Clinical Research Center: Clinical Characteristics, Molecular Epidemiology, and Replication (JID) Bacterial FDA clears newLyme disease test (CIDRAP) Lyme ImmunoBlot Receives FDA Clearance(Accesswire) The Utilization Of Echocardiography In Children With Staphylococcus aureus Bacteremia (Journal of Pediatric Infectious Diseases Society) Duration of antibiotic therapy for multidrug resistant Pseudomonas aeruginosa pneumonia: is shorter truly better?(BMC Infectious Diseases) Short Versus Long Antibiotic Duration in Streptococcus pneumoniae Bacteremia (OFID) FDA Marketing Authorization Enables Increased Access to First Step of Syphilis Diagnosis FDA) Clinical impact of pleural fluid Streptococcus pneumoniae PCR testing in children with complicated pneumonia (CID) Duration of antibiotic therapy for multidrug resistant Pseudomonas aeruginosa pneumonia: is shorter truly better? (BMC Infectious Diseases) Short Versus Long Antibiotic Duration in Streptococcus pneumoniae Bacteremia (OFID) Fungal The Last of US Season 2 (YouTube) Incidence and risk factors for invasive fungal infections in patients initiating TNF-alpha inhibitors for inflammatory bowel disease and rheumatoid arthritis (CID) Parasitic Intestinal helminth infection impairs vaccine-induced T cell responses and protection against SARS-CoV-2 in mice(Science Translational Medicine) Miscellaneous Successful Treatment of Refractory Cutaneous Protothecosis With MAT2203, an Oral Lipid Nanocrystal Formulation of Amphotericin B (OFID) The Impact of Infectious Diseases Scholarly Mentorship on Subsequent Infectious Disease Fellowship Application (CID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #62 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/15/24 – 8/28/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Clinician Specialty and HIV PrEP Prescription Reversals and abandonments (JAMA Network: JAMA Internal Medicine) The association between adherence to antiretroviral therapy and viral suppression under dolutegravir-based regimens (JIAS Journal of the International AIDS Society) Dexamethasone in adults with viral meningitis (CMI Clinical Microbiology and Infection) Oropouche Virus Disease Among U.S. Travelers — United States, 2024 (MMWR) Oropouche fever, the mysterious threat (LANCET: Infectious Diseases) Bacterial High rates of Non-susceptibility to common oral antibiotics in Streptococcus pneumoniae clinical isolates (OFID) New York State Department of Health Directs Providers to Discontinue Use of Ciprofloxacin to Prevent Meningococcal Disease Due to Increasing Antimicrobial Resistance (NY State: Department of Health) Tularemia Associated with Harbor Seal Necropsy — Kitsap County, Washington, October 2023 (MMWR) FDA Marketing Authorization Enables Increased Access to First Step of Syphilis Diagnosis (FDA) Clinical impact of pleural fluid Streptococcus pneumoniae PCR testing in children with complicated pneumonia (CID) The Role of the Gut, Urine and Vaginal Microbiome on the Pathogenesis of Urinary Tract Infection (OFID) Fungal The Last of US Season 2 (YouTube) Two dose levels of once-weekly fosravuconazole versus daily itraconazole in combination with surgery in patients with eumycetoma in Sudan (LANCET Infectious disease) Parasitic Usefulness of real-time PCR for urogenital schistosomiasis in preschool children in Angola (PLoS Neglected Tropical Diseases) Helminth infection driven gastrointestinal hypermotility alterations in smooth muscle instead of enteric neurons (PLoS Pathogens) Die-off reaction of Demodex mites after treating demodicosis with oral ivermectin (JAAD case reports) Miscellaneous Prevalence of carbapenem-resistant gram negative bacteria among neonates suspected for sepsis in Africa (BMC Infectious Diseases) New era of targeted clinical guidelines: IDSA (CID) Defining the landscape of educational experiences in transplant infectious diseases (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #61 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/1/20 - 8/14/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral nPEP quick guide (AIDS Education & Training Center Program) Coformulated Bictegravir/Emtricitabine/Tenofovir Alafenamide PREP after sexual assault (OFID) Adopting Early Testing for Perinatal Hepatitis C (Journal of Pediatric Infectious Diseases Society) Bacterial Lower Rates of Staphylococcus aureus Bloodstream Infection in Patients on Hemodialysis Receiving Trimethoprim-Sulfamethoxazole Melioidosis Prophylaxis (OFID) Trimethoprim-Sulfamethoxazole for Staphylococcus Aureus Bacteremia Prophylaxis in Patients on Hemodialysis (OFID) Human monocytotropic ehrlichiosis(PLoS Neglected Tropical Diseases) Human granulocytotropic anaplasmosis (PLoS Neglected Tropical Diseases) Bifidobacterium and Lactobacillus Probiotics for Preterm Infants (JAMA Network: JAMA Pediatrics) Rapid Implementation of Blood Culture Stewardship (CID) BD BACTEC Blood Culture Bottle Shortage - (IDSA) Fungal The Last of US Season 2 (YouTube) Clinical characteristics and mortality risks among critically ill patients with culture-proven coccidioidomycosis(OFID) Poor Clinical and Microbiologic Outcomes in C. auris Bloodstream Infection (CID) Parasitic Soap is lethal for Schistosoma mansoni cercariae (PLoS Neglected Tropical Diseases) Treatment of uncomplicated hepatic cystic echinococcosis (Cochrane Library) Blood exposure to Babesia microti(Cambridge Core) Miscellaneous Absence of Cerebrospinal Fluid Pleocytosis in Encephalitis (CID) Encephalitis due to Infection with Normocellular Cerebrospinal Fluid (CID) Podoconiosis and mental health (PLoS Neglected Tropical Diseases) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
On episode #60 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 7/18/20 – 7/31/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Olympics Swimming in the Seine (NYTimes) Viral Twice-Yearlylenacapavir or Daily F/TAF for HIV Prevention in Cisgender Women (NEJM) Consensus definitions of Cytomegalovirus Infection and Disease in Transplant Patients (CID) The recombinant shingles vaccine is associated with lower risk of dementia (Nature Medicine) Association of the incidence of postherpetic neuralgia with early treatment intervention of herpes zoster (International Journal of Infectious Diseases) Bacterial Updated guidelines for antimicrobial resistant gram-negative infections (IDSA) Put the Vanc Down, Flip it and Reverse it: Comparison of vancomycin and daptomycin (OFID) Durations of antibiotic treatment for acute otitis media and variability in prescribed durations (Journal of Pediatric Infectious Diseases Society) Fungal Adjunctive single-dose liposomal amphotericin to prevent cryptococcal meningitis in people with human immunodeficiency virus (HIV)–associated cryptococcal antigenemia and low plasma cryptococcal antigen (CrAg) titers(CID) Stagonospora cutaneous infection in a kidney transplant recipient: First human case (Transplant Infectious Disease) European Study of cerebral aspergillosis treated with Isavuconazole: an EFISG study (CID) Parasitic Rollout of world's second malaria vaccine begins in Ivory Coast (Healio) Executive summary: Evaluation and management of delusional infestation(CID) Parasitic contamination of soil in the Southern United States (ASTMH) Miscellaneous The potential benefits of delaying seasonal influenza vaccine selections for the northern hemisphere: A retrospective modeling study in the United States (JID) Music is by Ronald Jenkees
On episode #59 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 7/3/20 – 7/17/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral The potential interrelationship of coronary artery disease -herpes zoster (OFID) Bacterial Pharmacokinetics of intravenous antibiotics into the infected pleural space (Thorax) Are gas emissions from microbiology cultures significant contributes to global warming?(OFID) Is combination treatment of ampicillin and gentamicin right for Listeria monocytogenes infection (Infection) Screening organ donors and monitoring recipients for Bartonella quintana (OFID) Neglected Tropical Disease: Rocky Mountain spotted fever (PLoS Pathogen) Updated guidelines for antimicrobial resistant gram-negative infections (IDSA) Fungal Are fungal pathogenssmarter than we are? (microbeTV) What influences the waning of antibodies during cryptococcal meningitis? (JID) Parasitic Artificial Intelligence for filariasis diagnosis and monitoring (PLoS Neglected Tropical Diseases) Is artificial intelligence the end of filariasis? (PLoS Neglected Tropical Diseases Miscellaneous APACHE II severity of disease classification system (GlobalRxPh) Clinical practice guideline for complicated intra-abdominal infections (CID) Procalcitonin or C-reactive protein guided antimicrobial discontinuation to treat sepsis (Critical Care Medicine) The "plague" of plague for the Neolithic population (Nature) Music is by Ronald Jenkees
On episode #58 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/20 – 7/3/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Drink more coffee, reduces risk for SARS-C0V-2 infection (Cell & Bioscience) Cannabis, tobacco…smoking in general NOT good for preventing COVID-19 (JAMA Network OPEN) EBV and KSHV caused HIV associated cancers and lymphoproliferative disorders (Clinical Microbiology Reviews) Where in the CNS can dolutegravir, tenofovir, lamivudine and efavirenz be found? (JID) Therapeutic management of Varicella-Zoster virus meningitis (OFID) Bacterial Carbapenem use in extended-spectrum cephalosporin-resistant Enterobacterales infections (LANCET Infectious Diseases) IDSA guidelines (Columbia University) Guideline-Concordant Therapy for community-acquired pneumonia in the Hospitalized Population (OFID) Interpretive Criteria piperacillin/tazobactam susceptibility test for Enterobacterales (CID) FDA approval forCAPVAXIVE (FDA) 21 valent pneumococcal vaccine approved (Nature Reviews drug discovery) Antimicrobial resistant Staphylococcus aureus isolates (JAMA Network Open) Broad-spectrum antibiotic use for suspected community-onset sepsis (JAMA Network Open) Fungal The Last of Us ( Wikipedia) Challenges to vaccinating against coccidioidomycosis (OFID) Cryptococcosis: the story (OFID) Pneumocystis pneumonia: clinical spectrum, prophylaxis and delayed treatment (Intensive Care Medicine) Improve utilization of 1,3 β-D-glucan Testing(OFID) Music is by Ronald Jenkees
On episode #57 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/6 – 6/19/24. Host: Daniel Griffin Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Is letermovir or valganciclovir better to prevent CMV in kidney transplant recipients (JID) CMV antiviral therapy (GoodRx) Prevalence of and risk for CMV reactivation during COVID-19 pneumonia (PLoS One) Sofosbuvir off-label yellow fever treatment (OFID) Bacterial Preventing resistant gram negative bacteria through beta-lactam de-escalation in sepsis patients (CID) Competing risk analysis, survival analysis that aims to correctly estimate marginal probability of an event (Columbia University) Continuous or intermittent b-lactam infusion for critical sepsis (JAMA Network) Prolonged vs Intermittent Infusions of β-Lactam Antibiotics in Adults With Sepsis or Septic Shock (JAMA Network) Phoenix sepsis score and risk in children with cancer (JAMA Network) New recognized spotted fever group Rickettsia in Northern California (Emerging Infectious Diseases) Screening for mycobacterium tuberculosis (Transplant Infectious Disease) Fungal Potential sexual transmission of Tinea pubogenitalis from TMWII (JAMA Dermatology) Household transmission of tinea infection (OFID) Drug-resistant oral candidiasis in HIV infected patients (BMC Infectious Disease) Parasitic Handheld digital microscope for rapid and comprehensive screening for urogenital and gastrointestinal schistosomiasis (American Journal of Tropical Medicine and Hygiene) Scorecard approach to eliminate onchocerciasis (Am J Trop Med Hyg) Miscellaneous Association between antibiotic receipt and provider rating (OFID) Infectious diseases and infection control prevention strategies when on ECMO (Perfusion) Music is by Ronald Jenkees
