Upgrade your week in just 10 minutes with D(AI)ve Asprey’s essential rundown on what matters most in longevity, biohacking, AI health tech, and medical freedom. Each story includes trusted source links—so you can check the facts. This episode covers: - Rapamycin’s Reality Check: A sweeping new review (September 24) finds that the promise of rapamycin for longevity in healthy adults is still weak and inconsistent. Dave shares why lifestyle levers (fasting, protein timing, smart training) come first, and any rapamycin experiment should be clinician-guided and tracked with labs. Source: Aging-US press release – September 24, 2025 and EurekAlert science brief – September 24, 2025 - Senolytics Get Precise: New research (September 23) shows that not all “zombie cells” (senescent cells) are equal in how they respond to anti-aging drugs—so future protocols will be timed and typed, not one-size-fits-all. Source: Aging-US research stream – September 23, 2025 - AI Healthcare: Promise and Pause: The latest market outlook (September 23) says AI in healthcare is surging toward a $100B+ market by 2030, but 70% of doctors still want humans in the loop for diagnosis. Dave shares how to use AI as your copilot—not your captain. Source: Crescendo.ai – September 23, 2025 - Medical Policy Meets Machine Logic: A new federal pilot now lets AI approve or deny Medicare coverage, possibly cutting off therapies before a human review happens. Dave explains how to demand explainability, fair appeals, and human override to protect access. Source: KFF Health News policy rundown – September 25, 2025 - Longevity Headlines You Can Use: Forest bathing wins renewed praise for helping with blood pressure and stress. Northwestern’s SuperAger project links strong social ties to resilient brain health. Human trials now test an antibody therapy to regrow lost teeth. Source: XandroLab Longevity Roundup – Week of Sept 22–25, 2025 Action steps for the week: Try fasting windows and smart protein clustering for mTOR modulation. Let AI help summarize your health data—but get decisions confirmed by your clinician. If you or your family touch Medicare, keep thorough documentation and demand human review. Soak in green spaces, reconnect socially, and watch for cutting-edge therapies.  All source links provided for easy reference to the original reporting and research above.   This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality.  Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Rapamycin, mTOR modulation, longevity, biohacking, senolytics, zombie cells, AI healthcare, Medicare coverage, human trials, forest bathing, SuperAger, brain health, fasting, protein cycling, medical freedom, anti-aging, personalized medicine, health tech, Dave Asprey, Human Upgrade podcast Thank you to our sponsors!  LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser. KILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/ and use code DAVE for 20% off. Resources:  • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Intro 0:18 — Rapamycin Hype Check 1:07 — Senolytics Leveled Up 2:41 — AI in Healthcare 3:11 — AI Between You and Your Doctor 5:50 — Three Longevity Angles 7:59 — Outro See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Your mitochondria are the power plants of your cells, and when they break down, you lose energy, brain sharpness, and resilience against aging. In this episode, you’ll learn how to hack your mitochondria to supercharge human performance, prevent decline, and extend longevity with tools that are natural, effective, and backed by decades of research. Watch the condensed video highlight version of this episode (and much more!) on YouTube: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Catharine Arnston, founder of ENERGYbits, recent PhD graduate, and one of the world’s top experts on algae and functional medicine. Entering her 70th year without medications, with the cognition to finish a doctorate, and the health markers of someone decades younger, Catharine is living proof of how mitochondria and nutrition shape aging, brain optimization, and resilience. Together they break down why mitochondria fail after age 30, how algae works as a master supplement to restore superoxide dismutase (SOD) and glutathione, and what happens when you give your cells the nutrients they’re wired to need. They uncover how mitochondria connect to energy, inflammation, metabolism, and cellular resilience. This is a masterclass in hacking energy and longevity, built for people who want to upgrade every system of the body and mind.  You’ll learn: • Why mitochondria decline after age 30 and how to stop it • The role of superoxide dismutase (SOD) and glutathione in preventing cellular “rust” • How spirulina and chlorella outperform most supplements for detox and energy • The connection between mitochondria and brain optimization • Why men’s higher iron levels accelerate aging and how algae helps balance it • The real link between metabolism, inflammation, and longevity • How to build a mitochondria-first biohacking stack that actually works This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Catharine Arnston, mitochondria, biohacking, algae supplements, spirulina, chlorella, superoxide dismutase, SOD, glutathione, metabolism, longevity, human performance, brain optimization, functional medicine, supplements, neuroplasticity, nootropics, ketosis, fasting, cold therapy, sleep optimization, carnivore, Danger Coffee, Smarter Not Harder, Dave Asprey, Human Upgrade podcast **CTA: Go to www.energybits.com and use code ‘BEYOND’ for a 20% discount** Thank you to our sponsors!  HeartMath | Go to https://www.heartmath.com/dave to save 15% off. Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. STEMREGEN | Go to https://stemregen.co/dave25 and use code DAVE25 for 25% off your order. Resources:  • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:18 — Intro 3:03 — Longevity & Algae 8:48 — Mitochondria & ATP 13:08 — Free Radicals & SOD 13:18 — Aging After 30 17:18 — Men vs Women in Aging 24:18 — Mitochondrial Breakdown 30:03 — Algae for Mitochondria 37:18 — SOD, Glutathione & Manganese 45:18 — Algae Dosing Tips 51:18 — Processing & Quality 58:18 — Carnivore vs Plants 1:00:48 — Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Your brain isn’t as rational as you think, and that blind spot can wreck your decision-making, relationships, and even your health. In this episode, you’ll learn how to spot the hidden cognitive traps that even the smartest people fall for, and how to upgrade your thinking so you can perform better, live longer, and make choices that actually serve you. Watch the condensed video highlight version of this episode (and much more!) on YouTube: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Steven Pinker, a world-renowned cognitive psychologist, Harvard professor, and bestselling author whose research reshaped how we understand language, bias, social norms, and rationality. Pinker’s decades of scholarship make him a trusted guide to the mechanics of the mind and the behaviors that either elevate or derail human performance and longevity. Together they break down how the brain actually reasons, why smart people still fall for tribal thinking, what current AI gets wrong about human intelligence, and how “common knowledge” quietly governs cooperation, law, and civility. This is a masterclass in brain optimization through better thinking, built for people who care about biohacking, hacking mental models, neuroplasticity, and high-performance decision-making.  You’ll learn: • How to recognize and counter the “my-side bias,” even if you’re highly intelligent • Why common knowledge creates and sustains social norms and coordination • The art of indirect speech and tact, and how to calibrate your words to reduce social risk • Simple upgrades that make video calls feel closer to real eye contact and why that boosts trust • What today’s AI gets wrong about minds and why models hallucinate • Rational habits that work in the real world: steelmanning, probabilistic thinking, adversarial collaboration, and making bets as a tax on bad arguments • Why liberal democracy fits human nature better than autocracy and how norms erode or hold • How to rebuild face-to-face social skills in a screen-first culture to improve resilience and performance This is essential listening for fans of biohacking, brain optimization, human performance, neuroplasticity, and longevity who want clear, usable frameworks to think better and live better with Dave Asprey. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Steven Pinker, cognitive psychology, rational thinking, my-side bias, human nature, common knowledge, cognitive bias, AI and human intelligence, democracy and human behavior, social norms psychology, decision-making hacks, brain optimization, biohacking the mind, mental performance, neuroplasticity, rationality movement, bias and longevity, functional intelligence, Human Upgrade podcast, Dave Asprey, thinking traps, steelmanning, epistemic humility, outrage economy, psychology of power, critical thinking upgrade, hacking human performance Thank you to our sponsors!  KILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/ and use code DAVE for 20% off. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. **Order Steven’s new book WHEN EVERYONE KNOWS THAT EVERYONE KNOWS...: COMMON KNOWLEDGE AND THE MYSTERIES OF MONEY, POWER, AND EVERYDAY LIFE: HTTPS://TINYURL.COM/V685EVZR Resources:  • Steven’s Website: https://stevenpinker.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 0:59 — Introduction 1:58 — Human Nature 3:30 — Cognitive Psychology 5:46 — Academia Path 7:32 — Canada vs. U.S. 8:42 — College Value 12:08 — Curiosity 15:25 — Government & Humans 19:56 — AI & Cognition 24:45 — Fairness & Justice 32:56 — Social Norms 47:12 — Communication Skills 55:32 — Virtual Society 57:20 — Personal Biases See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

If you feel like your brain's stuck in first gear, losing focus, forgetting simple things, feeling mentally sluggish—you’re not alone. I lived with brain fog for 15 years while building companies in Silicon Valley, and no productivity hack or double espresso fixed it. In this episode, I’ll show you how to clear brain fog at the cellular level by restoring mitochondrial energy, ditching brain-damaging foods, optimizing sleep, and upgrading your nutrition. These are the exact science-backed steps that got me back to feeling sharp, focused, and fully me. Let’s turn your brain back on.Chapters:0:00 – Introduction0:49 – The Root Cause of Brain Fog1:26 – What Most People Get Wrong2:20 – How to Fix Your Mitochondria2:57 – Food: Fuel or Poison4:48 – The 4 Brain Poisons Killing Your Focus5:20 – Exercise for Brain Energy (Not Burnout)7:55 – Brain Fog Supplements That WorkBrain fog supplement: https://shopsuppgradelabs.com/products/brain-101, use code DAVE15 Connect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ and https://m.facebook.com/Thehumanupgrade/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Confidence is biology you can hack. In this episode, you’ll see how confidence builds inside your brain, rewires through neuroplasticity, and connects directly to mitochondria, metabolism, and human performance. You’ll get tools that reprogram fear, regulate your nervous system, and turn stress into fuel so you build radical confidence that lasts. Listen to this classic with host Dave Asprey as he talks with entrepreneur, author, and Women of Impact founder Lisa Bilyeu. Lisa went from a stay-at-home “supporting role” to co-founding Quest Nutrition, scaling it into a billion-dollar company, and running a global media empire. She brings years of lived experience and applied mindset training, making her one of the most authentic voices on confidence, resilience, and leadership in the biohacking world. You’ll learn how to: • Hack confidence with the same strategies you use for sleep optimization, fasting, and cold therapy • Spot biological triggers behind fear, self-doubt, and procrastination • Use repetition and mindset tools to upgrade brain optimization and neuroplasticity • Turn stress hormones into growth signals for longevity and functional medicine practices • Reframe trauma and setbacks as power for resilience and high performance • Support courage and focus with nootropics, ketosis, supplements, and Danger Coffee This episode shows you how to treat confidence as a trainable skill, not a personality trait. If you want smarter not harder strategies to master your biology, expand your impact, and live with unshakable resilience, you’ll find them here. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes release every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Lisa Bilyeu, Radical Confidence, Quest Nutrition, Women of Impact, confidence training, resilience biohacking, mindset reprogramming, courage hacking, fear rewiring, entrepreneurial mindset, human performance, brain optimization, neuroplasticity tools, mitochondria and confidence, trauma resilience, emotional regulation, nootropics for confidence, stress as fuel, leadership confidence, Human Upgrade podcast Thank you to our sponsors!  EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. Resources:  • Lisa’s Website: https://lisabilyeu.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 – Trailer 0:38 – Intro 2:38 – From Housewife to Entrepreneur 17:52 – Building Impact Theory 27:56 – Radical Confidence 39:14 – The No BS Game 44:45 – Finding Purpose 55:34 – Inner Critic & Competence 1:01:10 – Becoming Your Own Hero 1:08:32 – Boundaries & Relationships 1:09:52 – Conclusion See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

If you’ve ever cringed at the sound of your own voice or struggled to hold attention in a room, this episode will change the way you speak and how others respond to you. You’ll discover how vocal tone, breath, and emotion act as biological levers you can train to improve your health, extend your longevity, and build magnetic charisma. Watch the condensed video highlight version of this episode (and much more!) on YouTube: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Roger Love, the celebrity voice coach who trained Bradley Cooper, Tony Robbins, Selena Gomez, and Brendon Burchard. Roger has spent decades teaching actors, executives, and performers how to master their voice to create influence and impact. In this conversation, he shares the science behind vocal tone and the emotional cues hidden in your breath. You’ll hear why most people speak from the wrong part of the body and how that drains power from every interaction. You’ll learn how digital habits dull your voice, which techniques make you sound more confident and trustworthy, and why sound can heal the nervous system. Dave and Roger also explore how voice training supports your biology, boosts emotional control, and protects your performance as you age.  This episode gives you tools to speak with more authority, connect on a deeper level, and improve your health through one of your most underused systems: your voice. If you want to lead, perform, persuade, or simply feel heard, this conversation shows you how to upgrade the way you sound—and how you feel when you speak. You’ll learn: • Why most people speak from the wrong part of their body • How your voice shapes the way others feel about you • The link between vocal tone, breathing, and nervous system health • How to sound more confident, persuasive, and emotionally resonant • Why digital habits are weakening your communication • How to train your voice as a powerful analog biohack for longevity Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.  New episodes release every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Roger Love, voice coach, Bradley Cooper, vocal tone training, voice confidence, charisma training, sound healing, biohacking voice, emotional resonance, public speaking, vocal mastery, breathwork, mitochondria and voice, analog biohacking, vocal optimization, high performance communication, voice training for health, Tony Robbins voice, Human Upgrade podcast Thank you to our sponsors!  BodyGuardz | Visit https://www.bodyguardz.com/ and use code DAVE for 25% off. STEMREGEN | Go to https://stemregen.co/dave25 and use code DAVE25 for 25% off your order. Caldera + Lab | Go to https://calderalab.com/DAVE and use code DAVE at checkout for 20% off your first order.  **If you're interested in Voice Training, go to www.rogerlove.com/dave and use code DAVE for $50 off** Resources:  • Roger’s Website: www.rogerlove.com/dave • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 – Trailer• 1:30 – Intro• 1:48 – Meet Roger Love• 3:22 – Nature vs. Nurture• 5:46 – Speaking vs. Singing• 7:02 – Breathing & Voice Health• 13:35 – Voice & Attractiveness• 19:13 – Stuttering & Vocal Disorders• 24:51 – Emotional Speaking• 29:04 – Mastery & Finding Your Voice• 39:55 – Voice & Technology• 49:20 – Becoming AI-Proof• 56:29 – Emotion & Sound• 1:04:30 – Stage Fright & Tone Deafness• 1:08:00 – Voice Training TipsSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

If you’ve ever felt crushed by stress or trapped by fear, this episode gives you the science and strategies to break free. You’ll learn how Olympic-level coaching can rewire your brain for resilience, unlock peak human performance, and extend your longevity through proven biohacking tools. Watch the video highlight version of this episode (and much more!) on YouTube: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Jim Murphy, a former professional baseball player turned Olympic coach and now bestselling author of Inner Excellence. Jim has spent decades training world-class athletes and high performers to master their mindset, expand neuroplasticity, and build the courage to thrive under pressure. His work blends psychology, functional medicine, and elite coaching to help people overcome fear, reframe failure, and step into their highest potential. Together, they explore the inner game of stress mastery: why fear lives in your mitochondria, how shame and guilt sabotage performance, and how to turn setbacks into resilience. They also discuss supplements that improve metabolism, why childlike wonder fuels longevity, and how to use practical biohacking to cultivate courage. This is essential listening for anyone serious about hacking fear, upgrading resilience, and living the smarter not harder way. Whether you’re chasing athletic greatness, leading at the highest level, or just seeking more freedom in daily life, these strategies show you how to unlock love over fear and achieve lasting longevity. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing.  Keywords: inner excellence, Jim Murphy, Olympic coach, fear hacking, stress mastery, resilience training, courage mindset, shame vs guilt, brain optimization, neuroplasticity, mitochondria stress, childlike wonder, longevity habits, emotional resilience, high performance, mindset coaching, presence training, love over fear, functional medicine, stress recovery, AJ Brown, AJ Brown book, Eagles football player book, NFL sidelines book  Thank you to our sponsors!  LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser. BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order Resources:  • Jim’s Website: https://innerexcellence.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer1:30 — Intro3:10 — Subconscious Mind and Fear4:36 — Purpose Beyond Results6:38 — Writing Inner Excellence10:16 — Redefining Mental Toughness14:11 — Guilt and Shame18:24 — Embracing Fear and Challenge23:50 — Teaching Kids and Modeling Behavior31:44 — Childhood Programming and Performance45:59 — Living Fully, Ready to Die??:?? — Maintaining Childlike WonderSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most men think declining testosterone is just “part of aging”, but that’s a lie Big Pharma sold you. In this video, I break down exactly how I raised my testosterone in my 50s without injections, drugs, or TRT. These are the same biohacks I used to turn my energy, drive, and strength around, naturally. I’ll walk you through how your diet, your sleep, and even the light in your bedroom could be sabotaging your hormones. Want results? Start here.Chapters:0:00 – Introduction1:40 – The Lie About Aging and Testosterone2:49 – What’s Desatroying Your Testosterone Daily3:42 – How Your Cells Actually Make Testosterone4:58 – Why Diet is Step One (and What to Eat)7:08 – The Most Underrated T Booster8:38 – The Truth About Light and Hormones14:40 – How to Fix ItGet Your Oral Testosterone Here: http://www.LiveThrive.co/asprey Connect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ and https://m.facebook.com/Thehumanupgrade/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Want to biohack your biology with nature’s most powerful anti-aging compounds? In this episode, you’ll discover how medicinal mushrooms fuel neurogenesis, protect mitochondria, supercharge immunity, and even help save the planet’s pollinators. From sharper focus and deeper REM sleep to protecting DNA from oxidative stress, fungi are the ultimate biohacking tools for performance, resilience, and longevity. Watch episodes on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR (Re-run) Host Dave Asprey sits down with legendary mycologist and author Paul Stamets and mushroom entrepreneur Julian Mitchell. Together, they uncover the science of fungi as medicine — how mushrooms repair nerves, fight viruses, act as prebiotics for your microbiome, and provide the ultimate anti-aging biohacks. You’ll also hear how fungi hold the key to saving pollinators, regenerating soil, and extending human longevity. You’ll Learn: • Which anti-aging compounds in mushrooms protect your mitochondria and DNA • How lion’s mane stimulates nerve growth factor and improves memory, focus, and REM sleep • Why oyster mushrooms may help fight flu viruses and reduce chronic inflammation • How mushroom tinctures unlock more bioactive compounds than powders or capsules • The surprising role fungi play in saving bees and restoring environmental balance Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: anti-aging mushrooms, Paul Stamets fungi, lion’s mane memory, mushroom tincture benefits, ergothionine mitochondrial protection, oyster mushroom flu prevention, reishi immune system, cordyceps endurance, turkey tail microbiome, medicinal mushroom research, fungi save the bees, chaga antioxidants, mushroom longevity biohack, mycelium networks, functional mushrooms anti-inflammatory, mushroom brain health, neurogenesis fungi, adaptogenic mushrooms, mushroom cooking bioavailability • Lifecykel Mushroom Products - use code ‘DAVE20’ for 20% off: https://www.lifecykel.com/?rfsn=4497217.61b030&utm_source=refersion&utm_medium=affiliate&am…  • Paul Stamets’ Website: https://hostdefense.com/ Thank you to our sponsors!  • ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. Resources:  • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 — Trailer • 0:47 — Intro • 6:15 — Mushrooms vs. Algae • 10:21 — Mushroom Safety & Microbiome • 12:24 — Mushrooms as Medicine • 14:43 — Psychedelics & Microdosing • 16:26 — Kakadu Plum & Prebiotics • 18:07 — Oyster Mushrooms & Cooking • 21:35 — Mushrooms & Bees • 25:59 — Lion’s Mane & Chaga See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Want to improve memory, unlock neuroplasticity, and achieve sharper brain optimization? This episode reveals how Transcendental Meditation (TM) functions as one of the most powerful nootropics for human performance, longevity, and resilience. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with neuroscientist and physician Dr. Tony Nader, the global leader of the Transcendental Meditation movement. With an MD and PhD from MIT and Harvard, Dr. Nader bridges hard science with ancient wisdom, showing how TM measurably changes brainwaves, boosts mitochondria, and even slows biological aging. His research connects meditation to reduced stress, faster reaction time, and improved memory, giving listeners cutting-edge tools for smarter not harder living. You’ll Learn: • How Transcendental Meditation induces high-coherence alpha brain states that improve clarity, focus, and resilience • Why TM increases blood flow to the prefrontal cortex and supports memory, decision-making, and creativity • How meditation measurably reduces biological age by 5–10 years through stress reduction and physiological balance • Why reaction time and situational awareness improve immediately after meditation — even used by fighter pilots • How TM differs from mindfulness or concentration practices at the brainwave level (alpha vs. theta vs. gamma) Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: Transcendental Meditation benefits, Tony Nader MIT neuroscientist, TM brainwaves alpha coherence, Meditation and neuroplasticity, Default mode network meditation, Meditation and mitochondria, TM and biological age, Consciousness and quantum field theory, Meditation vs psychedelics, Meditation and intuition training, Meditation and dopamine, TM reaction time studies, Hippocampus meditation memory, TM and functional medicine, Meditation and metabolism, Meditation and PTSD recovery, TM for sleep optimization, Meditation and fasting stack, TM and human performance, Meditation and longevity research Thank you to our sponsors!  Business of Biohacking Summit | Apply to The Business of Biohacking Summit https://businessofbiohacking.com/.  fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources:  • Tony’s Website: https://drtonynader.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:47 — Intro 2:57 — Transcendental Meditation 3:56 — States of Consciousness 10:16 — Brainwaves & Practice 18:35 — Science Bias 38:07 — Mind & Reality 50:32 — Psychedelics & TM 54:29 — Brain & Body Effects 59:31 — Daily Practice 1:02:43 — Closing Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most people spend their lives trying to outrun death instead of learning from it. This episode shows you why facing mortality directly can unlock resilience, forgiveness, gratitude, and peace while upgrading longevity, human performance, and even brain optimization. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Suzanne O’Brien, RN—an end-of-life expert, hospice nurse, and founder of Doulagivers who has guided over 1,000 people through their final moments. She shares what the dying can teach the living about biohacking fear, letting go of unresolved trauma, and finding clarity before it’s too late. Together they explore how hacking your mindset around death transforms not only emotional well-being but also physical health, neuroplasticity, and metabolism. You’ll hear stories of people who discovered forgiveness and gratitude at the end of life, and how those practices directly influence mitochondria, sleep optimization, and longevity. They dive into the link between fear, stress chemistry, and chronic illness—and why tools like fasting, ketosis, cold therapy, supplements, nootropics, and functional medicine create the inner and outer resilience needed to face life fully. You’ll Learn: • Why fear of death silently undermines health, performance, and human potential • How forgiveness and gratitude rewire neuroplasticity and boost brain optimization • What hospice nurses know about consciousness and near-death experiences that science is only starting to confirm • How unresolved trauma shows up as physical pain and disease at the end of life Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: fear of death, hospice nurse, doulagivers, end of life planning, good death, forgiveness practice, gratitude science, near death experience, hospice care stories, emotional trauma release, spiritual awakening, conscious dying, home funeral, palliative care, death doula training, legacy planning, end of life rituals, soul agreements, dying process stages, compassionate care Thank you to our sponsors!  ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial.  BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 to save 20% off your first order of PerfectAmino.  Resources:  • Suzanne’s Website: https://suzannebobrien.com/ • Get Suzanne's Book 'The Good Death': https://thegooddeathbook.com• Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 — Trailer 01:05 — Introduction 03:13 — End-of-Life Choices 09:50 — Forgiveness & Suffering 15:46 — Advice to Younger Self 20:00 — What Makes a Good Death 23:00 — Hospice Stories & Mystical Experiences 33:05 — The Good Death Defined 41:01 — Meaning & Purpose See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if the foods you think are healthy are actually disrupting your biology? From sugar marketed as a performance tool to “whole grains” that drive cravings, this episode uncovers how hidden traps in modern nutrition can hijack your brain, wreck your metabolism, and accelerate aging. You’ll learn how to rethink daily eating so it fuels energy, resilience, and long-term health instead of quietly sabotaging it. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Max Lugavere, health journalist, filmmaker, and bestselling author of Genius Foodsand The Genius Kitchen. Max is one of the most trusted voices in nutrition and functional medicine, translating complex science into practical tools you can use right now. His work has been featured on The Today Show, PBS, and across global media for helping people reclaim health through smarter food and lifestyle choices. In this re-run, Dave and Max break down the real impact of sugar, salt, and food processing on your brain and body. They explore how cooking methods change health outcomes, when fasting and ketosis become powerful tools, and why supplements, nootropics, and trace minerals fill gaps in the modern diet. They also tackle controversial topics like carnivore diets, cold therapy, and whether “healthy” plant-based foods are truly supporting resilience—or quietly eroding it. You’ll Learn: • The biggest nutrition myths that silently damage health and performance • How sugar can act as both poison and fuel depending on context • Why cooking methods make the difference between nourishment and toxicity • The overlooked role of minerals, supplements, and culinary literacy • How nootropics, cold therapy, and sleep optimization reset your brain • Why some “health foods” accelerate aging instead of protecting you • The truth about carnivore diets, industrial farming, and sustainability • When fasting, ketosis, and carb cycling create optimal results This episode gives you a science-backed blueprint to hack your nutrition, sharpen your brain, and extend your longevity with foods that truly support your biology. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: uric acid longevity, uric acid metabolism, fructose uric acid pathway, xanthine oxidase inhibition, quercetin uric acid, luteolin supplements, AMP kinase uric acid, AMP deaminase metabolism, uric acid and mitochondria, uric acid and neuroplasticity, uric acid Alzheimer’s risk, uric acid dementia prevention, uric acid and nitric oxide, fructose metabolism hibernation biology, evolutionary mismatch uricase mutation, fructokinase inhibition, uric acid and insulin resistance, gout biohacking, uric acid and obesity, uric acid functional medicine Resources:  • Max’s Website: https://www.maxlugavere.com/ • Screenfit | Get your at-home eye training program for 40% off using code DAVE https://www.screenfit.com/dave • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 0:30 — Introduction 1:51 — Resilience & Stress 2:41 — Food Philosophy 6:20 — Sugar & Metabolism 11:21 — Fructose & Flexibility 21:57 — Big Food & Morality 24:51 — Meat & Sustainability 26:30 — Cooking at Home 28:34 — Salt & Minerals 30:07 — Dietitians & Industry 32:45 — Intuitive Eating 41:13 — Cooking Risks 45:26 — Fish & Contaminants 49:16 — Lectins & Sensitivities 52:22 — Herbs & Spices 54:59 — Recipes & Highlights 58:17 — Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most people think broccoli is a superfood, but the reality is more nuanced. In this episode of The Human Upgrade, Host Dave Asprey explores the good and bad of broccoli—why adult broccoli can block thyroid function and cause gut issues, while broccoli seeds deliver sulforaphane, the powerful compound that activates all three of your body’s detox pathways. You’ll learn how sulforaphane protects against glyphosate, repairs leaky gut, and upgrades mitochondria, metabolism, and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dave is joined by two Johns Hopkins–trained researchers whose expertise in biohacking, biochemistry, and functional medicine makes them trusted leaders in the field. Together they reveal how sulforaphane, berberine, curcumin, and alpha-lipoic acid outperform bulk vegetables and even rival GLP-1 weight loss drugs—delivering natural ways to improve metabolism, regulate dopamine, and protect the brain. Their research shows how targeted supplements can boost neuroplasticity, brain optimization, and human performance without the side effects of pharmaceuticals. Dave and his guests break down why bulk vegetables don’t deliver enough beneficial compounds, how to hack plant toxins for maximum benefit, and why supplement stacks often outperform carnivore, vegan, or high-vegetable diets for long-term health. You’ll discover how biohacking tools like fasting, ketosis, nootropics, cold therapy, and sleep optimization amplify these compounds for smarter not harder living. You’ll Learn: • Why adult broccoli can disrupt thyroid function while broccoli seeds fuel detox and longevity • How sulforaphane, berberine, curcumin, and alpha-lipoic acid support metabolism and mitochondria • Why natural compounds can rival GLP-1 drugs for weight loss and energy regulation • The connection between glyphosate, leaky gut, inflammation, and brain fog • How to stack supplements with fasting, ketosis, and cold therapy for brain optimization • Why functional medicine and biohacking provide better long-term solutions than fad diets • The smarter not harder way to extract benefits from plants without the toxic load This episode is essential for anyone serious about biohacking, upgrading metabolism, extending longevity, and achieving high performance with resilience and clarity. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: sulforaphane supplements, broccoli seed extract, detox pathways phase 1 2 3, NRF2 activation, glyphosate gut health, leaky gut repair biohacking, thyroid blockers broccoli, DIM I3C compounds, functional medicine detox, Johns Hopkins biohacking research, berberine metabolism, alpha lipoic acid mitochondria, curcumin weight loss, GLP-1 natural alternatives, dopamine metabolism regulation, neuroplasticity supplements, fasting and sulforaphane, ketosis and detox synergy, smarter not harder supplements, Dave Asprey broccoli Mara Labs Website: https://mara-labs.com/Dave for 28% off!Resources: -Mara Labs Website: https://mara-labs.com/Davefor 28% off!-BrocElite link: https://partnerships.mara-labs.com/4H6KD28/TZW7X/?&sub4=biohack&uid=123-GLPerfect link: https://partnerships.mara-labs.com/4H6KD28/TZW7X/?&sub4=biohack&uid=123Thank you to our sponsors!  EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.  Calroy | Head to https://calroy.com/dave for an exclusive discount.  Resources:  • Mara Labs Website: NEED TO INSERT CODE • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 — Trailer 01:10 — Introduction 01:49 — Broccoli Benefits & Risks 09:24 — Plant Toxins & Modern Diet 12:56 — Mold Detox Experiences 18:30 — Mycotoxins, Glyphosate & Gut Health 26:20 — Metabolic Syndrome & Endotoxins 35:44 — Timing Sulforaphane for Glyphosate Protection 39:35 — Weight Loss & GL Perfect 49:19 — Personalization & Supplement Stacking 55:10 — Sleep, Ketosis & Berberine 58:30 — Alpha Lipoic Acid + Berberine Synergy 1:01:00 — Natural Alternatives to GLP-1 Drugs See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Millions of people are living with unexplained symptoms like allergies, brain fog, anxiety, and chronic fatigue without realizing the hidden cause: mast cells gone rogue. In this episode of The Human Upgrade, Host Dave Asprey sits down with leading functional medicine physician Dr. Tania Dempsey to uncover how Mast Cell Activation Syndrome (MCAS) drives inflammation, disrupts mitochondria, and sabotages metabolism—and what you can do to switch it off. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dr. Dempsey is internationally recognized for her work in functional medicine, biohacking, and chronic illness. She co-founded the AIM Center for Personalized Medicine, has published groundbreaking research on MCAS with Dr. Lawrence Afrin, and treats some of the most complex cases of immune dysregulation, autoimmune disease, and environmental illness. Her expertise helps you understand why mast cells are the missing link in allergies, long COVID, Lyme, mold toxicity, and even hormone disruption—and how to reclaim control of your biology. Dave and Dr. Dempsey break down how mast cells interact with mitochondria, hormones, and the nervous system, showing how chronic inflammation accelerates aging and blocks human performance. You’ll discover why biohacking tools like fasting, ketosis, supplements, red light, cold therapy, sleep optimization, and smarter not harder lifestyle strategies all influence mast cell stability. They also explore why brain optimization, neuroplasticity, and nootropics are essential for calming inflammatory cascades, and how functional medicine provides practical solutions beyond conventional treatment. You’ll Learn: • Why mast cells are the hidden switch behind allergies, chronic inflammation, and brain fog • How mitochondria and mast cells work together to drive human performance—or disease • The connection between toxic mold, Lyme, long COVID, hormone imbalance, and MCAS • How supplements, fasting, ketosis, and cold therapy stabilize mast cells and boost longevity • Why functional medicine and biohacking are essential for complex chronic illness • How mast cells impact metabolism, sleep optimization, and neuroplasticity • The surprising link between mast cells, anxiety, and mental health symptoms This episode is essential for anyone serious about hacking inflammation, protecting longevity, upgrading metabolism, and achieving high performance with resilience and clarity. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: mast cell activation syndrome, MCAS, chronic inflammation, mitochondria dysfunction, histamine intolerance, functional medicine, biohacking, allergies, brain fog, long covid, mold toxicity, Bartonella, Lyme co-infections, oxalates, salicylates, mast cell stabilizers, immune dysregulation, neuroinflammation, chronic fatigue syndrome, autoimmune triggers, personalized medicine, longevity supplements Thank you to our sponsors!Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off.LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/DAVE.Resources:  • Tania’s Website: https://drtaniadempsey.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 — Trailer 01:10 — Introduction 03:27 — Why So Sick Today? 05:57 — MCAS Explained 08:33 — Mold & Environment 11:36 — Spotting MCAS 13:43 — Personal Stories 15:15 — Research & Biohacking 16:35 — Managing Triggers 20:15 — Gut & Stomach Acid 22:42 — Reaction Timing 25:30 — Hormones & MCAS 28:39 — Thyroid & Mitochondria 32:28 — Chronic Illness Navigation 40:06 — Insurance Battles 44:44 — Cholesterol & Ethics 49:11 — Personalized Care 53:24 — Circadian & Stress 58:24 — Testing Approaches 01:01:35 — Collagen & Joints 01:04:34 — MMPs & Aging 01:09:12 — Access & Experimentation 01:13:14 — MCAS & Mental Health 01:17:46 — Benzos & Stigma 01:20:23 — Vaccines & Spike Protein 01:25:18 — Research & Treatments 01:26:12 — Nicotine & Focus 01:29:24 — Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most people track glucose or ketones, but almost no one is measuring the hidden signal that could be silently wrecking your metabolism, brain function, and longevity: uric acid. This episode reveals why this overlooked biomarker drives obesity, diabetes, cardiovascular disease, Alzheimer’s, and even accelerated aging—and how you can hack it to unlock resilience, human performance, and smarter not harder health upgrades. Watch the podcast on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR We revisit host Dave Asprey sitting down with Dr. David Perlmutter, one of the world’s leading functional medicine neurologists and the #1 New York Times bestselling author of Grain Brain and Drop Acid. Dr. Perlmutter has spent decades connecting gut health, brain optimization, and neuroplasticity with lifestyle interventions that truly change the trajectory of disease. In this conversation, he explains how uric acid acts as a metabolic switch that determines whether you burn fat or store it, whether your mitochondria power you up or slow you down, and whether your brain stays sharp or declines with age. They break down how fructose, purines, alcohol, and even dehydration spike uric acid, why Japan is decades ahead in using this as a health marker, and how supplements like quercetin and luteolin rival pharmaceuticals in keeping it under control. You’ll also learn how ketosis, fasting, cold therapy, carnivore and plant-based approaches, and sleep optimization all interact with uric acid to shape your healthspan. This is biohacking at its most actionable—because once you measure this signal, you can control it, and once you control it, you radically upgrade your metabolism, your brain, and your longevity. This is essential listening for anyone serious about hacking their biology, building neuroplasticity, powering up mitochondria, exploring nootropics, and discovering smarter not harder ways to live longer and perform better. You’ll Learn: • Why uric acid may be the most important overlooked biomarker for longevity • How it connects obesity, diabetes, cardiovascular disease, and Alzheimer’s • The evolutionary reason your body uses uric acid as a survival signal • How fructose and hidden sugars sabotage metabolism and brain optimization • The role of quercetin, luteolin, and targeted supplements in lowering uric acid • Why measuring at home with a simple device can change your health trajectory • How functional medicine uses uric acid as a predictive tool for chronic disease Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: uric acid longevity, uric acid metabolism, fructose uric acid pathway, xanthine oxidase inhibition, quercetin uric acid, luteolin supplements, AMP kinase uric acid, AMP deaminase metabolism, uric acid and mitochondria, uric acid and neuroplasticity, uric acid Alzheimer’s risk, uric acid dementia prevention, uric acid and nitric oxide, fructose metabolism hibernation biology, evolutionary mismatch uricase mutation, fructokinase inhibition, uric acid and insulin resistance, gout biohacking, uric acid and obesity, uric acid functional medicine Resources:  • David’s Website: https://drperlmutter.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 0:35 — Introduction 2:26 — Why Uric Acid Matters 5:55 — Measuring Uric Acid 8:17 — Disease Risk 9:38 — Metabolism Disruption 15:59 — What Raises Uric Acid 26:20 — Global Research 29:50 — Gut & Inflammation 32:55 — Seasonal Eating 47:36 — Brain Health 56:38 — Supplements & Testing 61:45 — The LUV Diet 71:41 — Closing Insights See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Your dopamine system is being hijacked every day, and the way to reclaim it might surprise you. This episode reveals how pain, pleasure, and addiction are wired in your brain, and how to use that knowledge for real brain optimization, resilience, and longevity. You’ll discover why your dopamine levels control motivation, focus, mood, and even cravings—and the science-backed strategies that reset your neuroplasticity, metabolism, and reward system. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Anna Lembke, Stanford psychiatrist and bestselling author of Dopamine Nation. She is one of the world’s leading experts on addiction, compulsive behavior, and the neuroscience of reward pathways. With decades of clinical work and groundbreaking research, she explains why dopamine has become the modern lens for understanding desire, distraction, and dysfunction—and how we can hack it to upgrade human performance. They break down how dopamine drives addiction, why pain can reset your reward system, and how simple practices like fasting, cold therapy, and supplements affect your brain chemistry. You’ll learn how nicotine, GLP-1 drugs, and even nootropics alter dopamine sensitivity, and why overstimulation from social media, pornography, and ultra-processed food is creating an epidemic of anhedonia. The conversation also covers how functional medicine and biohacking can protect your mitochondria, restore your natural dopamine balance, and make your brain more resilient. You’ll Learn: • Why dopamine itself is not addictive—and what really drives addiction • How pain, hormesis, and “dopamine fasting” can reset your reward system • Why social media and digital overstimulation create chronic dopamine deficit states • The role of GLP-1 drugs, nicotine, psychedelics, and other substances in rewiring dopamine • How functional medicine and supplements help restore dopamine balance • The connection between dopamine, mitochondria, fasting, cold therapy, and longevity • Why radical honesty and self-binding are powerful anti-addiction hacks This is essential listening for anyone serious about hacking dopamine for better focus, sleep optimization, metabolism, and long-term brain health. Whether you’re curious about the link between dopamine and neuroplasticity, looking to upgrade human performance with smarter not harder tools, or just want to know how to stop dopamine hijacks from ruling your life, this episode gives you the science and strategies you need. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: dopamine fasting, pleasure-pain balance, dopamine deficit state, addiction neurobiology, anhedonia treatment, dopamine receptors, neuroadaptation gremlins, endogenous opioids, cold plunge dopamine, hormesis neuroscience, nucleus accumbens dopamine, L-Dopa addiction, GLP-1 and dopamine, social media addiction neuroscience, dopamine reward pathway, compulsive behavior psychiatry, dopamine and neuroplasticity, anhedonia supplements, functional medicine addiction, dopamine repair party  Thank you to our sponsors!  Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.  ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order.  Resources:  • Anna’s Website: https://www.annalembke.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:10 — Introduction 5:47 — Pleasure–Pain Balance 6:45 — Homeostasis & Adaptation 8:22 — Addiction & Dopamine Deficit 10:14 — BICEP: Conscious Pain Exposure 14:26 — Adapting to Pleasure & Pain 20:20 — GLP-1s and Joy 21:39 — Modern Anhedonia 34:32 — Resilience in Young People 42:00 — Social Media & Mental Health 44:46 — Control & Addiction 55:14 — Dopamine Fasting 1:03:18 — Self-Binding Tools 1:07:56 — Psychedelics & Addiction 1:12:25 — Parenting in the Digital Age 1:14:39 — Progress & Outlook See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Alzheimer’s is not inevitable—and it may even be optional. In this groundbreaking episode, you’ll learn how to prevent, slow, and in some cases reverse cognitive decline using strategies that also enhance brain optimization, metabolism, and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey is joined by Dr. Dale Bredesen, a world-renowned neurologist and leading Alzheimer’s researcher who has published over 240 peer-reviewed papers. Dr. Bredesen has spent decades proving that Alzheimer’s is not a one-pathway disease but a network failure driven by inflammation, toxins, and mitochondrial dysfunction. His protocol has helped thousands of patients regain memory, extend healthspan, and reclaim brain performance. Together, they unpack how biohacking tools like fasting, ketosis, supplements, sleep optimization, cold therapy, and functional medicine can rewire neuroplasticity, protect mitochondria, and keep the brain in “connection mode” instead of decline. You’ll hear why the pharmaceutical industry resists these solutions, how toxins like Paraquat and mold fuel cognitive decline, and what young people can do right now to bulletproof their brains for life. This episode is essential listening if you care about hacking human performance, upgrading metabolism, or extending longevity. You’ll walk away with practical strategies you can use today—whether that means optimizing your mitochondria with nootropics, strengthening resilience with smarter not harder recovery, or fueling your brain with Danger Coffee. You’ll Learn: • Why Alzheimer’s can begin as early as your 20s and what biomarkers to track • The seven major drivers of Alzheimer’s and how to reverse them with biohacking strategies • How APOE4 genetics, toxins, and inflammation accelerate brain aging—and what to do about it • The role of mitochondria, ketosis, and fasting in restoring brain optimization and neuroplasticity • Why prevention is exponentially easier than reversal and the top three actions you should start in your 20s • How to avoid “learned helplessness” in medicine and reclaim control over your brain span and longevity Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: Alzheimer’s prevention biohacking, APOE4 genetics risk, mitochondrial dysfunction brain, network insufficiency model, cognitive decline reversal protocol, neuroplasticity longevity strategies, mild cognitive impairment treatment, subjective cognitive impairment biomarkers, ketoflex 12/3 diet, mycotoxins and Alzheimer’s, Paraquat Parkinson’s risk, mitochondrial transfusion therapy, fasting neuroprotection, ketosis brain optimization, natokinase soft plaque removal, sleep apnea cognitive decline, functional medicine Alzheimer’s, hippocampal volume preservation, nootropics cognitive resilience, learned helplessness medicine Thank you to our sponsors!  EMR-Tek | Go to https://www.emr-tek.com/DAVE and use code DAVE for 40% off.fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE.  OneSkin | Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY. Resources:  • Dale’s Website: https://www.apollohealthco.com/dr-bredesen/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:10 — Introduction  2:43 — Personal Story 7:52 — APOE4, Genetics, and Drug Development 11:37 — Pharma, Media, and Pushback 17:13 — Prevention, Stages, and Biomarkers 23:34 — Causes and Mechanisms 30:24 — Parkinson’s, Toxins, and Mitochondria 37:17 — Longevity, Biohacking, and Protocols 44:11 — AI, Data, and Future Treatments 54:11 — Case Studies and Success Stories 1:03:00 — Detox, Mold, and Environmental Triggers 1:12:00 — Neuroplasticity and Brain Regeneration 1:20:00 — Hormones, Supplements, and Personalized Hacks 1:29:00 — Cortisol, Addison’s, and AI Protocols 1:38:00 — Large-Scale Trials and Global Impact 1:45:00 — Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Your hormones may be waging a hidden war that determines how long you live and how well you perform. This episode reveals how male and female biology diverge—and what those differences mean for your longevity, metabolism, and brain optimization. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Revisit this episode where Dave Asprey sits down with Teal Swan, a bestselling author and international speaker known for her work on human behavior, healing, and consciousness. Her insights bridge biology and psychology, uncovering how hormones, trauma, and environment shape both performance and resilience. Her ability to decode patterns of narcissism, victimhood, and trust through the lens of functional medicine and human performance makes her one of the most provocative voices in personal transformation. Together, they explore the science behind the hormonal divide between men and women—why birth control alters not just fertility but also male testosterone, why perception and neurodivergence impact neuroplasticity, and how early trauma imprints mitochondria and metabolism. You’ll learn how fasting, ketosis, cold therapy, sleep optimization, and smarter not harder strategies can shift your biology toward higher resilience and greater longevity. They also break down the biohacking tools and supplements that can help balance hormones, upgrade mitochondria, and fuel nootropics-level brain performance. From the hidden biological costs of hormonal birth control to how carnivore and targeted nutrition affect both male and female healthspan, this episode gives you a framework for hacking your biology at the deepest level. This is essential listening for anyone serious about biohacking, hacking human performance, brain optimization, functional medicine, or understanding how masculine and feminine biology directly influence lifespan and resilience. You’ll Learn: • How hormonal birth control impacts both women’s fertility and men’s testosterone • Why victim mentality rewires the brain and reduces neuroplasticity • How narcissism functions as a biological stress adaptation • The role of mitochondria, metabolism, and trauma in shaping healthspan • How fasting, ketosis, supplements, and cold therapy affect hormone balance • Why balancing male and female energetics may be a key to longevity  Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: hormone war, male vs female longevity, hormonal birth control effects, testosterone collapse, estrogen disruption, masculine vs feminine biology, victim mindset neuroscience, narcissism as adaptation, betrayal and biology, neuroplasticity and trauma, perception and neurodivergence, fractal vision, birth trauma programming, mitochondria and stress, species-level hormone imbalance, industrial hormone disruption, male fertility decline, female hormone resilience, functional medicine hormones Resources:  • Teals Website: https://tealswan.com/ • Teal’s YouTube: https://www.youtube.com/@TealSwanOfficial • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Cold Open 0:33 — Intro 2:49 — Defining Narcissism 5:48 — Gender Differences in Narcissism 7:47 — AI, Humanity, and the Future 10:25 — Extrasensory Perception & Childhood Experiences 14:04 — Birth Memories and Early Trauma 17:57 — Spiritual Abilities and Neurodivergence 22:48 — Functioning in the World with Unique Perceptions 23:45 — Trust, Support, and Creation 30:07 — Ego, Consciousness, and Spiritual Guides 33:46 — Dimensions and Multiverse Concepts 36:52 — Divine Masculine & Feminine 40:25 — Societal Imbalances and Gender Energies 46:20 — Hope for Humanity & Utopia 48:36 — Synchronization Workshops & Group Healing 51:30 — Science, Energy, and Invisible Communication 53:29 — Conclusion & Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Walking speed predicts your risk of death better than cholesterol—and this episode reveals why. You’ll learn how to test your biological age at home in just 10 seconds, and how to use that information to upgrade your human performance, extend your longevity, and tailor your biohacking strategy for maximum results. Discover the overlooked role of pelvic floor strength, glute activation, and neuromuscular training in brain optimization, metabolism, and injury prevention. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey speaks with Dr. Vonda Wright, a double board-certified orthopedic surgeon, hormone optimization expert, and elite sports medicine pioneer who’s worked with Olympic athletes, military special forces, and high-performing women through every phase of life. With decades of experience in functional medicine, movement science, and hormone therapy, Dr. Wright shares the essential strategies to prevent frailty, rebuild strength, and thrive through perimenopause and beyond. You’ll learn: • How walking speed reveals aging and longevity better than traditional blood tests • The biomechanics behind muscle “shutdown” and how to turn muscles back on • The truth about C-sections, pelvic floor rehab, and functional motion assessments • Which supplements, nootropics, and hormone therapies restore metabolism and vitality • Why perimenopause is a turning point for brain, bone, and cardiovascular health • Testing tools and training methods to upgrade strength, prevent falls, and age powerfully Whether you want to feel stronger, think sharper, or stay youthful into your 90s, this is your roadmap for smarter not harder biohacking with real-world impact. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: 10-second walk test longevity, pelvic floor dysfunction and aging, glute activation for brain health, perimenopause hormone replacement therapy, VO2 max biohacking, estrogen for bone density, neuromuscular reactivation exercises, functional movement assessment AI, post-C-section core recovery, velocity training for longevity, strength vs muscle mass aging, menopause testosterone therapy, mitochondrial health for women, sleep optimization progesterone, cold therapy for muscle recovery, fascia training for anti-aging, diastasis recti long-term effects, smart exercise hacks for aging, hormone optimization for libido and brain, smarter not harder fitness protocols Thank you to our sponsors!  Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order.  BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino.  Resources:   • Vonda's Website: https://www.drvondawright.com/ • Vonda's Instagram: https://www.instagram.com/drvondawright/?hl=en • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer1:23 — Intro2:55 — Muscle Atrophy and Reactivation6:10 — Pelvic Floor Health and Rehab8:47 — Joint Mobility and Movement10:02 — Science of Muscle Function18:23 — Perimenopause and Menolescence27:58 — Four Essential Female Hormones42:50 — VO2 Max and Longevity49:24 — Velocity Training and Bone Health62:30 — Turning Menopause into Power65:58 — Closing Thoughts and Book Rec See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Learn how to slow, and even reverse, your biological age with cutting-edge science on the molecule that controls your longevity. Host Dave Asprey sits down with Dr. Leonard Guarente, an MIT PhD and one of the most respected longevity researchers in the world, to reveal how NAD+, sirtuins, and DNA methylation clocks can help you hack aging, upgrade your mitochondria, and extend your healthspan. This episode gives you the real science, proven by over 250 studies, behind supplements, nutrition, and biohacking tools that actually work for brain optimization, metabolism, and human performance.  Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR You’ll learn why NAD+ is a master regulator of mitochondrial health, how DNA methylation clocks accurately measure biological age, and why boosting sirtuin activity improves resilience, neuroplasticity, and recovery. Dr. Guarente shares insider strategies from decades of functional medicine research, including nootropics, targeted supplements, fasting protocols, and diet adjustments from carnivore to Mediterranean that can shift your metabolism toward longevity. Dave and Dr. Guarente explore advanced biohacks like cold therapy, sleep optimization, and ketosis, plus how to balance these interventions with your genetics, lifestyle, and health goals. You’ll also hear about the surprising role of homocysteine in brain aging, how to use lab testing to guide your longevity plan, and why resilience is the ultimate measure of health. You’ll learn: • How emotional repression affects brain function, metabolism, and decision-making • Tools for nervous system regulation and emotional healing that drive high performance • Why most people fail without emotional intelligence and internal safety • How somatic awareness can optimize your energy, focus, and relationships • The science of fear, trauma release, and how to turn discomfort into growth • How to coach yourself out of stress, shame, and negative self-talk Whether you want to sharpen your brain, protect your heart, or upgrade your energy systems, this is a masterclass in smarter not harder biohacking for a longer, higher-performing life.Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: NAD+ supplementation, Sirtuin activation, DNA methylation clocks, Biological age testing, Mitochondrial biogenesis, Epigenetic reprogramming, Pterostilbene benefits, Nicotinamide riboside (NR), Nicotinamide mononucleotide (NMN), Homocysteine reduction, Oxidative stress repair, Superoxide dismutase (SOD) activation, Functional medicine longevity, Healthspan optimization, Resveratrol bioavailability, Menopause mitochondrial support, Phenylbutyrate and protein folding, High-fat diet longevity studies, Neurodegenerative disease biohacking, INCHIANTI aging study  Thank you to our sponsors!  Screenfit | Get your at-home eye training program for 40% off using code DAVE https://www.screenfit.com/dave. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.  Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources:  • Elysium Website. Use code ‘UPGRADE25’ for 25% off the first month of a monthly subscription to any Elysium supplement: https://www.elysiumhealth.com/  • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Introduction to NAD & Sirtuins 0:59 — Intro 7:04 — Animal vs Human Aging Studies 10:07 — Discovery of Sirtuins 14:43 — NAD’s Role in Aging 15:34 — Resveratrol vs Pterostilbene 23:13 — Timing NAD Supplementation 36:34 — Diet & Lifestyle Factors 50:05 — Elysium’s Basis & Signal 1:00:03 — Future Clinical Trials 1:05:14 — Psychology of Aging & Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