On episode #56 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/28 – 6/5/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Rapid detection of chikungunya virus in patient and mosquito samples assays (CMI) Adenovirus and cytomegalovirus specific adoptive T cell therapy for blood transplant and HIV infection (Transplant Infectious Disease) Bacterial Burkholderia pseudomallei: switch from melioidosis to latency (American Journal of Tropical Medicine and Hygiene) Meningococcal Disease circulation during Umrah Pilmgrimage (MMWR Early Release) Dosing and treatment of suppressive antimicrobial therapy against orthopedic implant infections (Jone of Bone and Joint Infection) CDC guidelines for post STD exposure doxycycline admininstration (MMWR) Fungal The last of Us (Wikipeida) Lower (1,3)-beta-d-glucan sensitivity and in vitro levels in Candida auris and parapsilosis strains (CMI) Auto-brewery syndrome in absence of alcohol consumption (Canadian Medical Association Journal) Television debut of auto-brewery syndrome (Vulture) Parasitic Asymptomatic Plasmodium falciparum parasitemia associates with subclinical inflammation (PIDS) Clinical characteristics and outcomes of strongyloidiasis (American Journal of Tropical Medicine and Hygiene) Tafenoquine treatment: relapsing babesiosis (CID) Miscellaneous Medical librarians for infectious diseases rounding teams (OFID) Music is by Ronald Jenkees
On episode #55 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/9 – 5/27/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Highly pathogenic H5N1 in US dairy cattle and 2 human cases (MMWR) Developing novel treatments for acute COVID-19 should address long COVID (JID) Reactivation of inherited HHV 6B in transplant recipient (JID) Bacterial Suppressive antibiotic therapy after DAIRfor acute periprosthetic joint infections (OFID) Piperacillin-tazobactam vs cefepime for sepsis treatment (JAMA Internal Medicine) Are the new diagnostic algorithms for pulmonary tuberculosis more sensitive? (OFID) Social factors associated with congenital syphilis (CID) Oral vancomyin treatment influences Clostridioides difficile recurrence in patients on concurrent systemic antibiotics Association between infectious diseases consultation and morality in Gram negative infected patients (CID) Fungal Not washing your hands: fluconazole-resistant Candida parapsilosis epidemiology (OFID) Retrospective case series: how Candida auris blood infections effect left ventricular assist devices (OFID) Trichophyton indotineae: clinical course, suspectibility and genome sequence (JAMA Dermatology) Screening serum for cryptococcal antigen in liver transplant recipients (OFID) Parasitic US outbreak of human trichinellosis (MMWR) Plague-ing the Pawlowsky glands of human body lice and transmission by bite(PLoS Biology) Miscellaneous Global change drivers and risk of infectious disease (Nature) ID specialists should care about ventilation (CMI) Music is by Ronald Jenkees
On episode #54 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/25 – 5/8/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Dengue: mother and child (American Economic Journal) Dairy farm worker and high path avian influenza A (H5N1) (NEJM) Respiratory virus pre and post transplant outcomes in children (CID) Bictegravir for HIV suppression during pregnancy (CID) Bacterial Group A Streptococcus pharyngitis: rapid diagnostic & antimicrobial stewardship (Pediatric ID Consult) Scrub typhus : Masquerade of disaster (OFID) One size fits all for UTI predictions? (CID) Infections of durable and acute mechanical circulatory support devices (Journal of Heart and Lung Transplantation) Fungal Crypto hosts for cryptococcal disease (NEJM) Parasitic Sampling for cutaneous Leishmaniasis (OFID) Skin monoclonal anti-Malaria antibody therapy (NEJM) Miscellaneous Origin of antimicrobial therapy (CID) Microneedle patches for MR (measles and rubella) vaccination (LANCET) Music is by Ronald Jenkees
On episode #53 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/11 – 4/24/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Reasons for what we do for routine respiratory pathogens (Journal of Hospital Medicine) Acute cardiac events due to RSV infection (JAMA Internal Medicine) Antiretroviral drugs and weight change (CID) What do antibiotics do for acute lower respiratory tract infection (Journal of General Internal Medicine) Guidelines for managing BK polyomavirus in kidney transplantation (Transplant) Bacterial Understanding Yersinia enterocolitica epidemiology(OFID) Medtronic duet external ventricular drain infections(MMWR) Who is more expensive daptomycin or vancomycin (OFID) Fungal Coccidioidomycosis related hospital visits (Emerging Infectious Diseases) Parasitic Leech in oropharynx of a 2-year old leads to anemia (AJTMH) The real use of ivermectin: treatment of strongyloidiasis (AJTHM) Miscellaneous Sporadic CJD in hunters? (Neurology) Where are all the infectious disease doctors? (OFID) Not interested in infectious diseases? Seriously! (CID) Music is by Ronald Jenkees
On episode #52of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/28 – 4/10/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Winter vomiting disease (Open Forum Inf Dis) Ceftriaxone-Resistant Gonorrhea — China, 2022 (MMWR) Give me five days of antibiotics (JPIDS) Where did this come from (JPIDS) Differentiating cellulitis from pseudocellulitis (JAMA Derm) FLIR One Pro Neonatal Elizabethkingia anophelis meningitis from the water reservoir of automated infant milk dispenser (Eurosurveill) d-Mannose for Prevention of Recurrent UTI Among Women (JAMA Int Med) Oral vaccine for UTI potential alternative to antibiotics (Eurek!Alert) Oral vaccine for UTI trials BJUI one and BJUI two and NEJM NLRP3 inflammasome activation and type I interferon signaling predispose to necrotizing fasciitis (Cell Rep Med) Candida deep sternal wound infections: a consequence of antibiotic use? (OFID) Candida auris in US Correctional Facilities (Emerg Inf Dis) Scedosporiosis and lomentosporiosis: difficult-to-treat rare mold infections (Clin Micr Rev) Meeting the consultation surge (OFID) Music is by Ronald Jenkees
On episode #51 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/13 – 3/27/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral The oral antiviral obeldesivir protects NHPs against Sudan ebolavirus (Science) Monoclonal antibody therapy to treat Ebola virus disease (Curr Opinion Vir) Opinion of anti-Sudan ebolavirus antiviral therapy (Science) Management of norovirus in solid organ and hematopoietic stem cell transplants (Transplant ID) Bacterial Bacteremia from urinary source in hospitalized adults with asymptomatic bacteriuria?(JAMA) UTI research reference standards (Lancet Infectious Diseases) Aspiration pneumonia (CHEST) Household transmission of Strep A (JID) Antimicrobial dosing recommendations for obese patients (Antimicrobial Agents and Chemotherapy) Syphilis testing (MMWR) Predictors of morality from streptococcal bacteremia (CID) Fungal Invasive candidiasis (Nat Rev Disease Primer) Climate change and natural disasters impact on fungal infections (Lancet Microbe) Parasitic Nasal flushing and Acanthamoeba infection (Emerging Infectious Diseases) Miscellaneous Vaccination guidelines for adults with cancer (Journal of Clinical Oncology) Do multiplexed molecular diagnostic tools impact treatment for children with acute gastroenteritis? (CID) Music is by Ronald Jenkees
On episode #50 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 2/28 – 3/12/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Measles….and more measles (JPIDS) Need for new mumps vaccine (PIDJ) Cabotegravir and rilpivirine for those infected with HIV (JAMA) Genetic susceptibility to astrovirus diarrhea (OFID) 10 years after hepatitis E vaccination (Lancet) Tecovirimat for improvement of mpox symptoms (OFID) Bacterial Clinical care for tick-borne disease affected by paging clinicians serological results (AJTHM) Metabolomics of nontuberculous mycobacterial pulmonary disease (JID) Predicting risk of infectious endocarditis in those with Staphylococus aureus bacteraemis (JID) Fungal Response to invasive pulmonary aspergillosis (OFID) Parasitic Postsurgical outcomes due to hippocampal sclerosis (AJTHM) Miscellaneous What does the neutrophil to lymphocyte ratio mean in elderly with severe sepsis and diabetes mellitus (BMC Geriatrics) Impact of learning from Febrile podcast for infectious diseases (OFID) Music is by Ronald Jenkees
On episode #49 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 2/14 – 2/27/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral HIV Cure? (NEJM) The effects of HIV-1 antigen-expanded specific T-Cell therapy and vorinostat on persistent infection (JID) The burden of HMPV and influenza associated hospitalizations in adults (JID) Bacterial Length of antibiotic therapy among the hospitalized with uncomplicated pneumonia (Infection Control & Hospital Epidemiology) Guideline on fecal microbiota–vased therapies for some gastrointestinal diseases (Gastroenterology) Guideline on fecal microbiota–based therapies for recurrent C diff (CIDRAP) Reduced vancomycin susceptibility in Clostridioides difficile (CID) Fungal Histoplasmosisin non-HIV population (OFID) Parasitic Plasmodium falciparum under the host's Immune radar(JID) Did you hear Artemether-lumefantrine is recommended for uncomplicate malaria CID) Miscellaneous Uncompensated work in academic infectious diseases, seriously? (CID) Invasive mosquito Anopheles stephensi, Ghana (Emerging Infectious Diseases) Music is by Ronald Jenkees
On episode #48 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/31 – 2/13/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Infectious attenuated tetravalent Butanatan-Dengue vaccine (NEJM) Kids with severe disease following first and second dengue virus infection (Nature) Oropouche fever outbreak in Latin America (Lancet Infectious Diseases) CMV mRNA vaccine knocks out gB/MF59 vaccine (JID) Acyuclovir-resistant mucocutaneous HSV in immunocompromised patients (OFID) Bacterial Dalbavancin for vertebral osteomyelitis (OFID) Severe vibrio vulnificus infections (MMWR) Demystifying UTIs in the era of antibiotic resistance (PLoS Pathogens) Syphilis testing recommendations (MMWR) Doxycycline vs azithromycin for scrub typhus (BMC Infectious Diseases) REALLY drug resistant Pseudomonas aeruginosa outbreak(CID) Fungal SUBA or conventional itraconazole for treatment of endemic mycoses (OFID) Fluconazole resistant Candida (CDC) Are you in the hospital too long after being treated with echinocandin for your Candidemia or invasive Candidiasis (OFID) Nasopharyngeal swab or lower respiratory tract specimen for Pneumocystis jirovecii diagnosis (OFID) Global guideline for cryptococcosis diagnosis and management (Lancet Infectious Disease) Parasitic Toxoplasma IgG positivity associates with increase mortality (AJTMH) Miscellaneous How well did infectious diseases fellows match (JID) Back to the future of the physician-scientist in infectious diseases (JID) Full or not infectious disease training (JID) Music is by Ronald Jenkees
On episode #46 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/18 – 1/31/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Reinfection by Zika via genome diversity and antibody response (EID-Emerging Infectious Disease) People with HIV should breast/chest feed (CID) Norovirus GII in the water (PLoS Water) Herpes zoster and duloxetine premedication for neuralgia (CID) Bacterial SABATO: early oral switch trial (Lancet) Guideline for concordant antibiotic therapy to treat community-acquired pneumonia (Chest) Ceftriaxon with or without Nafcillin/Oxacillin for MSSA treatment (OFID) Ceftriaxone to prevent ventilator-associated pneumonia trial (Lancet) Azithromycin part of routine well-infant visits (NEJM) Burkholderia pseudomallei in Mississippi(NEJM) Cefiderocol red wine urine syndrome in children (Pediatric Infectious Disease Journal) Fungal InsuranceClaims equals blastomycosis Incidence (EID) Antimicrobial stewardship for coccidioidomycosis in endemic region (OFID) Endemic mycosesafter solid organ transplantation (OFID) Parasitic Headbobbing trematoda (CMI) Miscellaneous Suspected hemophagocytic lymphohistiocytosis (JPIDS) BioFire FilmArray for real-life assessment of hospitalized respiratory illness (JID) Clinical microbiology conferences gender and geography (Lancet) Is the toilet really the greatest sanitation invention? (AJICJ) Music is by Ronald Jenkees
On episode #46 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 1/4 – 1/17/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Comparing the performance of three models incorporating weather data to forecast dengue epidemics (JID) Elucidating the impacts of climate on dengue transmission through mathematical models (JID) Infants receiving a single dose of nirsevimab to prevent RSV do not have evidence of enhanced disease in their second RSV season (JPIDS) Patient perspectives on solid organ transplantation from donors with hepatitis C viremia to recipients without hepatitis C viremia (OFID) Oral Beta-Lactams, Fluoroquinolones, or Trimethoprim-Sulfamethoxazole for definitive treatment of uncomplicated Escherichia coli or Klebsiella species bacteremia from a urinary source (OFID) Discontinuation of contact precautions for methicillin-resistant Staphylococcus aureus in a pediatric healthcare system (JPIDS) Oral linezolid compared with benzathine PCN G for treatment of early syphilis in adults (The Lancet) Model-informed precision dosing improves outcomes in patients receiving vancomycin for gram-positive infections (OFID) The Xpert MTB/RIF cycle threshold value predicts M.tuberculosis transmission to close contacts (CID) Efficacy and safety of a structured de-escalation from antipseudomonal β-lactams in bloodstream infections due to Enterobacterales (The Lancet) Oral antibiotics for treatment of Gram negative bacteremia in solid organ transplant recipients (CID) Dematiaceous fungal keratitis with tentacles mimicking Pythium Keratitis (Jama) Verification, analytical sensitivity, cost-effectiveness, and comparison of four Candida auris screening methods (OFID) Tafenoquine-Atovaquone combination achieves radical cure and confers sterile immunity in experimental models of human babesiosis (JID) Relapsing babesiosis with molecular evidence of resistance to certain antimicrobials commonly used to treat Babesia microti infections (OFID) Understanding parental leave policies in ID fellowship (OFID) What's hot this year in ID clinical science (CID) Music is by Ronald Jenkees
On episode #45 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 12/20/23 – 1/3/24. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Notes coming soon Bacterial Change in oral PrEP affect kidney function (OFID) Preventing STIs in women (NEJM) Revising antibiotic and STI trials (NEJM) Treatment for pediatric febrile UTIs (Pediatrics) Burkholderia pseudomallei in Mississippi (NEJM) Acute kidney injury and gentamicin treatment for endocarditis (JACAMR) Pacemakers for Lyme disease patients (OFID) Pseudomonas aeruginosa update and must have references (CMI) Fungal Definining optimal dose liposomal amphotericin B for Candida auris (JID) Cryptococcus neoformans and HIV serology (OFID) Global emergence of Candida auris (OFID) Novel anti-cancer therapeutics and fungal biology (PLoS Pathogens) Parasitic Second malaria vaccine prequalified (WHO) Seasonal vaccination against malaria in children (Lancet ID) Toxoplasma gondii treatement guidelines for patients with haematological malignancies (Lancet ID) Miscellaneous Eye infection review (NEJM) Diagnosing children with gastroenteritis using molecular testing (CID) Are hospital coffee machines pathogenic (BMJ) Putting down the fluoroquinolone (CID) Music is by Ronald Jenkees
On episode #44 of the Infectious Disease Puscast, Sara reviews the infectious disease literature for the weeks of 12/8 – 12/20/23. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Mpox and chickenpox co-infection (J Inf Dis) Corticosteroids for postherpetic neuralgia (Coch Data Syst Rev) Dengue incidence and mortality in Bangladesh (J Inf Dis) ACORN trial vancomycin and piperacillin-tazobactam (Open For Inf Dis) Models for infection risk in children with cancer (J Clin Oncol) Salmonella outbreak from cantaloupes (CDC) Pediatric antimicrobial stewardship programs ( Ped Inf Dis Soc) MRSA nasal swab PCR assay (J Ped Inf Dis Soc) Invasive meningococcal disease (Open For Inf Dis) Probiotics for recurrent UTI (Clin Inf Dis) Preservation fluid contamination and kidney transplant patients (Transpl Inf Dis) Mechanism of zinc prevention of candidiasis (Sci Transl Med) Risk factors for invasive fungal infection (Open For Inf Dis) Genetic variants associated with S. mansoni worm burden (PLoS NTD) Chagas disease GI manifestations (Am J Trop Med Hyg) Wolbachia in Aedes aegypti in Colombia (PLoS NTD) Music is by Ronald Jenkees
On episode #43 of the Infectious Disease Puscast, Sara reviews the infectious disease literature for the weeks of 11/22 – 12/06/23. Host: Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Treatment for first cytomegalovirus infection post-hematopoietic cell transplant (CID) Mortality among children aged antiretroviral treatment (CDC) Boostability after single-visit pre-exposure prophylaxis with rabies vaccine (The Lancet) Alarming trends in dengue incidence and mortality in Bangladesh (JID) Update on cardiovascular implantable electronic device infections and their prevention, diagnosis, and management (Circulation) SCCM/IDSA guidelines for evaluating new fever in adult patients in the ICU (IDSA) Risk factors for serogroup B meningococcal disease among college students (OFID) Comparison of Adjuvant Clindamycin vs Linezolid for severe invasive Group A Streptococcal skin and soft tissue infections (OFID) State of the art reviews: Persistent enterococcal bacteremia (CID) Billirud Mill Blastomycosis outbreak (MM) Primaquine radical cure in patients with P.falciparum malaria in areas co-endemic for P falciparum and P vivax (The Lancet) Microbiology, public health, and the murals of Diego Rivera (CID) Music is by Ronald Jenkees
On episode #42 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 11/09 – 11/21/23. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Progress toward measles elimination (CDC) Slaying the troll of transplantation (TID) Association between the neutrophil-to-lymphocyte ratio and adverse outcomes in children aged Pre-exposure prophylaxis use history in people with antiretroviral resistance at HIV diagnosis (CID) Impact of the 2019 FDA guidance for uncomplicated UTI on treatment response rates (OFID) CDC Guidelines for the prevention and treatment of anthrax (CDC) Contemporary use of cefazolin for MSSA infective endocarditis (IJID) Is carbapenem therapy necessary for treatment of non-CTX-M ESBL-producing Enterobacterales bloodstream infections (CID) Infectious diseases consultation associated with reduced mortality in gram-negative Bacteremia (CID) Contemporary management of Staphylococcus aureus bacteremia (CID) Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal (Nature) Impact of in-house Candida auris PCR screening on admission on the incidence rates of surveillance and blood cultures with C. auris and associated cost savings (OFID) Human lobomycosis caused by Paracoccidioides loboi (EID) Molecular surveillance detects high prevalence of the neglected parasite Mansonella ozzardi (JID) Efficacy and safety of moxidectin compared with ivermectin against Strongyloides stercoralis infection in adults (The Lancet) Efficacy of bortezomib for treating anti-interferon-gamma autoantibody-associated adult-onset immunodeficiency (AOID) syndrome (CID) Investigational non-antibiotic therapeutics for infections in hematopoietic cell transplant recipients and patients with hematologic malignancies receiving cellular therapies (TID) Black box warning: large language models and the future of infectious diseases consultations (CID) Music is by Ronald Jenkees
On episode #41 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 10/26 - 11/08/23. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS Become a patron of Puscast! Links for this episode Intrinsic and effective severity of COVID-19 cases infected with the ancestral strain and Omicron BA.2 variant in Hong Kong (JID) Efficacy and safety of corticosteroid therapy for community-acquired pneumonia (CID) Hydrocortisone in severe community-acquired pneumonia (NEJM) Early oral antibiotic switch in Staphylococcus aureus bacteraemia (CID) Outbreak of invasive Group A Streptococcus in children (PIDS) Inhaled amikacin to prevent ventilator-associated pneumonia (NEJM) Assessing risk for complications in acute hematogenous osteomyelitis in children (JPIDS) Empirical antibiotic therapy in diabetic foot ulcer infection increases hospitalization(OFID) 2023 guideline on diagnosis and management of acute bacterial arthritis in pediatrics (JPIDS) Natural history of antibiotic-treated lower limb cellulitis (OFID) Missed opportunities for preventing congenital syphilis (CDC) Diverse clinical manifestations and challenges of mucormycosis (OFID) Malaria (The Lancet) Clinical characteristics and outcomes of Chagas disease (AJTMH) Direct gloving vs hand hygiene before donning gloves in adherence to hospital infection control practices (JAMA) How I approach diarrhea in hematological transplant patients (TID) Innovating pediatric infectious diseases recruitment and training (JPIDS) Music is by Ronald Jenkees
On episode #40 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 10/13 – 10/25/23. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Sustained viral suppression with dolutegravir monotherapy over 192 weeks in patients starting combination antiretroviral therapy during primary HIV infection (CID) Dolutegravir monotherapy possibly boosted by highly active natural immunity (CID) Mpox neutralizing antibodies at 6 months from mpox infection or MVA-BN vaccination (The Lancet) Linezolid population pharmacokinetic model in plasma and cerebrospinal fluid among patients with tuberculosis meningitis (JID) Adjunctive dexamethasone for tuberculous meningitis in HIV-positive adults (NEJM) Cefepime vs piperacillin-tazobactam in adults hospitalized with acute infection (JAMA) Acute kidney injury with empirical antibiotics for sepsis (JAMA) Mycobacterium abscessus outbreak related to contaminated water among ventilator-dependent residents of a pediatric facility (CDC) Trial of Vancomycin and Cefazolin as surgical prophylaxis in arthroplasty (NEJM) Trimethoprim-sulfamethoxazole significantly reduces the risk of nocardiosis in solid organ transplant recipients (CMI) Risk of hematologic cancers among individuals tested for Borrelia burgdorferi antibodies, and Borrelia burgdorferi seropositive individuals (CMI) In vitro susceptibility patterns for slowly growing non-tuberculous mycobacteria (JAC) Real-world use of mold-active triazole prophylaxis in the prevention of invasive fungal diseases (OFID) Fungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19 (INI) Real-time dermoscopy of numerous mites crawling on the crusted scabies (CMI) The African eye worm: current understanding of the epidemiology, clinical disease, and treatment of loiasis (The Lancet) Decolonization in nursing homes to prevent infection and hospitalization (NEJM) Can chatbot artificial intelligence replace ID physicians in the management of bloodstream infections (CID) Nasal iodophor antiseptic vs nasal mupirocin antibiotic in the setting of chlorhexidine bathing to prevent infections in ICUs (JAMA) FDA Approves PENBRAYATM for the prevention of the five most common serogroups causing meningococcal disease in adolescents (Pfizer) Music is by Ronald Jenkees