How do you activate your body’s natural repair system? How can you hack stem cells for faster recovery, brain optimization, and peak human performance? This episode reveals how to trigger stem cell release, direct them to the right tissues, and stack biohacking tools for maximum regeneration. You’ll learn science-backed strategies for boosting mitochondria, enhancing neuroplasticity, and extending longevity through targeted supplements, fasting, and functional medicine techniques. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey talks with Christian Drapeau, a leading stem cell scientist and founder of STEMREGEN. Christian’s decades of research have transformed our understanding of how stem cells repair the body, reverse damage, and amplify performance. He shares practical protocols to mobilize stem cells, improve microcirculation, and reduce inflammation so your body heals faster, functions better, and stays younger for longer. You’ll learn: • How stem cells rebuild muscle, brain, and organ tissue for optimal human performance • Why fasting rejuvenates bone marrow and increases stem cell effectiveness • The synergy between PEMF, vibration therapy, cold therapy, and stem cell activation • How microcirculation and inflammation control improve longevity and recovery • The best supplements and nutrients to support mitochondria and stem cell health • How to stack nootropics, ketosis, and brain optimization tools for lasting energy and focus This is essential listening for anyone serious about biohacking, longevity, human performance, mitochondria health, neuroplasticity, functional medicine, fasting protocols, supplements for recovery, brain optimization, smarter not harder healing, metabolism upgrades, cold therapy stacks, and next-level physical and cognitive resilience Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: STEMREGEN, biohacking, natural stem cell activation, human performance, longevity, mitochondria, neuroplasticity, fasting, bone marrow rejuvenation, functional medicine, supplements, brain optimization, metabolism, cold therapy, microcirculation, nootropics, ketosis, smarter not harder, recovery hacks Resources:  • STEMREGEN Website: https://www.stemregen.co/dave for 20% off your first order.  • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:00 — Why Some People Regenerate Better 1:52 — Testing Stem Cell Levels 2:58 — Natural Stem Cell Function 3:59 — Exercise & Stem Cell Response 5:13 — Tissue Turnover & Regeneration 7:03 — Bone Marrow Production 8:16 — Fasting & Bone Marrow 9:33 — Nutrition for Bone Marrow 11:14 — Traditional Meets Modern Science 12:58 — Training Bone Marrow 13:57 — Stem Cells as Repair System 34:20 — Stem Cells & Brain Injury 47:01 — Inside STEMREGEN Products 55:41 — Stress, Cortisol & Stem Cells 58:12 — Final Recommendations See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

How do you make tough decisions? How do you make them without fear or lying? This episode shows you how unresolved emotions disrupt decision-making, relationships, and functioning in peak brain performance. You’ll learn tips to rewire your nervous system for decision making, optimizing emotional intelligence, and regulating your body for high-level clarity, energy, and resilience. Discover biohacking techniques that use emotional release and somatic awareness to boost mitochondria, activate neuroplasticity, and achieve lasting personal transformation. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey talks with Joe Hudson, a world-renowned executive coach to unicorn founders and billion-dollar leaders. Joe works with a select group of top performers to unlock emotional clarity, leadership mastery, and deep personal change. His methods combine neuroscience, trauma healing, somatic therapy, and conscious coaching to help people perform at their highest level while becoming more authentic, fulfilled, and connected.You’ll learn:• How emotional repression affects brain function, metabolism, and decision-making • Tools for nervous system regulation and emotional healing that drive high performance • Why most people fail without emotional intelligence and internal safety • How somatic awareness can optimize your energy, focus, and relationships • The science of fear, trauma release, and how to turn discomfort into growth • How to coach yourself out of stress, shame, and negative self-talk This is essential listening for anyone serious about emotional intelligence, high-performance coaching, biohacking, somatic healing, trauma work, executive leadership, nervous system regulation, brain optimization, functional medicine, and building unstoppable inner resilience. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: Joe Hudson, Dave Asprey, emotional intelligence, nervous system regulation, somatic therapy, trauma healing, executive coaching, biohacking emotions, brain optimization, emotional mastery, making tough decisions, fear or failure, leadership development, negative self talk, childhood trauma, personal transformation, smarter not harder, stress relief tools, leadership listening  Thank you to our sponsors!  Puori | Head to http://puori.com/dave for 20% off, including subscriptions.  Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial.  Active Skin Repair | Visit http://activeskinrepair.com/ to learn more and use code DAVE to get 20% off your order.  Resources:  • Sign up for a complimentary transformation guide from Joe: https://www.artofaccomplishment.com/ • Joe’s Art of Accomplishment Podcast: https://open.spotify.com/show/6MjoHFfLmNgo0Msais7IJ2 • Daily Insights on Twitter: https://tinyurl.com/4kazb783 • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Introduction 2:42 — Why We Struggle with Fasting 6:28 — Identity and Control Patterns 11:56 — The Nervous System and Decision-Making 23:33 — Letting Go vs. Forcing Change 28:09 — Rebuilding Every Organ with Anti-Aging Work 33:51 — How to Actually Feel Emotions (Without Getting Stuck) 39:18 — Upgrading the Subconscious 45:02 — Final Thoughts and Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Toxins you cannot see are damaging your health, wrecking your metabolism, and quietly accelerating aging. This episode reveals how to detect the new poisons lurking in your home, how they sabotage mitochondria and brain optimization, and the biohacking fixes that restore longevity, energy, and human performance. You’ll learn actionable strategies you can implement right away, from functional medicine detox protocols to supplements that protect your nervous system and upgrade neuroplasticity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Alan Bell, an environmental health attorney and author of POISONED. Alan’s landmark legal work and decades of investigative experience have exposed some of the most dangerous everyday chemicals in modern life. After surviving his own severe toxic exposure, he’s dedicated his career to helping others identify hidden threats, fight back against corporate negligence, and restore their health through targeted biohacking and functional medicine. You’ll learn: • The most common invisible poisons in homes and how they impact metabolism, mitochondria, and brain optimization • Biohacking techniques for detox, from supplements to fasting and cold therapy • How to protect longevity and human performance with targeted functional medicine strategies • Why your sleep optimization, ketosis, and nootropics stack may fail without toxin removal • The connection between environmental toxins, neuroplasticity, and emotional resilience • How to use smarter not harder thinking to upgrade your biology for the long term This is essential listening for anyone serious about biohacking, brain optimization, hormone hacking, nootropics, functional medicine, emotional resilience, and building a state of unstoppable energy. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: Alan Bell, Dave Asprey, environmental illness, toxic building syndrome, VOC exposure, multiple chemical sensitivity, U.S. chemical safety laws, environmental toxins, mast cell activation, mitochondrial health, ten most dangerous chemicals, biohacking detox, air filtration, flame retardant-free bedding, non-toxic cookware, chronic illness  Thank you to our sponsors!  Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY.BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off.  Calroy | Head to https://calroy.com/dave for an exclusive discount.  Resources:   • Alan’s Website: https://alanbell.me/ • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:07 — Intro 3:45 — Life in a Bubble 5:40 — Building Syndrome Impact 7:04 — Legal Gaps 11:55 — Medical Blind Spots 13:04 — Chemicals + Mold 14:00 — Legal Barriers 17:15 — Environmental Disease Links 18:54 — Toxic Burden 20:53 — Media Awareness 21:55 — Hollywood Hazards 24:00 — MCS & Fibromyalgia 26:04 — Recovery Strategies 27:22 — Mast Cell Science 38:15 — Biohacking & AI 40:17 — Top 10 Chemicals 44:00 — Reduce Exposure 48:45 — Detox & Travel 50:20 — Legal + Media Power 52:33 — Chemical Industry Truth 56:19 — Policy & Advocacy 58:12 — Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Want to think faster, remember more, and rewire your brain for high performance? This special archived episode breaks down the real nootropic stack, neuroplasticity tools, and brain optimization protocols Jim Kwik uses daily, plus the biohacking routines that rebuilt his cognition after traumatic brain injury. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with world-renowned brain coach Jim Kwik, bestselling author of Limitless and advisor to billionaires, athletes, and Hollywood performers. After being labeled “the boy with the broken brain” as a child, Jim transformed his life through functional medicine, nootropics, cold therapy, neurorehab, and smart supplementation. He’s now the go-to expert on learning how to learn, with cutting-edge insights on memory, speed reading, focus, and cognitive recovery. Together, they reveal the most effective supplements for brain optimization, how to stack smart drugs with sleep optimization, the surprising downside of alpha GPC, and why things like ketosis, mitochondrial support, and even Danger Coffee are essential for modern cognition. You’ll also hear why your brain speed depends on your metabolism, the forgotten science of post-traumatic growth, and how to combine breathing, fasting, and cold therapy for massive neuroplasticity gains. Jim also shares his Brain Animal system, a new way to personalize your learning, decision-making, and communication based on your unique cognitive style. From performance to parenting, he shows how your “brain type” influences every part of life and how to hack it for focus, clarity, and flow. This episode is packed with high-impact strategies for biohacking your brain, improving human performance, upgrading memory, and building real resilience using smarter not harder protocols. You’ll Learn: • What Jim Kwik takes daily for brain speed, cognition, and mental stamina • The exact nootropics Dave Asprey uses (and the ones he avoids) • How sleep apnea nearly destroyed Jim’s performance and how he hacked it • The connection between mitochondria, memory, and metabolism • Why brain inflammation blocks focus and cognitive clarity • When to use cold therapy, hyperbaric oxygen, and stem cells for brain repair • How to know if your brain needs more acetylcholine and what happens if you overdo it • The best biohacking tools for focus, speed reading, learning, and flow state • Why your brain animal determines how you learn, lead, and connect Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keyword Index: Acetylcholine supplements, Alpha GPC vs CDP choline, Post-traumatic growth brain, Stem cells for brain repair, Hyperbaric oxygen therapy for TBI, Brain inflammation supplements, Learning disabilities recovery, Best supplements for neurogenesis, Brain fog biohacks, Brainwave training programs, Smart drug protocols, Cognitive stack routines, Mitochondrial support for cognition, Electrolytes for brain performance, Danger Coffee brain benefits, ADHD nootropics protocol, Sleep apnea and cognition, High dopamine supplements, Brain types and learning styles, Upgrade Labs review  Thank you to our sponsors!  Generation Lab | Go to http://generationlab.com/, use code Dave20 for $20 off, and see what your body’s really doing behind the surface. GOT MOLD? | Go to http://gotmold.com/shop and use DAVE10 to save 10% and see what’s in your air. BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 to save 20% off your first order of PerfectAmino.  Resources:  • Jim's Website: https://www.jimkwik.com/ • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 — Introduction & Brain Health • 0:47 — Childhood Injury & Struggles • 2:53 — Adversity & Purpose • 6:31 — Nootropics & Optimization • 18:49 — Daily Biohacking Habits • 32:14 — Exercise & Brain Function • 34:21 — Learning & Cognition • 38:06 — Sleep & Resilience • 41:41 — Brain Types Explained • 52:16 — Parenting & Neuroplasticity • 57:19 — Limitless Update & Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if the most powerful upgrades for brain energy, metabolism, and drive aren’t in mainstream medicine, but in rare peptides and misunderstood hormones? In this episode, you’ll discover the cutting-edge compounds, nootropics, and hormonal strategies that elite biohackers are using right now to optimize every part of their biology. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Jay Campbell and Hunter Williams, co-founders of BioLongevity Labs—a performance biotech company creating oral peptide-based products like BioMind and BioGutPro. Jay is a globally recognized expert in testosterone optimization, author of The TOT Bible, and a leading voice in hormone and peptide therapeutics. Hunter is a high-performance coach and podcast host focused on metabolism, mindset, and men’s health through functional medicine and advanced supplementation. In this high-energy, high-clarity conversation, the trio explore what’s working right now in advanced human performance, spanning hormone synergy, mitochondrial enhancement, libido compounds, nootropics, and muscle-preserving stacks. You’ll hear why Dave injects estradiol three times per week, how Jay and Hunter use oral bioregulators to improve gut-brain signaling, and what peptides are quietly reshaping the future of health.  You’ll Learn: • Who should use estradiol—and how it can protect brain performance in men • The real role of testosterone and estradiol synergy in male health and longevity • How BioLongevity Labs is innovating with oral peptide delivery for cognitive and gut health • Why peptides like BPC‑157, TB‑500, PT‑141, and SS‑31 are changing mitochondrial care • The truth about Melanotan‑1, SLU, AOD‑9604, GW‑501516, and BAM‑15 • What makes BioMind and BioGutPro different from standard nootropic or probiotic stacks • Why libido and metabolic health are deeply connected • The dangers of unvetted peptide sources—and what to look for in quality and bioavailability This is essential listening for anyone serious about biohacking, hormone optimization, mitochondrial support, brain energy, nootropics, neuroplasticity, functional medicine, sleep optimization, metabolism, and smarter-not-harder living. Keyword Index: estradiol for men, Dave Asprey hormone therapy, Jay Campbell BioLongevity Labs, Hunter Williams performance coaching, BPC‑157 recovery peptide, TB‑500 tissue regeneration, PT‑141 libido peptide, SS‑31 mitochondria peptide, Melanotan‑1 for skin and mitochondria, SLU stack, AOD‑9604 fat loss peptide, GW‑501516 Cardarine, BAM‑15 mitochondrial uncoupler, oral peptide delivery, BioMind brain supplement, BioGutPro gut-brain axis, testosterone estradiol synergy, mitochondrial uncoupling, nootropic peptide stacks, performance biohacking supplements Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing.  Thank you to our sponsors!  Puori | Head to http://puori.com/dave for 20% off, including subscriptions.  Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off.  ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order.  Resources:  • BioLongevity Labs Website: https://biolongevitylabs.com/?ref=DAVE# • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 – Trailer 01:00 – Introduction & Early Days of Biohacking 02:03 – Peptides 101: Foundations and Frameworks 03:06 – Peptides for Healing, Cognition, and Longevity 07:56 – Bioregulators and Russian Innovations 11:07 – Side Effects and Safety of Peptides 22:27 – Oral Peptides and Product Innovations 27:41 – Body Composition, Hormones, and Fat Loss 32:02 – Testosterone, Estrogen, and Male Health Protocols 45:03 – Peptides for Performance, Fat Loss, and Longevity 1:26:32 – Loose Skin, Surgery, and Body Transformation 1:38:00 – Closing Thoughts & Product Recommendations See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ready to learn about the secret compounds, molecules, nootropics, and stacks that Big Pharma doesn’t want you to know about? This episode is packed with the exact dopamine-boosting compounds, stacks, and biohacking protocols that top performers are using to supercharge human performance, brain optimization, and long-term resilience. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Lucas Aoun, Australia’s leading biohacker and founder of Ergogenic Health. Known for his fearless, data-driven experimentation, Lucas specializes in nootropics, dopamine modulation, mitochondria, and functional medicine. He’s spent over a decade testing underground compounds, natural molecules, and hormone-based strategies to achieve elite-level brain and body performance. Together, they explore Russian-developed enhancers like Bromantane and ITPP, and reveal how these rare compounds impact dopamine regulation, neuroplasticity, and mental drive. You’ll learn how to upregulate tyrosine hydroxylase (your brain’s dopamine switch), build targeted stacks for motivation and confidence, and avoid the common supplements that quietly kill your ambition. They also dive into the connection between dopamine and testosterone, explaining how to rewire hormonal feedback loops to reclaim masculinity, energy, and purpose. From libido hacks and prolactin suppression to stacking dopamine with GABA and acetylcholine, this episode gives you a complete system for motivation mastery. Other key topics include the dangers of chronic ashwagandha use, sleep optimization for dopamine recovery, the truth about adaptogens and cold therapy, ketosis, fasting, DHT science, ciproheptadine microdosing, and why mitochondrial support is essential for long-term performance and metabolism. You’ll Learn: • The #1 Russian compound for explosive dopamine and drive • Why most “calming” supplements destroy your ambition • How dopamine and DHT shape masculinity and performance • Advanced biohacks for sleep, motivation, libido, and mood • The truth about serotonin dominance and how to escape it • Which functional medicine tools enhance brain energy and metabolism • How to build your own dopamine protocol using proven nootropics • Why mitochondrial health is the hidden key to motivation and mood This is essential listening for anyone serious about biohacking, brain optimization, hormone hacking, nootropics, functional medicine, emotional resilience, and building a state of unstoppable energy. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing.  Thank you to our sponsors!  OneSkin | Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY.  Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.  LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/DAVE.  Resources:  • Lucas’s Website: https://www.boostyourbiology.com/ • Lucas’s YouTube: https://www.youtube.com/c/boostyourbiology • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Tags:  dopamine boosters, russian nootropics, bromantane benefits, biohacking dopamine, boost motivation naturally, dopamine stack, lucas aoun podcast, dave asprey dopamine, nootropics for energy, secret russian compounds, brain optimization, biohacking supplements, increase dopamine levels, functional medicine hacks, hormone optimization, dopamine and testosterone, neuroplasticity hacks, superhuman energy, underground nootropics, dopamine protocols See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Getting 50 grams of protein per meal may be the single most underrated biohacking protein strategy for muscle growth, metabolism, and longevity. In this episode, you’ll discover why animal protein vs vegan is not a fair match biologically, how hitting the leucine threshold activates mTOR for longevity, and why muscle is the most overlooked organ of aging. This is must-listen content for anyone optimizing human performance, hacking metabolism, or reversing muscle loss with food. Host Dave Asprey is joined by Dr. Gabrielle Lyon, a pioneer in Muscle-Centric Medicine®, functional medicine expert, and top authority on clinical nutrition for longevity. Trained by protein researcher Dr. Donald Layman, she brings decades of expertise on how to use high-protein diets, amino acid science, and functional medicine to radically improve healthspan and brain optimization. Dr. Lyon works with everyone from special operators to aging patients, making her one of the most trusted voices in anti-aging diet strategies. Watch this channel on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR You’ll learn: • Why 50g of protein per meal matters more than total daily intake • How mTOR and longevity are misunderstood in mainstream nutrition • Why protein vs plant protein debates ignore hard biological data • How leucine thresholds determine muscle activation • Why fasting and protein cycling beats low-protein veganism • How ketosis and protein intake impact metabolic health • Why many on a vegan diet experience sleep issues, hormone crashes, and reduced resilience • How functional medicine podcasts like this one reveal the truth about aging and muscle loss • What happens clinically when patients switch to a high-protein diet • How to use supplements, nootropics, and protein hacks to enhance neuroplasticity, mitochondrial energy, and total body performance If you’ve ever asked “what’s the best protein for muscle growth?” or “how does protein affect metabolism in aging?”, this episode gives you evidence-based answers from the front lines of clinical nutrition. This channel is a must-listen for anyone serious about hacking their biology, upgrading cognitive performance, and using unconventional tools to create lasting transformation. Whether you’re tracking HRV, optimizing for deep sleep, or working toward metabolic resilience, these conversations deliver insights you won’t hear anywhere else.  Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living.  Episodes are released every Tuesday, Thursday, and Friday where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing.  Thank you to our sponsors!  40 Years of Zen | Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE.  Lumiram | Go to http://healthlighting.com/dave to save 10% on your order.  Resources:   • Gabrielle’s Website: https://drgabriellelyon.com/ • Gabrielle’s IG: https://www.instagram.com/drgabriellelyon/ • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com  Timestamps: • 0:00 Trailer • 0:51 Protein Controversy  • 2:38 Leucine • 6:00 mTOR, Methionine, and Protein Synthesis • 9:00 Vegan vs. Carnivore • 16:00 Optimizing Protein Intake & Aging • 22:00 Carbohydrates, Hormones, and Female Health • 28:00 Environmental Impact & Food Sourcing • 34:00 Debunking Plant-Based Documentaries • 40:00 Key Takeaways & Closing Keywords: protein vs plant protein, 50 grams of protein, biohacking protein, mTOR and longevity, animal protein vs vegan, leucine threshold, Gabrielle Lyon, muscle-centric medicine, best protein for muscle growth, anti-aging diet, muscle as organ of longevity, fasting and protein, ketosis and protein, vegan diet risks, optimizing metabolism, high-protein diet, functional medicine podcast, Dave Asprey protein, aging and muscle loss, clinical nutrition for longevity See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This episode reveals how military-grade sound frequencies can rapidly shift your mental state, enhance neuroplasticity, and accelerate brain optimization. You’ll learn how to hack your nervous system using real-time biometric data, how frequency compositions are changing functional medicine, and why sound is emerging as one of the most powerful tools for human performance and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey is joined by Rev. Michael Beckwith, founder of the internationally renowned Agape International Spiritual Center and one of the most respected voices in spiritual transformation and human potential. With over four decades of teaching, Michael has impacted millions through his work in consciousness, meditation, and high-performance inner development. Joining him is Henry Penix, founder of SOAAK Technologies, a cutting-edge frequency healing platform trusted by clinicians, elite performers, and even the US Air Force. Together, they explore how sound can rewire brainwaves, reduce anxiety, support sleep optimization, and create measurable changes in metabolism, mood, and mindset.  You’ll learn: • How the Air Force is using frequency tech to support mental recovery and cognitive performance • What makes SOAAK’s custom sound compositions biologically effective • How sound impacts mitochondria, mood, and brainwave coherence • The link between sound healing, neuroplasticity, and high-performance states • Why hydration, supplements, and biohacking stacks boost sound-based protocols • The surprising connection between prayer, frequency, and emotional regulation • How to integrate sound biohacks with fasting, ketosis, sleep tools, and nootropics • Why this tech pairs with cold therapy, Danger Coffee, and smarter not harder principles This channel is a must-listen for anyone serious about hacking their biology, upgrading cognitive performance, and using unconventional tools to create lasting transformation. Whether you’re tracking HRV, optimizing for deep sleep, or working toward metabolic resilience, these conversations deliver insights you won’t hear anywhere else.  Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing.  Thank you to our sponsors!  Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off.  Active Skin Repair | Visit http://activeskinrepair.com/ to learn more and use code DAVE to get 20% off your order.  ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order  Resources:  • SOAAK Website: https://www.soaak.com/dave • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 — Trailer • 1:00 — Intro • 2:42 — Humor & Frequency • 5:20 — Soak App Origins • 8:15 — Biometrics & Sound Delivery • 10:40 — Inner Alignment & Brain Mapping • 13:46 — Beckwith’s Results • 19:44 — Sound & Biohacking • 23:32 — Mood & Sleep Shifts • 24:53 — Supplements & Water Synergy • 26:25 — Emotional Congruence • 29:49 — Frequency & Sexuality • 32:43 — Military & Medicine • 35:32 — Light, Sound & Quantum Effects • 40:34 — Analog vs. Digital Sound • 48:45 — Spiritual Experiences • 53:14 — Conclusion & CTA See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

You’ve been lied to about how long it takes to change a habit. This episode reveals a powerful, science-backed method to rewire your brain in just 63 seconds—without relying on willpower. You’ll discover how to use the 63-second window to interrupt destructive thought loops and how true habit change requires 63-day habit formation, not the popularized 21-day myth. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Caroline Leaf, a cognitive neuroscientist and best-selling author known for her groundbreaking work on the mind-brain connection. With over four decades of experience, Dr. Leaf has helped millions better understand the differences between the mind vs brain, how to harness intuition and neurobiology, and how to apply science-based tools for healing trauma with neuroscience. Her newest work, Help in a Hurry, builds on her bestselling book Cleaning Up Your Mental Mess, offering real-time tools to regain mental control during moments of emotional chaos.  You’ll learn: • Why the 21-day habit myth persists and what the neuroscience actually shows • How to use the 63-second window to stop toxic thoughts from wiring into your brain • What happens during the 63-day habit formation cycle and how to stay on track • The difference between the subconscious vs unconscious mind • How to rewire your brain for better emotional regulation and decision-making • The power of forgiveness and how it relates to quantum entanglement • Caroline Leaf’s mental mess strategies to overcome triggers in real time • Why the free will neuroscience debate matters for your mental sovereignty • How to interpret intuitive “blips” through a neuroscience lens • Tools for using neuroplasticity to heal trauma, manage emotions, and boost clarity This episode is a must-listen for anyone interested in brain optimization, biohacking, human performance, mental resilience, and smarter-not-harder strategies for personal growth. Whether you’re focused on fasting, cold therapy, nootropics, sleep optimization, or upgrading your mitochondria, these mental frameworks will amplify your results.  Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living.  Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Thank you to our sponsors!  Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order IGNITON | Go to https://www.igniton.com/DAVE and use code DAVE to save 15%. Resources:  • Order Caroline’s New Book ‘Help in a Hurry’ - https://a.co/d/6O9RaJB • Caroline's Website: https://drleaf.com/ • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com  Timestamps: • 0:00 Trailer • 0:54 Intro • 1:12 63-Second Habit Rule • 5:14 21 vs 63 Days • 9:20 Habits vs Trauma • 14:19 Healing & Spiritual Insight • 17:43 Free Will & Mind-Brain Link • 19:11 Conscious vs Subconscious • 26:02 Intuition & Memory • 33:15 AI & Consciousness • 37:56 Death & Energy • 51:21 Forgiveness & Entanglement • 55:14 Self-Regulation Tools See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What is Herbal Ecstasy—and why does it matter? This might be one of the most insane episodes we’ve ever recorded, and we had to bring it back because the story is too wild, too relevant, and too packed with real lessons in biohacking, brain optimization, and supplement hacking to miss. Host Dave Asprey sits down with Shaahin Cheyene, the renegade teenage entrepreneur who built a billion-dollar supplement empire before he could legally drink. As the creator of Herbal Ecstasy, Shaahin hacked natural compounds into high-performance nootropics that boosted energy, neuroplasticity, and metabolism—long before biohacking was a movement. He faced seven federal investigations, never spent a day in jail, and went on to pioneer the vaporizer industry and dominate Amazon with advanced supplement marketing.  This episode explores how Shaahin reverse-engineered functional medicine principles, used ancient plant medicine to upgrade human performance, and scaled a controversial brand using raw hustle and hacking tactics. You’ll hear how Herbal Ecstasy worked, why it was banned, and what it teaches us about supplements, mitochondrial function, dopamine regulation, and the dark politics behind wellness innovation.  You’ll learn: • Why Herbal Ecstasy became a billion-dollar underground supplement • How Shaahin used nootropics and adaptogens to hack energy, focus, and neuroplasticity • What his clash with the FDA reveals about supplement regulation and functional medicine • How dopamine, mitochondria, and metabolism drive human performance • The difference between hacking systems vs conforming to broken ones • How storytelling, podcasting, and controversial supplements build legacy brands Whether you’re optimizing your sleep, hacking your brain, experimenting with ketosis or fasting, or upgrading your stack with supplements that actually work—this channel delivers strategies, cautionary tales, and insight you won’t find anywhere else. lt is essential listening for anyone serious about biohacking, brain optimization, supplements, mitochondria, metabolism, functional medicine, nootropics, longevity, dopamine, cold therapy, sleep optimization, emotional regulation, neuroplasticity, fasting, podcasting, RFK-era health freedom, ketosis, entrepreneurship, and building influence smarter not harder—with or without Danger Coffee. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Thank you to our sponsors!  Resources:  • Shaahin’s Website: https://www.shaahincheyenne.com/ • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 — Trailer • 0:45 — Intro and guest setup • 4:39 — Escaping Iran and early hustle • 8:26 — Birth of Herbal Ecstasy • 14:21 — Explosive growth and legal heat • 25:06 — Lessons on money and business • 31:17 — Inventing the digital vaporizer • 40:03 — Hacking success on Amazon • 41:59 — Nootropics and the Limitless pill • 46:38 — Martial arts and mental resilience • 55:44 — Podcasting, media, and influence • 1:07:09 — Where to find Shaahin and closing thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

You’re leaving brainpower on the table, and this episode shows you how to reclaim it. Learn how to boost cognitive performance by 25% without relying on pills, stimulants, or gimmicks. Host Dave Asprey sits down with global finance expert and cross-cultural thinker Richard Conrad to explore how your cultural programming shapes your biology, metabolism, neuroplasticity, and even your ability to reach peak human performance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Richard is the author of Culture Hacks and has spent over 30 years living and working across Japan, China, and the U.S. He’s a master of decoding hidden mental frameworks that influence perception, longevity, and decision-making. This is a must-listen if you care about brain optimization, functional medicine, and living smarter, not harder. Together, they break down why different cultures process truth, time, and identity so differently and how these filters influence your beliefs about supplements, fasting, cold therapy, sleep optimization, and more. You’ll also learn why Americans are biologically wired for linear logic, how agrarian versus warrior cultures shaped meditation and nervous system regulation, and how to train your mitochondria to perform like a samurai’s. You’ll Learn: • Why your culture shapes how your brain processes reality • How to shift from linear to systems thinking for better neuroplasticity • The connection between meditation styles, nervous system wiring, and mitochondria • How to apply ancient frameworks to modern biohacking and human performance • Why longevity without financial planning is a broken strategy • How to avoid cognitive bias by decoding relative versus absolute truth This channel is packed with biohacking wisdom, from nootropics and ketosis to Danger Coffee, financial resilience, and how your beliefs about aging could be accelerating it. Whether you’re focused on hacking your brain, upgrading your metabolism, or extending your longevity, this is one of the most unique mind-expanding channels around. It is essential listening for anyone passionate about biohacking longevity, functional aging, mitochondrial testing, and next-gen human optimization. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Thank you to our sponsors!  Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial.  OneSkin | Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY. Generation Lab | Go to https://generationlab.com/, use code DAVE20 for $20 off, and see what your body’s really doing behind the surface. Resources:  • Order Richard’s Book “Culture Hacks”: https://a.co/d/9122Q25 • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:10 Intro • 03:15 Middle East Perception Gap • 06:53 China’s Strategy & Trade • 09:53 Japan vs China Mindsets • 14:28 Logic: East vs West • 18:23 Cultural Tools for Life • 24:23 Global Population Crash • 30:18 Shifting Economic Power • 55:33 Smart Finance Principles • 01:09:28 Real Estate & Policy See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This may be the most cutting-edge life extension technology you’ll hear about for decades. You’ll discover how mitochondrial transfusion, rejuvenation, and repair could reverse biological aging, supercharge your metabolism, and radically extend healthspan—all by upgrading the cellular energy systems that power every function in your body. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with inventor and tech entrepreneur Tom Benson, founder of Mitrix. After launching three successful Silicon Valley companies, Benson shifted focus to one of the most promising frontiers in science: mitochondrial bioreactors designed to regrow your own autologous mitochondria. This isn’t theory—it’s a near-future anti-aging technology poised to transform functional medicine, personalized medicine, and the global conversation around aging reversal. They explore how mitochondrial DNA mismatches affect aging, why mitochondria act like cellular AI cores, and how dysfunction in these ancient organelles contributes to neurodegenerative disease, metabolic decline, and cognitive disorders. You’ll learn how restoring mitochondria could enhance everything from stem cell therapy and nootropics to ketosis, fasting, cold therapy, and even sleep optimization.  You’ll Learn: • Why mitochondria may be the real control centers of human biology • How mitochondrial transfusion could revolutionize longevity and functional medicine • The connection between mitochondrial dysfunction and Parkinson’s, autism, and ALS • Why brain optimization and neuroplasticity depend on cellular energy • How stem cell-derived mitochondria compare to nootropics and NAD • What happens when mitochondrial DNA and nuclear DNA are mismatched • Why early aging might start with your egg cells’ mitochondrial computing • How mitochondrial health influences metabolism, ketosis, and fat storage • Why stress, toxins, and pharmaceuticals like statins wreck mitochondrial function • What it takes to scale mitochondrial bioreactors for widespread human use • How mitochondrial hacking could improve immune function, sleep, and resilience • Why the future of biohacking might begin with testing and upgrading your mitochondria This episode is essential listening for anyone passionate about biohacking longevity, functional aging, mitochondrial testing, and next-gen human optimization. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Thank you to our sponsors!  -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order.  -Active Skin Repair | Visit http://activeskinrepair.com/ to learn more and use code DAVE to get 20% off your order.  Resources:  • Mitrix Website: https://www.mitrix.bio/ • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:42 Intro • 04:33 Mitochondrial DNA & Performance • 08:49 Challenges in Mitochondrial Therapy • 13:31 Future Applications • 19:07 Mitochondria & Longevity • 20:19 Traditional Medicine • 28:50 Space Exploration • 29:35 Human Fragility • 30:19 Aging Revisited • 32:52 Experimental Research • 36:04 Ethics & Risks • 41:24 Mental Health Links • 46:28 Treatment Breakthroughs • 51:01 Personal Longevity Hacks • 54:30 Wrap-Up & Contact See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if one spray could upgrade your brain, protect your mitochondria, and outperform IV therapy and liposomal supplements? In this episode, you’ll discover the breakthrough science behind topical glutathione delivery that uses your skin’s water channels to raise intracellular glutathione levels in just 60 seconds. Learn how this powerful antioxidant works at the cellular level to reduce oxidative stress, support mitochondrial function, and drive real improvements in brain health, emotional resilience, and human performance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Nayan Patel, a world-leading pharmacist and formulator who pioneered this next-gen delivery method. With over two decades of clinical work in functional medicine, Nayan has helped reshape how we think about glutathione benefits, systemic detox, and performance optimization. His research shows that topical delivery bypasses traditional fat-based absorption, achieving higher brain uptake and faster results than IVs or capsules.  You’ll learn: • Why glutathione for longevity is foundational to biohacking • How it protects against cellular inflammation and improves TBI recovery issues • Why pairing glutathione with NAD+, vitamin C, or pharmaceutical nicotine creates a powerful synergy • How it preserves NAD+, supports sirtuins, and enhances ATP production • When to use glutathione as an immune booster for resilience and recovery This conversation also reveals the truth behind liposomal supplements, how your age affects glutathione absorption, and why this molecule is critical for anyone using nootropics, in ketosis, or pushing metabolic limits. This episode is essential listening for anyone into biohacking, cold therapy, functional medicine, or RFK-style medical freedom. You’ll walk away with practical tools to boost nitric oxide naturally, prevent dysfunction, and optimize your biology whether you’re on a carnivore diet or just looking for an edge.  Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing.  Resources:  • Auro Wellness Website: Use code ‘dave10’ at checkout https://aurowellness.com/ • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com  Timestamps: • 00:00 Trailer • 00:20 Intro • 01:12 Water Channel Delivery Explained • 02:25 What Makes Glutathione Special • 05:04 Why IVs and Liposomes Fail • 06:29 Measuring Glutathione in the Brain • 10:42 Key Benefits and Use Cases • 20:49 Emotional Resilience Effects • 23:54 Sensitivity and Response • 24:55 Best Timing for Use • 25:53 Workout Performance Boost • 26:47 Brain Health and TBI Support • 28:22 Best Stack Combinations • 29:32 Nicotine + Glutathione Synergy • 33:18 Longevity, Sirtuins, and Genes • 40:36 Glutathione as Immune Booster • 43:15 Peptides and Next-Gen Hacks • 45:29 Dosing Tips and Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

If you care about longevity, brain optimization, sexual performance, or metabolism, this molecule changes everything. Host Dave Asprey sits down with nitric oxide pioneer Dr. Nathan Bryan to reveal why this overlooked molecule controls your blood flow, mitochondrial energy, neuroplasticity, insulin response, and even your libido. You’ll learn how nitric oxide acts as a master switch for human performance and why the medical system has ignored it for decades. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dr. Nathan Bryan is a world-renowned expert in nitric oxide biochemistry with over 20 years of clinical research, multiple patents, and collaborations with Nobel Prize-winning scientists. His groundbreaking work forms the foundation for modern functional medicine protocols targeting blood flow, metabolism, cognitive enhancement, and mitochondrial upgrades. You’ll learn: • How nitric oxide drives mitochondria, metabolism, and human performance • Why most nitric oxide supplements fail and how to spot real ones • The critical role nitric oxide plays in brain optimization, libido, and insulin signaling • How poor oral health, statins, and PPIs can kill nitric oxide production • What nitric oxide has to do with sleep optimization, aging, and disease prevention • How to stack nitric oxide with fasting, ketosis, nootropics, red light, and supplements • Why “Smarter Not Harder” starts with nitric oxide fueled upgrades This episode is essential listening for anyone into biohacking, cold therapy, functional medicine, or RFK-style medical freedom. You’ll walk away with practical tools to boost nitric oxide naturally, prevent dysfunction, and optimize your biology whether you’re on a carnivore diet or just looking for an edge. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Get Nitric Oxide products for 10% off with code ‘Dave’: https://bit.ly/Nitric-Oxide-Product SPONSORS: Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources:  • Nathan’s Website: https://www.n1o1.com • Nathan’s YouTube: https://www.youtube.com/channel/UCtftGy8e0r9DO8ActcyGi4w • Dave Asprey’s Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:03 Intro • 01:15 Why Medicine Ignores Nitric Oxide • 01:59 What Nitric Oxide Does in the Body • 04:46 How the Body Makes Nitric Oxide • 07:12 Diet’s Impact on NO Levels • 13:28 Why Most NO Supplements Fail • 19:32 Personalized Biohacking with NO • 22:33 How Medicine Misses the Mark • 30:40 Oral Health and Nitric Oxide • 31:30 Mouthwash Kills Your Microbiome • 32:28 The Problem with Fluoride • 33:25 Better Toothpaste for NO • 33:49 NO’s Role in Energy and Healing • 34:17 Blood Pressure and NO • 35:29 NO and Sexual Performance • 37:09 NO and COVID Recovery • 40:50 Brain Fog and NO Deficiency • 49:01 Carnivore, Sugar, and NO • 50:11 Why You Still Need NO Supplements • 54:19 Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Supercharge your mitochondria, slash inflammation, and boost energy with one of the most overlooked hacks in human performance. This episode reveals how just 15 minutes of oxygen-based exercise can radically improve metabolism, brain optimization, and even reverse chronic conditions, without expensive gear or endless protocols. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Brad Pitzele, founder of One Thousand Roads and creator of the LEO System, an affordable and science-backed way to do Exercise With Oxygen Therapy (EWOT) at home. After nearly dying from autoimmune illness and failed functional medicine treatments, Brad used this oxygen-based biohacking tool to fully reboot his health. His story and system offer breakthrough potential for anyone facing fatigue, inflammation, or looking to upgrade energy, resilience, and longevity.  You’ll learn: • How EWOT works differently from hyperbaric oxygen and why it’s faster • Why brain fog, poor sleep, and chronic inflammation all trace back to oxygen supply • How oxygen hacking activates neuroplasticity, detox pathways, and energy production • When to stack with ketosis, red light, nootropics, and mitochondrial supplements • How elite athletes and chronically ill patients both use this protocol • Why “Smarter Not Harder” starts with oxygen-fueled mitochondrial upgrades This is essential listening for anyone serious about biohacking, functional medicine, brain optimization, metabolism, fasting, supplements, and longevity. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Get a free Ebook on EWOT to learn more today:https://cdn.shopify.com/s/files/1/0097/3186/6683/files/The_Oxygen_Advantage_Protocol_-_EWOT.pdf?v=1752173567 SPONSORS: Puori | Head to http://puori.com/dave for 20% off, including subscriptions.  BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off.  Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • One Thousand Roads Website: https://www.onethousandroads.com/• One Thousand Roads YouTube (more info on EWOT) : https://www.youtube.com/@OneThousandRoadsHQ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Labs: https://upgradelabs.com • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com  Timestamps: • 00:00 Trailer • 01:10 Introduction • 02:38 Discovering EWOT • 03:55 Autoimmune Breakdown • 06:54 Building One Thousand Roads • 15:00 EWOT Science & Benefits • 20:54 Protocols & Use Cases • 29:03 Real-World Results • 30:11 Brain Fog & Oxygen • 30:58 Athletic Performance • 31:41 Therapy Stacking • 34:44 Mitochondria & Aging • 37:08 Research & Studies • 40:00 Future of Oxygen Therapy • 43:02 Practical Tips & Access • 51:09 Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Wrinkles are just the surface. This episode reveals what’s really happening beneath your skin and how to reverse it using stem cells, regenerative medicine, and the most advanced techniques in plastic surgery and aging. You’ll learn how to improve facial skin tightening, reduce inflammation, and trigger deep skin rejuvenation with stem cells, red light therapy, and targeted procedures that actually work. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey shares his personal journey through weight loss and skin excess, including why he had 28 inches of skin removed and how he rebuilt facial structure using stem cells and longevity protocols. He’s joined by Dr. Victor Urzola, a globally recognized expert in plastic surgery and aging, known for pioneering biohacking skin health techniques, cutting-edge facial reconstruction, and legalizing therapeutic stem cell use in Costa Rica.  Together, they expose the hidden causes of wrinkles and aging, from mitochondrial slowdown to ligament laxity and collagen depletion. They also unpack the science behind breast implant health risks, silicone toxicity syndrome, and why thousands of women experience hormonal, neurological, and metabolic symptoms related to their implants. Dr. Urzola explains how explant surgery can improve hormone balance, sleep, HRV, metabolism, and even libido. You’ll also hear how cosmetic procedures interact with HPA axis function and how skin and brain health are more connected than you think. This episode is a must for anyone serious about biohacking, skin optimization, stem cells and longevity, and functional medicine. Dave also breaks down his recovery stack, including exosomes, red light therapy, collagen cycling, nootropics, and how cosmetic procedures can be used to enhance—not just appearance—but total human performance. You’ll learn: • The real root causes of wrinkles and sagging skin • How to use skin rejuvenation with stem cells for long-term results • Signs of silicone toxicity syndrome and what to do about it • Why cosmetic procedures impact hormone health and libido • The most effective strategies for facial skin tightening and recovery• How to approach breast implant health risks with functional medicine thinking Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. SPONSORS: Generation Lab | Go to https://www.generationlab.com/ use code Dave20 for $20 off. Qualia | Go to https://www.qualialife.com/dave15 to get an additional 15% off subscriptions.  fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order.  Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Dr. Urzola’s Website: https://drvictorurzola.com/en/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Labs: https://upgradelabs.com • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:39 Intro • 02:52 Breast Implants & Aesthetics • 03:40 Stem Cells in Cosmetic Procedures • 10:38 Skin Health & Anti-Aging Tips • 15:11 Red Light & Face Stimulation • 17:15 Platysma Muscle & Neck Aging • 21:01 Implant Risks & Reactions • 27:36 Vince & Longevity Science • 28:51 Implant Tolerance Explained • 29:52 Silicone Health Impact • 31:06 Inflammation & Genetics • 32:15 Explant Outcomes & Recovery • 40:14 Breastfeeding & Aesthetic Changes • 41:03 Lift vs. Implants • 45:39 Patient-First Medical Care • 53:32 Stem Cells & Medical Freedom • 56:21 Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Superintelligence is coming faster than anyone predicted. In this episode, you’ll learn how to upgrade your biology, brain, and consciousness before AI and transhumanism reshape the future of health. Host Dave Asprey sits down with Soren Gordhamer, founder of Wisdom 2.0, to explore what superintelligence in 2027 means for your mind, body, and soul. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Soren has spent decades at the intersection of mindfulness, technology, and human development. He advises leaders at OpenAI, Google, and top wellness companies, and he leads global conversations around AI and consciousness. His work bridges ancient wisdom with biohacking, modern neuroscience, and the urgent need to stay human in a machine-dominated world. This episode gives you a tactical roadmap to build resilience before the world tilts. You’ll gain practical tools for brain optimization, functional medicine, and biohacking strategies that sharpen cognitive health, reinforce emotional stability, and unlock peak human performance in a digital-first reality. From supplements and nootropics to neuroplasticity techniques, Dave and Soren show you how to protect your biology as AI accelerates beyond human speed. They break down how AI and human health intersect, explain why you need emotional strength to face the future, and offer guidance for raising kids in a world ruled by code. If you’re preparing for 2027 superintelligence, navigating AI-driven parenting, or staying ahead of transhumanist health tech, this episode equips you for the coming wave.  You’ll Learn: • How AI is reshaping human connection, presence, and identity • Why emotional resilience and conscious awareness matter more than ever in an AI-driven world • How to raise connected, grounded children in a hyper-digital environment • What human flourishing looks like when technology outpaces biology • Why investing in presence, purpose, and inner development may be the ultimate upgrade • How leaders in wellness and tech are rethinking personal growth, governance, and ethics in 2027 • What it means to stay truly human—and fully alive—during the rise of superintelligence  Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes drop every Tuesday and Thursday, where Dave asks the questions no one else dares and gives you real tools to become more resilient, aware, and high performing. SPONSORS: - LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/DAVE.  - ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Soren's New Book - The Essential: https://a.co/d/dALv7OS • Soren's Website: www.sorengordhamer.net • Soren's Instagram: https://www.instagram.com/wisdom2events/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Labs: https://upgradelabs.com • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Creatine isn’t just for bodybuilders. It’s one of the most overlooked, science-backed nootropics for brain optimization, neuroplasticity, mitochondrial energy, and total human performance. This episode reveals why creatine is a non-negotiable supplement for anyone serious about biohacking, longevity, and cognitive upgrades. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey breaks down the myths and truths about creatine, uncovering how it enhances memory, supports your mitochondria, regulates mood, strengthens bones and heart function, and even aids fetal brain development during pregnancy. Drawing from decades of functional medicine, real-world biohacks, and new research featured in the Wall Street Journal, Dave explains how creatine works not only as a muscle booster but as a universal cellular fuel that supports brain benefits, memory improvement, and sleep optimization. You’ll learn how to harness creatine for everything from mental performance and mood regulation to faster recovery and better metabolism. Dave covers creatine dosage and timing, how to use creatine loading versus maintenance protocols, and how to enhance creatine absorption by mixing it with hot water or pairing it with glucose and protein to leverage insulin-sensitive pathways. He also shares next-level stacking strategies by combining creatine with caffeine (including Danger Coffee), beta-alanine, nitrates, and electrolytes to maximize both mental and physical results. Whether you’re using creatine for brain energy, sprint power, cold therapy performance, or cognitive resilience, this episode delivers practical tools you won’t hear anywhere else. If you’re following a carnivore diet, in ketosis, experimenting with fasting, or just want to feel sharper and more energized, creatine fits right in. Dave also explores cutting-edge options like GAA creatine, creatine HCL, and intranasal delivery systems, along with key nutrient pairings like TMG and folinic acid to support methylation and avoid side effects. Plus, he explains why vegetarians and vegans may need creatine the most. This is your complete guide to creatine brain benefits, mitochondrial support, memory enhancement, and smarter not harder living. You’ll Learn: • How creatine supports neuroplasticity, brain energy, and cognitive function • Why mitochondrial health is the key to memory, mood, and mental performance • The real science behind creatine dosage, absorption, and stacking strategies • How creatine fits into ketosis, fasting, and a carnivore lifestyle • Why vegans and vegetarians may suffer from creatine deficiency • How to combine creatine with caffeine, nitrates, and nootropics for peak performance • Ways to biohack your metabolism, muscle growth, and mental clarity • The link between creatine, sleep optimization, and reduced brain fog • How creatine protects against oxidative stress and supports longevity • What you need to know about GAA creatine, methylation support, and delivery mechanisms Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares and brings you real tools to become more resilient, aware, and high performing. SPONSORS: - Calroy | Head to https://calroy.com/dave for an exclusive discount.  - BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino.  Resources:  • Danger Coffee: https://dangercoffee.com • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com  Timestamps: • 00:00 Trailer • 01:14 Creatine for Overall Health and Longevity • 06:10 Addressing Common Myths About Creatine • 08:55 How to Use Creatine Effectively • 19:58 Special Use Cases and Recommendations • 24:58 Choosing the Right Creatine • 28:41 Conclusion and Recap See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if death isn’t inevitable but a solvable problem? This episode explores how biohacking is reshaping our understanding of mortality, legacy, and the limits of human performance. You’ll learn why some of today’s top thinkers are treating longevity as both a science and a spiritual movement, and how this shift affects your brain, your mitochondria, and your entire approach to life. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with philosopher and best-selling author Dr. Stephen Cave, Director of the Institute for Technology and Humanity at the University of Cambridge. With decades of expertise studying death, immortality, and ethics, Dr. Cave brings a rare depth of insight into how our desire to live longer intersects with neuroplasticity, supplements, and even nootropics. Together, they unpack the four universal immortality narratives, the dangers of mind uploading, and why AI might become humanity’s next god or destroyer. You’ll discover how legacy, ego, functional medicine, and even fasting and ketosis play into our fear of death. The conversation also dives into the deeper psychological and societal consequences of radical life extension, and what happens when biohacking crosses into belief. This episode is a must-listen for anyone serious about hacking longevity, brain optimization, metabolism, and building a future where living to 180 isn’t science fiction. You’ll also hear surprising thoughts on Danger Coffee, RFK, sleep optimization, and how to approach mortality using the Smarter Not Harder mindset. You’ll Learn: • Why all technology is a form of life extension • How ego and boredom threaten longevity more than disease • The real dangers of digital immortality and uploading consciousness • Why procrastination could be the enemy of eternal life • How to balance transhumanist tech with human values • The surprising connection between cold therapy, supplements, and meaning Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares and brings you real tools to become more resilient, aware, and high performing. SPONSORS: Puori | Head to http://puori.com/dave for 20% off, including subscriptions. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.  Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order.  Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Stephen's Website: https://www.ith.cam.ac.uk/staff/stephen-cave • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:09 Intro • 01:39 Life Extension Challenges • 02:05 Boredom and Mental Health • 04:28 Immortality vs. Enlightenment • 06:21 Death’s Role in Civilization • 09:06 Life Stages and Aging • 10:41 Global Immortality Narratives • 15:50 Personal Takes on Immortality • 20:46 Biohacking and Longevity • 28:43 Transhumanism Today • 31:00 Techno-Utopianism and Happiness • 32:20 Wealth and Fulfillment • 32:54 Purpose and Meaning • 34:00 Legacy and Death • 36:33 Near-Death and Mortality • 37:52 Time and Procrastination • 42:00 AI and Human Future • 45:56 Ethics of Life Extension • 50:35 Autonomy and Mortality • 52:35 Dangerous Ideas in Longevity • 55:53 Advice for the Young See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

You feel stiff, tired, or older than you should—and this episode shows you how to reverse it. Learn how to fix joint pain, restore youthful movement, and upgrade your longevity by hacking the hidden causes of early aging like mitochondrial dysfunction, leaky gut, and chronic inflammation. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Gregory Kelly, SVP of Product Development at Qualia Life and a leading authority on functional medicine, nootropics, and anti-aging science. Dr. Kelly is a naturopathic physician, author of Shape Shift, former editor of Alternative Medicine Review, and a university instructor who’s published over 30 peer-reviewed papers and contributed to the Textbook of Natural Medicine. His deep expertise spans cellular regeneration, sleep optimization, metabolism, and the chronobiology of performance. They reveal why most joint pain has nothing to do with age, why your cartilage and synovial fluid become insulin resistant, and how biohacking your gut can dramatically improve joint function and brain optimization. You’ll discover how neuroplasticity, metabolism, sleep, and mobility are all tied to your ability to stay pain-free and high performing. Dr. Kelly also breaks down the science behind unconventional joint-support compounds like tamarind seed extract, eggshell membrane, L-carnitine, and senolytics. You’ll Learn: • Why joint pain is often a metabolic and mitochondrial issue, not aging • How zombie cells and gut toxins silently destroy your cartilage • What to take instead of glucosamine to actually rebuild your joints • Why most joint supplements fail and what new research says to use instead • How to enhance mobility using functional medicine and cutting-edge ingredients • How movement, inflammation, and brain health are deeply connected • Tools for real recovery without burnout using the smarter not harder method This channel explores how ketosis, fasting, cold therapy, and smarter not harder strategies affect movement, inflammation, and longevity. Dave also shares how Danger Coffee and his own supplement routines helped him reverse years of joint damage—and how you can do the same without drugs or surgery. This is essential listening for anyone serious about biohacking, human performance, and outsmarting the aging process at any age. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares and brings you real tools to become more resilient, aware, and high performing. Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Qualia’s Website: www.qualialife.com/asprey15• Qualia's Instagram: https://www.instagram.com/qualialife/?hl=en • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:07 Joint Pain vs. Aging • 04:46 Gut-Joint Connection • 06:33 Diet’s Impact on Joints • 10:14 Smarter Joint Supplements • 19:15 Senescent Cells and Pain • 22:47 Collagen Breakdown • 24:21 Tamarind and Turmeric Benefits • 26:34 Inflammation Fixes • 29:39 Mobility and Movement • 38:26 Sleep and Joint Recovery • 42:52 Can You Reverse Joint Damage? • 44:48 Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

93% of people are metabolically unhealthy, and it’s not because they’re lazy or eating too much fat. It’s because their bodies forgot how to burn fat at all. This episode gives you a complete roadmap to reboot your metabolism, escape the sugar-burning trap, and reignite your fat-burning engine for good. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Ben Azadi, functional health expert, best-selling author of Metabolic Freedom, and one of today’s most trusted voices in the ketogenic and fasting space. After reversing his own obesity through biohacking and functional medicine, Ben has helped millions unlock metabolic flexibility and master human performance through smarter-not-harder strategies. They explore how high insulin, not fat or salt, drives most chronic disease, and why your doctor probably isn’t testing for it. You’ll learn the truth about seed oils, fructose, and blood sugar spikes, and why most people using continuous glucose monitors are still missing the real metabolic threat. You’ll also discover how to: • Switch out of sugar-burning mode and back into fat-burning ketosis • Use fasting, cold therapy, and sleep optimization to repair mitochondrial damage • Fix hidden nutrient deficiencies with the right supplements, potassium, and electrolytes • Build real metabolic resilience with Danger Coffee, functional medicine, and nootropics • Avoid the trap of endless keto or carnivore and learn how to cycle your way to true metabolic freedom • Understand why low HRV, high insulin, and sleep debt crush longevity, energy, and brain optimization • Decode how neuroplasticity, emotional regulation, and resilience all connect to metabolism This is your science-backed guide to transforming your energy, losing stubborn fat, and becoming metabolically unstoppable. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. SPONSORS: - BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino.  - IGNITON | Go to https://www.igniton.com/DAVE and use code DAVE to save 15%.  Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Ben’s New Book - Metabolic Freedom: A 30-Day Guide to Restore Your Metabolism, Heal Hormones & Burn Fat: https://www.amazon.com/Metabolic-Freedom-Restore-Metabolism-Hormones/dp/1401994369 • Ben’s Instagram: https://www.instagram.com/thebenazadi/?hl=en • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:04 Intro • 02:42 Insulin Explained • 06:00 Salt vs. Potassium • 08:10 Uric Acid & Fructose • 12:56 Health Trolls • 18:14 Seed Oil Truth • 24:24 Cooking Oil Breakdown • 31:08 Carnivore & Flexibility • 34:57 Gut Test Insights • 36:09 Cholesterol Panel • 36:43 LMHR Explained • 37:39 Inflammation Markers • 40:25 Managing Autoimmunity • 42:07 Gut Bacteria & Fiber • 46:55 Fasting for Gut Health • 48:03 Saturated Fat & Gut • 49:34 Oxalates & Diet • 57:32 Metabolic Efficiency • 01:03:08 Hormesis & Stress • 01:08:21 Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

You’re working out, eating clean, and still not getting the results you want. This episode reveals the real reason your fitness isn’t translating to the summer body you’re chasing and what to do instead. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with performance-driven entrepreneur and former Army Ranger Nick Bare, founder of Bare Performance Nutrition and the Go One More movement. With over a decade of experience in human performance, endurance, and mindset training, Nick has built a cult-like following by pushing the limits of physical and mental resilience without burning out. In this episode, you’ll learn why consistency beats intensity, how to spot the traps of overtraining, and how to train smarter by understanding mitochondria function, recovery science, and sleep optimization. Dave and Nick go deep on longevity tactics, cold therapy, neurohacking rituals, and why emotional regulation is the missing link in high performance. They also break down elite strategies for entrepreneurial stress, parenting under pressure, and how to balance ambition with recovery using tools from biohacking, self-quantification, and functional medicine. You’ll get practical insights into how Upgrade Labs, Danger Coffee, and the principles behind Smarter Not Harder can dramatically boost your energy and focus. Whether you’re an endurance athlete, a sleep-deprived parent, or a business builder trying to avoid burnout, this conversation gives you the blueprint for sustainable energy, powerful willpower, and next-level fitness that actually works. You’ll Learn: • The true cost of overtraining and how to avoid it • How to create “sprints” in life without sacrificing long-term performance • Tactical upgrades for training, sleep, fasting, and emotional recovery • What most people get wrong about motivation and discipline • How to use nootropics, cold therapy, and fasting to accelerate growth • Why fear of mediocrity can be fuel if used correctly • How testosterone, cortisol, and dopamine affect parenting, performance, and purpose Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living.  Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. SPONSORS: - Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order  -Active Skin Repair | Visit http://activeskinrepair.com/ to learn more and use code DAVE to get 20% off your order.  Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Nick’s Website – https://www.nickbare.com/ • Nick’s Instagram: https://www.instagram.com/nickbarefitness/?hl=en • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 00:55 Intro • 02:59 Longevity & health • 07:51 Endurance vs recovery • 20:23 Focus & boundaries • 23:16 Pain & recovery • 24:48 Dopamine & motivation • 25:48 Breath work & states • 28:24 Endurance as meditation • 30:44 Curiosity & fear • 32:22 Purposeful suffering • 33:33 Vision quests • 40:18 Nervous system switching • 45:59 Decision-making • 47:59 Final thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Your everyday habits might be accelerating aging, and this episode reveals what to do instead. You’ll learn how specific plants trigger powerful longevity pathways and how to eliminate the hidden toxins disrupting your hormones, brain, mitochondria, and overall health. This is a masterclass in biohacking from two experts who’ve spent decades researching how to upgrade the human body. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR  Host Dave Asprey is joined by Darin Olien, environmental health expert, bestselling author of Fatal Conveniences, and co-host of the Netflix series Down to Earth with Zac Efron. Darin has traveled the globe uncovering forgotten plant compounds, investigated the most overlooked environmental toxins, and now works with leading scientists and governments to bring these breakthroughs into functional medicine and human performance. Together, they break down: • How rare plant compounds like osmotin support adiponectin and mitochondrial repair • Why PFAS, synthetic fragrances, and EMFs are sabotaging your biology • How environmental toxins contribute to hormone disruption and infertility • What makes tap water so dangerous and how to fix it with simple filtration • Why microplastics and heavy metals are harder to avoid than ever • The role of habit design, detox protocols, and indoor air quality in biohacking longevity • Why removing toxins first leads to better results in fasting, ketosis, nootropics, and cold therapy This episode delivers practical tools for building resilience, improving detox capacity, and navigating the modern world with awareness. You’ll also get insights into the systems that have failed to protect public health and how personal action can create collective change. If you’re interested in senolytics, sleep optimization, neurohacking, and smarter ways to upgrade your environment, you’ll find those topics explored in depth throughout this channel. Whether you’re detoxing from hidden toxins or optimizing with Danger Coffee, this conversation aligns with the core principles of Smarter Not Harder and the mission of Upgrade Labs. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. SPONSORS: -OneSkin | Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY. -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order.  -Apollo Neuro | To get an Apollo wearable, go to https://apolloneuro.com/Dave and save 15%. Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Darin’s Website – https://superlife.com/ • Darin’s Instagram: https://www.instagram.com/darinolien/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com  Timestamps: • 00:00 Trailer • 01:10 Intro • 02:14 Meet Darin Olien • 04:26 Wildfires and Pollution • 07:13 PFAS and Everyday Toxins • 12:37 Corporate and Regulatory Failure • 26:36 Synthetic Fragrances • 36:12 Water and Air Filtration • 36:53 Indoor Air Quality • 38:33 Building Healthy Habits • 40:05 Essential Oils and Hormones • 41:54 Tofu, Tempeh, and Estrogen • 46:34 Adiponectin and Biohacking • 47:04 Osmotin for Longevity • 49:48 Stem Cells and Repair • 53:57 Communicating Science • 01:04:12 Nutrition and the Microbiome • 01:06:14 Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Your anti-aging skincare routine might be secretly aging you faster. In this episode, you’ll uncover how trending skincare products including vitamin C serums, harsh exfoliants, and blue light therapies can damage your skin’s mitochondria, accelerate senescence, and trigger systemic inflammation. You’ll learn how to reverse this damage, support cellular repair, and choose smarter formulations that work with your biology for long-term skin and brain health. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Amitay Eshel, a pioneer in biohacking skincare and founder of Young Goose. With expertise in regenerative aesthetics and advanced bioactive formulations, Amitay is leading the charge in applying longevity science, epigenetics, and senolytics to skincare. His work helps high performers integrate topical nootropics, mitochondrial support, and neurohacking principles directly into their daily routine through the skin. You’ll explore how skin aging connects to brain inflammation, how leaky skin barriers affect immune health, and why most anti-aging trends are outdated or biologically disruptive.  The Human Upgrade unpacks how red-light therapy, ketosis, cold therapy, fasting, and self-quantification tools can be leveraged to enhance skin function from the inside out. This is a masterclass in smarter not harder skincare, rooted in cellular optimization and performance longevity. This episode is essential listening for anyone serious about biohacking, human performance, skincare longevity, mitochondria, Upgrade Labs-style recovery, and science-backed beauty routines. You’ll learn: • Which anti-aging skincare trends actually age you faster • How mitochondria and senescent cells influence visible aging and inflammation • What role neurohacking and the skin-brain connection play in longevity • How to repair the skin barrier and reduce oxidative stress naturally • The best red light, cold therapy, and fasting tools to reverse skin aging • How to use skin as a self-quantification tool for overall health • Why smarter skincare equals better cognitive and biological performance Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. SPONSORS: -OneSkin | Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY.  -fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE.  -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Young Goose Website – https://www.younggoose.com/ and use code “Dave10” at checkout to get a discount! • Young Goose Instagram: https://www.instagram.com/young_goose_skincare/?hl=en • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 00:52 – Intro • 01:27 – Anti-Aging Mistakes • 05:20 – Skin Recovery Science • 07:44 – NAD & Mitochondria • 08:52 – Autophagy Compounds • 12:06 – Sleep & Topicals • 18:36 – Overtraining Effects • 21:07 – Vitamin C & Antioxidants • 28:48 – Breakthrough Formulations • 35:50 – Tallow vs. MCT • 36:11 – Sun & Longevity • 37:28 – Red Light Therapy • 40:12 – UV Light Benefits • 42:18 – Advanced Skincare Tech • 48:48 – NAD Topicals • 01:00:05 – Building Your Routine • 01:07:39 – Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most supplements don’t work, and this episode reveals why. You’ll learn how to stop wasting money on “expensive pee,” how to spot marketing lies on labels, and which ingredients actually move the needle for energy, focus, and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Jeff Boyd, founder of MTE and a leader in the new wave of performance supplements. With a background in data-driven wellness and a decade of experience optimizing human performance without caffeine or sugar, Jeff breaks down the science of nootropics, adaptogens, and smart nutrient stacking. His work focuses on self-quantification, nervous system regulation, and sustainable energy for founders, athletes, and high performers. Together, they explore why 85% of supplements are designed to fail, how to activate mitochondria for real results, and what it means to biohack your biology smarter, not harder. This isn’t just about supplements. It’s about reclaiming your energy, upgrading your brain, and aligning your stack with how your body actually works. You’ll also hear how fasting, sleep optimization, and even subtle neurohacking protocols support long-term resilience and better decision-making. You’ll Learn: • The real reason most supplements don’t absorb and how to fix it • How to build a caffeine-free stack that fuels energy, mood, and clarity • The latest in adaptogens, nootropics, and functional medicine • How to align your supplement timing with circadian biology and ketosis • Why “clean labels” often mean nothing • How emotional regulation and neurotransmitters shape performance • Tools for self-quantification and supplement personalization This is essential listening for anyone serious about biohacking, longevity, smarter supplementation, mitochondrial health, sleep optimization, emotional resilience, and conscious human performance. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks questions no one else dares and brings you real tools to become more resilient, aware, and high performing. Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • MTE website – www.getmte.com • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:13 Saffron Benefits • 02:26 Medicinal Herbs • 04:12 Supplement Formulation • 13:16 Theanine & GABA • 20:06 Adaptogens & Performance • 23:23 Stress & Muscle Growth • 24:03 Parenting & Energy • 27:47 Nervous System for Kids • 35:15 Sleep for Families • 36:41 Wrap-Up & Offers See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Psychedelic therapy is on the verge of reshaping mental health, trauma healing, and human consciousness. This episode reveals what’s really happening behind the scenes at the FDA, inside pharmaceutical companies, and within the global movement to legalize MDMA-assisted therapy. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Rick Doblin, PhD, the legendary founder of MAPS and one of the most influential figures in psychedelic science. With nearly 40 years leading clinical research on MDMA, psilocybin, and trauma healing, Rick brings unmatched insight into how these compounds are transforming functional medicine, emotional resilience, and neuroplasticity. They break down the regulatory battle over MDMA therapy, the clash between pharmaceutical profit and public benefit, and the urgent need to combine pharmacology with therapy for real results. You’ll also learn how psychedelics impact neurohacking, epigenetics, and the default mode network—and why the next frontier of self-transformation may be couples therapy with MDMA. This episode offers critical knowledge for anyone serious about biohacking, trauma release, mental performance, and accessing deeper states of healing. This podcast channel dives into the intersections of psychedelics with fasting, ketosis, cold therapy, and self-quantification—and how altered states can unlock more energy, better relationships, and lasting change. You’ll Learn: • Why separating therapy from psychedelics is the most dangerous path forward • How MAPS evolved into a public benefit pharma company—and what went wrong • The real story behind the FDA’s rejection of MDMA therapy in 2024 • How MDMA affects neuroplasticity, mitochondria, and trauma recovery • Why group therapy and couples therapy are the future of psychedelic healing • The dangers of overusing ketamine—and how it’s being exploited by profit-driven clinics • What the Psychedelic Science 2025 conference will reveal about the future of medicine, spirituality, and consciousness hacking • How psychedelics could reverse epigenetic trauma passed down through generations • The role of default mode network suppression in spiritual experiences and trauma resolution • Why the war on drugs was never about safety—and what a post-drug-war world might look like Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, neurohacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. SPONSORS: - Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off- ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order  Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Psychedelic Science Conference 2025 Website – https://www.psychedelicscience.org/ • Rick’s Website: https://maps.org/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 02:00 Intro • 03:43 Rise of Psychedelic Pharma • 05:00 Therapy vs. Profit • 06:44 Neurofeedback + Psychedelics • 08:28 Origins of Drug Laws • 14:06 MDMA Safety + Usage • 16:32 Psychedelics in Therapy + Meditation • 25:18 Psychedelic Hierarchy for New Users • 26:51 Psychedelic Churches + Culture • 28:58 Ayahuasca: Spiritual Insights • 30:24 MDMA and Federal Policy • 31:09 Inside the FDA Decision • 32:52 Therapeutic Promise of Psychedelics • 34:43 Psychedelics + Spirituality • 37:37 Neuroscience of Psychedelics • 40:12 Epigenetics + Generational Trauma • 43:50 War on Drugs Revisited • 46:37 Future of Legalization • 49:55 MDMA for Couples • 51:29 Group Therapy with Psychedelics • 52:26 Psychedelic Science 2025 Preview See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