On episode #39 of the Infectious Disease Puscast, recorded at IDWeek in Boston, Daniel and special host Priya Kodiyanplakkal review the infectious disease literature for the weeks of 9/27 – 10/12/23. Host: Daniel Griffin and Priya Kodiyanplakkal Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Survival from rabies in a young child from India (AJTMH) The perils of overly-sensitive viral load testing for persons living with HIV (OFID) Letermovir vs Valganciclovir for prophylaxis of Cytomegalovirus in high-risk kidney transplant recipients (JAMA) Frailty and survival in the 1918 influenza pandemic (PNAS) Adverse pregnancy outcomes among HIV-infected Women taking isoniazid preventive therapy during the first trimester (CID) Ceftobiprole for treatment of complicated Staphylococcus aureus bacteremia (NEJM) Real-world application of oral therapy for infective endocarditis (CID) Efficacy and safety of sulbactam–durlobactam versus colistin for the treatment of patients with serious infections (The Lancet) Information delay of significant bloodstream isolates and patient mortality (CID) Critical appraisal beyond clinical guidelines for intra-abdominal candidiasis (CC) Update on outbreak of fungal meningitis among Americans who received epidural anesthesia at clinics in Mexico Increasing prevalence of artemisinin-resistant HRP2-negative malaria in Eritrea (NEJM) Gender differences in psychosocial determinants of hand hygiene among physicians (ICHE) Music is by Ronald Jenkees
On episode #38 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 9/14 – 9/27/23. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Features of Long COVID identified through immune profiling (Nature) Severity of influenza-associated hospitalizations by influenza type (The Lancet) Cefazolin for the treatment of CNS infections (CID) Rifampin based therapy for patients with Staphylococcus aureus native vertebral Osteomyelitis (CID) State of the management of infections caused by multidrug-resistant organisms (CID) Are contact precautions "essential" for the prevention of healthcare-associated methicillin-resistant Staphylococcus aureus? (CID) Impact of the sequential implementation of a pharmacy-driven methicillin-resistant Staphylococcus aureus (MRSA) nasal-swab ordering policy and vancomycin 72-hour restriction protocol on standardized antibiotic administration ratio (ICHE) Update on outbreak of fungal meningitis among US residents who received epidural anesthesia at two clinics in Mexico (CID) Paratracheal abscess by plant fungus Chondrostereum purpureum (MMCR) Canadian Blood Services traceback investigation of a suspected case of transfusion-transmitted malaria (Transfusion) Strongyloides infection screening in transplant candidates (TID) The world of microbial odors (JID) Music is by Ronald Jenkees
On episode #37 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 8/31 – 9/13/23. Host: Daniel Griffin and Sara Dong Click arrow to play Download Puscast 037 (22 MB .mp3, 31 min) Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Association between varicella zoster virus and dementia (NS) Safety, efficacy, and immunogenicity of V160 vaccine in cytomegalovirus-seronegative women (The Lancet) Microorganisms detected in intussusception cases and controls in children (OFID) Clinician testing and treatment thresholds for management of UTIs (OFID) Clinical outcomes and management of NAAT-positive/toxin-negative Clostridioides difficile infection (CID) Associations of standard care, intrathecal antibiotics, and antibiotic impregnated catheters with cerebrospinal fluid shunt infection (JPIDS) Advances in asynchronous telemedicine call for increased antibiotic surveillance (CID) Two artificial tears outbreak-associated cases of extensively drug-resistant Pseudomonas aeruginosa detected through whole genome surveillance (JID) Pre-XDR congenital TB in an extremely premature baby (CID) Emerging Roles of (1→3)-β-D-glucan in cerebrospinal fluid for detection and therapeutic monitoring of fungal diseases (CID) Outbreak of locally acquired mosquito-transmitted malaria (CDC) Complexity of infectious diseases compared to other cognitive medical subspecialties (OFID) Risk of opportunistic infections associated with long-term glucocorticoid therapies in adults (CID) Music is by Ronald Jenkees
On episode #36 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 8/17 – 8/30/23. Host: Daniel Griffin Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Detection of rotavirus in respiratory specimens from children aged under 2 years hospitalized for acute gastroenteritis (JID) Risk of Bell's palsy following SARS-CoV-2 infection (CMI) Evaluation and management of diabetes-related foot infections (CID) Impact of mandatory infectious disease specialist approval on Clostridioides difficile infection rates and testing appropriateness (CID) Role of cerebral imaging on diagnosis and management in patients with suspected infective endocarditis (CID) Identifying effective durations of antibiotic therapy for the treatment of carbapenem-resistant Enterobacterales bloodstream infections (CID) Impact on clinical outcome of follow-up blood cultures and risk factors for persistent bacteraemia (CMI) State-of-the-art review: Neurosyphilis (CID) Oritavancin compared to the standard of care for treatment of non-endovascular gram-positive bloodstream Infections (OFID) How to approach suppressive antibiotic therapy following debridement, antibiotics, and implant retention for prosthetic joint infection (CID) 2023 Duke-International Society for cardiovascular infectious diseases criteria for infective endocarditis (CID) Adjunctive diagnostic studies completed following detection of candidemia in children (JPIDS) Oral lipid nanocrystal amphotericin b for cryptococcal meningitis (CID) Efficacy of 23 commonly used liquid disinfectants against Candida auris (IC&HE) Burrow ink test for scabies (NEJM) Evolution of partial resistance to artemisinins in malaria parasites in Uganda (NEJM) Human neural larva migrans caused by Ophidascaris robertsi ascarid (EID) Music is by Ronald Jenkees
On episode #35 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 8/3 – 8/16/23. Host: Daniel Griffin Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Powassan virus encephalitis: a tertiary center experience (CID) Diagnostic accuracy of hospital antibiograms in predicting the risk of antimicrobial resistance in Enterobacteriaceae isolates (CID) Timely diagnosis of incubating syphilis infections using Treponema pallidum (CID) Impact of rapid identification and stewardship intervention on coagulase-negative Staphylococcus bloodstream infection (OFID) Natural antibodies mediate protection against Acinetobacter baumannii respiratory infections (JID) Risk of misleading conclusions in observational studies of time-to-antibiotics and mortality in suspected sepsis (CID) Cryptococcal meningitis in young, immunocompetent patients (OFID) Experimental acquisition, maintenance, and transmission of methicillin-resistant Staphylococcus aureus (MRSA) (JID) Clinical characteristics and prognosis of pediatric Phthirus pubis coinfestation of the eyelashes and scalp hairs (AMJTMH) Prognostic significance of Lymphocyte Subpopulations for ICU-acquired Infections in sepsis patients (JHI) Music is by Ronald Jenkees
On episode #34 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 7/20 – 8/2/23. Host: Daniel Griffin Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode FDA approves first treatment for molluscum contagiosum (FDA) Identifying children likely to benefit from antibiotics for Acute Sinusitis (JAMA) Impact of metagenomic next-generation sequencing of plasma cell-free DNA testing in patients with suspected infectious diseases (OFID) Impact of infectious diseases consultation in patients with candidemia at a multisite healthcare system (OFID) Relapsing babesiosis with molecular evidence of resistance to certain antimicrobials commonly used to treat Babesia microti infections (OFID) Seroprevalence of Chagas disease among people of Latin American descent (AJTMH) Malaria transmission-blocking vaccines Pfs230D1-EPA and Pfs25-EPA in Alhydrogel in healthy Malian adults (The Lancet) The human blood fluke, Schistosoma mansoni, harbors bacteria throughout the parasite's life cycle (JID) Health care provider knowledge regarding Alpha-gal syndrome (CDC) Music is by Ronald Jenkees
On episode #33 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 7/6 – 7/19/23. Host: Daniel Griffin Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Early antiretroviral therapy not associated with higher cryptococcal Meningitis mortality in people with HIV in high-income countries (CID) Implementing a rapid Antiretroviral therapy program using starter packs for emergency department patients diagnosed with HIV infection (OFID) Efficacy of a clinical decision rule to enable direct oral challenge in patients with low-risk Penicillin allergy (JAMA) Infectious diseases consultation associated with reduced mortality in gram-negative bacteremia (CID) Positive impact of [18F]FDG-PET/CT on mortality in patients with Staphylococcus aureus Bacteremia explained by immortal time bias (CID) Azithromycin for bacterial watery diarrhea (JID) Periprosthetic joint infection: current clinical challenges (CID) Old World medieval Treponema pallidum complex treponematosis (JID) Clinical Impact of polymerase chain reaction–based Aspergillus and Azole resistance detection in invasive aspergillosis (CID) Superior accuracy of Aspergillus plasma cell-free DNA PCR over serum galactomannan for the diagnosis of invasive aspergillosis (CID) Tafenoquine co-administered with dihydroartemisinin–piperaquine for the radical cure of Plasmodium vivax malaria (The Lancet) Doubling of cyclosporiasis cases partially attributable to a salad kit (CDC) Efficacy and safety of adjunctive corticosteroids in the treatment of severe community-acquired pneumonia (BMC) Music is by Ronald Jenkees
On episode #32 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/21 – 7/4/23. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Clinical characteristics and outcomes among travelers with severe dengue (AIM) Phase 3 randomized trial of Bulevirtide in chronic hepatitis D (NEJM) Increased peripheral inflammation associated with structural brain changes and reduced blood flow in virologically controlled people with HIV (JID) Sustained viral suppression with dolutegravir monotherapy over 192 weeks in HIV patients (CID) Side-by-side comparative study of the immunogenicity of the intramuscular and intradermal rabies post-exposure prophylaxis regimens in suspected RABV exposed individuals (CID) Reliability of admission procalcitonin testing for capturing bacteremia across the sepsis spectrum (CCM) Early discontinuation of antibiotics in patients admitted with clinically suspected serious infection but negative cultures (OFID) Short-course therapy for urinary tract infections in children (JAMA) Autochthonous Leprosy in the United States (NEJM) Management of pediatric pneumonia (CID) Added value of (1,3)-β-D-glucan for the diagnosis of Invasive candidiasis in ICU patients (Infection) Selection for insecticide resistance can promote Plasmodium falciparum infection in Anopheles (PLOS Pathogens) Locally acquired malaria cases identified in the US (CDC) Nanoplasmonic amplification in microfluidics enables accelerated colorimetric quantification of nucleic acid biomarkers from pathogens (NN) Music is by Ronald Jenkees
On episode #31 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/8 – 6/20/23. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Relative effectiveness of the cell-based quadrivalent influenza vaccine in preventing cardiorespiratory hospitalizations (OFID) Evaluation of Oseltamivir used to prevent hospitalization in outpatients with influenza (JAMA) Pan-ebolavirus monoclonal antibody cocktail provides protection against Ebola and Sudan viruses (JID) Inappropriate antibiotic prescribing and its determinants among outpatient children in low-and middle-income countries (PLOS) IDSA 2023 Guidance on the treatment of antimicrobial resistant gram-negative infections (IDSA) Evaluating antimicrobial duration for gram-negative bacteremia in patients with neutropenia (TID) Antibiotic myths for the ID clinician (CID) Dalbavancin for the treatment of acute bacterial skin and skin structure infection in patients with obesity or Diabetes (OFID) Global differences in the management of S. aureus bacteremia (CID) Clinical risk Scores to Predict Trimethoprim-Sulfamethoxazole, Fluoroquinolone, Nitrofurantoin, and Cephalosporin non-susceptibility among outpatient episodes of complicated UTI among adults (OFID) Continuous vs intermittent meropenem administration in critically ill patients with sepsis (JAMA) Current pyuria cutoffs promote inappropriate UTI diagnosis in older women (CID) Paenibacillus infection as a novel cause of sepsis in term neonates with high risk of sequelae in Uganda (CID) Antimicrobial for 7 or 14 Days for febrile urinary tract infection in men (CID) Candida auris‒associated hospitalizations (EID) Fatal invasive mold infections after transplantation of organs recovered from drowned donors (EID) Music is by Ronald Jenkees