You’ve been told to eat clean, but what if your “healthy” foods are wrecking your gut, crushing your hormones, and aging you faster? This episode exposes the nutrient-depleted truth behind modern diets, soil erosion, and why regenerative farming might be the key to reversing chronic disease, boosting mitochondria, and rebuilding your biology from the ground up. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Josh Axe, a trusted pioneer in functional medicine, bestselling author, and co-founder of Ancient Nutrition. Dr. Axe bridges the gap between biblical farming, ancestral nutrition, and modern science to explain how your food and even your supplements may be harming your human performance, digestion, and brain health. With clinical insights, personal stories, and science-backed tools, he shares what to eat instead if you want real longevity, energy, and healing. They dig into the collapse of soil nutrients, how monocropping damages the microbiome, and why organic food standards may be outdated. You’ll learn how regenerative agriculture rebuilds the earth and your gut, and why biohacking starts with dirt, not pills. Plus, they explore the hormonal chaos caused by seed oils, plastics, blue light, sleep disruption, and even birth control, especially in relation to testosterone loss in men and women. This episode also touches on biblical nutrition, fasting cycles, natural nootropics, testosterone-supporting peptides, the dangers of synthetic vitamins, and the future of real-time self-quantification. From poop-powered farming to smarter sourcing, it’s a wild ride into how food, faith, and farming affect every part of your biology. This is essential listening for anyone serious about biohacking, neurohacking, longevity, Upgrade Labs, Danger Coffee, Smarter Not Harder, and understanding the real root of disease and dysfunction. You’ll Learn: • Why regenerative farming beats “organic” for health and the planet • How depleted soil is linked to hormone imbalances and chronic disease • What birth control is doing to testosterone, fertility, and mitochondrial health • Why your supplements may just be “expensive pee” • The truth about biblical farming and why dirt still matters • How to support testosterone naturally with diet, peptides, and habits • Why sleep optimization, mineral balance, and circadian alignment are key for healing Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing.  SPONSORS: - BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off.  - Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Josh Axe’s Website – https://thehealthinstitute.com/ • Josh Axe’s Instagram: https://www.instagram.com/drjoshaxe/?hl=en • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 00:52 Intro • 01:01 From Medicine to Farming • 02:21 Regenerative Farming • 03:36 Fixing Modern Agriculture • 05:43 Biblical Farming Meets Modern Science • 08:23 The Truth About Organic Food • 12:41 What’s Causing the Testosterone Crash • 18:07 Hormonal Birth Control • 27:37 New Hormone Replacement • 29:58 The Future of Health Tracking • 32:00 What Is Biblical Farming? • 33:38 Biblical Principles of Nutrition • 33:55 Foods Most Mentioned in the Bible • 35:17 Pork, Parasites, and Dietary Laws • 37:29 Chinese Medicine’s View on Pork • 39:36 Did the Flood Shorten Human Lifespan? • 42:26 Biodynamic Farming and Spirituality • 54:27 Fatherhood and Words That Heal • 56:21 What Josh Feeds His Kids • 01:03:41 Mental Health, Faith, and Healing • 01:05:36 Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Your brain is under constant assault from devices you use every day. This episode reveals the hidden effects of 5G on brain function, cognitive performance, and nervous system stress, along with the science-backed method that neutralizes the damage. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Philipp Samor von Holtzendorff-Fehling, founder of Quantum Upgrade and a former VP at T-Mobile, to explore groundbreaking EEG research that shows how EMF exposure disrupts brainwaves in real time. Philipp shares how new tools are changing the way we approach biohacking, human performance, and energy medicine, and why even hardcore skeptics are paying attention.  They break down double-blind studies, ATP production, and real-world EMF mitigation techniques that support brain health, mitochondrial resilience, and recovery. You’ll hear why professional athletes, clinicians, and even animals are benefiting from non-invasive approaches once dismissed as fringe, and how to evaluate what actually works in your own biology. This conversation is essential for anyone focused on biohacking, self-quantification, neurohacking, longevity, functional medicine, Upgrade Labs protocols, and protecting the brain in a wireless world. Whether you’re optimizing your nervous system, improving sleep, or just trying to stay sharp in a high-EMF environment, this episode gives you a toolset to reclaim your state. You’ll learn: • What EEG brain scans reveal after just 30 minutes of 5G exposure • Why ATP production increases in certain energetic fields • How energy fields influence brainwaves, stress, and performance • The connection between EMFs, mitochondrial function, and resilience • Why placebo doesn’t explain these results and what that means for self-tracking • How to use energetic tools alongside Danger Coffee, cold therapy, fasting, and nootropics Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living.  Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares and brings you real tools to become more resilient, aware, and high performing. SPONSORS: - Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.  - Calroy | Head to https://calroy.com/dave for an exclusive discount.  Resources:  • Quantum Upgrade Website – Go to https://quantumupgrade.io/Dave for a free trial. • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Quantum Upgrade Instagram: https://www.instagram.com/quantumupgrade.io/?hl=en • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 00:54 Intro • 01:18 Resistance to Energy Work • 03:25 Inner Intuition • 04:22 Science vs Experience • 09:12 Quantum Effects on Body • 13:43 Biohacking for Pets • 15:43 EMFs & Quantum Upgrade • 23:39 Explaining Quantum Tech • 27:58 Understanding Frequencies • 28:53 Scientific Proof & Use • 31:07 Brain Support Tools • 32:28 Ethics & Consent • 34:09 EMF Defense & Biofield • 39:07 Meditation & Altered States • 46:59 Performance Optimization • 48:02 Science Catching Up • 50:39 Free Trial & How to Try See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most people think 10,000 steps a day is the gold standard for health, but it’s outdated, inefficient, and often damaging. In this episode, you’ll discover a smarter, faster way to walk for longevity, fat burning, and total body resilience. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Mark Sisson, bestselling author, primal health pioneer, and founder of Primal Kitchen. With over 40 years at the forefront of fitness and ancestral health, Mark has helped millions rethink everything they thought they knew about cardio, running, metabolism, and movement. He was one of the first to challenge the chronic cardio myth, helped popularize ketosis and fat-adapted performance, and now returns with a new message: walking right, not more, is one of the most powerful biohacks for human performance and aging. They dive into the Japanese walking interval method that outperforms 10,000 steps, and explore the critical link between foot health, barefoot shoes, and the brain-body connection. Mark also shares why he trains just 20 minutes a week, why too much saturated fat might backfire, and why performance should never come at the cost of your mitochondria. You’ll learn how to build muscle and endurance with less effort, how to reverse foot dysfunction with every step, and how to age with strength, intuition, and freedom. This episode hits hard on biohacking, functional movement, longevity, self-quantification, and the real science of walking smarter, not longer. It’s also packed with insights on ketosis, nootropics, sleep optimization, and why perfectionism ruins health gains. If you’re serious about Smarter Not Harder strategies, tuning into your body, and reclaiming your natural performance potential, don’t miss this one. You’ll learn: • Why zone 1 walking beats zone 2 training for longevity • How foot dysfunction leads to systemic breakdown • The hidden brain-glute-big toe connection no one talks about • Why Mark no longer runs or eats ribeyes • The minimum effective dose for strength, mobility, and fat burn • Why perfectionism in wellness is toxic and what to do instead Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. **Go to www.peluva.com and use code ‘DAVE’ for 15% off ** SPONSORS: - LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/DAVE.  -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial.  Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Mark’s Website –  www.peluva.com • Mark's Instagram: https://www.instagram.com/wearpeluva/?hl=en • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 00:43 – Intro • 01:13 – Mark’s entrepreneurial journey • 04:53 – The rise of health blogging • 05:40 – Why cardio might be hurting you • 17:53 – Foot health and performance • 20:54 – Barefoot and minimalist footwear • 33:30 – Launching PVA Shoes • 42:59 – Diet’s role in foot recovery • 43:38 – Why comfort matters in footwear • 44:12 – Personal footwear hacks • 45:03 – Building a footwear brand • 46:21 – Fashion vs function in foot health • 49:17 – Simple foot strengthening tools • 52:35 – What history reveals about shoes • 58:47 – Walking and brain optimization • 01:06:41 – Protein, aging, and nutrition • 01:19:50 – Longevity and biohacking wins See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This episode dives into the brutal, mind-altering experience of spending 60 days alone in Antarctica, and how extreme suffering became a catalyst for spiritual awakening, peak performance, and deep inner peace. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR  Host Dave Asprey sits down with elite adventurer, Marine Corps veteran, and Fearvana founder Akshay Nanavati, who dragged a 420lb sled solo across Antarctica in a brutal test of endurance, fasting, and spiritual transformation. Akshay shares how he used suffering as a tool to transmute PTSD, expand consciousness, and awaken what he calls the “paradox of oneness”—where discomfort unlocks the deepest joy. Together, they explore how cold therapy, isolation, and extreme hardship reshape dopamine, mitochondria, neurochemistry, and the stories we tell ourselves. Akshay’s journey through darkness retreats, trauma healing, and polar expeditions opens a raw and unfiltered look at self-quantification, mental resilience, and human performance at the edge. This episode will challenge your assumptions about comfort, suffering, and what it means to live fully awake. Whether you’re optimizing for longevity, exploring consciousness, or breaking free from invisible scripts, this conversation blends science, spirituality, and hardcore biohacking with moments of unexpected humor and wisdom. You’ll Learn: • How intentional pain resets your dopamine response and boosts performance • Why Akshay chose fasting and cold exposure over nootropics and psychedelics • How darkness retreats and solitude sharpen consciousness and intuition • The neuroscience behind pain, trauma, and transformation • Why true freedom lies in facing discomfort—not avoiding it • How to find God in suffering and create meaning from chaos Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. SPONSORS: - Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. - IGNITON | Go to https://www.igniton.com/DAVE and use code DAVE to save 15%. Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Akshay’s Website – https://fearvana.com/ • Akshay’s Instagram: https://www.instagram.com/fearvana/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 00:58 – Intro • 01:55 – Meeting His Wife Through Intuition • 06:28 – Pain, Dopamine & Neurohacking • 15:19 – The Paradox of Oneness • 21:20 – Darkness Retreats & Mysticism • 34:39 – Constructing Reality • 38:32 – Consciousness & Perception • 39:18 – Polar Travel: Mental & Physical Strain • 40:22 – Calculated Risk vs. Suffering • 43:40 – Trauma as Fuel • 56:26 – Solitude & Self-Reflection • 01:05:45 – Embracing Fear & Building Courage • 01:09:29 – Death, Meaning & Bliss • 01:12:53 – Final Reflections on Purpose See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This episode reveals how one simple breath pattern can rewire your nervous system, regulate stress in seconds, and become your most powerful tool for human performance and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Aaron Alexander, a world-renowned human performance coach, manual therapist, and creator of The Align Method. Aaron has worked with elite athletes, high-level entrepreneurs, and celebrity performers to transform the way they move, breathe, and live in their bodies. He merges structural alignment, functional medicine, emotional awareness, and deep nervous system science to help people get unstuck, physically and emotionally. Together, they explore the science and strategy behind breathwork, vagal tone, posture, and fascia, revealing how the body stores trauma, how breath shifts brain states, and how physical misalignment can sabotage mental clarity, energy, and even mitochondrial function. They also dive into why mouth taping, tongue posture, nitric oxide, and movement patterns are foundational to sleep optimization, cold therapy adaptation, and long-term vitality. You’ll learn how to regulate your state in 10 seconds or less, how to shift from sympathetic overdrive to parasympathetic calm, and how to use tools like humming, OMing, and deep exhales to control your biology in real time. This is a tactical, science-rich, emotionally grounded guide to neurohacking from the inside out. If you care about biohacking, functional medicine, sleep optimization, or want to feel stronger, calmer, and more in control—this episode is essential. You’ll also hear how Aaron: • Uses breath patterns to hack the nervous system and improve strength, mood, and cognition • Teaches mouth taping and facial alignment for deeper sleep and recovery • Connects trauma, honesty, and physical tension through a somatic lens • Guides clients through cold therapy, touch, and movement to recalibrate resilience • Applies fascia science and polyvagal theory to elite performance and everyday health This is essential listening for anyone exploring Smarter Not Harder protocols, high-level biohacking, and the connection between movement, mitochondria, and mind control. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living.  Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares and brings you real tools to become more resilient, aware, and high performing. SPONSORS: - Sunlighten | Go to https://www.sunlighten.com/dave/ and enter code DAVE at checkout to save up to $1,400. Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Aaron’s Website –  www.alignpodcast.com • Aaron's Instagram: https://www.instagram.com/aaronalexander/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:39 Intro: Walking, lifestyle design, and longevity • 05:38 Breathwork to shift state and boost energy • 21:16 Honesty, alignment, and nervous system health • 29:35 Safety, regulation, and somatic awareness • 30:43 Touch as therapy and connection • 31:53 Pheromones and subconscious signaling • 35:00 Breath as a tool for emotional control • 39:33 Growth through relationships and repair • 43:03 Nature’s role in healing and performance • 47:25 Tongue posture, eye movement, and fascia • 56:32 Final thoughts on presence and physical truth See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This episode reveals the ancient health protocols Western medicine forgot, and how they are now being used to heal stress, rewire the nervous system, and radically improve human performance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Mona Sharma, a renowned Ayurvedic practitioner, celebrity wellness expert, and functional medicine advocate who grew up in a Canadian ashram. Mona combines ancient Vedic practices with cutting-edge science to help her clients, including Will Smith and other high-profile figures, achieve high performance, emotional resilience, and deep-rooted healing. She translates the 5,000-year-old system of Ayurveda into practical strategies anyone can use to optimize health in today’s chaotic world. Together, they explore how Ayurvedic biohacking techniques like breathwork, circadian alignment, detoxification, and herbal medicine are now being validated by data in neuroscience, mitochondrial biology, and functional medicine. They also dive into trauma, stress rewiring, nervous system resilience, and how to build your own modern “ashram” for healing and longevity. You’ll learn how to shift from hypervigilance into calm, how to optimize vagal tone, and how ancient practices like tongue scraping and ghee detox intersect with modern tools like cold therapy, nootropics, sleep optimization, and self-quantification. If you care about biohacking, neurohacking, longevity, or want to understand how emotional states shape mitochondrial function, this episode is packed with grounded insight and powerful takeaways. It offers a masterclass in approaching health through both spiritual and systems biology perspectives, while avoiding burnout and noise. You’ll also hear how Mona: • Reversed her own heart condition after failed surgeries and medication • Guides high-stress clients using Ayurvedic principles and modern lab testing • Connects vagal nerve stimulation, breathwork, and emotional detox for lasting nervous system regulation • Uses personalized nutrition, pulse reading, and lifestyle upgrades to treat the root cause • Brings ancient healing into modern wellness spaces like Upgrade Labs This is essential listening for anyone exploring Smarter Not Harder protocols, blending functional medicine with high-level biohacking, and finding sustainable ways to enhance vitality without relying on pharmaceuticals or performance fads. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares and brings you real tools to become more resilient, aware, and high performing.  SPONSORS: -Calroy | Head to https://calroy.com/dave for an exclusive discount.  -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Mona’s Website –  https://www.monasharma.com/ • Mona’s Instagram: https://www.instagram.com/monasharma/?hl=en • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 00:54 Intro • 01:44 Mona’s Personal Healing Journey • 03:42 What Ayurveda Really Is • 07:15 Breathwork and Daily Rituals • 09:41 Where Western Medicine Falls Short • 13:27 Ancient Tools That Still Work • 22:02 Nervous System as the Healing Key • 31:50 Rewiring Through Visualization • 32:59 Transformations with Celebrity Clients • 33:31 Stress in the Public Eye • 34:18 Finding Core Values and Alignment • 35:48 Home Detox, Real Impact • 37:52 Blending Body and Spirit • 48:52 Understanding Your Dosha • 54:02 Applying Ayurveda Today • 58:34 Final Thoughts and Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

You’re being programmed, and it’s more subtle and pervasive than you think. From invisible influence to psychological manipulation, this episode shows you how to recognize when your thoughts aren’t really yours. Host Dave Asprey uncovers the hidden science of mind control with Harvard historian Rebecca Lemov. She is a professor of the History of Science at Harvard University and one of the world’s leading experts on psychological manipulation, surveillance science, government experimentation, and Cold War brainwashing programs. Her groundbreaking research into MK Ultra, behavioral psychology, and reeducation campaigns reveals exactly how external forces hijack your thoughts, emotions, and decisions, without you knowing. They break down how mind control evolved from CIA-funded brain implants and LSD experiments into today’s algorithmic persuasion, trauma-based manipulation, and tech-driven influence. This episode gives you practical tools to defend your thoughts, upgrade your awareness, and reclaim your mental sovereignty. This is essential listening for anyone serious about biohacking, mindfulness, longevity, mental performance, self-awareness, hacking the nervous system, emotional control, and high-performance mindset training. You’ll Learn: • How the CIA used MK Ultra, psychedelics, hypnosis, and implants to test behavior control • What mind control looks like in modern media, social platforms, and persuasive technology • How unresolved trauma and emotional blind spots leave you vulnerable to manipulation • The connection between neurohacking, mindset, and mental autonomy • How to recognize when you are running someone else’s code • The best psychological tools to build resilience and conscious awareness • How to build a “mental firewall” with meditation, breathwork, and attention training Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. SPONSORS: -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. -OneSkin | Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY. Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Rebecca’s New Book – The Instability of Truth: https://wwnorton.com/books/9781324075264 • Rebecca's Website: https://rebeccalemov.com/• Rebecca’s Instagram: https://www.instagram.com/rebeccalemov/?hl=en • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:01 Intro • 01:49 Mind Control at Harvard • 02:54 Hypnosis and Mental Programming • 04:48 Morning Routines and Meditation • 06:02 AI Companions and Digital Influence • 11:17 MK Ultra and Government Experiments • 20:25 Archives and the War on Truth • 24:49 Marketing and Manipulation • 27:22 Chilling CIA Mind Control Stories • 33:59 Meditation and God Encounters • 34:40 Biohacking Origins • 35:15 Building Mental Resilience • 36:11 Compassion as Control • 37:54 Escaping Modern Programming • 39:57 Free Will vs. Influence • 46:03 Therapy and Suggestion • 49:25 SEER Training and Torture Simulation • 01:03:27 One-Pointed Focus • 01:06:46 Final Reflections See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Your brain runs slow when it’s running on the wrong fuel. In this episode of The Human Upgrade, Dave Asprey sits down with Geoffrey Woo, Stanford-trained computer scientist and founder of Ketone-IQ, to reveal the high-performance brain fuel once reserved for Special Forces and elite athletes. Discover how ketones helped operators in combat zones sharpen focus, recover faster, and boost reaction speed by up to 30%. Learn why glucose falls short, how to hack your mitochondria for better cognition, and what it takes to unlock rapid-fire thinking on demand. This is brain energy for people who want to win, at life, work, and everything in between. Whether you’re fasting, flying, or facing real pressure, ketones flip the switch. You’ll Learn: • Why ketones beat glucose for focus, speed, and mental clarity • How Special Forces use ketones to recover brain function under stress • The truth about esters, salts, and the new wave of ketone diols • How ketones support faster thinking, emotional control, and clean energy • What makes Ketone-IQ different, and how Dave stacks it for peak performance • The best ways to combine ketones with fasting, workouts, and meditation • Why your metabolism controls your mood, reaction time, and resilience Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Ketone-IQ Website –  https://ketone.com/pages/dave-asprey?utm_source=partners&utm_medium=referral&utm_campaign=DAVE • Geoffrey's Website: https://www.geoffreywoo.com/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 02:00 – Intro • 02:12 – Ketosis & brain performance • 02:53 – Geoffrey’s background • 03:52 – Ketone supplement evolution • 04:41 – What makes Ketone-IQ different • 07:18 – Manufacturing breakthroughs • 13:53 – Entrepreneur mindset • 18:58 – Future of biohacking • 45:59 – Why classics still matter • 46:23 – Cultural decline • 47:04 – Decentralization • 48:25 – Info overload & mental clarity • 49:38 – Ketones & consciousness • 57:49 – Religion & belief systems • 01:03:32 – Key biohacking biomarkers • 01:12:47 – Brain data & future upgrades • 01:26:34 – Listener offer See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Your cells are starving. Not for food—but for oxygen. In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Jason Sonners, world-renowned hyperbaric expert and regenerative medicine pioneer, to reveal how controlled oxygen under pressure is becoming one of the most powerful tools in anti-aging and performance science. You’ll learn how hyperbaric oxygen therapy (HBOT) triggers stem cell activation, rewires your epigenome, boosts mitochondrial energy, and reverses biological aging—if you use it the right way. Jason shares breakthrough findings from his latest PhD research comparing low- and high-pressure chambers, with surprising results on inflammation, telomeres, cognitive performance, and recovery speed. This is next-gen longevity—measurable, stackable, and customizable. From sleep upgrades and HRV boosts to stacking HBOT with fasting, methylene blue, or red light, this episode dives into what it takes to oxygenate your biology at the deepest level. You’ll Learn: • How hyperbaric oxygen therapy (HBOT) triggers stem cell regeneration and cellular repair • Why mild-pressure chambers may be more powerful than you think• What HBOT does to inflammation, brain fog, and biological aging markers • How to stack HBOT with fasting, red light, and methylene blue for amplified results • What Dr. Sonners’ PhD research reveals about oxygen pressure and genetic expression • The truth about oxygen toxicity—and how to avoid the common mistakes • How elite performers use HBOT for brain optimization, recovery, and resilience ** Get 30% of yourr tickets to the Biohacking conference by going to https://biohackingconference.com/2025 and use code ‘OXYHEALTH’ ** Thank you to our sponsors!  -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order.  -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Jason's Website –  www.hbotusa.com • OxyHealth Website: https://www.oxyhealth.com/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com  Timestamps: • 00:00 Trailer • 01:59 Intro • 03:14 New research on aging and oxygen • 05:39 Mild vs. hard-shell chambers • 13:05 HBOT for longevity and stem cells • 16:43 How to optimize your sessions • 22:35 Best therapies to stack with HBOT • 25:40 Oxygen delivery and safety • 26:43 Altitude and chamber effects • 30:01 Key benefits of hyperbaric therapy • 34:22 Supplement synergy and timing • 37:25 Pressure and oxygenation findings • 39:27 Medical vs. welding oxygen • 44:57 Safety myths and toxicity risks • 47:39 Future of biohacking with oxygen See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Your brain has a gear you’ve never touched. Psychedelics can shift you into it. In this episode of The Human Upgrade, Dave Asprey uncovers how high-performance psychedelic mushrooms help you access flow states, rewire your brain, and enhance clarity, energy, and emotional resilience. This is next-level biohacking rooted in real science. You will learn how to use psychedelics with intention. When to microdose. When to go deep. How to stack them with nootropics for even stronger results. Dave breaks down the latest research on psilocybin, brain plasticity, trauma release, and how to turn ancient compounds into modern performance tools. What You Will Learn in This Episode: • How psychedelic shrooms unlock flow, focus, and creative power • Why psilocybin boosts neuroplasticity, mood, and emotional healing • Microdosing vs. full-dose: what works, when, and how • How to stack psychedelics with nootropics and other biohacks • The newest research on brain optimization and long-term benefits • How to use psychedelics safely, strategically, and for real results • Why shrooms may be the strongest mental upgrade in your toolkit Thank you to our sponsors!  -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial.  -fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE.  Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Matt’s Website –  https://mattzemon.com/ • Matt's Instagram - https://www.instagram.com/matt.zemon/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 01:00 – Intro • 06:01 – Personal Psychedelic Journeys • 07:39 – Psychedelics and Self-Discovery • 11:59 – Safe Use and Smart Navigation • 29:09 – Psychedelics and Society • 36:40 – Building Trust in the Process • 37:14 – Facing Inner Fear • 37:38 – Choice and Healing • 37:51 – Diet and Conscious Decisions • 38:55 – Judgment and Relationships • 39:29 – Spirituality and Psychedelics • 40:07 – The Entheogenic Reformation • 41:29 – Past Lives and Expanded States • 43:44 – Where Science Meets Spirituality • 49:59 – Gratitude and Compassion in Healing • 01:01:47 – The Power of Apologies • 01:04:56 – Psychedelics in Therapy • 01:08:57 – Final Thoughts on Psychedelics and Culture See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Low testosterone is sabotaging your health, motivation, and longevity. Diet alone will not fix it. In this episode of The Human Upgrade, Dave Asprey sits down with Shalin Shah, CEO of Marius Pharmaceuticals, to expose the truth about testosterone decline in both men and women. They break down why testosterone is crashing worldwide, why natural fixes almost always fail, and how the latest science finally makes testosterone therapy safer, simpler, and more effective than ever before. You will discover why testosterone is essential for dopamine, brain function, sleep, muscle, libido, and mitochondrial health. Fixing your levels can reverse fatigue, brain fog, poor motivation, and slow aging itself. Shalin reveals how new oral testosterone technology (Kyzatrex®) overcomes the dangers of old therapies and restores natural hormone rhythms without needles, creams, or dangerous side effects. What You Will Learn in This Episode: • Why testosterone matters for men and women at every age • The real causes of the global testosterone crash • Why diet, sleep, and exercise cannot fully fix low testosterone • How testosterone drives dopamine, motivation, and longevity • The breakthrough that makes oral testosterone safe and effective • How Kyzatrex® lowers SHBG and boosts free testosterone naturally • Why maintaining youthful testosterone levels protects brain, muscle, libido, and lifespan • How to safely use testosterone therapy without suppressing fertility or causing side effects ** Visit livethrive.co/asprey to get a discount on your first month's supply! ** Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Purchase Kyzatrex® – https://livethrive.co/?utm_campaign=11813552-Asprey• Shalin’s Instagram - https://www.instagram.com/themetabolicceo/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: 00:00 Trailer 00:52 Introduction 01:29 Global Decline in Testosterone Levels 02:27 Symptoms of Low Testosterone 03:48 Personal Journey with Testosterone Therapy 05:06 The Role of Testosterone in Overall Health 06:18 Testosterone Levels in Men and Women 08:48 Challenges and Innovations in Testosterone Delivery 16:25 The Importance of Circadian Rhythm in Testosterone Therapy 19:19 The Future of Testosterone Therapy 32:00 Investment and Development in Testosterone Therapy 34:57 Introduction to FDA and Hormone Replacement 35:31 FDA’s Impact on Women’s Health 36:10 Testosterone and Cardiovascular Risk 39:05 Testosterone and Depression 40:30 Testosterone Testing and Misconceptions 44:58 The Testosterone Project and Female Hormone Therapy 47:51 Testosterone’s Role in Longevity and Health 55:37 Cost and Accessibility of Testosterone Therapy 01:04:03 Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Your environment is rewiring your hormones, fertility, and long-term health without your consent. In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Aly Cohen, board-certified rheumatologist, integrative medicine specialist, and environmental health educator. Together they expose how common toxins in plastics, pesticides, drinking water, personal care products, and food packaging are hijacking your biology. Dr. Cohen explains how daily chemical exposures contribute to autoimmune disease, thyroid dysfunction, hormone imbalance, infertility, obesity, cancer, and accelerated aging. You will learn how to identify hidden endocrine disruptors, spot surprising sources of microplastics and PFAS (“forever chemicals”), and apply science-backed detox strategies to protect your hormones, fertility, metabolism, and longevity. What You’ll Learn in This Episode: • How chemicals in household, cleaning, and beauty products disrupt hormones • The link between environmental toxins, autoimmune disease, thyroid issues, and infertility • Hidden sources of microplastics and PFAS chemicals and how to eliminate them • Affordable, practical steps to detox your home, water, and personal care routine • Dr. Cohen’s top biohacks to protect fertility, balance hormones, and build toxin resilience  THANK YOU TO OUR SPONSORS! -BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off.  -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Aly’s Website –  https://thesmarthuman.com/ • Aly's Website - https://alycohenmd.com/ • Aly’s New Book – Detoxify: https://alycohenmd.com/books • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: 00:00 Trailer 02:01 Introduction 02:15 Rheumatism and Rheumatology 03:36 Autoimmune Diseases and Toxins 04:17 Chemical Impact on Health 04:49 Personal Health Journey 06:15 Microplastics and Immune Disruption 08:21 Resilience and Lifestyle Changes 21:45 Nutritional Deficiencies 26:48 Lab Results and Assessments 34:40 Detoxification and Resilience 41:14 Personal Journey Continued 42:22 Clean Drinking Water 44:20 Travel Hacks for Water 46:15 Hotel Room Detox Tips 50:06 EPA Water Standards 53:06 Restaurant Toxins and Home Safety 55:36 Top Toxic Household Items 01:08:31 Synthetic Materials Impact 01:13:30 Final Thoughts and Book See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if you could reverse the age of your heart...without leaving home? In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer of Timeline, to reveal groundbreaking science that targets cardiovascular aging at the cellular level. You’ll discover how mitochondrial decline drives heart failure, why postmenopausal women face skyrocketing cardiac risks, and how one powerful molecule, Urolithin A, can rejuvenate your heart’s energy systems. Dr. Singh shares clinical research showing how Urolithin A improves mitochondrial function, boosts endurance, and may even reverse biological aging markers in the heart. You’ll also learn how simple lifestyle biohacks, combined with cellular nutrition, can protect your cardiovascular health and extend your healthspan. What You’ll Learn in This Episode: • The link between mitochondrial decline and heart failure • Why women’s cardiac risk skyrockets after menopause • How Urolithin A stimulates mitophagy and energy renewal • New human clinical data on reversing cardiac aging markers • Biohacking strategies to fortify your cardiovascular health • How to optimize endurance, recovery, and heart resilience  THANK YOU TO OUR SPONSORS! -STEMREGEN | Head to https://www.stemregen.co/dave for 20% off your first order.  -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial.  Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Timeline Website –  https://www.timeline.com/partners/dave-asprey • Timeline Instagram - https://www.instagram.com/timeline_longevity/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 — Trailer • 02:11 — Supplements that help • 03:05 — Long-term benefits • 04:38 — Stacking with lifestyle • 22:19 — Heart health connection • 29:39 — Mitochondria & brain function • 33:04 — Glymphatic system & Alzheimer’s • 33:53 — Bed height & brain health • 34:18 — Why mitochondria matter • 35:43 — Inflammation & dysfunction • 38:12 — Transplants & consciousness • 39:19 — Meditation’s effects • 40:33 — The ultimate biohacking stack • 43:06 — Creatine for sleep & focus • 50:00 — Fertility insights • 57:23 — Skin health • 01:00:28 — Final thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if a laser could help a child speak for the first time—or reverse an “incurable” brain condition? In this episode of The Human Upgrade, Dave Asprey talks with Dr. Brandon Crawford, a leading neurotherapist and founder of 528 Innovations, about the emerging science of laser therapy for the brain and body. You’ll learn how light—when precisely pulsed and targeted—can rewire brainwaves, heal trauma, and even influence states of consciousness. Dr. Crawford explains how specific laser frequencies are being used to modulate brain states, activate the vagus nerve, improve mood, restore gut-brain communication, and support recovery from conditions like autism and ALS. From EEG shifts to structured water and mitochondrial signaling, this conversation dives deep into biohacking’s most advanced light-based tech. What You’ll Learn in This Episode: • How laser therapy rewires brainwaves for mood, focus, and clarity • The exact brain regions linked to embodiment, intuition, and flow • Why pulsing patterns matter more than power in laser tech • How light influences trauma recovery and vagus nerve activation • The role of structured water and infrared light in cellular repair • How patients with ALS and autism responded to 528 protocols ** Get 30% off GA Virtual Tickets for the Biohacking Conference this May with code ‘528i30’ at checkout! ** THANK YOU TO OUR SPONSORS! -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.  -LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/DAVE. Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • 528 Innovations Website and used code ‘UPGRADE10’ at checkout –  https://528innovations.com/dave • 528 Innovations Instagram - https://www.instagram.com/528innovations/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 02:00 – Intro • 02:26 – New breakthroughs in laser therapy • 03:07 – Why laser tech needed reinvention • 04:21 – How laser light influences the brain • 08:03 – Holograms, light, and reality • 09:02 – Telepathy and autism connections • 12:03 – Rewiring the brain with light • 20:01 – Quantum signaling between cells • 22:33 – Biohacking and yogic practices • 22:54 – Testosterone and natural living • 23:37 – Boosting testosterone with lasers • 25:21 – Mitochondria and higher awareness • 27:35 – Laser benefits across the body • 30:29 – Advanced brain stimulation tech • 36:19 – ALS recovery and healing cases • 40:48 – Closing thoughts and next steps See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if mitochondria weren’t just energy engines — but conscious beings guiding your survival and evolution? In this episode, Dave Asprey sits down with Zach Bush, MD, to uncover a radical new science of cellular intelligence. Together, they reveal how your mitochondria, microbiome, and genetic memory do far more than support survival—they actively shape consciousness, drive healing, and accelerate human evolution. You’ll discover why chronic disease, fatigue, brain fog, and emotional trauma often trace back to lost cellular communication—and how restoring that network can unlock radical resilience, deeper energy, and true longevity. Through the lens of soil health, vibrational biology, light frequencies, and ancient microbial wisdom, Zach Bush shows why the future of biohacking demands reconnection to the deeper intelligence already alive inside you. What You’ll Learn in This Episode: • How mitochondria act as conscious messengers—not just energy factories—and why that changes everything about health and aging • Why rebuilding gut microbiome intelligence strengthens immune function, brain health, and emotional resilience • How disrupted cellular communication fuels chronic inflammation, autoimmune disease, and premature aging • How emotional trauma imprints onto genetic expression and triggers mitochondrial collapse • Why viruses and bacteria serve as evolutionary partners—not enemies—and how they upgrade your biology • How “cellular safety” activates healing, regeneration, and peak human performance • How carbon cycles, soil health, and light frequencies repair DNA and extend human lifespan • Simple daily practices that rebuild cellular coherence, boost energy, and reconnect you to your innate intelligence This conversation will rewire how you think about health, disease, and human potential—giving you the tools to upgrade your biology at the deepest level. **Check out Zach's exclusive offer for The Human Upgrade listeners at https://intelligenceofnature.com/ and use code ‘DAVE10” for a discount!** SPONSORS - ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order.  - Apollo Neuro | To get an Apollo wearable, go to https://apolloneuro.com/Dave and save 15%. Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Zach’s Website –  https://zachbushmd.com/ • Zach’s Instagram - https://www.instagram.com/zachbushmd/?hl=en • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 00:52 Intro: Microbiome and Human Connection • 03:07 Microbiome’s Role in Nutrition and Health • 05:48 Chemical Farming’s Impact on Soil and Health • 09:23 Mitochondria and Cellular Communication • 26:00 Viruses, Exosomes, and Evolution • 34:36 The Observer Effect and Reality • 40:08 Tech vs. Nature in Healing • 41:04 Light, Mitochondria, and Cellular Energy • 42:01 Choosing Tech or Natural Regeneration • 43:44 The Miracle of Life and Human Potential • 45:05 Healing Generational Trauma • 47:38 Shamanic States and Connection • 01:05:48 Sacred Geometry and Group Healing • 01:12:48 Rational vs. Mystical Perspectives • 01:14:52 Finding Common Ground • 01:15:10 Inside the Supplement Room • 01:15:47 Emerging Tech in Biohacking • 01:15:58 Non-Tech Health Upgrades • 01:16:11 Stem Cell Concerns and Cautions • 01:17:31 Nature Deficit and Health Impacts • 01:19:09 Curiosity and Personal Growth • 01:20:56 Generational Shifts and Gender • 01:24:20 Strengthening Relationships Through Differences • 01:28:31 Storytelling’s Power Over Data • 01:38:24 Longevity and Embracing Elderhood • 01:44:47 Final Thoughts and Future Visions See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

You’ve probably heard of HIIT—but have you heard of “REHIT?”  This isn’t just another workout trend...it’s a new science-backed way to train with maximum efficiency and zero wasted time. If you’re still jogging, you’re wasting hours for minimal results. In this episode of The Human Upgrade, Dave Asprey sits down with Ulrich Dempfle, German-trained engineer and co-founder of CAROL Bike, to dismantle outdated cardio advice and introduce the 5-minute protocol that’s obliterating fitness myths. Forget the treadmill grind. REHIT (Reduced Exertion High-Intensity Training) exercising delivers: • 12% VO₂ max increase• 6x the fitness gains of daily jogging • 62% drop in diabetes risk • 5x more BDNF for brain power —all with just 8 minutes of effort per week. But was it? Ulrich unpacks the hard data, crushes the Zone 2 obsession, and shows how a brand-new way of exercising is giving explosive results—no matter your age or fitness level. What You’ll Learn in This Episode: • Why Zone 2 cardio is outdated advice for most people • The science of REHIT and how 2 sprints beat 2-hour workouts • The shocking data on VO₂ max, insulin sensitivity, and lifespan • How CAROL uses AI to personalize exercise for any age or ability • Why most people fail at fitness—and how to fix it • The real role of lactate, BDNF, and HRV in recovery and resilience • How perimenopausal women benefit more from REHIT than HIIT or jogging • Why adherence—not intensity—is the #1 predictor of results • What to do when you’re traveling or don’t have access to the tech Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • CAROL Bike Website and use code ‘DAVE’ for a discount –  https://carolbike.com/ • CAROL Bike Instagram - https://www.instagram.com/thecarolbike/?hl=en • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Introduction to REHIT Training • 00:24 Meet Ulrich Dempfle: The Mind Behind CAROL Bike • 00:51 The Science and Benefits of REHIT • 01:44 Comparing Traditional Cardio to REHIT • 02:32 Dave Asprey’s Personal Fitness Journey • 03:43 The Efficiency of REHIT Training • 05:03 Practical Applications and Accessibility of REHIT • 08:22 Addressing Common Concerns and Misconceptions • 11:25 The Future of Fitness: REHIT and Beyond • 18:29 Scientific Validation and Real-World Results • 31:53 Clinical Trials and Tech Integration • 32:06 Upgrade Labs and CAROL Bike • 33:00 Mitochondrial Effectiveness and Insulin Sensitivity • 36:05 Zone Two Training vs. High-Intensity Training • 42:02 REHIT for Perimenopausal Women • 48:18 AI and Personalized Exercise • 57:52 Lactate and Exercise Benefits • 01:01:48 Interval Walking Training • 01:04:01 Conclusion and Future Insights See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Your bloodwork looks normal. Your doctor says you’re fine. But you still feel exhausted, inflamed, anxious—or worse. In this episode, Dave Asprey talks with Dr. Daniel Pompa, a leading voice in cellular detox and root-cause healing, to expose the hidden stressors hijacking your energy, hormones, and metabolism—even when your labs say you’re healthy. Dr. Pompa shares his personal health collapse and reveals how cellular dysfunction, neurotoxicity, and hormone resistance drive the chronic fatigue epidemic. If you’ve ever felt dismissed by “perfect” bloodwork, this conversation will rewire how you think about sickness—and show you how to reclaim real, lasting wellness. What You’ll Learn in This Episode: • Why your bloodwork can be “perfect” while your cells are on fire • The overlooked hormone resistances sabotaging your energy and metabolism • The 3-legged stool of chronic illness—and what actually drives disease • What “upstream detox” really means, and why most cleanses make you worse • Why toxins trigger genetic expression (and how to shut that down) • How to fix unexplainable fatigue, anxiety, and weight gain from the inside out • Why true healing starts with fixing the cell, not the symptom It’s time to stop chasing symptoms—and start upgrading from the root. **Check out Dr. Pompas EXCLUSIVE protocol built for The Human Upgrade listeners at davetestkit.com and use code ‘10OFF’ for a discount!**  SPONSORS -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.  -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order.  Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Dr. Pompa’s Website –  https://drpompa.com/ • Dr. Pompa’s Instagram - https://www.instagram.com/drpompa/?hl=en • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 00:55 Intro • 01:10 Healthy Is the New Sick • 02:27 Bloodwork & Hormone Resistance • 04:32 Dr. Pompa’s Health Collapse • 08:38 Toxins & Environmental Triggers • 15:01 Why Most Detox Fails • 29:16 The 5 Rs of Cellular Healing • 37:06 Olive Oil: Cure or Concern? • 38:11 Fat Balance for Energy • 42:13 Cholesterol & Saturated Fat • 46:26 Restoring Cellular Energy • 51:08 The Power of Diet Variation • 56:57 Plant Toxins Explained • 01:03:28 Emotional & Spiritual Detox • 01:13:55 Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most people run from stress. The world’s highest performers run toward it. Sébastien Page manages over $500 billion in global assets. He’s the CIO of one of the world’s largest investment firms, and he wrote The Psychology of Leadership while living under relentless pressure. His secret? He doesn’t avoid stress—he uses it as a tool for performance, clarity, and control. But here’s the twist: this isn’t just about boardrooms or billion-dollar trades. Whether you’re running a company, chasing a deadline, or just trying to stop procrastinating on your goals—this conversation will flip what you think you know about pressure, performance, and productivity. You’ll learn why trying to “relax your way to success” doesn’t work—and how to harness discomfort to create better decisions, higher output, and more resilience in every part of life. What You’ll Learn in This Episode: • The psychology of stress and why zero stress leads to burnout • How procrastination can boost creative performance • What astronauts, athletes, and leaders have in common • Why the key to better decisions is strategic patience, not speed • The stress-performance curve no one taught you in school • Why losing is the real path to mastery (and what Roger Federer can teach you) • The difference between being nice vs. being kind—and why it matters It's time to start turning stress into strategy. SPONSORS -fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE.  -BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino.  Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Sébastien’s New Book –The Psychology of Leadership –  https://www.psychologyofleadership.net/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com  Timestamps: • 00:00 Intro • 02:00 Book Launch & Setup • 02:45 Buy or Sell? Market Insights • 03:20 Stress and Performance • 04:28 Sports Psychology Breakdown • 09:48 Federer & the Power of Losing • 26:42 Rethinking Feedback • 31:32 Stress as a Tool • 44:10 Listening as Leadership • 44:17 Traits of Great Leaders • 44:54 Psychology for Entrepreneurs • 45:37 Leading Beyond Work • 46:09 Sleep Tracking Anxiety • 47:39 Channeling Stress • 49:04 Extreme Pressure Moments • 50:42 The Corporate Athlete • 59:08 Vulnerability & Leadership • 01:05:23 Goal-Induced Blindness • 01:12:34 Finding Meaning at Work • 01:18:08 Leadership at Home • 01:20:27 Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Your DNA, health data, and digital identity are encrypted, monetized, and weaponized against you. But what if there was a way to take it back… and hack the system? In this mind-expanding episode, Dave sits down with two elite hacker-founders—Michael Tiffany, CEO of Fulcra.ai, and Vishakh, founder of Monadic DNA—to explore a radical shift in the way we store, protect, and use our most personal data. Together, they break down the Web3 tech stack powering this revolution. Enter Nillion, a distributed, privacy-preserving compute network that allows you to share and analyze your encrypted data… without ever giving it away. From genomic privacy to AI sovereignty, this episode exposes the hidden architecture of control—and how to escape it. You’ll learn how cutting-edge blockchain and cryptography are rewriting the rules of ownership, consent, and even identity itself. What You’ll Learn in This Episode: • Why your DNA is already in government databases—and how long they keep it • How Nillion enables secure computation on private data • What it means to build a “cybernetic operating system” for your body • Why Fulcra.ai is building the orchestration layer of human optimization • How Monadic DNA helps you profit from your genetics—without giving them away • Why owning your data is the next frontier of biohacking • The surprising connection between decentralization, health freedom, and consciousness • How to join the movement toward true data sovereignty If you’ve ever felt like you’re giving away too much to big tech, big pharma, or just the internet itself—this conversation will change how you see your data… and your body. **Join the Fulca sleep study today! Visit https://fulcra.ai/sleep to sign up** **Get a 30% discount on Fulca with code “DAVE”!  SPONSORS -IGNITON | Go to https://www.biohackingconference.com/ and get your tickets while there are still great discounts available. Go to https://www.igniton.com/DAVE and use code DAVE to save 15%. -Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Fulcra Dynamics Website – https://www.fulcradynamics.com/ • MonadicDNA Website: https://monadicdna.com/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com  Timestamps: • 00:00 – Trailer • 02:01 – Intro • 02:26 – Data Privacy & AI: The Big Shift • 03:21 – Meet Michael Tiffany • 04:41 – Cybernetic Operating Systems • 05:13 – Wearables & Personal Augmentation • 08:21 – Meet Vishakh: DNA Privacy Mission • 09:25 – Why Genetic Data Needs Protection • 11:30 – New Tech: Encryption & Privacy Tools • 16:13 – How Multi-Party Compute Works • 41:58 – Emergence: Behavior & Systems • 49:11 – Meditation & Mental Reprogramming • 50:20 – Distributed Computing & Biology • 56:15 – Environment Shapes Potential • 57:57 – Empowering Individuals at Scale • 01:00:31 – Biohacking Meets Inner Awareness • 01:04:01 – The Dark Side of DIY Mind Hacks • 01:06:09 – Future of Biohacking & Community• 01:12:28 – Integrating Genetic & Life Data • 01:20:39 – Why We Started Biohacking • 01:25:01 – Favorite Current Biohacks • 01:31:41 – Final Thoughts & Resources See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

If your brain feels foggy, your mood swings like a pendulum, or your cravings seem to control you—this episode will flip what you think you know about your body and your mind. Because what if your thoughts… aren’t really yours? In this mind-altering episode of The Human Upgrade, Dr. Steven Gundry reveals a startling new theory: your gut microbiome might be controlling your thoughts. From addiction and depression to obesity and inflammation, the microbes living in your gut—bacteria, fungi, viruses, even parasites—may be pulling the strings on your brain chemistry, mood, and behavior. Dave Asprey and Dr. Gundry dive deep into The Gut-Brain Paradox, exposing how the gut-brain axis operates more like a microbial command center than a digestive system. You’ll learn why probiotic pills rarely work, how the wrong microbes can drive compulsive behavior, and how toxic foods, glyphosate, and antibiotics have turned our guts into neurological war zones. Most shocking of all? Microbes may not just influence addiction—they may cause it. What You’ll Learn in This Episode: • How your gut microbiome can hijack your brain and influence your thoughts and behavior • Why certain microbes may actually cause addiction, obesity, and depression • How antibiotics, glyphosate, and processed foods are turning your gut into a desert • How to rebuild your gut ecosystem using postbiotics, fermented foods, and precision inputs • Why food cravings might be microbial mind control—and what to do about it • What the latest science reveals about the gut-brain axis, neurotransmitters, and neuroinflammation Sponsors: -Sunlighten | Go to https://www.sunlighten.com/dave/ and enter code DAVE at checkout to save up to $1,400.  -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Dr. Gundry’s Instagram –  https://www.instagram.com/drstevengundry/?hl=en • Dr. Gundry’s Website: https://drgundry.com/ • Dr. Gundry’s New Book The Gut-Brain Paradox: https://www.barnesandnoble.com/w/the-gut-brain-paradox-steven-r-gundry-md/1146019686?ean=9780062911803 • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 — Trailer • 02:01 — Intro • 03:55 — The Gut-Brain Connection • 04:45 — Microbiome Communication and Control • 08:19 — The Role of Fungi and Plants • 11:29 — Microbiome Diversity and Health • 19:05 — Addictive Microbiome and Behavior • 28:17 — Antibiotics and Gut Health • 30:49 — Listener Concerns and Gut Health • 31:02 — Whale Watching and Climate Change • 32:58 — Understanding SIBO and Bacterial Migration • 34:02 — The Role of Soluble Fiber and Fermented Foods • 36:12 — Complexity of Gut Microbiome • 36:49 — Restoring Ecosystems and Gut Health • 38:23 — Precision Microbiome Manipulation • 41:31 — Calcium Formation and Gut Bacteria • 43:56 — Oxalates vs. Lectins Debate • 46:04 — Whole Foods and Glyphosate Concerns • 51:47 — Dopamine Levels and Gut Health • 54:59 — Conclusion and Book Promotion See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

If your hair is thinning, shedding, or simply not what it used to be—and nothing seems to work—this episode is for you. Because what if the story you’ve been told about balding… is wrong? For decades, hair loss has felt like fate: genetic, inevitable, untouchable. But science is catching up to something deeper—something root-level. What if the real culprit behind age-related hair loss is cellular dysfunction? And what if we could change that? In this episode, Dave Asprey uncovers the cellular biology of hair thinning with longevity researcher Carolina Reis Oliveira. You’ll learn how senescent cells (aka zombie cells) hijack your scalp, disrupt follicle function, and silently accelerate hair loss—and how a breakthrough peptide might stop it cold. Carolina reveals brand-new clinical research on OS-01, a molecule shown to increase hair density by 40% in just 6 months. But this isn’t a product pitch—it’s a paradigm shift. Together, they explore the hidden drivers of hair aging, from hormone shifts and stress cascades to microbiome imbalances and inflammation, plus the real science behind what can actually regrow hair. What You’ll Learn in This Episode: • How “zombie cells” (senescent cells) sabotage your hair from the inside out • The science behind the OS-01 peptide and how it reverses visible hair thinning • Why thinning hair isn’t just genetic—and what else is driving it • How stress, hormones, and aging collide to trigger follicle dysfunction • What your scalp microbiome has to do with regrowth and hair density • How to stack red light, peptides, and topicals for real, measurable results  ***Visit oneskin.co/DAVE and use code DAVE for and additional 15% off.*** Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • OneSkin Instagram –  https://www.instagram.com/oneskin.co/ • OneSkin Website: https://www.oneskin.co/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 — Trailer • 01:52 — Intro • 02:59 — Is Aging Optional for Your Scalp? • 04:03 — Understanding Scalp and Hair Aging • 05:06 — The Role of Senescent Cells in Hair Loss • 07:25 — Hormonal Influences on Hair Health • 16:10 — Peptide Solutions for Hair Thinning • 18:05 — Clinical Studies and Results • 20:29 — Future of Hair Loss Treatments • 30:16 — Nutritional and Lifestyle Factors • 36:40 — Addressing Senescent Cells and Hair Growth • 37:29 — Minoxidil: Oral vs. Topical Use • 39:32 — Personal Experience with Hair Products • 40:25 — Combining Therapies for Hair Growth • 46:06 — Nutritional Factors in Hair Health • 52:20 — Sun Exposure and Hair Health • 56:40 — Coffee and Hair Growth • 01:00:01 — Launching the New Hair Product See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if you could rewrite the code of your personality—on command? Not just cope with anxiety, overthinking, or social exhaustion… but delete the traits holding you back and install better ones? This episode challenges everything you’ve been told about identity. Dave dives deep into the science of personality change to reveal why your habits, moods, triggers, and even sense of self aren’t fixed—they’re fluid. And more importantly: they’re up for grabs. Joining him is award-winning journalist from The Atlantic, Olga Khazan, author of Me, But Better, who spent years hacking her own mind—transforming high neuroticism, social avoidance, and chronic self-criticism into calm, confidence, and connection. Her personal experiment in identity rewiring became a roadmap for anyone who wants to feel different… and live differently. You’ll uncover the hidden mechanisms behind neuroticism, reactivity, and emotional spirals—and how to override them with real-time upgrades. What You’ll Learn in This Episode: • Why your personality is a program—and how to recode it • What daily behaviors scientifically rewire anxiety, anger, and reactivity • The surprising link between identity, inflammation, and your gut • Why gratitude isn’t soft—it’s neurological jiu-jitsu • How to know if it’s your biology or your story running the show • Whether pills, psychedelics, or sleep do more to shift who you are • What to do when your inner critic won’t shut up • And how to stop being the person you never meant to become SPONSORS -LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/DAVE.  -Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off.  Resources:  • Olga’s New Book – Me, But Better: https://www.amazon.com/Me-But-Better-Science-Personality/dp/1668012545 • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Olga's Instagram –  https://www.instagram.com/olganator/?hl=en • Olga’s Website: https://olgakhazan.com/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com  Timestamps: • 0:00 — Trailer • 1:52 — Intro • 2:16 — Personality Changes and Neuroticism • 5:38 — Postpartum Personality Shifts • 10:21 — Gratitude and Cultural Beliefs • 18:13 — Anger Management and Empathy • 32:58 — Personality Traits and Boundaries • 35:46 — The Importance of Strong Boundaries • 36:07 — Personality Change as Self-Improvement • 37:22 — The Role of Medication in Personality Change • 39:18 — Brain-Body Connection and Mental Health • 43:26 — Impact of Sleep and Nutrition on Personality • 44:23 — Nicotine and Other Substances • 45:41 — Therapy and Personality Change • 46:43 — Changing Personality Through Behavior • 1:01:25 — The Role of Relationships in Personality Development • 1:04:49 — Challenges and Methods in Personality Change • 1:08:38 — The Power of Improv in Personality Change • 1:10:17 — Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Your brain isn’t broken—it’s underpowered. Energy crashes, poor sleep, brain fog, and emotional reactivity don’t just happen. You’re running on low voltage, and your mind pays the price. In this episode, Dave sits down with Dr. Patrick Porter, founder of BrainTap, to reveal how to reprogram your brain using light, sound, and guided visualization—no substances, no side effects, no BS. Dr. Porter breaks down how to activate gamma brainwaves, repair trauma loops, access psychedelic-like states, and boost cognitive performance by 19% in just six weeks. You’ll learn why most brains burn out decades too soon—and how to charge yours back up. What You’ll Learn in This Episode: • How to flood your brain with energy and wake it up • The light and sound protocol that mimics psychedelics—safely • What gamma brainwaves unlock—and how to generate them on demand • Why your default mode network traps you in stress and distraction • The BrainTap protocol that improved cognition by 19% in 6 weeks • A real-life transformation story that rewrote one woman’s fate • The link between sleep, trauma, brain states, and performance • How to build a brain that performs like it’s decades younger This episode gives you a playbook to reclaim your focus, deepen your rest, and experience the full range of human consciousness—without touching a drug. Turn your brain on. Then turn it up. SPONSORS -STEMREGEN | Head to https://www.stemregen.co/dave for 20% off your first order.  -BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off.  Resources:  • Biohacking Conference 2025 (May 28th-30th in Austin): https://biohackingconference.com/2025 (use code BRAINTAP to save 30% on General Admission and Virtual Tickets)• Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • BrainTap Instagram: https://www.instagram.com/braintaptech/?hl=en • BrainTap Website: https://braintap.com/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 00:35 – Intro • 00:50 – Meet Dr. Patrick K. Porter and BrainTap • 01:28 – The Science Behind Light and Sound Therapy • 03:38 – Quantum Biology and Frequency Medicine • 04:32 – Enhancing Cognition with Sound and Light • 06:19 – Biohacking Conference Highlights • 08:07 – Transformative Stories and BrainTap Benefits • 17:54 – The Role of Gamma Waves and Psychedelics • 26:55 – Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

You think you’re helping your kid. You clear the path. You smooth the bumps. You make sure they never feel too sad, too bored, too uncomfortable. It feels like love. But what if it’s making them weak? In this episode, Dave Asprey sits down with bestselling author, TED speaker, and resilience expert Jennifer Cohen to reveal how today’s parenting norms are quietly producing the most anxious, dependent, and emotionally fragile generation in history—Gen Z. Whether you’re raising kids, managing young employees, or trying to understand the next generation—you’ll walk away from this episode with a new lens on resilience, responsibility, and real-world readiness. What You’ll Learn in This Episode: • Why Gen Z struggles with anxiety, confidence, and failure • How smartphones, safe spaces, and overparenting weaken resilience • The science behind boredom, chores, and grit-building discomfort • Why participation trophies are doing real psychological harm • The bold parenting shifts that build strong, adaptable adults • How to model strength—even when it’s unpopular • The simple framework to raise kids who can thrive, not just survive If you want to raise strong kids—or work with a generation that’s struggling—this episode is a must-listen. It’s not just about parenting. It’s about the future. And it starts with getting uncomfortable. SPONSORS -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial.  -Qualia | Go to https://www.qualialife.com/dave15 to get an additional 15% off subscriptions.  Resources:  • A Day of Biohacking and Consciousness Even (4/12): https://daveasprey.com/biohacking-and-consciousness/ • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Jennifer’s Instagram: https://www.instagram.com/therealjencohen/ • Jennifer’s Podcast: https://www.youtube.com/channel/UCBuPgI8lXTmy5T0D_EDMnVg • Jennifer’s Website: https://www.jennifercohen.com/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 01:59 – Intro • 03:38 – The Shift in Parenting Styles • 07:04 – The Role of Technology and Social Media • 10:59 – The Importance of Failure and Resilience • 13:38 – Practical Parenting Tips and Challenges • 24:06 – The Value of Chores and Responsibility • 26:24 – Balancing Luxury and Adversity in Parenting • 27:01 – Teaching Kids to Embrace Failure • 28:00 – The 10% Target: Encouraging Persistence • 29:35 – The Importance of Boredom and Creativity • 30:58 – Role Modeling Healthy Habits • 31:43 – Kids’ Reactions to Fast Food • 32:49 – Extreme Parenting: Biohacking and Kids • 36:30 – Rejection Therapy and Boldness • 42:42 – Praising Effort Over Intelligence • 45:32 – Challenges of Being Attractive and Intelligent • 49:31 – Instilling Self-Esteem in Children • 50:13 – Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

For decades, gut health was reduced to yogurt commercials and vague promises from probiotics that barely worked. But what if we’ve been targeting the wrong bugs, using the wrong delivery, and ignoring the true source of chronic inflammation and accelerated aging? In this thought-provoking episode, Dave sits down with Hannah Kleinfeld, a leader in microbiome innovation, to expose why most probiotics fail—and how one company’s scientifically validated approach could redefine your gut, brain, immune system, and even your metabolism. You’ll learn how dysbiosis may be wrecking your brain without you knowing it, why your probiotic likely died in your stomach acid, and the secret to rebooting your microbiome after antibiotics, GLP-1 drugs, or years of toxic exposure. This isn’t just about digestion—your gut controls your cravings, energy, sleep, mood, and aging trajectory. So what’s the one upgrade that can actually reset your gut… for good? What You’ll Learn in This Episode: • Why your gut—not your brain—is making most of your decisions • How 93% of probiotics on the market fail before they reach your intestines • The “AB 10” protocol that rebuilds your gut after antibiotics or SIBO • What GLP-1 weight-loss drugs are doing to your microbiome (and how to stop it) • The shocking gut–brain–heart axis connection you’ve never heard of • Why inflammation, brain fog, and mood swings may start with leaky gut • Which probiotic strains are clinically proven to improve cognition and mood • What to do if you want to eat gluten again—or survive American wheat • How a fermented papaya concentrate could replace your acid reflux meds • Why optimizing your gut could extend your lifespan by 40% ***Get 20% off your next purchase by going to https://omnibioticlife.com/pages/dave-asprey/ or omnibioticlife.com/dave***  SPONSORS -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.  -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.  Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • OMNi-BiOTiC's Instagram –  https://www.instagram.com/fatty15/ • OMNi-BiOTiC's Website: https://omnibioticlife.com/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 03:15 – Intro • 05:05 – Probiotics, Prebiotics, and Postbiotics Explained • 08:21 – The Importance of Delivery Mechanisms • 17:36 – Addressing SIBO and Gut Health Protocols • 31:55 – The Impact of GLP-1 Drugs on Gut Health • 39:26 – The Role of Gut Bacteria in Hunger and Fasting • 40:01 – Painkillers and Gut Health: A Personal Experience • 40:51 – The Dangers of Proton Pump Inhibitors • 42:00 – The Importance of Stomach Acid • 44:55 – Probiotics for Chronic Conditions • 48:38 – The Impact of Glyphosate on Gut Health • 57:04 – Alcohol and Gut Bacteria • 01:02:01 – New Solutions for Acid Reflux • 01:07:57 – The Future of Gut Health and Longevity • 01:11:33 – Conclusion and Special Offer See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

For nearly a century, scientists believed we had discovered ALL of the essential fatty acids the human body needs. But what if they were wrong? Stephanie Venn-Watson, a veterinary epidemiologist and longevity researcher, joins Dave to reveal a groundbreaking discovery—a newly identified essential fatty acid, C15, that may hold the key to healthier aging and even longer lifespans. Originally uncovered in an unlikely place—U.S. Navy dolphins that were outliving their wild counterparts by decades—this forgotten fat is now shaking up the scientific community. So why hasn’t anyone told you about it?? Decades of misguided dietary advice stripped this crucial nutrient from our food system, leaving an entire generation unknowingly deficient. Even worse, pregnant women have been some of the MOST hurt from this cruel change to our modern diet. Now, cutting-edge research is proving that C15 plays a critical role in cellular stability, mitochondrial function, and total mental health. What You’ll Learn in This Episode: • The first new essential fatty acid discovered in nearly 100 years—and why it matters • How dolphins led to one of the BIGGEST breakthroughs in human nutrition • Why the removal of C15 from our diets is accelerating aging • The surprising connection between C15 and mental health • How this “missing” fat could outperform some of the biggest longevity drugs today! • What foods naturally contain C15—and should you supplement it? *** Get 15$ off Fatty15 at www.fatty15.com with code: DAVE *** SPONSORS Puori | Visit https://puori.com/dave and use code DAVE for 20% off.Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Fatty15 Instagram – https://www.instagram.com/fatty15/ • Fatty15 Website: www.fatty15.com • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: 00:00 – Intro 00:34 – Meet Dr. Stephanie Venn-Watson 00:46 – Discovering C15 in Navy Dolphins 01:58 – Challenges and Skepticism 04:21 – Scientific Validation and Research 06:59 – C15’s Impact on Human Health 27:43 – Big Data, AI, and Longevity Research 36:08 – C15 as a Longevity Nutrient 42:14 – The Navy’s Role in Fatty 15 43:03 – Epigenetic Aging and Lifespan 44:51 – Nutritional Guidelines and C15 Deficiency 50:41 – Mental Health and Endocannabinoids 51:33 – Dairy, Fats, and Nutrition History 56:38 – Fatty 15 in Skincare and Supplements 01:03:58 – Regulatory Changes in Nutrition 01:11:26 – Gender Differences in Fatty Acids See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

You think you’re optimizing your brain—but what if the real culprit behind your brain fog, anxiety, and burnout is the modern world itself? In this episode, Columbia University psychiatrist and nutritional neuroscience pioneer Dr. Drew Ramsey joins Dave Asprey to decode the biological chaos hijacking your mind—and how to fight back. From inflammation and gut dysbiosis to screen-induced disconnection and hidden trauma, this is the ultimate roadmap for healing the modern brain. You’ll explore the cutting-edge science of neuroplasticity, discover how movement and social connection trigger brain growth, and learn why food is still your most powerful antidepressant. Plus: dancing, psychedelics, kale debates, and why porn is quietly reshaping the male brain. What You’ll Discover in This Episode: • Why brain fog, anxiety, and mood swings might be signs your brain is inflamed • How movement—especially dancing—can literally help your brain grow stronger • What your gut has to do with your mental health (and why some “healthy” foods can backfire) • The truth about antidepressants, supplements, and why there’s no one-size-fits-all fix • Why porn, ultra-processed food, and doomscrolling are silently wrecking focus and drive • A new way to think about mental fitness—like a workout plan for your brain SPONSORS -BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino.  -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.  Resources:  • A Day of Biohacking and Consciousness Event April 12th: https://daveasprey.com/biohacking-and-consciousness/ • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Drew’s Instagram: https://www.instagram.com/drewramseymd/?hl=en • Drew’s Linktree: https://shorturl.at/CIIR5 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 01:43 – Intro • 02:51 – The State of Mental Health Today • 04:00 – Nutritional Psychiatry and Personal Experiences • 05:21 – Environmental Factors and Brain Health • 05:55 – Chemical Balance and Psychiatry • 09:19 – Mental Fitness and Connection • 14:17 – Modern Brain Challenges • 16:26 – The Role of Movement and Dance • 22:44 – Sex, Relationships, and Mental Health • 34:02 – Microbiome and Mental Health • 36:50 – Transitioning to Urban Life and Mental Health • 37:29 – The Role of Nature in Mental Well-being • 38:14 – Personal Experiences with Gut Health • 39:45 – Trial and Error in Mental Health • 42:16 – Cognitive Resilience and High Performance • 45:37 – The Importance of Family Meals • 46:33 – Challenges of Rural and Urban Living • 47:53 – Brain Health: Beyond Neurons • 49:01 – Neuroplasticity and Mental Fitness • 52:50 – Biohacking Mental Health • 57:31 – The Role of Serotonin in Depression • 01:03:57 – Debating the Benefits of Kale • 01:12:03 – Final Thoughts on Mental Health and Resilience See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

You think, you feel, you are—but what if your consciousness isn’t just in your brain? What if reality itself is shaped by something beyond the physical? In this episode, Mark Gober—author, consciousness researcher, and former Silicon Valley banker—joins Dave Asprey to challenge everything you think you know about the mind, reality, and human potential. He explores groundbreaking research on near-death experiences, psychic phenomena, and why some scientists believe consciousness may exist beyond the body. Mark reveals how declassified CIA documents, quantum physics, and meditation practices point to a deeper, more interconnected world—one where perception creates reality. If you’ve ever questioned whether free will is an illusion, wondered about life after death, or wanted to tap into higher states of awareness, this episode will shift your perspective. What You’ll Discover in This Episode: • Is consciousness non-local? Why your brain might not be the source of your thoughts • Near-death experiences & life after death—the science and firsthand accounts • Psychic phenomena & remote viewing—what the CIA doesn’t want you to ignore • Float tanks, meditation & altered states—how to access expanded awareness • The AI consciousness debate—can machines ever become truly self-aware? • Protecting your energy—why spiritual safeguards matter when exploring altered states  SPONSORS -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. -fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE.  Resources:  • A Day of Biohacking and Consciousness Event April 12th: https://daveasprey.com/biohacking-and-consciousness/ • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Mark’s Instagram: https://www.instagram.com/markgober_author/ • Mark’s Website: https://www.markgober.com/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: 00:00 - Trailer 00:50 - Intro 03:11 - Meet Mark Gober 05:25 - From Banking to Awakening 10:16 - Float Tanks & Consciousness 12:35 - Psychic Phenomena 19:14 - Science & Skepticism 25:51 - Personal Experiences 40:51 - Spiritual Protection 42:58 - Parasitic Entities 44:59 - Psychedelics & Mindset 45:58 - Alien Abductions 47:04 - Navigating Psychedelics 51:58 - Intuition & Inner Knowing 58:41 - Telepathy & Remote Viewing 59:46 - Near-Death Experiences 01:04:54 - Consciousness Beyond the Brain 01:12:38 - Psychic Abilities & Ethics 01:24:11 - Consciousness & Reality 01:27:58 - Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

You hold the door open. You say yes when you mean no. You put others first—always. It feels like the right thing to do… but is it costing you more than you realize? In this episode, Scott Barry Kaufman, Ph.D.—Columbia professor, psychologist, and author of Rise Above—joins Dave Asprey to expose the psychology of victim vs. empowerment mindsets. He reveals how toxic altruism, external validation, and emotional fragility keep people stuck—and how you can reclaim your confidence, set boundaries, and create a life of true growth. Dr. Kaufman, one of the world’s most cited scientists, shares cutting-edge research on self-actualization, resilience, and the hidden mental loops that shape your success. If you’ve ever felt stuck in self-doubt, drained from over-giving, or afraid to take up space, this conversation will help you break free. What You’ll Discover in This Episode: • Victim vs. empowerment mindset—the key shift that changes everything • The psychological traps of toxic altruism—and why over-giving holds you back • How people-pleasing rewires your brain—and how to break the cycle • The science of self-actualization—how to unlock your full potential without guilt • Why modern culture and social media reward emotional fragility—and how to rise above it • The neuroscience behind confidence, resilience, and making better choices for YOUR growth If you’ve ever felt stuck, undervalued, or drained from always being “nice”, this episode will show you how to step into your power, rewrite your mental programming, and take control of your future. SPONSORS -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources:  • A Day of Biohacking and Consciousness Event: https://daveasprey.com/biohacking-and-consciousness/ • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Scott’s Instagram: https://www.instagram.com/scottbarrykaufman/?hl=en • Scott's New Book – Rise Above:https://scottbarrykaufman.com/books/rise-above/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 00:44 Intro  • 02:02 Rise Above – Scott’s New Book • 03:13 Triggers and Mind Control • 05:12 Victimhood and Self-Actualization • 12:01 Curiosity Over Fear • 16:32 The Power of Discernment • 26:32 Emotional Resilience Today • 31:12 The Fragility of Younger Generations • 37:33 Social Pressures and Identity • 39:47 Social Media and Self-Determination • 40:35 Community and Belonging • 42:42 Activating Happiness and Growth • 44:43 Gratitude and Daily Practices • 51:48 Healthy Selfishness vs. Altruism • 58:56 Codependency and Vulnerable Narcissism • 01:04:57 The Dark Triad and Personality Types • 01:09:14 Final Thoughts and Book Recs See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What do vibrations and the psychedelic experience have in common? MDMA therapy is revolutionizing mental health treatment, helping people overcome PTSD, anxiety, and emotional trauma with unprecedented success. But what if you could tap into those same powerful benefits—without taking a single drug? It turns out your brain responds to more than just chemistry. Vibration, frequency, and rhythm have been shaping human consciousness for millennia—from ancient chanting rituals to modern neuroscience breakthroughs. Could the right vibrations unlock the same neuroplasticity and healing pathways as psychedelics? In this episode, Dave Asprey sits down with Dr. Dave Rabin, a neuroscientist, psychiatrist, and psychedelic researcher, to explore how vibrations can rewire your brain, enhance neuroplasticity, and even mimic the effects of MDMA therapy. Dr. Rabin’s work led to the creation of Apollo Neuro, a wearable device that taps into your nervous system’s natural ability to regulate stress, boost focus, and accelerate recovery—without pharmaceuticals. What You’ll Discover in This Episode: • How specific vibrations trigger deep relaxation and neuroplasticity • Why MDMA therapy works—and how vibration-based tech can simulate it • The surprising science behind music, frequency, and altered states • How Apollo Neuro enhances sleep, focus, and emotional resilience • The overlooked role of heart rate variability in longevity and health • Why stress is the biggest obstacle to healing—and how to override it  **Apollo Neuro | To get an Apollo wearable, go to https://apolloneuro.com/Dave and save 15%**  Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Apollo Neuro Instagram: https://www.instagram.com/apolloneuro/?hl=en • Apollo Neuro Website: https://apolloneuro.com/Dave • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: 00:00 Trailer 00:40 Intro 01:18 Exploring Vibration in Biohacking 02:29 Introduction of Dr. Dave Rabin 02:53 Understanding Vibration and Its Impact 04:47 The Apollo Neuro Device 08:44 Using Apollo for Different States 11:41 Apollo in Psychedelic Therapy 24:32 Clinical Trials and Studies on Apollo 29:32 Heart Rate Variability and Biohacking 33:02 Revolutionizing Sleep with Apollo 34:40 Apollo’s Long-Term Effects and Dependency 37:16 Apollo’s Impact on ADHD and Psychiatric Disorders 45:22 The Importance of Human Connection and Simple Solutions 49:56 Longevity, Healthspan, and Future Innovations 57:23 Final Thoughts and Discount Offer See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Your Brain is Lying to You—Here’s How to Take Back Control Every day, your brain is running subconscious scripts—hidden mental loops that shape your decisions, habits, and even your self-worth. But what if those loops are sabotaging you? In this episode, Bizzie Gold, mind architect and creator of The Break Method, joins Dave Asprey to expose the self-deception patterns controlling your thoughts—and how to reprogram your brain for true transformation. Bizzie’s method isn’t just another self-help philosophy. It’s science-backed, no BS, and engineered for results. From subconscious conditioning to emotional addiction cycles, you’ll learn the exact framework for breaking free from limiting beliefs and upgrading your mind. What You’ll Discover in This Episode: • The hidden mental loops sabotaging your success (and how to break them) • The science of self-deception—why your brain lies to you daily • How early childhood experiences hardwire your thoughts and emotions • The brain’s rejection vs. abandonment patterns—which one rules you • How to use E.L.I. questions to disrupt negative thinking instantly • The AI-powered brain upgrade that could change self-improvement forever If you’ve ever felt stuck in repetitive thought patterns, bad habits, or emotional cycles, this episode will give you the blueprint to take back control of your mind. Listen now—because your brain won’t fix itself. SPONSORS -Omni-Biotic | Visit omnibioticlife.com/dave and use code DAVE20 for 20% off.  -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.  Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Bizzie Gold’s Instagram: https://www.instagram.com/bizziegold/ • Bizzie Gold's Website: https://bizziegold.com/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 00:28 – Intro • 01:39 – Understanding self-deception and its impact • 05:41 – The role of childhood trauma in shaping perception • 14:20 – Brain pattern spectrum and human behavior • 22:26 – Spiritual perspectives on DNA and past lives • 34:45 – Sharing knowledge from the ether • 34:54 – A surprising encounter with a professor • 35:43 – Healing and accessing intuition • 36:39 – The power of intuition in practice • 38:15 – Spiritual technology and Big Pharma • 39:54 – The role of self-trust in intuition • 40:49 – Understanding instinct vs. intuition • 42:17 – The E.L.I. framework for intuition • 45:50 – Hacking the brain’s language system • 57:04 – Parenting for emotional resilience • 01:06:13 – AI and emotional hacking • 01:11:01 – Conclusion and final thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Is the Way You Speak Limiting How You Think?For years, scientists debated how language shapes the brain, but new research reveals it goes far beyond communication. Some languages lack numbers, grammar, or even complex sentences—yet their speakers navigate reality in ways that defy expectations.In this mind-bending episode, linguist Daniel Everett, known for challenging Noam Chomsky’s theories, shares how his time with the Pirahã people reshaped our understanding of language, cognition, and even consciousness.If language rewires thought, what happens when AI starts using it? Can a machine truly think? And what if whales, with their massive brains, have a language of their own?What You’ll Discover in This Episode: • The hidden power of language—why learning a new one literally reshapes your brain • The Piraha people’s mind-blowing approach to communication and what it reveals about human thought • Can AI truly “think” in language, or is it just an advanced mimic? • How your environment affects memory, navigation, and cognitive function • The psychedelic connection to language evolution—could altered states have unlocked speech? SPONSORS• Puori | Visit https://puori.com/dave and use code DAVE for 20% off.• BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off.Resources:• Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/• Dan Everett’s Website: https://daneverettbooks.com/• 2025 Biohacking Conference: https://biohackingconference.com/2025• Danger Coffee: https://dangercoffee.com• Dave Asprey’s Website: https://daveasprey.com• Dave Asprey’s Linktree: https://linktr.ee/daveasprey• Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com• Own an Upgrade Labs: https://ownanupgradelabs.com• Upgrade Labs: https://upgradelabs.com• 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

For decades, we’ve been told that our DNA is a fixed blueprint—an unchangeable code that dictates our health and lifespan. But what if that’s only half the story? Sharon Hausman-Cohen, a physician, researcher, and genomics expert at IntellxxDNA, joins Dave to reveal the cutting-edge science of genetic optimization—how understanding your DNA can unlock longer life, better brain function, and even protection from chronic disease. Forget the old-school genetic reports that left you with useless percentages. The new frontier of precision genomics goes beyond risk factors to actionable insights, showing you exactly how to turn on your body’s most powerful longevity genes and turn off the pathways driving inflammation, cognitive decline, and disease. What You’ll Learn in This Episode: • Why genetics alone don’t determine your future—and how to use epigenetics to control your health • The truth about MTHFR, APOE4, and other “bad” genes—are they actually harming you? • How genetic reports can predict and eliminate brain fog, fatigue, and pain • The hidden genetic reasons behind ADHD, depression, and anxiety—and how to fix them • Why some people age faster—and the one longevity gene that determines your biological age • Cutting-edge breakthroughs in DNA-based biohacking—is it possible to edit your genes for peak performance? This is the future of personalized medicine. By understanding your own genetic blueprint, you can stop guessing and start making the precise changes that will optimize your energy, brainpower, and lifespan! ** Visit IntellxxDNA at https://intellxxdna.com/asprey/ When you go to the website to find a clinician please select “human upgrade/longevity” as the type of consult to get specialized biohacking clinicians! ** SPONSORS -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. -Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off.  Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • IntellxxDNA Website: https://intellxxdna.com/asprey/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Intro • 02:00 – The Role of Genetics in Longevity • 03:37 – Gene Variants & Cognitive Health • 05:58 – Epigenetics vs. Genetics • 08:21 – Genomics & Pain Management • 09:26 – Breakthroughs in Genetic Research • 12:33 – The Future of Genomic Medicine • 14:27 – How to Use Genomic Reports • 38:25 – Mitochondria & Longevity • 42:40 – BH4 & Mental Health • 43:42 – Folinic Acid & Brain Function • 44:37 – Genomics & Autism • 46:06 – Personalized Medicine • 56:00 – APOE4 & Alzheimer’s Risk • 59:44 – Genetics & Heart Health • 01:04:54 – The Future of Precision Medicine • 01:20:23 – Conclusion & Next Steps See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