On episode #30 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/24 – 6/7/23. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Foodborne illness outbreaks at retail food establishments (CDC) Donor-derived fulminant herpes simplex virus hepatitis after liver transplantation (TID) High-dose influenza vaccine is associated with reduced mortality among older adults with breakthrough influenza (CID) Letermovir vs valganciclovir for prophylaxis of cytomegalovirus in high-risk kidney transplant recipients (JAMA) Association between combination antibiotic therapy as opposed as monotherapy and outcomes of ICU patients with pneumonia (CC) Safety of Streptococcus pyogenes vaccines (CID) Meningococcal ACWYX conjugate vaccine in 2 to 29 year olds (NEJM) Orthopaedic surgical management of pressure-ulcer related pelvic osteomyelitis (OFID) On culture and blood cultures (CMI) Benchmarking of outpatient pediatric antibiotic prescribing (JPIDS) Outbreak of suspected fungal meningitis in US patients who underwent surgical procedures under epidural anesthesia (CDC) Risk of systemic fungal infections after exposure to wildfires (The Lancet) Giardia duodenalis and dysentery in Iron Age Jerusalem (Parastiology) Community water fluoridation levels to promote effectiveness and safety in oral health (CDC) Music is by Ronald Jenkees
On episode #29 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/11 – 5/23/23. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Harmonie phase IIIb study trial results of nirsevimab against RSV lower respiratory tract infection hospitalization for infants (ESPID) Mogamulizumab for treatment of HTLV-1 associated Myelopathy/Tropical Spastic Paraparesis (IDSA) Revised protocol for secondary prevention of congenital cytomegalovirus infection with valaciclovir (IDSA) Increase in false positive fourth generation HIV tests in patients with COVID-19 (CID) Implementation of an antibiotic stewardship initiative in a large urgent care network (JAMA) Clindamycin + vancomycin versus linezolid for treatment of necrotizing soft tissue infection (OFID) Assessing empiric antimicrobial therapy with the dundee classification for skin and soft tissue infections (OFID) Combination of amoxicillin 3000mg and probenecid vs 1500mg amoxicillin monotherapy for treating syphilis in patients with HIV (CID) The sympathetic nervous system is necessary for development of CD4+ T cell memory following Staphylococcus aureus infection (JID) Efficacy and safety of sulbactam-durlobactam versus colistin for the treatment of patients with infections caused by Acinetobacter baumannii-calcoaceticu complex (The Lancet) First reported US cases of tinea caused by Trichophyton indotineae (CDC) How to use direct microscopy for diagnosing fungal infections (CMI) Limited Cutaneous Leishmaniasis as Ulcerated Verrucous Plaque on leg (EID) Can Ivermectin kill Sarcoptes scabiei during the molting process? (PLOS) The Infectious Diseases Specialist, at risk of extinction (JID) Ticks harbor and excrete chronic wasting disease prions (NIH) Music is by Ronald Jenkees
On episode #28 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/26 – 5/10/23. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Unprecedented outbreak of West Nile Virus (CDC) Approval of first RSV vaccine approved for individuals 60 years and older (FDA) FDA approves orally administered fecal microbiota product for the prevention of recurrence of C-difficile (FDA) Using thermal imaging to track cellulitis (OFID) Burden of Typhoid and Paratyphoid fever in India (NEJM) Early switch to oral antimicrobials in brain abscess (CMI) Considering vancomycin alternatives for pediatric methicillin-resistant Staphylococcus aureus bacteremia (JPIDS) Navigating treatment options for Carbapenem-Resistant Acinetobacter baumannii-calcoaceticus complex infections (CID) 2023 Duke-ISCVID criteria for infective Endocarditis (CID) Molecular characterization of Candida auris outbreak isolates in Qatar from COVID-19 patients (CMI) Amplicon sequencing reveals complex infection in infants congenitally infected with Trypanosoma cruzi (JID) Impact of Sequestration on Artemisinin-Induced Parasite Clearance in Plasmodium falciparum Malaria (CID) Advances in artificial intelligence for infectious disease surveillance (NEJM) Music is by Ronald Jenkees
On episode #27 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 4/13 – 4/25/23. Hosts: Daniel Griffin and Sara Dong Click arrow to play Download Puscast 027 (19 MB .mp3, 31 min) Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Prevalence, clinical severity, and seasonality of Adenovirus 40/41, Astrovirus, Sapovirus, and Rotavirus among children with moderate-to severe diarrhea (CID) Antibiotic-prescribing practices for management of childhood diarrhea in 3 sub-Saharan African countries (CID) Drivers of decline in diarrhea mortality (CID) Breastfeeding among people with HIV in North America (CID) Wearable sensor-based detection of Influenza in presymptomatic and asymptomatic individuals (JID) Emergence of erythromycin-resistant invasive group a Streptococcus (EID) Piperacillin-Tazobactam compared With Cefoxitin as antimicrobial prophylaxis for pancreatoduodenectomy (JAMA) VE303 for prevention of recurrent Clostridioides difficile infection (JAMA) Geographic patterns of antimicrobial susceptibilities for Bacteroides species worldwide (IJAA) Intravenous to oral antibiotic switch therapy among patients hospitalized with community-acquired pneumonia (CID) Clinical impact of syndromic molecular point-of-care testing for gastrointestinal pathogens in adults hospitalized with suspected gastroenteritis (The Lancet) Treatment of pulmonary mucormycosis with adjunctive nebulized amphotericin B (Mycoses) Giardia detection and codetection with other enteric pathogens in children in the vaccine impact on diarrhea in Africa (CID) Feasibility of training community health workers to use smartphone-attached microscopy for point-of-care visualization of soil-transmitted helminths (AJTMH) Compassionate use of bacteriophages for failed persistent infections (OFID) Music is by Ronald Jenkees
On episode #26 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 3/30 – 4/12/23. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Fatal rabies infection with failure of post-exposure prophylaxis following a zoonotic exposure (CID) Bivalent perfusion F vaccine in pregnancy to prevent RSV in infants (NEJM) Adeno-associated virus type 2 in US children with severe hepatitis (Nature) Genomic investigations of unexplained hepatitis in children (Nature) Antiretroviral treatment of HIV/AIDS during pregnancy (JAMA) Rapid PCR for respiratory viruses reduces time to result and improves clinical care (JOI) Postexposure doxycycline to prevent bacterial sexually transmitted infection (NEJM) Survey on antimicrobial resistance genes of used probiotic bacteria (EURO) Structured immune work-up in healthy children with episode of severe bacterial infection (JID) Antibiotic prescribing in U.S. nursing homes (JID) Syndromic panel testing among patients with infectious diarrhea (OFID) Early predictors of infected pancreatic necrosis in severe pancreatitis (DD) Management of nontuberculous mycobacteria in lung transplant cases (ERJ) Impact of extended-infusion piperacillin-tazobactam (Infectious Medicine) Camber Pharmaceuticals issues nationwide recall of atovaquone oral suspension due to potential Bacillus cereus contamination (FDA) Cluster of Blastomycosis among neighborhood residents (CDC) Risk factors for late-onset Pneumocystis jirovecii pneumonia in liver transplant recipients (IJID) Hyponatremia predicts cryptococcal meningitis and mortality in HIV-Positive asymptomatic individuals with cryptococcal antigenemia (OFID) Investigation of donor-derived Strongyloides stercoralis infection in multiple solid organ transplant recipients (TID) Promising new malaria vaccine for kids approved in Ghana (AP) Music is by Ronald Jenkees
On episode #25 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 3/23 – 3/29/23. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS Become a patron of Puscast! Links for this episode Blocking NS3–NS4B interaction inhibits dengue virus in non-human primates (Nature) First evidence of locally acquired Dengue infection (CDC) Respiratory viral infections in recipients of cellular therapies (OFID) Evolving Japanese encephalitis situation in Australia (JTM) Attainment of target antibiotic levels by oral treatment of left-sided infective endocarditis (CID) Utility of PCR vs serology based testing in immunocompromised patients with Bartonella (OFID) Source-associated mobile genetic elements to identify zoonotic coli infections (OneHealth) The risk of urinary tract infection in vegetarians and non-vegetarians (Nature) Hydrocortisone in severe community acquired pneumonia (NEJM) Adjunctive dexamethasone treatment in adults with Listeria monocytogenes meningitis (The Lancet) Worsening spread of Candida auris in the United States (AIM) Origin, resistance, and spread of the emerging human fungal pathogen Candida auris (PLOS) Emergence of Candida auris (mBio) Invasive aspergillosis in liver transplant recipients (Transplant ID) Trends in reported babesiosis cases (CDC) PCR assay for diagnosis of tick-borne infections in children (OFID) Molecular evidence of widespread benzimidazole drug resistance in Ancylostoma caninum (PLOS) Emphasis of diversity, equity and inclusion on U.S Adult Infectious Disease Fellowship program websites (JID) Music is by Ronald Jenkees
On episode #24 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 3/1 – 3/22/23. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Re-emergence of Parechovirus: 2017-2022 national trends of detection in CSF (OFID) Screening and testing for hepatitis B virus infection (CDC) Changing epidemiology of carbapenemases among carbapenem-Resistant Enterobacterales (OFID) Comparison of a short vs long-course antibiotic therapy for ventilator-associated pneumonia (eClinicalMedicine) The impact of timing of infectious disease consultation for Staphylococcus aureus bacteremia (CID) Intravenous doxycycline, azithromycin, or both for severe scrub typhus (NEJM) Cronobacter sakazakii infections in two infants linked to powdered infant formula and breast pump equipment (CDC) Piperacillin/tazobactam vs cefepime or carbapenems for cefoxitin-non-susceptible bacteraemia in immunocompromised patients (JAC) Positive impact of [18F) FDG-PET/CT on mortality in patients with Staphylococcus aureus bacteremia (CID) Association of antibody immunity with cryptococcal antigenemia and mortality in a South African cohort with advanced HIV (CID) Practical guide to antifungal susceptibility testing (JPIDS) Risk of COVID-19 associated pulmonary aspergillosis based on corticosteroid duration in ICU patients (OFID) Emergence and Persistence of Candida auris in Western New York with no epidemiologic links (OFID) Music is by Ronald Jenkees