For years, we’ve been told that willpower and repetition are the keys to forming habits. But the truth is, habits don’t stick because of repetition—they stick because of emotion! In this all-time classic episode, Dave brings together two of the world’s top habit experts—BJ Fogg, PhD, and James Clear—to break down the real science of behavior change. BJ, the Stanford researcher behind Tiny Habits, explains why motivation, ability, and the right prompts are the real drivers of habits. Meanwhile, Atomic Habits author James Clear reveals how small decisions compound over time to shape your entire life. What You’ll Learn in This Episode: • Why willpower and repetition don’t work—and what actually makes habits stick • The tiny changes that create massive, lasting results • How emotions play a bigger role in habit formation than you think • The hidden power of stacking small habits for exponential growth • How to automate your decisions to free up brainpower for bigger goals SPONSORS -STEMREGEN | Head to https://www.stemregen.co/dave for 20% off your first order. -LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/DAVE.  Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • BJ Fogg’s Website –  https://www.bjfogg.com/ • James Clear’s Website: https://jamesclear.com/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com  Timestamps: • 00:00 – Intro  • 00:39 – Understanding habits • 01:10 – Layering habits with James Clear • 01:49 – BJ Fogg’s Tiny Habits method • 03:03 – The science of habit formation • 05:49 – Practical habit-building tips • 09:57 – Emotions vs. repetition in habits • 18:02 – Ability & context in habits • 21:19 – Genes, dopamine & behavior • 26:20 – Final thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this first-ever AMA episode, Dave tackles your biggest biohacking questions—straight from The Upgrade Collective! From optimizing brain power to pushing the limits of cold therapy, this episode is packed with cutting-edge hacks to supercharge your body and mind. If you’d like to have your questions answered on the next AMA, click the link below for details on The Upgrade Collective membership, and get all sorts of extra biohacking add-ons for your life! In today’s episode: What if you could amplify oxytocin—the “love hormone”—to build stronger relationships and lower stress? Or upgrade your cold plunge routine for max benefits in less time? Dave reveals the science behind these powerful biohacks, plus his take on rapamycin for longevity, the right way to supplement for thyroid health (without a prescription), and even how he personally overcame Asperger’s traits through neuroplasticity and mitochondrial upgrades. There’s even some great advice for all the parents out there! What You’ll Learn: • How to naturally boost oxytocin for better relationships and emotional health • The fastest way to upgrade your cold plunge for heat shock benefits • Is rapamycin really a longevity miracle? Dave’s personal take • How mitochondria impact brain power, mood, and aging—and how to fix them today! • The shocking reason some people can’t process reality correctly (and how to retrain your brain) • The real truth about stem cells, exosomes, and V-cells for regeneration • The hidden dangers of selenium, thyroid supplements, and over-fasting SPONSORS -Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide.  -Calroy | Head to https://calroy.com/dave for an exclusive discount.  Resources:  • Upgrade Collective Membership: https://www.ourupgradecollective.com • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Intro • 00:37 – Welcome to the Human Upgrade AMA • 01:13 – Cold Plunges and Alpha Lipoic Acid for Health • 03:11 – Hot and Cold Therapy for Optimal Health • 07:29 – Understanding Thyroid Health and Treatment • 09:09 – The Importance of Selenium • 14:41 – Stem Cells vs. Exosomes • 16:27 – Rapamycin for Longevity • 18:07 – Asperger’s Syndrome and Neuroinflammation • 28:53 – Understanding Asperger’s and Self-Awareness • 29:24 – The Challenge of Offering Help • 30:06 – The Importance of Reconnection Work • 31:34 – Personal Development Journey • 34:42 – The Role of Emotions in Biohacking • 35:55 – Dealing with Flashbacks and Trauma • 45:46 – The Power of Oxytocin • 49:48 – The Truth About Kale and Oxalates • 54:25 – Teaching Kids to Regulate Their Nervous System See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Can You Mimic Fasting—Without Actually Fasting? Chris Rhodes, a biochemist and longevity researcher, joins Dave to reveal a groundbreaking fasting mimetic that could revolutionize how we approach aging, metabolism, and health. Fasting is one of the most powerful tools for longevity, but what if you could achieve the same benefits without hunger, energy crashes, or social sacrifices? Scientists have identified key compounds that mimic fasting at the cellular level—offering a way to extend lifespan, boost metabolism, and enhance cognitive function without giving up food. Enter Mimio, a blend of four key molecules naturally produced during fasting, is engineered to deliver the life-extending benefits of fasting—without starvation. For decades, fasting has been the gold standard for longevity, but over-fasting can wreck hormones, metabolism, and muscle mass. So, what if you could get the benefits of a 36-hour fast without the downsides? Chris breaks down the science behind fasting, autophagy, and the game-changing compounds that trick your body into entering a fasted state—even while eating. What You’ll Learn: • The optimal fasting window for maximizing lifespan (Hint: It’s not 16 hours) • The four fasting metabolites that extend life by 96% • How Mimio mimics fasting benefits—without giving up food • The real reason over-fasting destroys your metabolism and hormones • Why traditional longevity drugs (Metformin, Rapamycin) fall short • Can you build muscle and burn fat at the same time? The science of mTOR & AMPK • Why Big Pharma doesn’t want you to know about this breakthrough *** Get 20% off Mimio at mimiohealth.sjv.io/3J9abX with code: DAVE *** Sponsors:Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial.Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order.Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Mimio Instagram:  https://www.instagram.com/mimiohealth/ • Mimio Website:  https://mimiohealth.com/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Intro • 00:58 – Fasting & Longevity • 01:88 – Optimal Fasting Length • 03:39 – Alternate Day Fasting: Pros & Cons • 05:50 – Key Fasting Compounds • 07:34 – Spermidine & Longevity Molecules • 11:41 – FDA Roadblocks on Natural Compounds • 15:37 – AI, Big Data & Longevity Research • 31:19 – Mimio’s Impact on Testosterone & Aging • 35:16 – Longevity & Death Philosophy • 36:48 – Biohacking Origins • 37:03 – Metabolism & Cognitive Function • 38:35 – Unexpected Effects of Fasting • 40:43 – Fasting & Circadian Rhythms • 43:09 – Mimio Science & Benefits • 45:14 – Mimio in a Daily Routine • 55:05 – Men vs. Women: Fasting Differences • 01:02:23 – Future of Nutrition & Biohacking • 01:07:21 – Conclusion & Discount Code See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Could a single molecule be the difference between vibrant longevity and early decline? Dr. Andrew Salzman—Harvard-trained physician, scientist, and creator of the first PARP1 inhibitor, Chief Medical Officer of Wonderfeel—joins Dave to reveal the real key to living longer, fighting disease, and maximizing your energy: NAD. This master molecule fuels your mitochondria, DNA repair, and cellular resilience, but here’s the catch—it plummets as you age. That means more fatigue, brain fog, inflammation, and higher risks of disease. But what if you could stop the decline and even reverse it? Dr. Salzman breaks down the game-changing science behind NAD, CD38, and cellular repair—and the fastest, most effective ways to optimize your levels for peak performance, health, and longevity. Get ready to rethink everything you thought you knew about aging, pharmaceuticals vs. supplements, and the radical new approach to living better, longer. What You’ll Learn: • The #1 reason your NAD is disappearing—and how to fix it • Why NAD is the missing link in energy, DNA repair, and disease prevention • The hidden enzyme (CD38) that’s sabotaging your longevity • How to supercharge mitochondria, optimize blood flow, and fight aging at the source • Why the supplement industry has it wrong—and the best way to boost NAD naturally • The shocking truth about the FDA, pharmaceuticals, and the future of anti-aging medicine Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Wonderfeel Instagram –  https://www.instagram.com/getwonderfeel/  •  Wonderfeel Supplement :  https://getwonderfeel.com/product/wonderfeel-youngr-nmn/?utm_source=Dave&utm_medium=podcast • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: 00:00 Trailer 01:07 Introduction and Episode Overview 02:29 Meet Dr. Andrew Salzman 02:36 From Physician to Researcher 03:39 Pharmaceuticals vs. Nutritionals 04:17 The Role of NAD in Longevity 06:32 Challenges in Longevity Research 12:58 Understanding NAD and PARP 14:34 NAD’s Impact on Health 23:19 Gut Health and Longevity 27:43 Innovations in NAD Supplementation 41:27 Customer Feedback and Product Effectiveness 42:41 Surprising Benefits of NAD for Sexual Health 44:47 NAD and Vascular Health 48:46 NAD’s Role in Aging and Longevity 54:03 NAD and Lifestyle Choices 01:03:02 NAD and Cognitive Function 01:06:18 NAD and Exercise 01:13:42 NAD and Sleep 01:21:54 Final Thoughts on NAD and Longevity See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Welcome to the metabolism masterclass!Dr. Ben Bikman (Ph.D Professor BYU), a powerhouse in metabolism science, joins Dave to expose the truth about insulin resistance—the silent epidemic fueling obesity, chronic disease, and low energy. Forget the outdated calorie-counting nonsense (it doesn’t work)—Dr. Bikman reveals how your hormones, not just your diet, control your metabolism and what you can do to reset it fast. From debunking diet myths to uncovering why some people can eat 400 grams of carbs and never gain fat (hint: it’s not what you think), this episode unpacks the real science of fat storage, energy, and optimal health. Get ready for mind-blowing insights, metabolic hacks, and a new way to think about food, fasting, and longevity. What You’ll Learn: • The #1 driver of insulin resistance—and why most doctors miss it • Why eating more fat (yes, really) could be the key to reversing metabolic dysfunction • How fasting, cold therapy, and red light impact your metabolism • The truth about carbs, seed oils, and why some people can’t gain fat • How to tell if insulin resistance is wrecking your energy & health  Resources:  • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ •  Benjamin’s new book How Not To Get Sick :  https://a.co/d/aADlMWv • Benjamin’s YouTube Page –  https://www.youtube.com/@benbikman • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com SPONSORS:  -Lumiram | Go to http://healthlighting.com/dave to save 10% on your order. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Timestamps: 00:00 Trailer 00:52 Introduction to Dr. Benjamin Bikman 02:20 The Battle Against Conventional Dietetics 04:12 Understanding Insulin Resistance 06:29 The Two Paths to Insulin Resistance 10:19 Fasting and Metabolic Health 14:11 Insulin and Cognitive Enhancement 18:16 Identifying Insulin Resistance 30:12 The Role of Insulin in Fat Storage 42:04 Understanding Glucose and Insulin Dynamics 42:26 The Role of Exercise in Glucose Regulation 42:54 AMPK and Muscle Contraction 45:21 Calories In, Calories Out Debate 46:15 The Myth of Calorie Counting 50:13 Ketosis and Metabolic Rate 51:14 Intermittent Fasting and Muscle Preservation 55:21 Insulin Resistance and Ketogenic Diets 01:02:04 Circadian Rhythm and Insulin Sensitivity 01:08:08 Environmental Toxins and Insulin Resistance 01:13:03 The Impact of Seed Oils on Insulin Resistance 01:19:22 Final Thoughts and Resources See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most people wait for inspiration. But what if you could train your brain to create on demand? Rick Rubin has spent decades shaping the sound of legendary artists—Jay-Z, Johnny Cash, Metallica, and countless others—by tapping into the unseen forces of creativity. But what’s the secret behind his genius? In this must-listen episode, Rick sits down with Dave to explore the science and soul of creativity, revealing how meditation, mindfulness, biohacking, and unconventional thinking fuel artistic breakthroughs. From rewiring your brain with meditation to stacking biohacks for peak creative flow, Rick shares the techniques that have kept him at the top of the music industry for over 40 years. Dave and Rick go deep on the mental and physiological hacks that enhance creative performance, the surprising link between biohacking and artistry, and the rituals that keep Rick sharp, focused, and endlessly inspired. What You’ll Learn: • How Rick Rubin taps into creative flow—and how you can too • The surprising connection between meditation and peak artistic performance • Why biohacking isn’t just for longevity—it’s for creative mastery • Rick’s favorite tools for mental clarity, focus, and creative breakthroughs • The real secret behind working with the world’s biggest artists • How to cultivate an environment that fuels creativity Resources:  • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Rick’s New Book The Creative Act: A way of Being: https://a.co/d/2bLbjeS   • Rick’s Instagram: https://www.instagram.com/rickrubin/?hl=en • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com SPONSORS:  Omni-Biotic | Visit omnibioticlife.com/dave and use code DAVE20 for 20% off.  BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino. Timestamps: • 00:00 – Trailer • 00:51 – Intro to Rick Rubin • 02:51 – Rick’s Musical Journey • 03:06 – The Creative Process • 08:31 – Biohacking & Sensitivity • 13:46 – Meditation & Creativity • 19:37 – Rick’s Weight Loss Story • 29:21 – Eating Habits & Rhythm • 29:55 – Advanced Biohacking • 31:23 – Oxygen Therapy & Carbogen • 35:16 – Peptides & Longevity • 45:59 – Prayer, Gratitude & Performance • 51:03 – Reflections on Life & Mortality See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What’s keeping you stuck in a scarcity mindset instead of stepping into abundance? What truly sets successful people apart from those who struggle? Tony Robbins has spent decades answering these questions—coaching billionaires, world leaders, elite athletes, and everyday people to master their money, mindset, and mission. In this all-time classic podcast, he shares the hard-hitting truths about financial freedom, why fear is your biggest enemy, and how to break free from the psychological traps that keep you stuck. Tony and Dave dive deep into the wealth-building playbook that the world’s top investors use (including Warren Buffett, Ray Dalio, and Paul Tudor Jones), plus the biohacks and routines that fuel Tony’s legendary stamina. From the real secret to compounding wealth to stem cell breakthroughs that could change human longevity, this episode will shift the way you think about money, health, and success. Most people dream of financial freedom, but few actually achieve it. What’s holding you back—and how can you break through? What You’ll Learn: • The biggest mistake people make with money (and how to avoid it) • The mindset of the ultra-wealthy—how top investors think differently • Why fear is your greatest enemy in investing and personal success • The three essential money buckets—security, growth, and dreams • Tony’s top biohacks for insane energy and peak performance • The real secret to happiness and fulfillment (it’s not what you think) Resources:  • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Tony’s Website: https://www.tonyrobbins.com/ • Tony’s Instagram: https://www.instagram.com/tonyrobbins/?hl=en • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com SPONSORS:  -Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide.  -fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Timestamps: • 00:00 Intro • 00:50 Meet Tony Robbins • 02:18 Financial Wisdom & Motivation • 05:43 Psychology of Wealth • 10:10 Investment Strategies • 15:24 Balancing Money & Experiences • 21:21 Power of Giving • 30:06 Paying for College • 31:00 Commitment & Success • 31:53 Energy & Biohacks • 35:12 Cryotherapy & Inflammation • 38:54 Stem Cells & Regeneration • 41:59 Financial Freedom • 46:35 Wnt Pathway Breakthroughs • 52:35 Health & Longevity • 56:34 Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

From chart-topping hits to life-threatening lows—how did Timbaland go from producing for Jay-Z, Beyoncé, and Justin Timberlake to battling addiction and obesity? And more importantly, how did he take his life back? In this raw and revealing conversation, music icon Timbaland shares the blueprint behind his incredible transformation—how he broke free from opioid addiction, lost 130 pounds, and rewired his mindset for long-term success. He and Dave dive into the power of discipline, the dangers of quick fixes, and the hard truths about personal transformation. Timbaland opens up about the mental shift that saved his life, how he kicked a high-dose opioid habit cold turkey, and why his new “drug” of choice is something anyone can access. Most people want change, but few actually achieve it. What separates those who succeed from those who stay stuck? And how can you apply Timbaland’s hard-earned lessons to your own life? What You’ll Learn: • The #1 mindset shift that made weight loss & addiction recovery possible • Why self-discipline beats willpower—and how to build it like a muscle • The real reason most diets fail—and what actually works • The truth about opioid addiction and recovery—why most people never escape • How your daily habits shape your future—and how to change them fast • The shocking link between addiction, metabolism & long-term health • How Timbaland stayed clean without rehab—and why relapse wasn’t an option We’d like to extend our gratitude to Eudēmonia for providing the opportunity to record with Timbaland at their event. Eudēmonia, created by the founders of Wanderlust Festival, is a premier health and well-being summit. You can learn more about their initiatives and upcoming events here: https://wanderlust.com/ Resources:  • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Timbaland’s Website: https://www.timbaland.com/ • Timbaland’s Instagram : https://www.instagram.com/timbaland/?hl=en • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com SPONSORS:  -STEMREGEN | | Head to https://www.stemregen.co/dave for 20% off your first order.  -Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off. Timestamps: • 00:00 Trailer • 00:00 Introduction to the Human Upgrade • 00:09 Timbaland on Passion and Energy • 00:42 Balancing Passion and Avoiding Burnout • 02:04 Dreams and Manifestations • 04:51 Overcoming Addiction • 05:59 The Role of God in Recovery • 09:28 Helping Others with Addiction • 14:00 Weight Loss and Health Transformation • 16:29 Trusting Your Body’s Signals • 18:45 Skepticism About Modern Products • 21:10 Exploring Longevity and Individual Health • 22:23 The Intersection of Music and Spirituality • 25:56 Understanding Synesthesia and Its Impact • 27:41 The Journey to Weight Loss and Fitness • 35:08 The Importance of Sleep and Health • 37:23 Final Thoughts and Reflections See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Could the right form of a single vitamin be the difference between thriving and barely surviving? In this Part 2 conversation, human biologist and longevity expert Gary Brecka reveals the #1 overlooked factor that’s wrecking your health: methylation—your body’s ability to convert nutrients into fuel. If this process fails, your hormones, energy, and even mental health take a nosedive. Gary and Dave dive deep into the real cause of anxiety, ADHD, and mood disorders, the hidden genetic reason why diets fail, and why Big Pharma isn’t talking about this critical health breakthrough. Are you unknowingly setting yourself up for disease? What’s the simple fix that can reverse anxiety, gut problems, and even prevent genetic disease? And why is your doctor ignoring one of the biggest markers of longevity? What You’ll Learn: • The MTHFR gene mutation—and why it’s quietly affecting millions • Anxiety, ADHD, and depression—why these disorders start in your cells, not your brain • The gut-brain connection—how your microbiome controls your mood • Why your “healthy diet” might be hurting you (and what to eat instead) • How nutrient deficiencies are passed from mother to child—and how to stop it • The truth about homocysteine—the blood marker that could predict your lifespan • Why most people are living at 50% capacity—and how to get your energy back Resources:  • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Gary Brecka’s Website: https://bit.ly/4hlfyti • Gary Brecka’s YouTube: https://bit.ly/3E3Aaba • Gary Brecka’s Instagram: https://bit.ly/3PNsgFe • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com • The Mold Movie!: https://moldymovie.com/ SPONSORS:  -BON CHARGE | Go to https://boncharge.com/ and use coupon code DAVE to save 15%.  -Qualia | Go to https://www.qualialife.com/dave15 to get an additional 15% off subscriptions. Timestamps:  • 00:00 Trailer  • 00:31 What Is Methylation?  • 01:37 MTHFR, Folate & Your Health  • 04:17 How Methylation Affects Disease  • 06:41 Nutrient Deficiencies & Health Risks  • 07:09 Why Blood Work Matters  • 11:44 Homocysteine & Heart Health  • 21:37 Catecholamines & Anxiety  • 34:28 The Link Between Nutrients & Mood  • 34:48 How Catecholamine Ratios Affect Mental Health  • 35:39 Personal Health Struggles & Lessons  • 36:25 The Role of Methylation in Wellness  • 37:57 Methylation & Relationship Dynamics  • 39:49 Hidden Dangers of Mold Toxicity  • 52:55 Hydrogen Water for Health  • 01:01:19 Mitochondria’s Role in Longevity  • 01:02:23 Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Why were our grandparents stronger, healthier, and living longer—without the “advancements” of modern medicine? Gary Brecka, one of the world’s leading experts in human longevity and performance, exposes the hidden crisis that’s wrecking your hormones, slashing your energy, and cutting your lifespan short. In this no-holds-barred conversation with Dave Asprey, they break down the corporate greed, medical corruption, and environmental toxins designed to keep you sick, weak, and dependent. What’s really causing the testosterone collapse in men and women? How is AI changing the game for hormone optimization, biohacking, and personalized health? And why are we aging faster than ever—while Big Pharma profits? This first episode in a two-part series is a deep dive into hormone optimization, testosterone, cholesterol myths, longevity hacks, and the AI-driven future of health.  What You’ll Learn: • Why testosterone levels are plummeting—and how to restore them naturally • The real reason life expectancy is dropping (hint: it’s not just diet) • The Kellogg conspiracy—how food was designed to lower libido & testosterone • Why mainstream medicine is failing you (and what to do instead) • How AI and big data are rewriting the rules of health & longevity in• The shocking truth about cholesterol, heart disease, and pharmaceuticals • Why functional medicine & biohacking hold the key to real health optimization Resources:  • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Gary Brecka’s Website: https://bit.ly/4hlfyti • Gary Brecka’s YouTube: https://bit.ly/3E3Aaba • Gary Brecka’s Instagram: https://bit.ly/3PNsgFe • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com SPONSORS:  Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.  Apollo Neuro | To get an Apollo wearable, go to https://apolloneuro.com/Dave and save 15%. Timestamps: • 00:00 – Trailer • 00:42 – Introduction to The Human Upgrade • 01:35 – Meet Gary Brecka • 03:32 – Performance vs. Longevity • 06:16 – The Importance of Testosterone • 15:11 – Historical Hormone Levels • 18:00 – Population Averages in Health • 18:51 – The Flaws of Grading on a Curve • 20:35 – Corporate Influence on Health • 21:04 – The Danger of Cumulative Dosage • 22:20 – Social Media & Public Perception • 25:19 – Independent Research Matters • 32:21 – Big Data & AI in Health • 36:02 – The Future of Personalized Medicine • 36:49 – Conclusion & Teaser for Part Two See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Billy Carson, a Harvard-certified expert in ancient civilizations and an MIT-trained scholar in neuroscience, has spent decades decoding the mysteries of lost technology, quantum reality, and human optimization. Alongside Elisabeth Carson, a biohacker and neuroscience researcher, they bridge the gap between ancient wisdom and modern science—revealing secrets that could transform your mind, body, and reality. What if the Great Pyramid wasn’t just a monument but a powerful energy device designed to amplify human potential? What if ancient civilizations understood frequency, grounding, and longevity in ways modern science is only beginning to grasp? In this episode, the Carsons connect the dots between lost technology, bioenergetics, and conscious relationships, showing how these ancient systems align with the latest research on vibrational healing, mitochondrial energy, and peak performance. They explore how quantum fields influence cellular regeneration, why high-frequency living affects health and relationships, and how suppressed knowledge could redefine the future of wellness. What You’ll Learn: • How the Great Pyramid functioned as an energy generator—and how to apply its principles to longevity • The forgotten science of frequency and its effects on health, aging, and vitality • How quantum energy and grounding can optimize mitochondrial function • The connection between biohacking, consciousness, and relationships • Why suppressed ancient knowledge holds the key to true human potential Resources:  • 2025 Biohacking Conference: https://biohackingconference.com/2025 • 4biddenknowledge YouTube – https://www.youtube.com/@ForbiddenKnowledge1 • 4biddenknowledge Website – https://www.4biddenknowledge.com/ • Billy Carson Instagram – https://www.instagram.com/4biddenknowledge/?hl=en • Elisabeth Carson Instagram - https://www.instagram.com/elisabethicarson/?hl=en • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Book – Smarter Not Harder: https://daveasprey.com/books • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com SPONSORS:  Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Timestamps: • 00:00 Trailer • 00:39 Meet Dave Asprey • 02:16 Trauma, Success & Relationships • 04:22 Billy & Elizabeth Carson on Growth • 10:09 Birth & Pre-Natal Trauma • 19:30 Healing & Biohacking • 23:16 Relationships & Triggers • 28:35 Vitamin D & Nutrients • 35:25 Empathy & Intuition • 37:24 Manifestation • 41:25 Neuroscience & Altered States • 53:04 Ancient Wisdom & Biohacking • 57:45 Ancient Technologies • 01:08:26 Giants & Six Fingers • 01:08:58 Sumerian Artifacts • 01:10:28 Hidden Agendas • 01:13:32 Hypnosis Revelations • 01:19:21 Power of Intuition • 01:30:11 Love & Self-Discovery • 01:35:52 Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Everything you’ve been told about weight loss is a lie!In this episode, Dr. Nick Norwitz, a metabolic health expert with accolades from Oxford and Harvard, joins Dave to expose the biggest myth in dieting: Calorie Counting. Together, they dismantle outdated weight-loss advice and reveal the truth about metabolism that could revolutionize your health. Dr. Norwitz shares cutting-edge science and personal stories that challenge the “eat less, move more” narrative, uncovering why traditional dieting often fails—and what actually works. From the role of ketosis in healing chronic illness to the surprising ways fasting affects hair loss, metabolism, and inflammation, this episode is packed with actionable insights that you won’t hear anywhere else. You’ll also learn how viruses might be fueling food addiction, why gut health is the missing key to metabolic recovery, and how new research could unlock the future of personalized medicine. If you’ve ever felt like your metabolism was holding you back, this conversation will give you the tools to take control of your health for good. What You’ll Learn:  • Why calorie counting is useless—and the better way to lose weight  • The shocking truth about how your metabolism ACTUALLY works  • How ketosis and fasting can heal inflammation and chronic disease  • The role of gut health and microbiome diversity in weight loss  • New research on food addiction and its surprising link to viruses  • Why individualization is the key to sustainable health Resources:  • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Nick Norwitz’s YouTube – https://www.youtube.com/@nicknorwitzPhD • Nick Norwitz’s Website – https://www.nicknorwitz.com/ • Follow Nick on Instagram – https://www.instagram.com/nicknorwitz/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Book – Smarter Not Harder: https://daveasprey.com/books • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com SPONSORS:  Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Timestamps: • 00:00 Trailer • 00:39 Meet Dr. Nick • 04:44 Nick’s Health Journey • 07:54 Keto Diets • 09:37 Modern Medicine Challenges • 13:31 Exercise vs. Diet • 14:32 Obesity Memory • 17:36 Keto Cycling • 20:51 Microbiome Health • 26:26 Fasting & Hair Loss • 34:56 Alzheimer’s Insights • 45:11 Cold Plunge Benefits • 45:43 Dopamine Boosts • 46:26 Cold Plunge & Inflammation • 47:15 Best Time to Cold Plunge • 48:18 Pain & Dopamine • 49:31 Exercise & Stress • 51:49 Cholesterol & Inflammation • 01:05:42 Debunking Calories In/Out • 01:07:09 Food Addiction • 01:11:15 Metabolic Health Tips • 01:24:13 Nick’s Mission See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if the key to living longer isn’t avoiding stress—but mastering it Jeff Krasno, founder of Commune and renowned stress expert, joins Dave to reveal why most of us have stress all wrong. In this fascinating conversation, Jeff redefines how we think about stress—showing how it can be your greatest ally instead of your worst enemy. From his groundbreaking new book Good Stress to the ancient practices that have stood the test of time, Jeff shares how to unlock the hidden potential of stress to build resilience, foster connections, and boost longevity. You’ll discover why crying is an emotional biohack, how to spot the fine line between good and bad stress, and why the modern world keeps us stuck in a chronic stress loop—and how to break free. Jeff also dives into the science of emotional regulation, the role of connection in health, and the radical power of embracing discomfort to create balance and ease in your life. What You’ll Learn:  • How to turn stress into a tool for resilience and longevity  • Why Jeff calls chronic ease the root of modern disease  • The science of tears: how crying regulates stress and boosts health  • How you can build a “psychological immune system” for emotional regulation  • The key to balancing good stress and avoiding burnout  • Why discomfort is the path to growth—and how to embrace it Resources:  • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Jeff Krasno’s Website – https://www.jeffkrasno.com/ • Preorder Good Stress – https://www.onecommune.com/goodstressbook#preorder • Follow Jeff on Instagram – https://www.instagram.com/jeffkrasno • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Book – Smarter Not Harder: https://daveasprey.com/books • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com SPONSORS:  Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide. Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. Timestamps: • 00:00 – Intro • 01:02 – Meet Jeff Krasno • 02:16 – Topanga Fires Survival • 04:14 – Good Stress vs. Bad Stress • 06:14 – Cortisol’s Role in Stress • 13:13 – Social Media Triggers • 20:32 – Stressful Conversations • 31:34 – Cold Therapy Benefits • 42:26 – Stress and Recovery Balance • 45:58 – High Altitude Training • 47:29 – Cold Therapy Fails • 49:42 – Science of Crying • 54:51 – Reflections on Legacy • 59:37 – Balancing Stress and Ease • 01:10:30 – Nature and Spirituality • 01:22:52 – Facing Death with Grace • 01:32:53 – Closing Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if you could cheat aging, indulge in life’s guilty pleasures, and still thrive? Dr. Sandra Kaufmann, a pioneering longevity expert and fearless explorer of the biochemical frontier, joins Dave to reveal how you can bend the rules of biology to live longer, smarter, and stronger. Forget perfection—Dr. Kaufmann’s radically practical approach embraces the human side of longevity, showing you how to optimize your body while enjoying the ride. From downing Diet Cokes to defying traditional medical dogma, she’s rewritten the playbook on anti-aging with her Seven Tenets of Aging. Together, she and Dave dive into everything from molecular hacks for outsmarting junk food to unlocking the secret power of your mitochondria, DNA, and circadian rhythms. This episode goes beyond the surface with mind-blowing insights, hilarious moments, and actionable steps to take your health (and your fun) to the next level. What You’ll Learn: • The Seven Tenets of Aging and how they’ll change your approach to health • Why indulging in “bad” habits doesn’t have to sabotage your longevity • Biochemical secrets to combat oxidative stress, glycation, and cellular junk • The real story behind NAD, circadian rhythms, and the tools for better sleep • How to create a personalized health plan that’s sustainable, effective—and fun Resources:  • Supplement Protocol One-Sheet for this episode: https://www.instagram.com/dave.asprey/?hl=en• 2025 Biohacking Conference: https://biohackingconference.com/2025 • Kaufmann Protocol Website: https://kaufmannprotocol.com • Sandra Kaufmann’s Book – Why We Age and How to Stop It: https://www.amazon.com/Kaufmann-Protocol-Why-Age-Stop/dp/0692089047 • Sandra Kaufmann’s Instagram: https://www.instagram.com/kaufmannantiaging/?hl=en • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Book – Smarter Not Harder: https://daveasprey.com/books • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com  SPONSORS:  Leela Quantum | Head to https://leelaq.com/DAVE for 10% off. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Timestamps: • 00:00 Trailer • 00:45 Guest Introduction • 02:30 Longevity Insights • 04:22 Personal Stories • 08:00 Pharmaceuticals • 12:26 Diet and Lifestyle • 18:19 Seven Tenets • 22:04 Sleep and Circadian Rhythms • 26:41 NAD and Supplements • 37:46 Blood Sugar and AGEs • 47:09 Microcirculation • 49:08 NRS and Imports • 49:18 Celebrex Medication • 50:03 Celebrex Benefits • 50:41 Alzheimer’s and Celebrex • 51:28 Antioxidants • 54:26 Stem Cells and Exosomes • 58:03 Laser Skin Treatments • 01:07:34 Hormones and Longevity • 01:20:03 Lithium for Mood • 01:27:45 Gender and Longevity • 01:32:39 Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Is there actual “magic” on this planet, or is it just in the movies? Dr. Barry Morguelan, a top surgeon and one of only nine living grandmasters of an ancient Lao Tzu lineage, joins Dave to share secrets that have been hidden for 5,000 years. Together, they explore how the principles behind quantum physics, energy mastery, and timeless healing techniques can revolutionize your health, mindset, and life. From breaking rocks with energy to healing broken bones with focused intent, Dr. Barry reveals the extraordinary power of the “Great 8” — a framework to unlock your potential in relationships, creativity, health, intelligence, and more. This episode is packed with incredible stories, actionable wisdom, and a secret GIFT to help you start your own journey toward unparalleled vitality and longevity! What You’ll Learn: • The 8 ancient secrets to mastering energy, healing, and peak performance • How you can harness quantum physics for success • Why energy techniques can REVERSE aging and boost health naturally • The science of serendipity and how you can harness it daily • How to grow stronger, smarter, and healthier every day with simple practices Resources:  • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Follow Dr. Barry on Instagram: https://www.instagram.com/energyforsuccess.official?igsh=eGcwZWhid3Q1M2Rm&utm_source=qr• Explore the Great 8 and Get Your Free Gift: https://energyforsuccess.com/dave/ • Learn More About Energy Practices: https://energyforsuccess.com/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Book – Smarter Not Harder: https://daveasprey.com/books • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com  SPONSORS:  - Lumiram | Go to http://healthlighting.com/dave to save 10% on your order. - Calroy | Head to https://calroy.com/dave for an exclusive discount. Timestamps: • 00:00 Trailer • 01:10 Introduction to Dr. Barry and His Journey • 06:16 The Turning Point: Mrs. Rodriguez’s Story • 09:04 Exploring Alternative Medicine Around the World • 13:02 Discovering Ancient Chinese Healing Techniques • 16:39 The Power of Quantum Physics and Lao Tzu’s Teachings • 27:25 Personal Experiences with Energy Healing • 36:35 The Great Eight: Structuring Your Day for Success • 36:51 Introduction to Energy for Success • 37:17 Understanding the Great Eight • 38:23 The Matrix and Animal Brain • 44:39 The Importance of Serendipity • 49:35 Four Categories of People • 53:02 Personal Experiences and Lessons • 58:34 The Power of Energy Practices • 01:07:06 Conclusion and Call to Action See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What happens when nearly 60 years of combined biohacking expertise collide in one podcast? Peter Diamandis is a world-renowned futurist, space entrepreneur, and innovator behind groundbreaking ventures like the XPRIZE and Abundance 360. Dave sits down with Peter to combine their nearly 60 years of biohacking expertise, delivering the ultimate playbook for living longer and healthier.They dive into revolutionary AI-driven health solutions, mindset shifts that fuel vitality, and practical routines you can start today. Peter, the author of The Longevity Guidebook, shares deeply meaningful tools and tips to expand your healthspan for decades to come. What You’ll Learn:  • The top AI tools reshaping health and longevity  • Simple daily habits that improve energy, sleep, and brain performance  • Why mindset is the key to adding years to your life  • The cutting-edge science of age reversal and functional health  • How Peter and Dave biohack their routines for peak performance Resources:   • 2025 Biohacking Conference: https://biohackingconference.com/2025  • Peter Diamandis’s New Book: https://longevityguidebook.com/home-blk-nav  • Peter Diamandis’s Website: https://www.diamandis.com/  • Peter Diamandis’s Purpose Finder (MTP): https://purposefinder.ai/  • Danger Coffee: https://dangercoffee.com  • Dave Asprey’s Website: https://daveasprey.com  • Dave Asprey’s Book – Smarter Not Harder: https://daveasprey.com/books  • Dave Asprey’s Linktree: https://linktr.ee/daveasprey  • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com  • Own an Upgrade Labs: https://ownanupgradelabs.com  • Upgrade Labs: https://upgradelabs.com  • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com SPONSORS:  -Omni-Biotic | Visit omnibioticlife.com/dave and use code DAVE20 for 20% off. -LMNT | Free LMNT Sample Pack with any drink mix purchase by going to drinklmnt.com/dave. Timestamps:  • 00:00 Open  • 00:53 Introduction to Peter Diamandis  • 01:54 Peter’s Longevity Journey  • 03:26 Tracking Sleep and Biohacking  • 05:49 The Importance of Deep Sleep  • 07:22 Thinking Big and Longevity  • 10:36 Russian Innovations in Sleep  • 25:29 AI and Longevity  • 29:01 Gene Editing and Epigenetics  • 35:13 Light Therapy and Routines  • 43:07 Gut Health and Endotoxins  • 44:17 Exploring Conscious Pain Practices  • 45:51 Hacking Hot Tubs for Health Benefits  • 46:28 The Science Behind Dopamine Reset  • 46:43 Introduction to Fountain Life  • 48:41 Advanced Diagnostics and AI Integration  • 50:29 Therapeutics and Cutting-Edge Treatments  • 51:41 The Evolution of Longevity Companies  • 55:30 The Future of Longevity and Healthspan  • 01:01:27 The Role of AI in Health and Longevity  • 01:07:31 Personal Longevity Practices and Insights  • 01:16:43 Finding Your Purpose for Longevity  • 01:24:01 Final Thoughts and Resources See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if you could ditch your glasses forever by simply doing a 10-minute exercise each day? In this episode, Dave sits down with Dr. Bryce Appelbaum, a visionary in vision biohacking, to uncover how simple techniques can transform your eyesight. From near-far focusing to eye stretches, these exercises don’t just improve your vision—they enhance your brain’s performance, energy, and overall health. Dr. Bryce shares his own journey of overcoming severe vision challenges, the science behind vision training, and how anyone can rewire their brain for sharper sight. If you’re dealing with nearsightedness, eye strain, or just want to keep your eyes sharp as you age, this episode shares simple ways to improve how you see the world—literally! What You’ll Learn: • Why vision training is the next frontier in biohacking • Three free techniques to improve your vision naturally • How your eyesight affects brain performance and energy levels • Why kids and adults need to get outside for better eye health • How to train your eyes to stop relying on glasses Go to www.screenfit.com/enroll and use code DAVE ($200 OFF with the code) Or Visit myvisionfirst.com/dave/ for 5000$ off the premium concierge program! SponsorsZbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.Resources:  • 2025 Biohacking Conference – https://biohackingconference.com/2025 • Screenfit- Visit https://www.screenfit.com/enroll and use code DAVE ($200 OFF with the code, from $497 to $297) • MyVisionFirst – Visit https://myvisionfirst.com/dave/ and apply now to get $5000 off • Danger Coffee – https://dangercoffee.com • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Timestamps: • 00:00 Intro • 00:29 Dave Asprey’s Vision Journey • 04:33 Understanding Vision Beyond 20/20 • 08:01 Impact of Environment on Vision • 22:47 Exercises to Improve Vision • 27:29 Effective Eye Exercises for Better Vision • 27:46 Daily Routine for Eye Health • 29:12 Peripheral Vision Training • 31:15 Vision and Body Connection • 33:38 Handling Visual Overload • 35:04 Vision Training Benefits • 39:25 Neuroplasticity and Vision • 45:22 Vision Training for All Ages • 46:38 Practical Vision Improvement Tips • 54:24 Final Thoughts on Vision Training See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if the secret to living to 250 was simply sitting in the garden? In this episode, Dave sits down with Christian Drapeau, a leading expert in stem cell science, to explore the plants and natural practices that could unlock extreme longevity. From goji berries to reishi mushrooms, these age-old remedies do more than nourish—they activate your body’s innate repair system, boosting stem cells and accelerating healing. Christian dives into the fascinating stories behind these plants, their ancient origins, and how modern science is proving their power to extend life. He also shares how anyone—regardless of age—can tap into these natural tools to transform their health and longevity. Imagine harnessing the same methods as a Chinese healer reportedly living to 250 years old. Could these practices be the missing link to longer, healthier lives? What You’ll Learn: • The surprising plants that naturally stimulate stem cells • How stem cells repair and rejuvenate your body from the inside out • Why fasting can reset your cellular health • Practical tips to harness your body’s natural ability to heal • The secrets to improving recovery, energy, and longevity Resources:  • 2025 Biohacking Conference - STEMREGEN is the Title Sponsor – https://biohackingconference.com/2025 • STEMREGEN Website - Visit stemregen.co/dave and save 20% on STEMREGEN! • Christian Drapeau’s Website - https://christiandrapeau.com  • Danger Coffee – https://dangercoffee.com • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors: Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.  Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide. Timestamps: • 00:00 Intro • 00:57 Meet Christian Drapeau: Stem Cell Expert • 02:22 Understanding the Innate Repair System • 04:26 Stem Cells and Aging: The Science Explained • 05:27 Fasting and Stem Cell Rejuvenation • 08:34 STEMREGEN: Activating Your Body’s Stem Cells • 12:09 Historical Longevity Practices • 17:59 Enhancing Stem Cell Function: Lifestyle Tips • 22:45 The Role of PEMF in Stem Cell Activation • 26:45 The Importance of Immediate Recovery • 27:22 Stem Cells and Longevity • 28:13 The Bank Account Analogy of Aging • 29:05 Stem Cells and Age-Related Diseases • 30:42 Mind Over Matter: The Brain’s Role in Stem Cell Release • 32:51 The Quantum Mechanics of Stem Cells • 36:22 The Role of Science in Understanding Reality • 42:24 Biological Clocks and Stem Cells • 46:08 Future of Stem Cell Research and Applications • 49:36 Practical Applications and Success Stories • 52:23 Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Are we protecting our kids—or unknowingly putting their health at risk? Dr. Joel “Gator” Warsh isn’t just another pediatrician; he’s a bold voice speaking out on the vaccine debate that’s dividing parents, doctors, and society. In this episode, we pull back the curtain on one of the most censored and controversial topics of our time. With his integrative and functional approach, Dr. Warsh unpacks the startling rise in chronic illnesses among children and questions if we’re truly asking the hard questions about vaccine safety and efficacy. This isn’t about taking sides—it’s about uncovering the truths every parent needs to know. Dave and Dr. Warsh dive deep into the science, the myths, and the hidden risks Big Pharma doesn’t want you to hear about. Whether you’re a parent, a skeptic, or just someone seeking the truth, this episode will give you the tools and insights to navigate this complex issue with confidence. What You’ll Learn:  • The alarming rise in chronic illnesses and what might be driving it  • Why vaccine safety studies may not tell the whole story  • The critical questions every parent should ask before vaccinating  • How toxins in our environment are impacting our kids’ health  • Practical steps to protect your children in today’s world  Resources:   • 2025 Biohacking Conference – https://biohackingconference.com/2025  • Dr. Joel “Gator” Warsh’s Book: Parenting at Your Child’s Pace – https://www.amazon.com/Parenting-Your-Childs-Pace-Pediatricians/dp/1454952490  • Dr. Joel “Gator” Warsh’s Website – https://www.integrativepediatrics.com  • Dr. Joel “Gator” Warsh on Instagram – https://www.instagram.com/drjoelgator  • Danger Coffee – https://dangercoffee.com  • Dave Asprey’s Website – https://daveasprey.com  • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books  • Dave Asprey’s Linktree – https://linktr.ee/daveasprey  • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com  • Own an Upgrade Labs – https://ownanupgradelabs.com  • Upgrade Labs – https://upgradelabs.com  • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors: -STEMREGEN | Head to https://www.stemregen.co/dave for 20% off your first order. -BON CHARGE | Go to https://boncharge.com/ and use coupon code DAVE to save 15%.  Timestamps:  • 00:00 Intro  • 00:40 Personal Health Journey and Pediatric Concerns  • 01:41 Interview with Dr. Joel Gator Warsh  • 02:49 Rising Chronic Diseases in Children  • 04:03 Factors Contributing to Health Issues  • 10:13 Debating Vaccine Safety and Efficacy  • 30:32 Historical Context and Vaccine Research  • 44:18 Introduction to Dr. Joe Dispenza and Meditation  • 45:13 Genetics and Vaccine Controversies  • 46:16 The Importance of Individualized Medicine  • 49:02 Western Medicine’s Flaws and Alternatives  • 50:07 Childhood Health Crisis and Solutions  • 50:52 Pharmaceutical Industry Critique  • 52:09 The Role of Parents and Doctors in Child Health  • 01:04:43 The Influence of Big Pharma on Medicine  • 01:19:56 Balancing Vaccination Decisions  • 01:25:44 Conclusion and Final Thoughts  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Your hearing isn’t just about sound—it’s the key to sharper focus, deeper connections, and increased awareness. In this episode, Dave explores the cutting-edge world of hearing technology with Brandon Sawalich, CEO of Starkey, and reveals how you can gain superhuman hearing with almost no effort.“Listening” to this episode is going to be one of the best things for your hearing. But why? Because your hearing isn’t just about detecting sounds—it’s about transforming the way you experience the world. Imagine real-time translation in 75 languages, tuning out noise pollution, and amplifying what truly matters—all while protecting your brain from cognitive decline and boosting your overall performance.Brandon shares the groundbreaking innovations that redefine what hearing devices can do. From biohacking your auditory environment to integrating AI for mood and health tracking, this conversation will change how you think about your ears, your brain, and your future.What You’ll Gain from This Episode: • Discover how superhuman hearing enhances focus and reduces mental fatigue • Learn why better hearing can slow brain aging and improve mental health • Get an inside look at AI-powered hearing technology that’s changing lives • Understand the surprising connection between hearing and peak performance • Find out how upgrading your hearing can unlock new opportunities for successSponsor: -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.-ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources: • Starkey Hearing Technologies – Explore AI-powered hearing aids and innovations: https://www.starkey.com • Starkey Blog – Stay updated on the latest in hearing health: https://www.starkey.com/blog •   Starkey Instagram - https://www.instagram.com/starkeyhearing/ • Danger Coffee – Clean, mold-free coffee for sustained energy: https://dangercoffee.com • Dave Asprey’s Website – Explore biohacking tools, books, and more: https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – Biohacking made simple: https://daveasprey.com/books • Dave Asprey’s Linktree – Access all Dave’s platforms: https://linktr.ee/daveasprey • Upgrade Collective – Join live podcast recordings: https://www.ourupgradecollective.com • Own an Upgrade Labs – Franchise opportunities for cutting-edge health labs: https://ownanupgradelabs.com • Upgrade Labs – The ultimate biohacking experience: https://upgradelabs.com • 40 Years of Zen – Neurofeedback for advanced cognitive enhancement: https://40yearsofzen.comTimestamps: • 00:00 Introduction to Hearing Loss • 01:23 Dave Asprey’s Personal Hearing Journey • 02:47 Guest Introduction: Brandon Sawalich • 03:45 Advancements in Hearing Technology • 06:47 The Importance of Hearing for Brain Health • 17:32 Hearing Aids as Performance Enhancers • 25:32 Future Innovations in Hearing Technology • 27:03 Detecting Lies with Technology • 27:26 The Science of Sleep Enhancement • 29:57 Innovation and Risk-Taking in Business • 32:18 Addressing EMF Concerns with Hearing Aids • 34:26 Ethical Considerations in Technology • 37:06 Empowering Users with AI and Hearing Technology • 43:38 Future of Biohacking and Hearing Superpowers • 44:57 Conclusion and Final ThoughtsSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Fear is quietly running your life—and it’s holding you back from the purpose and success you deserve. In this episode, we revisit Dave chatting with one of the keynote speakers for the Biohacking Conference 2025, Ryan Holiday, the bestselling author of Courage Is Calling, to tackle the one thing standing between you and your potential: fear. Why should you listen? Because fear is the root cause of procrastination, self-doubt, and the endless excuses that keep you stuck. Ryan reveals why courage isn’t just about bravery—it’s about making the hard choices that align with your purpose, even when the stakes are high. Drawing on powerful examples from history and modern life, Ryan explains how fear can be transformed into a catalyst for action and why embracing discomfort is the key to unlocking true freedom. If you’ve ever felt paralyzed by uncertainty, this episode will give you the tools and perspective to take control, face your fears, and create the life you’re meant to live. Why This Episode Matters:  • You’ll discover how fear sneaks into your decisions—and how to stop it  • Learn why courage is the ultimate skill for success and fulfillment  • Get actionable advice to break through self-imposed limits  • Understand the psychology of fear and how to use it as fuel  • Hear real-life stories of people who overcame fear to achieve greatness Resources:  2025 Biohacking Conference – https://biohackingconference.com/2025 Ryan Holiday’s Website – https://ryanholiday.net Daily Stoic Website – https://dailystoic.com/ Ryan Holiday’s Book: Courage Is Calling – https://a.co/d/czEfCXC Ryan Holiday’s Instagram – https://www.instagram.com/ryanholiday Danger Coffee – https://dangercoffee.com Dave Asprey’s Website – https://daveasprey.com Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey’s Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. -Pendulum | Go to https://pendulumlife.com/ and use code Asprey20 for your first month of GLP-1 or any Pendulum formula. Timestamps:  • 00:00 – Intro  • 00:44 – Discussing Ryan Holiday’s Work  • 02:37 – The Concept of Courage  • 08:09 – Fear and Courage in History  • 12:41 – Stoic Philosophy and Modern Applications  • 21:50 – The Four Virtues and Their Interrelation  • 28:39 – Challenges in Admitting Mistakes  • 35:21 – Navigating Business Risks During a Pandemic  • 36:44 – The Essence of Courage in Business and Life  • 37:03 – Reed Hastings and the Duality of Courage  • 40:06 – Moral Courage: Lessons from History  • 43:35 – The Debate on Mandates and Personal Freedom  • 45:22 – Balancing Public Health and Individual Rights  • 58:29 – The Role of Responsibility in Society  • 01:09:01 – The Importance of Intellectual Courage  • 01:12:04 – Reaching Audiences in a Noisy World  • 01:13:27 – Final Thoughts and Encouragement See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today we are bringing back one of our all-time favorite episodes with James Altucher. Dave sits down with James, an entrepreneur, bestselling author, and master experimenter, to uncover why the 10,000-hour rule might just be holding you back. Instead of grinding your way to expertise, James reveals his 10,000 Experiment Rule—a game-changing approach to mastering any skill faster than you thought possible. From comedy stages to boardrooms, James has redefined success through relentless experimentation and bold pivots. In this electrifying conversation, he exposes the toxic allure of “failure porn” and why glorifying failure might be sabotaging your growth. You’ll learn why skipping the line isn’t just possible—it’s essential for thriving in a world obsessed with rigid rules. This episode dives deep into the power of curiosity, the art of experimentation, and the strategies James uses to crush the myth of conventional wisdom. Whether you’re stuck in a career rut, looking to start something new, or just want to optimize your life, James delivers unfiltered insights to help you rewrite the rules. What You’ll Learn: • Why the 10,000-hour rule is outdated—and what actually works • How “failure porn” is dragging you down (and how to escape it) • The 10,000 Experiment Rule that accelerates skill mastery • Bold strategies to break through limits and skip the line in any industry • Why curiosity is the ultimate superpower for growth and success • Practical steps to monetize your passion and build a life you love Resources:  2025 Biohacking Conference – https://biohackingconference.com/2025 James Altucher’s Website – https://www.jamesaltucher.com The James Altucher Show Podcast – https://podcasts.apple.com/us/podcast/the-james-altucher-show/id794030859 Danger Coffee – https://dangercoffee.com Dave Asprey’s Website – https://daveasprey.com Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey’s Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors -Calroy | Head to https://calroy.com/dave for an exclusive discount. -Viome | Go to https://viome.com/dave to save $110 on the Full Body Intelligence Test.  Timestamps: 00:00 Introduction to The Human Upgrade Podcast 00:38 Meet James Altucher: Entrepreneur and Author 01:02 The Comedy Journey: From Advice to Stage 02:06 The Controversial New York Article 03:42 Facing Backlash and Public Reaction 10:46 The 10,000 Experiment Rule 15:44 Skipping the Line: Challenging Conventional Wisdom 23:35 The Importance of Loving What You Do 31:30 A Chance Encounter with Howard Schultz 32:11 The Plus Minus Equals Technique 33:26 Applying Techniques to Chess Mastery 34:43 The Importance of Curiosity 36:30 Experimenting with Comedy 38:44 The Concept of Failure Porn 40:39 The Hero’s Journey in Business 44:42 Living an Experimental Life 47:10 Frame Control in High-Stakes Situations 53:43 Advice for Parents and Kids 55:29 Conclusion and Book Promotion See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Can you use hate to make the world a better place?  Daryl Davis, a world-class jazz musician, didn’t just confront hate—he dismantled it. By sitting down with over 200 Ku Klux Klan members, he inspired them to leave their robes behind. But this isn’t just a story about racism or redemption; it’s a story about the incredible power of human connection and the lessons it holds for all of us. In this special episode, Dave explores how Daryl turned impossible conversations into transformative breakthroughs. Together, they unpack the mindset shifts, emotional intelligence, and fearless curiosity that can break down barriers of all kinds—whether they’re rooted in bias, fear, or misunderstanding. Daryl’s approach to erasing hate is so unique, so impactful, that it may just change how you view conflict, compassion, and even your own health. What You’ll Learn:  • How Daryl’s global upbringing shaped his fearless approach to conflict  • Why eliminating hate starts with understanding, not opposition  • The neuroscience of compassion and how it rewires your brain  • How forgiveness can transform your health and happiness  • A step-by-step framework for tackling impossible conversations Resources:  2025 Biohacking Conference – https://biohackingconference.com/2025 Daryl Davis's Book: Klan-destine Relationships (Go read it for free at your local library instead of buying on Amazon :)) Daryl Davis's Website – https://www.daryldavis.com Daryl Davis on Instagram – https://www.instagram.com/realdaryldavis/ Danger Coffee – https://dangercoffee.com Dave Asprey’s Website – https://daveasprey.com Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey’s Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors: -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Timestamps:  • 00:00 A Shocking Parade Experience  • 00:38 Meeting the KKK: First Impressions  • 01:06 Introducing Daryl Davis  • 03:46 Daryl’s Unique Upbringing  • 09:52 Confronting Racism: A Lifelong Quest  • 14:16 The Power of Travel and Perspective  • 18:25 A High School Encounter with Nazis  • 21:12 Confronting the Klan Leader  • 30:57 Changing Minds: A Personal Approach  • 36:30 The Illusion of Latent Genes  • 42:08 Collecting Klan Robes: A Symbolic Victory  • 46:17 Facing the Klan: Staying Grounded  • 48:27 Challenging Beliefs: Confronting Hate  • 49:15 The Journey to Writing ‘Clandestine’  • 50:26 Introducing ‘The Klan Whisperer’  • 51:35 Reflections on Racism and History  • 57:29 The Power of Forgiveness  • 59:28 Freedom of Speech and Its Limits  • 01:02:21 Personal Stories of Racism  • 01:13:16 Cultural Understanding and Misunderstandings  • 01:25:16 The Impact of Music on Memory  • 01:29:02 Final Thoughts and Upcoming Events See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Is AI About to Replace Your Doctor? Or Save Your Life? The tools that are reshaping healthcare will redefine medicine—and your life—in ways you’ve never imagined. Will artificial intelligence and regenerative therapies like stem cells and exosomes make doctors obsolete? Or will they finally unlock the secrets to living to 180? In this episode, Dave sits down with Dr. Pradeep Albert, a leader in regenerative medicine and AI-driven imaging, to explore the intersection of technology, longevity, and healing.  Dr. Albert shares groundbreaking insights on how AI is revolutionizing medical diagnostics, replacing outdated systems, and empowering patients to take control of THEIR OWN health. He also dives deep into regenerative therapies—how PRP, exosomes, and stem cells are changing the game for injuries, inflammation, and aging.  Can AI improve patient-doctor relationships? Are doctors becoming coaches instead of gatekeepers? And most importantly, how can you leverage these tools to outlive your peers and enhance every aspect of your health? What You’ll Learn:  • Why 50% of people won’t make it past 76—and how to beat the odds  • How AI is already better than doctors at diagnosing certain conditions  • The truth about PRP, exosomes, and stem cells—and when to use each  • The three rules of longevity every person needs to know  • How your mindset and epigenetics can help you live longer and healthier Resources:  2025 Biohacking Conference – https://biohackingconference.com/2025 Dr. Pradeep Albert’s Book: Exosomes, PRP, and Stem Cells…Medicine – https://www.amazon.com/Exosomes-Stem-Cells-Musculoskeletal-Medicine/dp/B0C2S59S8K Dr. Pradeep Albert’s Book: Lifespan Decoded –https://lifespandecoded.com/ Dr Pradeep Albert’s Website – https://drpradeepalbert.com/ Danger Coffee – https://dangercoffee.com Dave Asprey’s Website – https://daveasprey.com Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey’s Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com  Sponsors: ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order.  OneSkin | Go to https://oneskin.co/ and use code ASPREY15 for 15% off your purchase. Timestamps:  • 00:00 – Introduction to AI in Medicine  • 00:36 – The Role of AI in Longevity  • 00:51 – Meet Dr. Pradeep Alpert  • 01:11 – AI’s Impact on Healthcare  • 02:07 – Changing Role of Doctors  • 05:01 – AI in Medical Imaging  • 06:37 – Orthopedics and AI  • 09:19 – Longevity and Epigenetics  • 14:16 – The Importance of Mindset  • 29:08 – Trust in the Medical System  • 43:18 – DIY Health and Longevity  • 44:21 – The Future of Insurance and Medical Costs  • 45:45 – Advancements in Imaging Technology  • 47:26 – The Art of Physical Examination  • 50:21 – Regenerative Medicine: PRP, Exosomes, and Stem Cells  • 01:00:23 – Challenges in the US Medical System  • 01:07:54 – The Role of AI in Medicine  • 01:18:14 – Final Thoughts and Book Promotion See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most people don’t think about their liver until it’s too late. In this episode, Dave sits down with Siggi Clavien, founder of de-liver-ance® & The Liver Clinic, to uncover the hidden superpowers of the body’s most underrated organ: the liver. This is a deep dive into why your liver is the ultimate game-changer for your energy, brain power, and longevity. Siggi reveals groundbreaking insights on reversing fatty liver disease, boosting detoxification, and harnessing the liver’s regenerative capabilities. From fighting brain fog to protecting against toxins, this episode will have you rethinking everything about how you treat your body. And yes, your liver could be the key to living a healthier, happier life. Siggi also shares the science and innovation behind de-liver-ance®, his groundbreaking herbal product designed to deliver the most powerful results in a safe, natural way. Backed by millions of dollars and years of research, de-liver-ance® is setting a new standard in liver health. Use code: DAVE at https://us.loveyourliver.com/discount/DAVE to get a discount! Dave and Siggi also explore cutting-edge strategies to supercharge your liver health using natural herbs, breakthrough science, and biohacking tools. What You’ll Learn: • Why your liver holds the key to longevity, energy, and mental clarity • How to reverse fatty liver disease—even if you’ve been told it’s irreversible • The truth about common liver-destroying habits you need to ditch now • Groundbreaking ways to protect and regenerate your liver for optimal health • The science behind de-liver-ance® and how it’s changing liver health forever • Simple, actionable strategies to boost detoxification and supercharge your body Resources:  2025 Biohacking Conference – https://biohackingconference.com/2025 de-liver-ance® – https://us.loveyourliver.com/discount/DAVE (Use code DAVE at checkout for a discount!) The Liver Clinic – https://theliverclinic.com Danger Coffee – https://dangercoffee.com Dave Asprey’s Website – https://daveasprey.com Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey’s Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Timestamps: • 00:00 Intro • 00:00 Introduction and Liver Basics • 01:46 Guest Introduction and Liver Health Insights • 02:16 Understanding Liver Scans and Lab Panels • 05:13 Fatty Liver Disease: Causes and Consequences • 07:07 Diet and Liver Health • 09:47 Supplements and Liver Function • 11:53 Advanced Liver Health Strategies • 14:05 Biohacking and Liver Health • 17:41 Deliverance Supplement and Its Benefits • 23:12 Liver Health and Longevity • 31:12 Biohacking: The Path to Consciousness and Longevity • 32:29 The Liver: The Body’s Regenerative Powerhouse • 34:48 Gut Microbiome and Liver Health Connection • 35:59 Lipopolysaccharides: The Hidden Toxins • 40:44 Coffee: A Surprising Ally for Liver Health • 43:16 Mold Toxins: The Silent Liver Destroyers • 48:43 Hormone Health and the Liver • 52:19 Type 2 Diabetes, Menopause, and Liver Health • 52:43 The Impact of Lifestyle on Liver Health • 54:57 The Importance of Bile and Gallbladder Health • 58:06 Genetics, Toxins, and Liver Resilience • 01:06:25 Conclusion: Investing in Liver Health for a Better Life See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Will the next nuclear bomb be AI Superintelligence? The intelligence we’re building will reshape the world in ways we never imagined—for better or worse? But more importantly, what side will humanity take? In this episode, Mo Gawdat, bestselling author of Scary Smart and former Chief Business Officer of Google X, joins Dave to tackle the profound challenges and opportunities artificial intelligence presents. This isn’t about dystopian robots or tech hype—it’s about redefining what it means to be human in the age of machines. There’s hope, don’t worry!  Mo dives into the reality of how AI is already shaping our behavior, our ethics, and even our potential for happiness. He reveals the critical need for aligning intelligence—human or artificial—with values that promote global abundance and collaboration. Dave and Mo mix data, philosophy, and bold visions, to show why our future depends on shifting from competition to cooperation. But most importantly, why all of this is going to make you a better YOU. What You’ll Learn:  • The real reason AI is reshaping human behavior—and how to take back control  • Why intelligence without ethics could lead to catastrophe  • How abundance thinking can unlock limitless possibilities for humanity  • The crucial mindset shifts leaders need to adopt before it’s too late  • Practical insights for ensuring AI supports human flourishing, not destruction Resources:  2025 Biohacking Conference – https://biohackingconference.com/2025 Mo Gawdat’s Book: Scary Smart – https://a.co/d/6DukqyW Mo Gawdat’s Book: Unstressable – https://a.co/d/hrbpY9O Follow Mo Gawdat on Instagram – https://www.instagram.com/mo_gawdat/ Danger Coffee – https://dangercoffee.com Dave Asprey’s Website – https://daveasprey.com Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey’s Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors: - Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.  - fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Timestamps:  • 00:00 The Ethical Dilemma of AI in Warfare  • 00:31 Introduction to Part Two with Mo Gawdat  • 00:58 AI and Human Happiness: A Complex Relationship  • 03:18 The Power and Responsibility of Technology  • 05:08 The Rise of AI and Its Impact on Society  • 08:31 The Future of AI: Abundance or Destruction?  • 19:53 The Role of Ethics in AI Development  • 22:39 Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Can Happiness Really Be Engineered? Mo Gawdat Says Yes—And Here’s How.  I know what you’re thinking… ANOTHER episode on happiness? Haven’t we heard it all before? This one’s different. The code is cracked, and you’re about to learn exactly how it works. Joining us today is Mo Gawdat, bestselling author of Unstressable and former Chief Business Officer of Google X. Mo sits down with Dave to deliver a practical, science-backed approach to hacking your mind and body for lasting joy. Mo dives into the raw science behind happiness and stress—revealing how your brain runs on algorithms that you can actually reprogram. Discover why dopamine might be sabotaging your joy, how to decode the four types of stress, and biohacks that can flip the script on your mental and physical resilience. He also shares the deeply personal story of how he turned unimaginable tragedy into a global mission for happiness and purpose. Mo’s insights will challenge everything you thought you knew about living a fulfilled life. What You’ll Learn:  • The happiness algorithm—and how to make it work for you  • Why dopamine addiction is robbing you of joy (and how to fix it)  • The four stress modalities and how to regain control  • Biohacks that build resilience—like cold plunges, gratitude, and micro-habits  • How small mindset shifts can create major life transformations And don’t miss Part 2, dropping in two days! Dave and Mo explore the intersection of happiness and AI, revealing how to get them both working FOR you instead of against you. Resources:  2025 Biohacking Conference – https://biohackingconference.com/2025 Mo Gawdat’s Book: Scary Smart – https://a.co/d/6DukqyW Mo Gawdat’s Book: Unstressable – https://a.co/d/hrbpY9O Follow Mo Gawdat on Instagram – https://www.instagram.com/mo_gawdat/ Danger Coffee – https://dangercoffee.com Dave Asprey’s Website – https://daveasprey.com Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey’s Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors: Neurohacker | Go to https://qualialife.com/dave and use code Dave for 15% off. Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. Timestamps: 00:00 – Intro 00:31 – Introduction to The Human Upgrade 00:45 – Dave Asprey’s AI Background 01:13 – Introducing Mo Gawdat and His Work 01:51 – From Scary Smart to Unstressable 02:40 – The Journey to Happiness 13:10 – Understanding Stress and Its Mechanisms 17:26 – The Four Modalities of Stress 24:16 – Mental Stress and the Happiness Flowchart 31:34 – Sources of Stress: Trauma, Obsessions, Noise, and Nuisances 33:27 – Understanding Modern PTSD 34:09 – The Role of Obsessions and Noise 36:24 – Biohacking for Resilience 37:58 – The Power of Gratitude 40:12 – The Happiness Equation 54:37 – Dopamine vs. Serotonin 01:03:00 – The Benefits of Cold Therapy See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Does Calorie Restriction Even Work? What About the Carnivore Diet AND Fruit?  