On episode #23 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 2/16 – 2/28/23. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Association between cytomegalovirus infection and tuberculosis disease (JID) In-depth virological and immunological characterization of HIV-1 cure after allogeneic hematopoietic stem cell transplantation (Nature) Algorithm-based Clostridioides difficile testing as a tool for antibiotic stewardship(CMI) Clinical utility of nasal surveillance swabs in ruling-out MRSA infections in children (JPIDS) Antimicrobial for 7 or 14 days for febrile UTI in men (CID) Treatment strategy for rifampin-susceptible TB (NEJM) Current pyuria cut-offs promote inappropriate UTI diagnosis in older women (CID) Efficacy of doxycycline for mild-to-moderate community-acquired pneumonia in adults (CID) Hospitalizations for unspecified mycoses and implications for fungal disease burden estimates (OFID) Invasive mold infections following Hurricane Harvey (OFID) Cryptococcal meningitis and clinical outcomes in persons with HIV (CID) Rapid range shifts in African Anopheles mosquitoes over the last century (Biology Letters) Neuroangiostrongyliasis: Rat lungworm invades Europe (ASTMH) Balamuthia mandrillaris encephalitis presenting as a symptomatic focal hypodensityin an immunocompromised patient (OFID) Low rates of antibiotics prescribed during telehealth primary-care visits persisted during COVID19 (ICHE) Music is by Ronald Jenkees
On episode #22 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 2/2 – 2/15/23. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Influence of rapid influenza diagnostic testing on clinician decision-making for patients with acute respiratory infection (CID) Outbreak of extensively drug-resistant Pseudomonas aeruginosa (CDC) Epidemiology and clinical outcomes of non-HACEK gram-negative infective endocarditis (OFID) Azithromycin to prevent sepsis or death in women planning a vaginal birth (NEJM) Clinical significance of concomitant bacteruria in patients with Staphylococcus aureus bacteremia (EJCM) Health disparities in hemodialysis associated Staph aureus bloodstream infections (CDC) Sequential oral antibiotic in uncomplicated Staphylococcus aureus bacteremia (CMI) Genome-wide analysis of transposon mobility in the human fungal pathogen Cryptococcus deneoformans (PNAS) Prevalence of ocular candidiasis and Candida endophthalmitis in patients with candidemia (CID) Prevalence of Ocular Complications in candidemia (CID) Rapid and spontaneous post-partum clearance of Plasmodium falciparum (JID) Adoption and utilization of social media among adult and pediatric infectious diseases divisions and fellowship programs (OFID) Canine detection of chronic wasting disease in laboratory and field settings (Prion) Music is by Ronald Jenkees
On episode #21 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 1/18/23 – 2/1/23. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode The impact of cold temperature in the pattern of influenza virus infection (OFID) Janssen to discontinue Phase 3 Mosaico HIV vaccine clinical trial (JNJ) Randomized trial of vaccines for Zaire Ebola virus disease (NEJM) PD-1 blockade and lenalidomide combination therapy for Epstein-Barr virus infection (CMI) Outcomes of Daptomycin plus Ceftaroline vs alternative therapy for persistent MRSA bacteremia (IJAA) Detection of a novel strain of multidrug-non-susceptible Neisseria gonorrhoeae (The Lancet) Impact of a device to reduce blood culture contamination and false-positive central-line bloodstream infections (ICHE) Addition of anaerobic coverage for treatment of biliary tract infections (JAC) High dose Cefepime vs Carbapenems for bacteremia caused by Enterobacterales(OFID) Assessing the diagnostic performance of IGRAs for Mycobacterium tuberculosis (CID) Infective endocarditis after transcatheter aortic valve replacement (JACC) Discordant clinical and microbiological outcomes are associated with late clinical relapse in clinical trials for complicated UTIs (CID) Real-world use of bezlotoxumab and fecal microbiota transplantation for the treatment of Cdiff (OFID) Blastomycosis in New England (OFID) Management of invasive candidiasis in hematopoietic cell transplant recipients (TCT) Short course of Antifungal therapy in patients with uncomplicated Candida Bloodstream infection (OFID) Parasites and childhood stunting (Cell) Comparing complication rates of midline catheter vs. PICC line (OFID) Novel prion strain as the cause of chronic wasting disease in a moose (EID) Agreement of respiratory viruses' detection between nasopharyngeal swab and bronchoalveolar lavage in adults with pneumonia (CMI) Music is by Ronald Jenkees
On episode #20 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 1/4/23 – 1/17/23. Hosts: Daniel Griffin and Sara Dong Click arrow to play Download Puscast 019 (17 MB .mp3, 29 min) Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Neuroinvasive West Nile infection in solid organ transplant recipients (TID) Clinical markers of post-Chikungunya chronic inflammatory joint disease (PLOSNTD) Cholera outbreak in Haiti (CDC) Legionella bononiensis isolated from a hotel water in Nothern Italy (MS) Contemporary pharmacotherapies for nontuberculosis mycobacterial infections (IDT) Defining the optimal duration of therapy for hospitalized patients with UTIs and Bacteremia (CID) Fidaxomicin to prevent recurrent Clostridioides difficile (JAC) Evaluating predictive value of resected proximal bone margins in Diabetic Foot Osteomyelitis(OFID) Postoperative inflammation and fever after elective aortic valve and aortic root replacement (OFID) Fungal nomenclature: managing change is the name of the game (OFID) Clinical microbiology laboratories should use nomenclature based on current taxonomy (JCM) Race and ethnicity: risk factors for fungal infections (PLOS) Mosquito net use in early childhood and survival to adulthood in Tanzania (NEJM) Probiotic for pathogen-specific Staphylococcus aureus decolonisation in Thailand (The Lancet) Music is by Ronald Jenkees
On episode #19 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 12/22/22 – 1/3/23. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Burden of postinfectious symptoms after Acute Dengue (EID) Maribavir for CMV treatment in the real world (OFID) 24-Week all-oral regimen for Rifampin-Resistant Tuberculosis (NEJM) Beta lactam allergy association with surgical site infections (JPIDS) Effect of Macrolides on mortality in Bacteremic Pneumonia (CID) Association of repeated blood cultures with mortality in adult patients with Gram-Negative Bacilli Bacteremia (OFID) Evaluating predictive value of surgical resected proximal bone margins in Diabetic foot Osteomyelitis with clinical outcomes (OFID) Burden of serious Fungal Infections in India (OFID) Bartonella quintana transmitted by head lice (CID) Balamuthia mandrillaris Granulomatous Amoebic Encephalitis (JPIDS) Detecting Leishmania in dogs (PLOS NTD) Primer on home infusion administration methods (OFID) Biomarkers of infection or sepsis at the bedside (ICM) Implementation roadmap for establishing remote infectious disease specialist support in resource-limited settings (OFID) Perceptions and reality of antimicrobial prescribing during the transition to comfort measures (OFID) Can the future of ID escape the inertial dogma of its past? (OFID Music is by Ronald Jenkees
On episode #18 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 12/9/22 – 12/21/22. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Human Rabies in Texas, 2021 (CDC) Human rabies despite post-exposure prophylaxis (The Lancet) The Qatar FIFA World Cup 2022 and camel pageant championships increase risk of MERS-CoV transmission and global spread (The Lancet) An update on eukaryotic viruses revived from ancient permafrost (bioRx) Colistin monotherapy vs combination therapy for carbapenem-resistant organisms (NEJM) Outcomes of Ceftriaxone vs antistaphylococcal Penicillins or Cefazolin for definitive therapy of Methicillin-susceptible Staphylococcus aureus bacteremia (OFID) Salmonella enteritidis cardiovascular implantable electronic device infection (OFID) Evaluation of serotonin syndrome with Linezolid and serotonergic agents at an academic medical center (OFID) Preemptive antifungal therapy for the prevention of invasive candidiasis following gastrointestinal surgery for Intra-abdominal infections (CID) Risk factors and outcomes of invasive aspergillosis in kidney transplant recipients (CID) Predictive performance of gram staining of catheter tips for Candida catheter-related bloodstream infections (OFID) Integrative genetic manipulation of Plasmodium cynomolgireveals multidrug resistance-(JID) Clinical characteristics of patients with calcified parenchymal neurocysticercosis and perilesional edema (OFID) Impact of sequestration on artemisinin-induced parasite clearance in Plasmodium falciparum malaria in Africa (CID) Factors contributing to delayed academic advancement of women in infectious diseases (OFID) Characterization of problematic alcohol use among physicians (JAMA) Alpha-gal syndrome in the ID clinic (OFID) Efficacy and safety of Azithromycin vs placebo to treat lower respiratory tract infections associated with low procalcitonin (The Lancet) Music is by Ronald Jenkees
On episode #17 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 11/24/22 – 12/8/22. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Antiretroviral drugs for treatment and prevention of HIV infection in adults (JAMA) Outcomes of short versus long duration of antibiotic therapy for residual osteomyelitis in diabetic foot infection (Journal of Antimicrobial Chemotherapy) Rectal culture-based versus empirical antibiotic prophylaxis to prevent infectious complications in men undergoing transrectal prostate biopsy (CID) Outbreak of Burkholderia stabilis infections associated with contaminated nonsterile multiuse ultrasound gel (CDC) Factors associated with receiving longer than recommended therapy among culture-negative pulmonary tuberculosis patients (OFID) Seasonality of healthcare-associated Stenotrophomonas maltophilia (ASHE) Rezafungin versus caspofungin for treatment of candidaemia and invasive candidiasis (The Lancet) Characteristics of antifungal utilization for hospitalized children in the United States (ASHE) Cutaneous blastomycosis presenting as a nonhealing wound (NIH) Evaluation of the diagnostic accuracy and clinical utility of fungla profile (OFID) Parasitic infection increases risk-taking in a social, intermediate host carnivore (Nature) Efficacy and safety of acoziborole in patients with human African trypanosomiasis caused by Trypanosoma brucei gambiense (The Lancet) Simple nodular cutaneous Leishmaniasis caused by Autochthonous Leishmania orientalis (AJTMH) Emerging and Reemerging Infectious Diseases (NEJM) Music is by Ronald Jenkees
On episode #16 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 11/9/22 – 11/23/22. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Recommendations of the advisory committee on immunization practices for measles, mumps, rubella (CDC) Bacteremia with anaerobic bacteria and association with colorectal cancer (CID) Factors impacting the yield of image-guided biopsy in native vertebral osteomyelitis (OFID) Development of a clinical prediction score to inform tuberculosis treatment among children with HIV (OFID) First detection and molecular identification of Rickettsia massiliae, a human pathogen (PLOS) Short-course vs long-course antibiotic therapy for children with nonsevere community-acquired pneumonia (JAMA) The timing of preoperative urinary tract infection influences the risk of prosthetic joint infection following primary total hip and knee arthroplasty (JOA) Recurrent candidemia: trends and risk factors among persons residing in 4 US States (OFID) Spread of Sporothrix spp through respiratory droplets from infected cats (Medical Mycology) Comparison of mold active triazoles as primary antifungal prophylaxis in patients with newly diagnosed acute myeloid leukemia (CID) Geographic distribution of dimorphic mycoses in the United States (CID) Knowledge, experiences, and practices of women affected by female genital schistosomiasis in rural Madagascar (PLOS NTDs) Dynamic immune profile in French Toxoplasmosis patients White-Tailed deer are susceptible to the agent of classical sheep scrapie after experimental oronasal exposure (JID) The Lanzhou Brucella Leak: The largest laboratory accident in the history of Infectious Diseases (CID) Music is by Ronald Jenkees
On episode #15 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 10/27/22 – 9/9/22. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Clinical presentation and severity of adenovirus detection alone vs adenovirus co-detection with other respiratory viruses in US children (JPID) Effectiveness of different antimicrobial strategies for staphylococcal prosthetic joint infection (OFID) Clinical impact of ceftriaxone resistance in E. coli bloodstream infections (OFID) Adjunctive Gentamicin and Rifampin in staphylococcal prosthetic valve Endocarditis (OFID) Diagnostic performance of physician gestalt for bacteremia in patients in the process of being admitted with suspected infection (OFID) Effectiveness of quinolone prophylaxis in pediatric acute leukemia and hematopoietic stem cell transplantation (OFID) Risk factors for Vancomycin drug reaction with Eosinophilia and Systemic symptoms syndrome (JAMA) Prospective evaluation of the fungitell 1>3 beta-d-glucan assay as a diagnostic tool for invasive fungal disease (Wiley) Safety and efficacy of a monoclonal antibody against malaria in Mali (NEJM) Hospitalizations associated with strongyloidiasis in the United States (CID) Prophylactic benznidazole treatment fails to prevent Trypanosoma cruzi infection in dogs (PLOS NTD) Baker's dozen of top antimicrobial stewardship intervention publications for hospitalized patients (OFID) Baker's dozen of top antimicrobial stewardship intervention publications in non-hospital care settings in 2021 (OFID) Medical student debt and the US ID workforce (CID) Music is by Ronald Jenkees
On episode #14 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 10/13/22 – 10/26/22. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Relative Effectiveness of cell-based versus egg-based quadrivalent Influenza vaccines in adults (OFID) Oral is the new iv. challenging decades of Blood and Bone Infection Dogma (American Journal of Medicine) The burden of bacterial antimicrobial resistance in the WHO European region in 2019 (The Lancet) What is the appropriate dose, route and duration of antibiotic therapy for pediatric acute hematogenous osteomyelitis? (JPIDS) How generalizable are Randomized Controlled Trials in Staphylococcus aureus Bacteremia? (CID) Current treatments against mucormycosis and future directions (PLOS) The Effect of regularly dosed Acetaminophen vs no Acetaminophen on renal function in Plasmodium knowlesi Malaria (IDSA) The value of metagenomic next-generation sequencing in Leishmaniasis diagnosis (OFID) AmBisome monotherapy and combination AmBisome–Miltefosine therapy for the treatment of Visceral Leishmaniasis in patients coinfected With HIV (CID) Does Calcified Neurocysticercosis affect migraine characteristics and treatment responsiveness? (ASTMH) Association between personal ambient carbon dioxide level monitoring and incidence of Tuberculosis infection (CID) Change in the perception of oral antibiotics among medical students (OFID) Impact of antivenom administration on the evolution of cutaneous lesions in loxoscelism (PLOS) Music is by Ronald Jenkees
On episode #13 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 9/29/22 – 10/12/22. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Efficacy and safety of switching to Dolutegravir/Lamivudine versus continuing Tenofovir Alafenamide (CID) Antibiotic combinations reduce Staphylococcus aureus clearance (Nature) Cholera Vaccine: Recommendations of the advisory committee on immunization practices (CDC) Detection of Treponema pallidum DNA during early syphilis stages (CID) Association between toxoplasmosis and bipolar disorder (Journal of Psychiatry) The efficacy of soap against schistosome cercariae (PLOS NTD) Recurrent ESBL Escherichia coli urosepsis in a pediatric renal transplant patient (NIH) After action review of the response to an outbreak of Lassa fever in Sierra Leone (PLOS NTD) Music is by Ronald Jenkees
On episode #12 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 9/15/22 – 9/28/22. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Use of long-acting cabotegravir plus rilpivirine for people living with HIV-1 (HIV Medicine) Effectiveness of different antimicrobial strategies for staphylococcal prosthetic joint infection (OFID) Antibiotic Treatment Duration in Pseudomonas aeruginosa ventilator associated pneumonia (CID) Polymicrobial Foot Infection Patterns are common & associated With treatment failure (OFID) Faecal microbiota transplantation for first or second C. difficile infection (EarlyFMT) Impact of Enterococcus faecalis endocarditis treatment on risk of relapse (CID) Comparison between culture-positive and culture-negative septic shock in patients (NIH) Evaluation of serum mucorales PCR for the diagnosis of Mucormycoses (CID) Humanized transgenic mice are resistant to chronic wasting disease prions from Norwegian reindeer and moose (JID) Dentist's visits and risk of brain abscess (CID) Music is by Ronald Jenkees
On episode #11 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 9/1/22 - 9/14/22. Subscribe (free): Apple Podcasts, Google Podcasts, RSS Become a patron of Puscast! Links for this episode Post-Ebola symptoms infection (CID) Legionella identified as cause of cluster of pneumonia cases (PAHO) Frequency of exposure to antibiotics for enteropathogenic bacteria among young children (PNAS) Should Linezolid replace Clindamycin as the adjunctive antimicrobial of choice in Toxic Shock Syndrome (CID) Treatment with a three-drug regimen for Pulmonary Tuberculosis (OFID) The skip phenomenon in Staphylococcus Aureus Bacteremia (Science Direct) The relationship between antibiotic agent and mortality in patients with Febrile Neutropenia (OFID) Antibiotic indications and appropriateness in the pediatric intensive care unit (CID) Clinical features and treatment outcomes of Pulmonary Mycobacterium avium-intracellulare complex (OFID) Outcomes of partial oral antibiotic treatment for complicated S. Aureus Bacteremia in drug users (CID) Short-versus long-course antibiotic treatment for uncomplicated vancomycin-resistant enterococcal bacteraemia (CMI) Infectious Disease Consults of Pseudomonas aeruginosa bloodstream infection and impact on health outcomes (OFID) Paracoccidioidomycosis: current status and future trends (Clinical Microbiology) Comparative outcomes of Candida Auris Bloodstream Infections (CID) Efficacy and immunogenicity of R21/Matrix-M vaccine against clinical Malaria (The Lancet) Leishmaniasis: Diagnosis and Treatment in the United States (JPIDS) Malaria Surveillance — United States, 2018 (CDC) Anti-bacteriophage immunity in phage therapy (JID) Improving understanding and utilization of the antibiogram among medical residents (Cambridge) Music is by Ronald Jenkees
On episode #10 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 8/17/22 – 8/31/22. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Tomato flu outbreak (Ped Inf Dis) Rabies vaccination of dogs (PLoS NTD) Repeat revision TKR (Arch Orthopedic Trauma Surg) Cat scratch fever (Open Forum Inf Dis) Treatment of post transplant asymptomatic bacteruria (Transplant Inf Dis) Shorter antibiotic courses in immunocompromised (Clin Micro Inf) Risk of cardiovascular implantable electronic device infection (Open For Inf Dis) Diagnosis of leprosy and cerebral coenurosis (Open For Inf Dis) Enterococcus central line infection (Eur J Clin Micr Inf Dis) Treatment of otitis media (J Pediatrics) Fungal infections in US (CDC) Surveillance for fungal infections US (CDC) Cryptococcal antigenemia in AIDS (Clin Inf Dis) Intestinal parasites in medieval UK (Int J Paleopathology) Nephrotoxicity of vancomycin (Clin Inf Dis) Administration of beta-lactam before vancomycin (Clin Inf Dis) Early beta-lactam catches the germ (Clin Inf Dis) Machines that help machines help patients (Curr Clin Oncol) In-person vs telemedicine (Open For Inf Dis) Impact of COVID-19 on community hospital acquired infections (Clin Inf Dis) Music is by Ronald Jenkees
On episode #9 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 8/4/22 – 8/17/22. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Zoonotic henipavirus in febrile patients in China (NEJM) Role of prospective monitoring, pre-emptive and prophylactic therapy for human Herpesvirus-6 after stem cell transplantation (OFID) Tuberculosis outbreak in the USA linked to bone graft product (Lancet ID) Surgical and medical management of Diabetic Foot Osteomyelitis (OFID) Increase in Pediatric Intracranial Infections during COVID-19 Pandemic (CDC) Incidence of Acute Chest Syndrome in children with Sickle Cell Disease following Pneumococcal vaccine (JAMA) Antibiotic resistance genes in the gut microbiota of mothers (Nature Microbiology) Clinical characteristics, health care utilization, and outcomes among patients for Invasive Mold Disease (OFID) Low-Dose subcutaneous/intravenous Monoclonal Antibody to prevent Malaria (NEJM) Revisiting practice of the treatment of Toxoplasmic Encephalitis Phase two trial of oral fexinidazole in adults with chronic indeterminate Chagas disease (CID) Half of human pathogenic diseases can be aggravated by climate change (Nature) The Impact of standardized infectious diseases consultation on Postsplenectomy care and outcomes Potential value and patient confidentiality implications of infectious disease clinician peer consultations via social media (OFID) Music is by Ronald Jenkees
On episode #8 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 7/21/22 – 8/3/22. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Pediatric hepatitis linked to infection with two viruses (BMJ) Protection duration of Yellow Fever vaccination (CID) Impact of CSF panel on duration of treatment (OFID) Cluster of Parechovirus infections in infants (MMWR) Molecular ecology and risk factors for Escherichia coli (Journal of Antimicrobial Therapy) Melioidosis endemic in areas of the Mississippi gulf coast (CDC) Early switch from intravenous to oral antibiotics in infections (OFID) Duration of therapy and the use of Quinolone/Rifampin-Based regimens for joint infections (OFID) Efficacy of Doxycycline for mild-to-moderate community-acquired Pneumonia in adults (CID) Effectiveness of a Vancomycin dosing protocol (Cambridge Core) Outcomes of Fungemia in patients receiving extracorporeal membrane oxygenation (IDSA) Malaria transmission intensity likely modifies RTS, S/AS01 efficacy (IDSA) Ultrashort course antibiotics for suspected pneumonia (CID) Music is by Ronald Jenkees
On episode #7 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 7/7/22 – 7/20/22. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Frequent detection of monkeypox virus DNA in saliva, semen, and other clinical samples from 12 patients (Eurosurveillance) The impact of churn on HIV outcomes in the southern United States (OFID) Health Advisory: Recent Reports of PeV in the US (CDC) Cytomegalovirus viremia as risk factor for mortality in HIV-associated meningitis (International Journal of Infectious Diseases) Ghana declares its first outbreak of Marburg virus disease (BMJ) Case series of children with acute hepatitis and human adenovirus (NEJM) Pharmacokinetic variability of vancomycin in meningitis patients (Journal of Clinical Pharmacy and Therapeutics) Association of vancomycin plus piperacillin in critically ill adults (Intensive Care Medicine) Comparison of Sequential Dalbavancin to SOC treatment for bloodstream infections (OFID) Outbreak of sexually transmitted drug resistant Shigella sonnei in the UK (Lancet ID) Listeria illness and deaths associated with ongoing contamination of ice cream products (CID) Antibiotics for preventing recurrent uninary tract infections (OFID) Congenital tuberculosis after In-vitro fertilization (CID) Enhancing diagnostics in orthopedic infections (Journal of Clinical Microbiology) Screening for ocular finding among patients with candidemia (CDC) Effects of day-to-day variation of Opisthorchis viverrini antigen in urine (PLOS ONE) Disposable versus reusable medical gowns (The American Journal of Infection Control) Music by Ronald Jenkees
On episode #6 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 6/23/22 – 7/6/22. Hosts: Daniel Griffin and Sara Dong Click arrow to play Download Puscast 006 (19 MB .mp3, 31 min) Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Analysis of acute Hepatitis of unknown etiology in children aged (CDC) A contemporary review of Monkeypox for healthcare workers (IDSA) Rapid antigen test for detection of orthopoxviruses (The Lancet) Decision making regarding anal cancer screening in HIV-positive people (IDSA) Updated guidelines for testing of transplant candidates (CDC) Effect of automated telephone infectious disease consultations to nonacademic hospitals (JAMA) Prevalence and predictors of Pseudomonas aeruginosa among hospitalized patients (OFID) High yield of blood cultures in the diagnosis of cellulitis and more in elderly patients (OFID) The impact of glove and gown use on C. difficile (CID) Antibiotic therapeutic drug monitoring in critically ill patients CID) Utility of induced sputum in assessing bacterial etiology in children (JPIDS) Epidemiology of UTI infections due to Enterobacterales (OFID) Analysis of linezolid combined with methadone or buprenorphine (OFID) Management of histoplasmosis by ID physicians (OFID) Increased deaths from fungal infections during pandemic (CID) Clinical utility of antifungal susceptibility testing (JAC) Spotlight on sporothrix and sporotrichosis (Mycopathologia) Guidelines on diagnosing, preventing, and managing cryptococcal disease in HIV-positive adults and children (WHO) Dracunculiasis eradication: end stage challenges (ASTMH) Range expansion of native and invasive ticks (JID) Vaccine-hesitant moment (NEJM) FDG-PET-CT compared with CT for persistent fever in high-risk patients (The Lancet) Intro music is by Ronald Jenkees
On episode #5 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 6/8/22 – 6/22/22. Host: Daniel Griffin Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Effect of testing for respiratory pathogens on antibiotic use of children (JAMA) Outbreak of hepatitis in children (Intensive Care Medicine) Leptospirosis in retirees in rural areas (IDSA) Comparing Ceftolozane/Tazobactam to standard of care in the management of neutropenia and fever in patients with hematological malignancies (IDSA) Development of an electronic algorithm to target outpatient antimicrobial stewardship efforts for acute bronchitis and pharyngitis (IDSA) Compassionate-use of phages in twenty patients with drug-resistant mycobacterial disease (CID) Microbial Cell-Free DNA Identifies the Causative Pathogen in Infective Endocarditis (CID) The source of the Black Death in fourteenth-century central Eurasia (Nature) Noninvasive Testing and Surrogate Markers in Invasive Fungal Diseases (OFID) WHO guideline for the treatment of visceral leishmaniasis in HIV co-infected patients (WHO) Broad antimicrobial resistance in a case of relapsing babesiosis successfully treated with tafenoquine (CID) Human Filariasis in Travelers and Migrants (CID) Therapeutic hyperthermia is associated with improved survival in afebrile critically ill patients with sepsis (Critical Care Medicine) Does a school-based intervention to engage parents change opportunity for handwashing with soap at home? (PLOS NTD) Infectious diseases compensation in the USA (The Lancet) Intro music is by Ronald Jenkees
On episode #4 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 5/25/22 – 6/8/22. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Clinical features and managements of human Monkeypox (The Lancet) Clinical course and outcome of human Monkeypox in Nigeria (CID) Monkeypox outbreak report in United States – May 2022 (CDC) Travel notice for Monkeypox (CDC) Immunoglobulin-free strategy to prevent HBV mother to children transmission in Cambodia (The Lancet) CD4 T-cell depletion prevents Lassa fever associated hearing loss in mouse model Economic and clinical burden associated with infections after cell transplant (Transplant infectious disease) Multistate outbreak of Listeria monocytogenes infections linked to soft Hispanic-Style cheese – United States, 2021 (CDC) Evaluation of Mycobacterium avium complex pulmonary disease treatment completion and adherence to ATS/IDSA guidelines (NIH) Case Report: Pulmonary leptospirosis misdiagnosed as COVID-19 (ASTMH) Association of inappropriate outpatient pediatric antibiotic prescriptions with adverse drugs events (JAMA) Exploration of Primary care clinician attitudes associated with prescribing antibiotics for asymptomatic bacteriuria (JAMA) Case Report: Bartonella Quintana endocarditis in a child from Northern Manitoba, Canada Chlorhexidine and Mupirocin for Clearance of Methicillin Resistant Staphylococcus aureus Colonization After Hospital Discharge (CID) Daptomycin-Resistant Enterococcus Bacteremia Is Associated With Prior Daptomycin Use and Increased Mortality After Liver Transplantation (CID) Updated consolidated guidelines for Malaria (WHO) Podoconiosis: Clinical spectrum and microscopic presentations (PLOS) Pharmacist gender and physician acceptance of antibiotic stewardship recommendations (ICHE) Prevention of Neisseria gonorrhoeae with meningococcal B vaccine: a matched cohort study in Southern California (IDSA) Intro music is by Ronald Jenkees Send your questions for Puscast to puscast@microbe.tv
On the third episode of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 5/11/22 – 5/25/22. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Monkeypox Virus Infection in the United States and Other Non-endemic Countries—2022 (CDC) Monkeypox course (WHO) Monkeypox on TWiV 902 and TWiV Special Progress Toward Polio Eradication — Worldwide, January 2020–April 2022 (MMWR) Capsid Inhibition with Lenacapavir in Multidrug-Resistant HIV-1 Infection (NEJM) Rabies in a Dog Imported from Azerbaijan — Pennsylvania, 2021 (MMWR) Burden, clinical characteristics, risk factors, and seasonality of adenovirus 40/41 diarrhea in children in eight low-resource settings (Open For Inf Dis) Comparison of 8 vs 15 days of antibiotic therapy for Pseudomonas aeruginosaventilator-associated pneumonia in adults (Intensive Care Med) High prevalence of Pseudomonas aeruginosa carriage in residents of French and German long-term care facilities (Clin Micro Inf) Antibiotic treatment duration for community acquired pneumonia in outpatient children in high-income countries – a systematic review and meta-analysis (Clin Inf Dis) Follow-up Blood Culture Practices for Gram-Negative Bloodstream Infections in Immunocompromised Hosts at a Large Academic Medical Center (Open For Inf Dis) Meningococcal disease and immunization activities in Hajj and Umrah Pilgrimage: a review (Inf Dis Therapy) Treatment with reduced dose trimethoprim-sulfamethoxazole is effective in mild to moderate Pneumocystis jirovecii pneumonia in patients with hematologic malignancies (Clin Inf Dis) Occupational risk of cutaneous larva migrans: A case report and a systematic literature review (PLoS NTD) Quinacrine Treatment of Nitroimidazole-Refractory Giardiasis (JID) Diagnosis and management of infective endocarditis in people who inject drugs(JACC) A mechanistic model of snakebite as a zoonosis: Envenoming incidence is driven by snake ecology, socioeconomics and its impacts on snakes (PLoS NTD) Strategies to prevent central-line associated bloodstream infections in acute-care hospitals (Infection Control & Hosp Epi) Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute care hospitals (Infection Control & Hosp Epi) Use of benznidazole to treat chronic Chagas disease: An updated systematic review with a meta-analysis (PLoS NTD) Chagas Disease: The New HIV/AIDS of the Americas (PLoS NTD) Digital Strategy and Social Media in Infectious Diseases (Clin Inf Dis) Intro music is by Ronald Jenkees Send your questions for Puscast to puscast@microbe.tv
On the the second episode of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 4/27/22 – 5/11/22. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode •Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022(MMWR) •Case Series of False-Positive HIV Test Results in Pediatric Acute Lymphoblastic Leukemia Patients Following Chimeric Antigen Receptor T-Cell Therapy: Guidance on How to Avoid and Resolve Diagnostic Dilemmas (J IDSA) •Immunological correlates of prevention of the onset of seasonal H3N2 influenza (JID) •Use of a Modified Preexposure Prophylaxis Vaccination Schedule to Prevent Human Rabies: Recommendations of the Advisory Committee on Immunization Practices — United States, 2022 (MMWR) •Long-term Safety and Immunogenicity of a Tetravalent Dengue Vaccine Candidate in Children and Adults(MMWR) •The Role of C-Reactive Protein as a Triage Tool for Pulmonary Tuberculosis in Children (J PIDS) •Factors Potentially Contributing to the Contamination of Packaged Leafy Greens Implicated in the Outbreak of Salmonella Typhimurium During the Summer of 2021 (FDA) •Short-course intravenous antibiotics for young infants with urinary tract infection (Arch Dis Children) •Real-World Comparison of Bezlotoxumab to Standard of Care Therapy for Prevention of Recurrent Clostridioides difficile Infection in Patients at High Risk for Recurrence (Clin Inf Dis) •2021 Focused Update Guidelines on Management of Clostridioides difficile Infection in Adults (Clin Inf Dis) •Treatment outcomes 24 months after initiating short, all-oral bedaquiline-containing or injectable-containing rifampicin-resistant tuberculosis treatment regimens in South Africa (Lancet) •Use of Novel Strategies to Develop Guidelines for Management of Pyogenic Osteomyelitis in Adults (JAMA) •Persistent MRSA Bacteremia: Resetting the Clock for Optimal Management (Clin Inf Dis) •Frequency and Duration of, and Risk Factors for, Diagnostic Delays Associated with Histoplasmosis (J Fungi) •Intestinal parasitic infections and associated factors among people living with HIV attending Dessie Referral Hospital, Dessie town, North-east Ethiopia (AIDS Res Ther) •Association of zoonotic protozoan parasites with microplastics in seawater and implications for human and wildlife health (Nat Sci Rep) •Climate change increases cross-species viral transmission risk (Nature and TWiV 898) Intro music is by Ronald Jenkees Send your questions for Puscast to puscast@microbe.tv
On the first episode of the Infectious Disease Puscast, Daniel and Sara bring Marc Crislip's well known Puscast back to life, and present a review of the infectious disease literature for the previous two weeks, 4/13 – 4/27/22. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Rabies from an anteater (MMWR) Oral Tebipenem Pivoxil Hydrobromide in Complicated UTI (NEJM) Therapeutic monitoring of vancomycin for serious MRSA infections (IDSA) Time to retire Vancomycin for MRAS Endovascular Infections? (Op Forum Inf Dis) Impact of ID consultation on outcome of patients with enterococcal bacteremia (Op Forum Inf Dis) Effect of Gram Stain–Guided Initial Antibiotic Therapy on Clinical Response in Patients With Ventilator-Associated Pneumonia (JAMA) Effect of Antimicrobial Prophylaxis Duration on Health Care-Associated Infections After Clean Orthopedic Surgery (JAMA) Randomized Clinical Trial Comparing Seven Versus Fourteen Days of Antibiotics for Uncomplicated Gram-Negative Bloodstream Infection (Op Forum Inf Dis) Vehicle Windshield Wiper Fluid as Potential Source of Sporadic Legionnaires' Disease in Commercial Truck Drivers (MMWR) Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis (NEJM) High Prevalence of Plasmodium falciparum K13 Mutations in Rwanda Is Associated With Slow Parasite Clearance After Treatment With Artemether-Lumefantrine (JID) Association of Reduced Long-Lasting Insecticidal Net Efficacy and Pyrethroid Insecticide Resistance With Overexpression of CYP6P4, CYP6P3, and CYP6Z1 in Populations of Anopheles coluzzii From Southeast Côte d'Ivoire (J Inf Dis) Intro music is by Ronald Jenkees Send your questions for Puscast to puscast@microbe.tv