Today we are excited to have Paul Saladino join us for a masterclass on food and diets. Dr. Saladino dives into the evolution of keto and carnivore diets, cutting through trends to focus on lasting health impacts. Dr. Saladino, widely recognized as CarnivoreMD, shares how his own diet shifted to include fruit and honey alongside animal-based nutrition, and why metabolic flexibility—not rigid rules—leads to better outcomes. Together, he and Dave challenge assumptions about long-term ketosis, examine its potential downsides, and explore how to optimize diets for energy, gut health, and longevity. They also tackle controversial topics like the risks of seed oils, the overhyped reputation of “health foods” like quinoa, and the critical roles insulin and nutrient density play in overall wellness. With insights on balancing mTOR, managing omega fats, and incorporating organ meats, this episode offers a nuanced perspective for anyone interested in biohacking, nutrition science, or simply eating smarter. What you’ll learn:  • Why metabolic flexibility matters more than strict diet rules  • The science behind long-term ketosis and insulin’s broader role in health  • How common “health foods” could be doing more harm than good  • The importance of nutrient-dense animal-based foods for gut and immune health  • How to achieve optimal balance between fat types, mTOR, and longevity markers Resources:  2025 Biohacking Conference – https://biohackingconference.com/2025 Shop Paul Saladino’s Products – https://heartandsoil.co Follow Paul Saladino on Instagram – https://www.instagram.com/paulsaladinomd/ Paul Saladino’s Book: The Carnivore Code – https://www.amazon.com/Carnivore-Code-Unlocking-Returning-Ancestral/dp/035846997X Lineage Provisions – 100% Grass-Fed Beef Tallow – https://lineageprovisions.com/products/100-grass-fed-beef-tallow Danger Coffee – https://dangercoffee.com Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ Dave Asprey’s Website – https://daveasprey.com Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey’s Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors: - Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. - LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/dave. Timestamps: • 00:00 Intro • 00:40 Paul Saladino’s Evolution in Diet • 01:21 Challenges of a Strict Carnivore Diet • 03:36 Reintroducing Carbohydrates • 05:32 Debunking Common Diet Myths • 13:49 The Problem with Calorie Restriction • 18:30 The Importance of Food Quality • 24:08 The Veganism Debate • 34:15 The Benefits of Organ Meats • 37:27 Foot Surgery and Bone Density • 39:23 Mineral Deficiency and Plant-Based Diets • 40:00 The Truth About Seed Oils • 41:10 Historical Studies on Seed Oils • 47:26 Mechanisms and Effects of Seed Oils • 52:33 Nicotine and Neuroprotection • 54:12 Oleic Acid and Longevity • 01:01:44 The Benefits of Animal Fats• 01:02:32 Odd Chain Fatty Acids and Health • 01:11:07 Cheese and Dairy Considerations • 01:13:11 The Impact of Cheese on Health • 01:14:03 Protein Intake and Longevity • 01:14:54 Understanding mTOR and Its Effects • 01:17:35 Ideal Body Fat and Metabolic Health • 01:24:38 The Role of Omega Fatty Acids • 01:32:46 ApoB, Insulin Sensitivity, and Longevity • 01:43:09 Final Thoughts and Product Recommendations  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What are the oral hygiene tips that could save your life?  Dave Asprey sits down with one of the most popular guests on the show, Naveen Jain, founder and CEO of Viome Life Sciences, to explore how your oral microbiome influences not just your dental health but your entire body. Naveen reveals groundbreaking insights into how imbalances in oral bacteria can trigger chronic inflammation, heart disease, and even cancer—and how understanding your unique microbiome can help prevent these risks. Discover why oral health goes far beyond brushing and flossing, how to optimize your oral microbiome for longevity, and why common mouthwashes may be doing more harm than good. Naveen also introduces cutting-edge solutions from Viome, including personalized oral lozenges and postbiotics, to elevate both your oral and overall health. In this episode, you’ll also uncover the exact foods to eat and avoid to live a longer, healthier, and more vibrant life. What you’ll learn in this episode:  • The surprising link between your oral microbiome and chronic disease  • Why bacterial diversity in your mouth is essential for overall health  • How leaky gums drive systemic inflammation and increase health risks  • The dangers of over-sterilizing your mouth and eliminating beneficial bacteria  • Personalized solutions to improve oral and gut health with Viome  • Actionable tips to optimize your oral microbiome for better longevity Resources:   • 2025 Biohacking Conference – https://biohackingconference.com/2025  • Viome Full Body Intelligence Test (Save $110) – https://www.viome.com/dave  • Viome Instagram – https://www.instagram.com/viome  • Learn More About Viome – https://viome.com  • Danger Coffee – https://dangercoffee.com  • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/  • Dave Asprey’s Website – https://daveasprey.com  • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books  • Dave Asprey’s Linktree – https://linktr.ee/daveasprey  • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com  • Own an Upgrade Labs – https://ownanupgradelabs.com  • Upgrade Labs – https://upgradelabs.com  • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Sponsors: -Leela Quantum | Head to https://leelaq.com/DAVE for 10% off. -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Timestamps:  • 00:00 Introduction to Viome and Its Impact on Health  • 00:53 Meet Naveen Jain: Visionary Behind Viome  • 02:41 Understanding the Microbiome and Its Role in Health  • 05:54 The Power of RNA Analysis in Personalized Health  • 12:19 Diet, Microbiome, and Personalized Nutrition  • 29:50 The Importance of Oral and Gut Health  • 39:20 Debating the Benefits of Intermittent Fasting  • 40:08 The Role of Gut Bacteria in Fasting and Diet  • 42:12 Understanding Chronic Inflammation and Diet  • 44:13 The Keto Diet Myths and Realities  • 45:44 Oxalates and Superfoods What You Need to Know  • 49:25 The Concept of Holobiont and Human Health  • 56:21 The Five Pillars of Longevity  • 01:02:04 The Importance of Quality Sleep  • 01:05:18 Purpose and Community for a Longer Life  • 01:09:48 Upcoming Topics and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Is this the missing link in fertility? The vaginal microbiome could be the most overlooked factor in optimizing women’s health, from fertility and hormonal balance to preventing infections and improving quality of life. In this groundbreaking episode, Dave Asprey talks to Priyanka Jain, co-founder and CEO of Evvy, about how understanding and improving the vaginal microbiome can transform women’s health outcomes. Priyanka shares how Evvy is advancing women’s health through cutting-edge genomic research and AI-powered insights, offering solutions to challenges like bacterial vaginosis, yeast infections, recurrent UTIs, and even infertility. You’ll learn why this critical microbiome plays such a vital role, how hormonal changes and lifestyle impact it, and how personalized approaches can improve reproductive and overall health. This episode explores not just women’s health but also how understanding the vaginal microbiome can influence relationships, biohacking, and even groundbreaking fertility research. Don’t miss this deep dive into the science and solutions shaping the future of health. Here’s what you’ll learn in this episode: • The critical role the vaginal microbiome plays in women’s health and fertility • How hormonal changes affect vaginal health and microbiome balance • The link between vaginal microbiome imbalances and conditions like bacterial vaginosis, yeast infections, and UTIs • Evvy’s innovative approach to using AI and genomics for personalized health insights • Practical tips for maintaining microbiome health, including probiotics, hydration, and hormone balance • The connection between the vaginal microbiome and overall quality of life  Resources:  • 2025 Biohacking Conference – https://biohackingconference.com/2025 • Shop at Evvy (Use coupon code DAVE for $10 off!) – https://shareasale.com/r.cfm?b=1862577&u=2810239&m=116251&urllink=&afftrack= • Follow Evvy on Instagram – https://www.instagram.com/evvy • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Sponsors: - Calroy | Head to https://calroy.com/dave for an exclusive discount. Timestamps: • 00:00 Trailer • 00:35 Introduction to Vaginal Microbiome • 01:12 Meet Priyanka Jain of Evvy • 02:03 Understanding the Vaginal Microbiome • 04:37 Challenges in Women’s Health • 09:55 Impact of Lifestyle on Vaginal Health • 11:22 The Role of Diet and Supplements • 15:24 Sexual Health and Vaginal Microbiome • 27:25 Menopause and Vaginal Health • 31:23 Optimizing Vaginal Health • 39:31 Exploring Women’s Health Data • 41:17 The Role of Vaginal Microbiome in Fertility • 43:44 Affordable Testing and Discount Offers • 45:31 The Impact of Lubricants on Vaginal Health • 46:20 Innovative Ideas for Probiotic Products • 47:29 Audience Questions and Precision Medicine • 48:04 The Importance of Data in Women’s Health • 54:31 Marketing and Misinformation in Vaginal Health • 01:06:34 The Connection Between Diet and Vaginal Health • 01:12:49 Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Is alcohol losing its grip as the go-to social drink? Enter kava—a centuries-old Polynesian plant that’s gaining global recognition for its ability to relax the mind, elevate mood, and enhance social connection without the toxic effects of alcohol. Kava, particularly in the form of TRU KAVA, is a psychoactive yet non-intoxicating drink that offers the perfect balance of calm focus and mental clarity. In this episode, Dave Asprey welcomes Cameron George, founder of TRU KAVA, to discuss why kava is becoming the drink of choice for those seeking a healthier, more connected lifestyle. Learn how kava impacts neurotransmitters like GABA and dopamine, enhances creativity and emotional grounding, and even helps the body recover from stress and trauma. Discover why kava is taking center stage in the biohacking and sober-curious movements as a new tool for wellness and connection. Here’s what you’ll learn in this episode:  • Why 41% of Americans and 61% of Gen Z are drinking less alcohol  • What kava is, how it works, and its history as a ceremonial and social beverage  • The science behind kava’s calming and neuroprotective effects  • How kava supports creativity, emotional resilience, and authentic social connection  • Practical uses for kava, including stress relief, sleep enhancement, and travel recovery  Resources:  • 2025 Biohacking Conference – https://biohackingconference.com/2025 • TRU KAVA – https://www.trukava.com • TRU KAVA Instagram – https://www.instagram.com/trukava • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Sponsors: -Quantum Upgrade |Go to https://quantumupgrade.io/Dave for a free trial. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Timestamps:  • 00:00 Intro  • 00:37 Introduction to Alcohol Trends  • 01:57 Meet Cameron George and TRU KAVA  • 02:29 What is Kava?  • 05:03 Kava’s Effects on the Brain  • 06:53 Kava vs. Alcohol  • 08:54 Active Compounds in Kava  • 10:10 Kava’s Safety and Standardization  • 16:17 Kava in Social Settings  • 21:28 Kava and Psychedelics  • 31:26 Kava for Public Speaking and Anxiety  • 34:04 Kava in the Workplace: Enhancing Team Creativity  • 35:22 Kava and Libido: The Unexpected Benefits  • 36:06 Biohacking with Kava: Energy Allocation and Community  • 39:00 Kava’s Role in Meditation and Emotional Awareness  • 42:04 Kava During Pregnancy: Safety and Traditions  • 44:37 Kava’s Neuroprotective Properties: A Deep Dive  • 45:49 Kava and EMF Sensitivity: A Surprising Connection  • 48:39 Kava for Frequent Travelers: Enhancing Mitochondrial Health  • 52:46 Kava and Metabolic Health: Fasting and Fat Burning  • 57:14 Kava Products: Oils, Beverages, and Their Uses  • 01:01:27 The Future of Kava: Social Impact and Cultural Integration  • 01:05:28 Conclusion: The Potential of Kava in Modern Society See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Have we finally discovered the key to youthful energy, longevity, and cellular health? In this episode, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer at Timeline Nutrition and a leading expert on mitochondrial health, cellular regeneration, and anti-aging science. With over 20 years of research, 50 clinical trials, and 15 patents under his belt, Dr. Singh unpacks the groundbreaking science behind Urolithin A, a revolutionary postbiotic that boosts mitochondrial function, enhances immune system resilience, and combats chronic inflammation. This episode goes beyond cutting-edge science. Dr. Singh reveals practical, real-world strategies to combat “inflammaging”—the chronic, low-grade inflammation that accelerates aging. Learn how fasting, gut health, and mitochondrial boosters like Urolithin A can rejuvenate your cells, fight fatigue, and supercharge your energy, vitality, and longevity. Here’s what you’ll learn in this episode:  • What Urolithin A is and its role in mitochondrial health and cellular energy production  • How to reverse “inflammaging” and reduce inflammation through nutrition, fasting, and biohacking  • The connection between mitochondrial dysfunction and immune system aging  • Real-life benefits of Urolithin A for energy levels, athletic recovery, skin health, and longevity  • Why mitochondrial support is critical for combating aging and improving overall performance  Resources:   • 2025 Biohacking Conference – https://biohackingconference.com/2025   • Timeline Nutrition -  https://www.timeline.com/dave to get 10% off your first order   • Timeline Instagram – https://www.instagram.com/timeline_longevity/   • Dave Asprey’s Website – https://daveasprey.com   • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books   • Danger Coffee – https://dangercoffee.com   • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/   • Dave Asprey’s Linktree – https://linktr.ee/daveasprey   • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com   • Own an Upgrade Labs – https://ownanupgradelabs.com   • Upgrade Labs – https://upgradelabs.com   • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com  Timestamps:  • 00:00 Introduction to Longevity and Mitochondria  • 01:28 The Role of Mitochondria in Immune Health  • 03:36 Understanding Inflammaging and Immune Aging  • 07:47 Measuring Immune Health and Inflammation  • 13:33 Urolithin A: A Mitochondrial Booster  • 16:46 Dosage and Effects of Urolithin A  • 26:11 Urolithin A and Exercise Performance  • 28:31 Urolithin A for Skin Health  • 31:34 Collagen and Aging: The Role of MMPs  • 33:27 Personal Experience with MMPs and Recovery  • 35:04 Measuring MMPs and Their Impact on Longevity  • 36:18 Skin Health and Urolithin A  • 38:39 Exploring Urolithin A’s Broader Benefits  • 40:33 Brain Health and Urolithin A  • 43:33 Combining Supplements for Optimal Health  • 45:54 Omega-3s and Mitochondrial Health  • 46:51 Ketones, MCTs, and Urolithin A  • 54:30 Final Thoughts on MitoPure and Supplementation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Are exosomes the planet’s ultimate healing tool?! In this episode, Dave Asprey sits down with Harvard-trained physician Dr. Edward Park to explore the groundbreaking science of exosomes. Dr. Park, a pioneer in regenerative medicine and author of Exosomes: Songs of Healing, explains how these tiny cellular messengers are revolutionizing health and longevity by bypassing the limitations of stem cells. BUT this episode isn’t just about cutting-edge science. Dr. Park also shares profound insights into life, resilience, and emotional well-being, offering advice that goes far beyond medicine. From the power of forgiveness to breaking free of limiting beliefs, his perspective blends science, spirituality, and practical wisdom for living a better life. Here’s what you’ll learn in this episode:  • How exosomes work and why they’re being called the future of regenerative medicine  • The key differences between exosomes and stem cells—and which is better for healing  • Real-life applications of exosome therapy for injuries, anti-aging, and overall health  • The potential of exosomes to enhance brain function, reduce inflammation, and promote recovery  • Dr. Park’s advice on emotional resilience, gratitude, and creating lasting change With over a decade of experience, Dr. Park shares compelling case studies, cutting-edge insights, and practical advice for anyone looking to upgrade their body, mind, and life. Whether you’re managing chronic pain, exploring anti-aging therapies, or seeking wisdom for navigating life’s challenges, this episode has something for everyone. Sponsors TRU KAVA | Go to https://trukava.com and enter code DAVE15 at checkout for 15% off  Resources: • 2025 Biohacking Conference – https://biohackingconference.com/2025 • Dr. Edward Park’s Website: Recharge Biomedical – https://www.rechargebiomedical.com • Dr. Edward Park’s Book: Exosomes: Songs of Healing – https://www.amazon.com/EXOSOMES-Songs-Healing-Ed-Park/dp/098260632X • Dr. Edward Park’s YouTube Channel – https://www.youtube.com/channel/UCpp9DlRArB1rKAWNwoouiTg • Dr. Edward Park on Instagram – https://www.instagram.com/dredpark/ • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com  Timestamps:  • 00:00 Introduction to Exosomes and Healing  • 00:48 Understanding Exosomes: Stem Cell Communication  • 01:19 Dr. Edward Park’s Insights on Exosomes  • 02:47 Exosomes vs. Traditional Treatments  • 04:44 Exosomes in Regenerative Medicine  • 07:33 Cost-Effective Regeneration Protocols  • 12:35 Exosomes for Hair Growth  • 14:37 Stem Cells and Brain Health  • 25:33 Banking Stem Cells for Future Use  • 35:27 Epigenetic Age and Longevity Predictors  • 37:48 CRISPR and Gene Editing: Risks and Benefits  • 39:43 Basic Health Tips for Longevity  • 41:02 Spirituality, Past Lives, and Healing  • 42:50 Questioning Medical and Political Narratives  • 47:54 The Importance of Free Speech  • 01:07:40 The Role of Intuition in Medicine  • 01:09:22 Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Is biohacking your sweat the secret to vitality? Dave Asprey dives into the transformative world of infrared saunas with Connie Zack, founder of Sunlighten and a 25-year innovator in the space. Together, they uncover how targeted light and heat therapy can unlock unparalleled health benefits, from detoxing heavy metals to energizing your body at the cellular level. Here’s what you’ll learn in this episode: • Why infrared saunas excel at detoxing heavy metals and toxins • How they mimic exercise to boost cardiovascular health and recovery • The science behind infrared’s impact on mitochondrial energy and longevity • Surprising benefits for gut health, inflammation, and hormone balance • Hacks to get the most out of your infrared sauna sessions Connie shares cutting-edge research and personal insights, offering practical ways to integrate infrared therapy into your routine. Whether you’re looking to recover faster, improve your mood, or support long-term health, this episode delivers the tools you need to take your biohacking game to the next level. Special Offer: Use code “DAVE” at sunlighten.com to get up to $1,000 off until December 6th! Sponsors:-ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. -fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Resources: • Sunlighten Saunas Website – https://www.sunlighten.com/dave/?utm_source=DaveAsprey&utm_medium=Partner&utm_content=Podcast&leadsource=DaveAsprey&utm_campaign=DaveAsprey • Sunlighten Saunas on Instagram – https://www.instagram.com/sunlightensaunas/    • 2025 Biohacking Conference – https://biohackingconference.com/2025 • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Timestamps  • 00:00 Introduction to Infrared Saunas • 00:27 Meet Connie Zack: Leading Voice in Infrared Saunas • 00:50 The Science Behind Infrared Saunas • 02:35 Infrared Saunas vs. Traditional Saunas • 05:41 Health Benefits of Infrared Saunas • 08:14 Technological Advancements in Infrared Saunas • 17:36 The Role of LEDs in Infrared Saunas • 22:37 Practical Tips and Personal Experiences • 28:14 Detoxing and Energizing with Glutathione • 28:40 Pre and Post-Sauna Rituals • 29:05 Habit Stacking in the Sauna • 29:41 Managing Overheating Devices • 31:05 Creative Breakthroughs in the Sauna • 32:14 Scientific Method and Personal Experience • 36:05 Understanding Glucose Spikes • 38:44 Longevity Benefits of Infrared Saunas • 43:27 Infrared Saunas and Skin Health • 45:29 Extreme Detox Protocols • 48:28 Grip Strength and Longevity • 50:34 Customizing Your Sauna Experience See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if you could command any room and set boundaries without saying a word? Dave Asprey sits down with Kasia Urbaniak, founder and CEO of The Academy—a trailblazing school where women learn the true principles of influence and authority. Kasia brings a unique and dynamic perspective, drawing on nearly two decades of experience that includes working as a professional Dominatrix, practicing Taoist alchemy in one of China’s oldest female-led monasteries, and earning certifications across disciplines like Medical Qi Gong and Systemic Constellations. Here’s what you’ll learn in this episode: • How to set clear, unbreakable boundaries in any situation • Techniques for wielding influence without sacrificing integrity • Tools to reclaim inner authority and navigate life with confidence • Practical strategies for handling power dynamics in relationships, work, and beyond Kasia’s methods have empowered over 4,000 women worldwide to step into leadership roles in every sphere, from personal relationships to professional arenas. In this episode, she shares practical insights on transforming how you’re perceived by others and, more importantly, how you perceive yourself. Whether you’re navigating complex workplace dynamics, strengthening personal boundaries, or seeking clarity in relationships, Kasia’s teachings offer a path to reclaiming the powerful, authentic authority within you. Sponsors -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.  -LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/dave.  Resources: • 2025 Biohacking Conference – https://biohackingconference.com/2025 • Kasia Urbaniak’s Website – https://www.kasiaurbaniak.com • Kasia Urbaniak’s Book: Unbound: A Woman’s Guide to Power – https://www.kasiaurbaniak.com/unbound • The Academy – Practical Training for Women on Power and Influence – https://www.kasiaurbaniak.com/the-academy • Kasia Urbaniak on Instagram – https://www.instagram.com/kasiaurbaniak/ • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Timestamps: • 00:00 Introduction to the Human Upgrade • 01:07 Meet Kasia Urbaniak: Author of Unbound • 02:52 Exploring Power Dynamics • 04:46 The Role of Emotions in Power • 14:50 Embodiment and Somatic Work • 32:58 The Power of Voice and Presence • 48:22 Collective Intelligence and Intuition • 54:50 Facing Fears and Intuition • 55:15 Male vs. Female Intuition • 56:01 The Power of Erotic Energy • 57:13 Welcoming Emotions and States • 59:10 Role-Playing and Personas • 01:00:06 Teaching Women to Speak Up • 01:02:04 Energetic Dynamics in Relationships • 01:04:35 Victimhood and Healing • 01:19:54 The Power of Asking • 01:29:40 Money and Emotional Alchemy • 01:31:53 Shameless Money Conversations • 01:44:00 Final Thoughts and Upcoming Events See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Is unlocking the full potential of your brain even possible, or just a myth from the movie Limitless? In this eye-opening episode, neuroscientist and author Dr. Mithu Storoni joins Dave to dive deep into the science of brain optimization for hyper-efficient work performance. Together, they break down the surprising roles of astrocytes in supporting neurons, the influence of the brain’s “blue dot” region (the locus coeruleus) on focus and mental clarity, and how harnessing neuroplasticity can lead to improved cognitive efficiency and resilience in high-stress environments. Get ready to discover actionable science-backed hacks for enhancing work productivity and maintaining focus—even in the face of constant distractions. Dr. Storoni also explains how optimizing your breathing rhythm, managing your brain’s arousal state, and tapping into the natural flow of ultradian rhythms can dramatically improve your mental output. Whether you’re looking to elevate your workflow, supercharge your mental performance, or unlock the science of hyper-efficiency, this episode delivers essential strategies to cultivate a high-performing mind for work and beyond. Tune in to understand how the latest neuroscience can transform how you think, focus, and excel every day. Sponsors -Quantum Upgrade | Go to Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. Resources: • Dr. Mithu Storoni’s Website – https://www.mithustoroni.com • Hyper Efficient: Optimize Your Brain to Transform the Way You Work by Dr. Mithu Storoni – https://www.hachettebookgroup.com/titles/mithu-storoni/hyperefficient/9780316566933/ • Dr. Mithu Storoni on Facebook – https://www.facebook.com/drmithustoroni/ • Dr. Mithu Storoni’s LinkedIn – https://www.linkedin.com/in/mithu-storoni-0488872a/ • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Timestamps • 00:00 – Introduction to Brain Complexity • 00:29 – The Human Upgrade with Dave Asprey • 01:42 – Meet Dr. Mijtu Storoni • 02:16 – Understanding Brain Efficiency • 02:57 – The Role of Astrocytes • 04:37 – Brain Adaptability and Environment • 06:55 – Biohacking and Environmental Signals • 08:34 – Power vs. Efficiency Debate • 11:26 – The Importance of Glial Cells • 18:10 – The Brain as a Predictive Machine • 23:14 – Nutrition and Brain Health • 32:33 – The Gut-Brain Connection • 36:36 – Eye Health as a Proxy for Brain Health • 40:47 – Aligning the Brain: The Blue Dot Network • 41:54 – Understanding Brain Gears and Stress Management • 42:27 – Maintaining the Goldilocks Zone for Optimal Brain Function • 43:09 – The Role of Creativity and Daydreaming • 44:28 – Strategies to Stay in Optimal Mental States • 47:44 – Biohacking for Enhanced Efficiency • 51:00 – The Science Behind Flow States • 57:09 – Harnessing Innate Curiosity for Mental Efficiency • 01:03:46 – Breathing Techniques for Mental Regulation • 01:13:32 – The Importance of Ultradian Rhythms • 01:17:40 – Practical Tips for Efficient Breaks • 01:21:20 – Conclusion: Embracing Hyper Efficiency See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if the keys to an extraordinary life lie in choices most people wouldn’t dare to make? In this iconic, unearthed episode, best-selling author and performance pioneer Tim Ferriss joins Dave Asprey to spill the unfiltered truth on smart drugs, insect protein, and the surprising links between sex, creativity, and high performance. They dig into cutting-edge topics still sparking curiosity today: the calculated risks and rewards of smart drugs, the future-forward benefits of insect protein, and how unconventional habits fuel creativity and peak performance. Tim candidly shares his personal protocols, from routine blood testing to strategic supplementation, all rooted in his philosophy that “the dose makes the poison.” As a powerful wrap-up, Tim lays out his top three life principles for real success: choosing high-caliber people, focusing on those who “get it,” and setting audacious, even wild, goals. Whether you’re biohacking or simply intrigued, this episode delivers timeless insights and bold ideas for anyone ready to unlock a high-performance life. Sponsors -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.  -Pendulum | Go to https://pendulumlife.com/ and use code Asprey20 for your first month of GLP-1 or any Pendulum formula. Resources:  • Tim Ferriss’ Website – https://tim.blog  • Tim Ferriss’ Book Club – http://fourhourbook.club/  • Tim Ferriss’ Podcast – https://tim.blog/podcast/  • Dave Asprey’s Website – https://daveasprey.com  • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books  • Danger Coffee – https://dangercoffee.com  • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/  • Dave Asprey’s Linktree – https://linktr.ee/daveasprey  • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com  • Own an Upgrade Labs – https://ownanupgradelabs.com  • Upgrade Labs – https://upgradelabs.com  • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Timestamps  • 00:00 Introduction to Early Episodes  • 00:57 The Human Upgrade with Tim Ferriss  • 01:58 Smart Drugs and Their Effects  • 05:09 Experimenting with Health and Performance  • 13:53 The Role of Creativity and Writing  • 17:05 Exploring Nutrition and Insect Protein  • 21:01 Handling Criticism and Audience Responsibility  • 30:04 Sex, Performance, and Longevity  • 33:21 Tim Ferriss’ Top Three Life Tips   See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if everything you believe about happiness is wrong? In this episode, Harvard professor and world-renowned happiness expert Arthur Brooks joins Dave Asprey to unlock the secrets of real happiness, revealing the science behind joy, resilience, and lasting fulfillment. As a bestselling author and co-author with Oprah Winfrey of Build the Life You Want, Arthur has spent decades helping people rethink happiness through a blend of psychology, neuroscience, and ancient wisdom. Together, Dave and Arthur explore eye-opening topics like the “reverse bucket list,” why dopamine-driven goals often lead to disappointment, and how embracing discomfort can actually create deeper contentment. Arthur dives into why our common pursuits of fame, wealth, and success often fall short, and shares powerful strategies for mastering what’s within our control, building resilience, and finding meaning in life’s simplest moments. From managing dopamine to harnessing the power of small wins, this episode offers science-backed insights and practical tools to elevate your life with lasting joy and purpose. If you’re ready to transform your approach to happiness, tune in for strategies that truly work.  Sponsors Leela Quantum | Head to https://leelaq.com/DAVE for 10% off. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources:  • Arthur Brooks’ Website – https://arthurbrooks.com  • Arthur Brooks’ TED Talk: A New Way to Think About Happiness – https://www.ted.com/talks/arthur_brooks_the_art_and_science_of_happiness?subtitle=en&geo=es • Arthur Brooks’ Weekly Column: How to Build a Life in The Atlantic – https://www.theatlantic.com/author/arthur-c-brooks/  • Dave Asprey’s Website – https://daveasprey.com  • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books  • Danger Coffee – https://dangercoffee.com  • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/  • Dave Asprey’s Linktree – https://linktr.ee/daveasprey  • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com  • Own an Upgrade Labs – https://ownanupgradelabs.com  • Upgrade Labs – https://upgradelabs.com  • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com    Timestamps • 00:00 – Introduction to Reverse Bucket List • 00:35 – The Science of Happiness • 00:58 – Personal Journey to Happiness • 01:44 – Meet Arthur Brooks • 04:26 – The Role of Music in Emotions • 07:43 – Understanding Emotions and the Brain • 09:50 – Parenting and Influence • 18:06 – Public Speaking and Performance • 34:10 – Striving for Success and Happiness • 39:40 – The Struggle with Body Image and Nutrition • 40:03 – Reverse Bucket List: Assessing Attachments • 40:57 – The Science of Dopamine and Motivation • 43:09 – The Dangers of Pornography and Dopamine • 44:03 – Biohacking and Pain Management • 47:03 – The Importance of Small Wins • 48:48 – Embracing Pain and Discomfort • 53:01 – The Role of Pain in Personal Growth • 56:12 – The Concept of Non-Resistance • 57:17 – The Happiness of Strivers • 01:01:13 – The Importance of Relationships and Spiritual Life • 01:03:22 – The Role of Fame and Legacy • 01:16:31 – The Value of Truthfulness and Compassion • 01:17:59 – Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Explore the science and potential of hypnosis as Dr. David Spiegel, Stanford’s leading expert in mind-body medicine, joins Dave Asprey to reveal how hypnosis can radically enhance cognition, mental clarity, and resilience. In this episode of The Human Upgrade, you’ll learn how hypnosis influences the brain’s most vital networks, including the default mode network and executive control, to break mental barriers and amplify focus, perception, and healing. Discover how hypnosis, unlike traditional meditation or neurofeedback, accelerates response times, manages pain, and even helps alleviate PTSD. Dr. Spiegel shares stories of patients overcoming chronic pain and trauma through self-hypnosis, and details the mechanisms that make hypnosis a powerful tool for emotional and physical transformation. Dive into the fascinating brain science behind the practice, from theta brainwave induction to deep sensory modulation, and learn simple self-hypnosis techniques that can elevate mental performance, improve sleep quality, and instill lasting calm. If you’re seeking a powerful, accessible way to biohack your brain and harness the potential of your mind, this episode delivers the insights and tools you need to make hypnosis your ultimate cognitive upgrade.   Sponsors Quantum Upgrade | Go to Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Dr. David Spiegel’s Website – https://med.stanford.edu/profiles/david-spiegel • Reveri Hypnosis App – https://reveri.com (available on App Store and Google Play) • Dave Asprey’s Website – https://daveasprey.com • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement https://40yearsofzen.com Timestamps • 00:00 – Introduction to Hypnosis • 00:59 – Dave Asprey Introduces Dr. David Spiegel • 02:03 – Dr. Spiegel’s Journey into Hypnotherapy • 06:06 – The Power of Hypnosis in Medical Practice • 11:19 – Understanding Hypnosis and Brain Function • 16:14 – Hypnosis for PTSD and Trauma • 19:33 – Hypnosis vs. EMDR: Key Differences • 22:30 – Pain Management through Hypnosis • 31:06 – The Impact of Psychedelics on Cancer Patients • 33:04 – Exploring Psychedelic-Assisted Neurofeedback • 34:05 – Neuroimaging and Brain Activity in Hypnosis • 35:22 – Hypnosis and Cognitive Enhancement • 38:53 – Hypnosis for Sleep and Stress Management • 42:26 – Hypnosis and the “Manchurian Candidate” Concept • 48:21 – Hypnosis and the Immune System • 53:11 – Live Hypnosis Session with Dave Asprey • 58:46 – Conclusion and Final Thoughts  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Unlock the mastermind secrets to cognitive enhancement as Dave Asprey shares his ultimate brain-boosting biohacks in this powerful episode of The Human Upgrade. Discover how Dave elevated his IQ, reversed Asperger’s, and overcame brain fog through advanced neurofeedback, BDNF-boosting supplements, mitochondrial enhancers, and the power of the groundbreaking 40 Years of Zen program. Explore revolutionary techniques, from ancient meditation practices to modern nootropics and smart drugs, all designed to amplify memory, focus, and resilience. Learn the science behind cognitive enhancement, from ketones like C8 MCT oil to essential supplements like Vitamins D, K, A, and magnesium that fuel optimal brain function. If you’re seeking proven methods to enhance neuroplasticity, boost mental endurance, or reduce brain fog, this episode is packed with actionable insights. Whether you’re aiming to maximize mental performance or unlock the latest in brain science, Dave’s mastermind approach offers a comprehensive guide to upgrading your mind and achieving peak potential. Prepare to boost cognitive abilities, harness your mind’s true power, and achieve new levels of clarity with Dave’s most effective brain and body biohacks—culminating in the transformative experience of 40 Years of Zen. Sponsors40 Years of Zen | Neurofeedback training for advanced cognitive enhancement https://40yearsofzen.com/upgrade/Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.Pendulum | Go to https://pendulumlife.com/ and use code Asprey20 for your first month of GLP-1 or any Pendulum formula.Resources: • Dave Asprey’s Website – https://daveasprey.com • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • Mendi Neurofeedback Device – Home neurofeedback device for attention and focus improvement https://www.mendi.io • Ketone IQ by HVMN – Go to https://ketone.com/dave for 30% off your first subscription of Ketone IQ.• Qualia NAD – Support for mitochondrial function and cellular energy https://qualialife.com/dave (use code DAVE for discounts) • Vitamin DAKE – Fat-soluble vitamin complex designed by Dave Asprey https://vitamindake.com • Minerals 101 – Comprehensive mineral supplement for cognitive and metabolic support https://shopsuppgradelabs.com/products/minerals-101  Timestamps: • 00:00 Intro • 00:32 Introduction to Cognitive Enhancement • 01:41 Dave’s Personal Journey and Struggles • 04:15 Discovering Cognitive Enhancement Tools • 11:36 Exploring Neurofeedback and Brain Training • 14:22 The Power of Mitochondria and Neuroplasticity • 23:45 Supplements for Cognitive Enhancement • 32:33 The Role of NAD+ in Brain Function • 34:41 Foundational Supplements for Brain Health • 36:17 Essential Supplements for Cognitive Function • 37:29 The Importance of Magnesium and Zinc • 39:14 Meditation and Breath Work for Brain Health • 40:07 Avoiding Toxins for Better Brain Function • 42:56 The Impact of EMFs on Brain Health • 46:25 Neurofeedback and Cognitive Enhancement • 01:05:01 The Power of Ketamine in Neurofeedback • 01:09:49 Final Thoughts and Recommendations • 01:09:49 Testimonials  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Unlock the secret to cellular detox and discover how to cleanse your body from the inside out with Dave Asprey and Jessica Berman in this episode of The Human Upgrade. Explore cutting-edge detox strategies using phosphatidylcholine, Tudca, and butyrate, three powerful molecules designed to remove toxins, microplastics, and endocrine disruptors from your system. Jessica, co-owner of BodyBio, reveals how these products support not just detoxification, but also optimize mitochondrial function, enhance brain performance, and improve overall cellular health. From phosphatidylcholine’s ability to restore cell membranes to Tudca’s role in liver health, you’ll learn how to protect yourself from the daily onslaught of environmental toxins that can harm your longevity and vitality. If you’ve been searching for how to reduce your toxic load, flush out microplastics, or boost cognitive function, this episode is packed with actionable insights. Whether you’re a biohacker looking to enhance your cellular resilience or someone curious about how these supplements can improve your overall health, this episode will take your detox game to the next level. Get ready to learn how to detox like a pro, rebuild your cell membranes, and optimize your brain and body with these game-changing biohacks! Resources:  • BodyBio Phosphatidylcholine, Tudca, Butyrate & More – Get 25% off BodyBio products with code DAVEASPREY https://bodybio.com/collections/dave-asprey?affluencerId=Dave%20Asprey&linkId=Dave%20Asprey_Clear%20It%20All_Podcast• Dave Asprey’s Website – https://daveasprey.com • The Human Upgrade Podcast – https://daveasprey.com/category/podcasts/ • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.comTimestamps: • 00:00 Intro • 00:30 Introduction and Importance of Grass-Fed Barbecue • 01:03 The Ubiquity of Environmental Toxins • 01:39 Minimizing Exposure and Detoxification • 02:47 Introducing Jessica Berman and BodyBio • 04:41 Understanding Cell Membranes • 08:55 Phosphatidylcholine and Its Benefits • 27:54 Clinical Observations and Future Research • 36:49 The Reality of Modern Toxins • 37:00 Understanding Lipophoric Toxins • 37:44 Detoxification Strategies • 38:30 The Role of Phospholipids • 39:16 Liver Health and Detox • 40:29 The Benefits of Tudca • 41:24 Choline and Fatty Liver • 42:20 Debunking TMAO Myths • 44:28 Soy Lecithin vs. Sunflower Lecithin • 47:21 Mitochondrial Health and Prenatal Care • 50:03 Biohacking for Healthy Aging • 55:35 The Importance of Phospholipids for Cognitive Health • 59:12 Mold Toxins and Health • 01:01:45 Building Resilient Humans • 01:05:02 Exclusive Offer for Listeners See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Step into the future of sports performance with The Human Upgrade as Dave Asprey and Aron D’Souza, founder of the Enhanced Games, uncover the controversial world of steroids, gene therapy, peptides, and human enhancement. In this groundbreaking episode, they explore how athletes can push the boundaries of physical and mental performance by embracing cutting-edge science once banned by traditional sports bodies like the Olympics. Discover why the Enhanced Games are redefining fairness in athletics, allowing competitors to use biohacking and performance-enhancing technologies to unlock new levels of strength, speed, and recovery. Aron breaks down the ethical dilemmas, the science behind enhancements, and why athletes should have full control over their bodies and biology. From synthetic growth hormones to the latest in gene therapy, this episode dives deep into the future of sports innovation. Whether you’re fascinated by the world of biohacking, curious about the next big revolution in sports, or want to understand how gene therapy and performance enhancers could impact human longevity, this episode delivers a thought-provoking look into the possibilities of superhuman performance. Could you be the world’s next super athlete? Age might soon be irrelevant! The future of athletic potential is wide open—are you ready to take the leap? Sponsors: Omni-Biotic | Visit omnibioticlife.com/dave and use code DAVE20 for 20% off. Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide.  Resources:  • Enhanced Games – https://enhanced.org  • Enhanced Games Instagram – https://www.instagram.com/enhanced_games/  • Dave Asprey’s Website – https://daveasprey.com  • The Human Upgrade Podcast – https://daveasprey.com/category/podcasts/  • Gene Therapy for Longevity – https://daveasprey.com/genetherapy  • Danger Coffee – https://dangercoffee.com  • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/  • Dave Asprey’s Linktree – https://linktr.ee/daveasprey  • Dave Asprey’s Book Smarter Not Harder – https://daveasprey.com/books  • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com  • Own an Upgrade Labs – https://ownanupgradelabs.com  • Upgrade Labs – https://upgradelabs.com Timestamps:  • 00:00 – The Toxic Belief System  • 00:31 – Introduction to the Human Upgrade  • 02:42 – The Enhanced Games Concept  • 04:12 – Olympic Inequality and Corruption  • 05:19 – The Case for Performance Enhancements  • 10:54 – Transparency and Financial Incentives  • 15:30 – Health and Safety in Enhanced Games  • 18:14 – Global Impact and Future of Enhanced Games  • 25:28 – Cognitive vs. Physical Enhancements  • 28:54 – Historical Context and Future Vision  • 33:54 – Human Enhancements and Banned Substances  • 34:36 – The Enhanced Games: Concept and Vision  • 35:53 – Biohacking and Cognitive Enhancers  • 36:24 – The Birth of the Enhanced Games  • 37:00 – Data and the Future of Sports  • 40:20 – Criticism and Scientific Debate  • 42:03 – Ethics and Sponsorship  • 47:55 – Gender and Competition Categories  • 54:41 – Funding and Logistics of the Enhanced Games  • 57:06 – The Future of Sports and Human Potential  • 57:46 – Technological and Engineered Enhancements  • 01:04:16 – Getting Involved and Final Thoughts  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Unlock the power of continuous glucose monitoring (CGM) and transform your health in this eye-opening episode with Dave Asprey. Discover why tracking your blood sugar 24/7 isn’t just for diabetics—it’s the key to unlocking peak health, optimizing your metabolism, and preventing chronic diseases. Joined by Levels founder and biohacker Josh Clemente, Dave dives into the real science behind CGMs and how they provide unparalleled insights into how your diet, sleep, and exercise affect your blood glucose. You’ll learn how glucose spikes are linked to aging, inflammation, and energy crashes, and why keeping your blood sugar stable can help you boost mental clarity, enhance longevity, and even prevent conditions like diabetes and heart disease. Josh reveals the engineering mindset behind building Levels and how this game-changing technology is revolutionizing the way we understand metabolic health. With insider data from 50,000+ users, you’ll discover how simple lifestyle tweaks—like post-meal walks, sleep optimization, and personalized nutrition—can dramatically improve your health outcomes. This episode is a must-listen for anyone serious about biohacking, metabolic control, and optimizing every aspect of their health through real-time data. Learn how to take control of your body and get ahead of the game in the future of health monitoring. Sponsors: Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. OneSkin | Go to https://oneskin.co/ and use code ASPREY15 for 15% off your purchase.  Resources: • Levels: Visit https://levels.link/daveasprey to get two extra months of membership with Levels. • Levels Instagram: https://www.instagram.com/levels • Josh Clemente Instagram: https://www.instagram.com/joshuasforrest • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Dave Asprey’s Book Smarter Not Harder: https://daveasprey.com/books • Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ • Upgrade Collective: Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com Timestamps: • 00:00 - Introduction to Personal Data Rights • 00:38 - The Importance of Blood Sugar Monitoring • 01:16 - Dave Asprey’s Journey with Glucose Monitoring • 02:47 - The Evolution of Continuous Glucose Monitors • 03:31 - Installing the New Levels Sensor • 04:39 - The Role of Data in Biohacking • 05:47 - From SpaceX to Glucose Monitoring • 09:49 - The Need for Better Health Data • 13:25 - The Intersection of Engineering and Health • 20:25 - The Future of Personalized Health Data • 28:46 - The Impact of Continuous Glucose Monitoring • 35:45 - Levels’ Research and Findings • 40:28 - Understanding Food Logging and Blood Sugar Response • 41:14 - The Struggle with Weight Loss and Willpower • 41:56 - The Role of Different Foods in Blood Sugar Management • 44:32 - Biohacking and Personalized Nutrition • 49:30 - The Impact of Sleep on Blood Sugar Control • 55:23 - The Future of Health Monitoring and AI • 59:19 - Practical Tips for Blood Sugar Management • 01:02:01 - The Importance of Tracking Health Metrics • 01:15:35 - Blood Sugar and Cognitive Function • 01:21:01 - Final Thoughts and Recommendations   See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Get ready to discover the true superfoods that can transform your health—starting with spirulina and chlorella. In this dynamic and thought-provoking episode, Dave Asprey welcomes Catharine Arnston, founder of ENERGYbits, to dive deep into the world of algae and its incredible potential to boost energy, detox the body, and support longevity. First, we challenge the myths around trendy “superfoods” and reveal why algae, particularly spirulina and chlorella, reign supreme for mitochondrial health and cellular energy. Catharine shares her 15 years of research on algae, explaining how it protects your cells, enhances brain function, and even supports cancer prevention. Next, we explore cutting-edge science on how algae supercharge mitochondrial performance, with Catharine revealing new clinical trial data that shows a 20% boost in mitochondrial function in just seven days. Finally, we break down the real-life impacts—improved brainpower, glowing skin, and detoxified cells—showing how this powerhouse algae can revolutionize the way you think about your health. This episode will change the way you approach superfoods and biohacking forever. Resources: ENERGYBits: Visit energybits.com and use code UPGRADE for 20% off your order. ENERGYbits Instagram: https://www.instagram.com/energybits/ Dave Asprey’s Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book Smarter Not Harder: https://daveasprey.com/books Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Join The Human Upgrade Podcast Live – Upgrade Collective: https://www.ourupgradecollective.com Own an Upgrade Labs: https://ownanupgradelabs.com  Timestamps:  • 00:00 – You Won’t Believe This  • 00:39 – Introduction to Superfoods  • 01:24 – The Benefits of Algae  • 02:20 – Guest Introduction: Catharine Arnston  • 03:19 – Catharine’s Journey to Algae  • 04:16 – The Science Behind Algae  • 05:22 – Mitochondria and Algae  • 05:53 – The Role of Superoxide Dismutase (SOD)  • 06:24 – Alkaline Diets and Health  • 22:20 – Phycocyanin: The Cancer-Fighting Pigment  • 29:52 – Clinical Trials and Future Research  • 31:31 – Spirulina Efficacy Study  • 32:12 – Mitochondrial Health Insights  • 32:56 – Intermittent Fasting vs. Spirulina  • 35:27 – Testimonials and Real-Life Benefits  • 39:52 – Quality Control and Safety  • 43:31 – Skin Health and Algae  • 47:34 – Dosing and Usage Tips  • 48:18 – Brain Health and Recovery  • 50:57 – Aging and Biohacking  • 53:39 – Final Thoughts and Offers See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, we’re diving into the age old question, what is the purpose of your life? We chat about the science behind emotional intelligence with Dr. John Demartini, creator of the groundbreaking Demartini Method. In this thought-provoking episode, Dr. Demartini reveals how his unique approach to personal development and emotional mastery can help you uncover your highest values and transcend emotional chaos. We explore how the quality of the questions you ask shapes the quality of your life, providing a roadmap to unlock your fullest potential. First, we dig into the hidden order of the universe, showing how the Demartini Method guides you to balance emotion, intuition, and inspiration for greater control and fulfillment in life. Then, we break down Dr. Demartini’s journey—overcoming learning challenges, mastering the mind-body connection, and developing a method that has transformed lives around the globe. Finally, Dr. Demartini shares actionable strategies for tapping into your innate brilliance, balancing your values, and discovering the magnificence already within you. This episode will shift your perspective on personal growth, purpose, and the power of self-awareness. Sponsors: ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order.  Quantum Upgrade | Go to Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial.  Resources: Dr. John Demartini’s Website: https://drdemartini.com/ Dr. John Demartini’s Instagram: www.instagram.com/drjohndemartini Dr. John Demartini’s YouTube: www.youtube.com/c/drdemartini Dave Asprey’s Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com Join The Human Upgrade Podcast Live – Upgrade Collective: https://www.ourupgradecollective.com Own an Upgrade Labs: https://ownanupgradelabs.com Timestamps and Highlights: • 00:00 - Introduction to Dr. John Demartini • 01:56 - The Demartini Method Explained • 04:53 - Delegating and Managing Stress • 08:19 - Journey to Mastery and Overcoming Challenges • 15:08 - The Power of Reading and Learning • 22:57 - Transforming Education in South Africa • 28:39 - Integration of Knowledge and Universal Principles • 34:23 - Understanding Emotions and Intuition • 35:09 - The Role of Intuition in Awareness • 35:41 - Inspiration and Full Consciousness • 37:31 - The Hidden Order in the Universe • 40:17 - The Concept of Divine Guidance • 45:52 - The Neuroscience of Divine Order • 54:56 - The Demartini Method and Human Behavior • 59:18 - Applying the Demartini Method • 01:05:00 - The Breakthrough Experience • 01:07:49 - Final Thoughts and Gratitude See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, we’re unlocking the full potential of your brain—starting with Bryan Johnson’s Blueprint for longevity and brain optimization. We’re revisiting our conversation with Bryan, the creator of the Don’t Die movement (among many other things), to explore how his groundbreaking approach to brain health and biohacking is reshaping the future of longevity. First, we dive into Bryan’s mission to make brain monitoring as easy as tracking blood glucose, using his Blueprint protocol to measure and optimize cognitive performance for better health and wellness. Then, we tackle the deeper side of biohacking—longevity, societal reactions to living longer, and how to handle critics when you’re pushing the limits of human potential. Finally, Bryan shares his personal journey—investing $80M into brain science, building the Blueprint for optimal living, and discovering the power of community and lifelong friendships for a long, vibrant life. This episode will change the way you think about brain health and the future of humanity. Sponsors: Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. Resources: Bryan Johnson’s Blueprint Protocol: https://blueprint.bryanjohnson.com/ Bryan Johnson’s Don’t Die Movement: https://dontdie.bryanjohnson.com/ Bryan Johnson’s Kernel: https://www.kernel.com/ Bryan Johnson’s YouTube Channel: https://www.youtube.com/@bryanjohnson_ Bryan Johnson’s Instagram: https://www.instagram.com/bryan_johnson_ Dave Asprey’s Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com Join The Human Upgrade Podcast Live – Upgrade Collective: https://www.ourupgradecollective.com Own an Upgrade Labs: https://ownanupgradelabs.com Timestamps and Highlights: 00:00 Introduction and Bold Claims 00:39 Meet Bryan Johnson: The Neuroscience Pioneer 01:23 Kernel: Revolutionizing Brain Measurement 05:51 Biohacking and Longevity 07:30 Facing Criticism and Staying Resilient 16:06 Media Training Insights 19:49 Personal Reflections and Relationships 34:37 Exercise and Longevity 44:46 Optimizing Brain-Body Interface 45:25 Longevity Hacks and Driving Preferences 45:48 Debating Olive Oil and Saturated Fats 46:52 The Blueprint Approach to Health 48:38 Testing and Metrics in Health 52:22 Testosterone and Hormone Protocols 56:27 Exploring Semen Retention 01:00:44 Body Hair and Aesthetics 01:04:26 Psychedelics and Consciousness 01:08:32 Audience Q&A and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, we’re diving deep into biohacking your body’s performance—starting with your VO2 max and mitochondria. We’re sitting down with cellular optimization expert, Rowena Gates, to dive into how the NanoVi device is disrupting the world of biohacking, recovery, and training. First up, we’re breaking down VO2 max—the secret sauce to longevity. Forget endless hours of cardio. Learn how to hack your VO2 max efficiently and add years to your life, without grinding it out in the gym. Then, we tackle the hidden world of reactive oxygen species (ROS). These little molecules can be both your friend and foe—boosting energy or fast-tracking aging. We’ll show you how to control them, so you can keep your energy levels high and your body youthful. Finally, we explore the cutting-edge science of protein folding and exclusion zone water. Sound complicated? Don’t worry, we’ll break it down and show how NanoVi tech supercharges your mitochondria, giving you faster recovery and more endurance, all with minimal effort. Sponsors: Eng3 Special Offer Code: https://eng3corp.com/dave/ Resources: Rowena Gates’ Website: https://www.eng3corp.com NanoVi Device: https://www.eng3corp.com/nanoviRowena Gates’ LinkedIn: https://www.linkedin.com/in/rowenagates/ Dave Asprey’s Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com Join The Human Upgrade Podcast Live – Upgrade Collective: https://www.ourupgradecollective.com Own an Upgrade Labs: https://ownanupgradelabs.com Timestamps and Highlights: 00:00 Introduction to Metabolic Health 00:38 The Importance of VO2 Max 02:34 Reactive Oxygen Species Explained 05:57 The Role of Water in Cellular Health 14:11 Mitochondrial Function and Longevity 20:25 Cognitive Function and Biohacking 21:45 Advanced Meditation and Mitochondria 22:09 Post-Exercise Recovery Insights 22:37 NanoVi and Athletic Performance 23:42 Pro Athletes and Biohacking 27:00 Mitochondrial Function and Health 33:24 NAD and Cellular Health 36:29 Biohacking for Modern Living 37:48 Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, we’re hacking your home—big time. I’m sitting down with three experts who know exactly how your living space might be messing with your health, and more importantly, how to fix it. First up, we’ve got Michael Rubino, aka the mold medic, who’s here to blow your mind about the invisible toxins lurking in your walls. Mold? It’s everywhere, and it’s doing more damage than you think. Michael’s got killer insights on why dust might be your biggest health enemy and exactly how to get rid of it before it starts messing with your system. Then, we’ve got Ryan Blaser dropping some serious science on environmental toxins you probably didn’t even know were impacting you. EMFs? VOCs? Ryan explains why your home’s air quality might be worse than you think, and how to fix it with a few smart biohacks. Finally, Matteo Franceschetti, the sleep optimization guru, breaks down how your home could be trashing your sleep. He’s got the secrets to transforming your environment so you can supercharge your recovery and performance every night. Check out the Full Episodes here:  • Detox Your Home: How to Improve Indoor Air Quality & Get Rid of Mold – Michael Rubino | 1036 https://www.youtube.com/watch?v=gncPqFlRXho&t=2s • How Mold Affects Your Health & What You Can Do About It – Michael Rubino | 1041 https://www.youtube.com/watch?v=QD5RUcN8uds&t=2s • Improve Your Home Environment & Breathe Better – Michael Rubino | 1045 https://www.youtube.com/watch?v=gncPqFlRXho&t=2s Sponsors: Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide. Calroy | Head to https://calroy.com/dave for an exclusive discount.  Resources: Michael Rubino’s Website: https://www.themoldmedic.com Michael Rubino’s Instagram: https://www.instagram.com/mold_medics/Michael Rubino’s Book: https://www.themoldmedic.com/books Michael Rubino’s Company: https://www.allamericanrestoration.com Ryan Blaser’s Website: https://www.testmyhome.com Ryan Blaser’s Instagram: https://www.instagram.com/testmyhome/Ryan Blaser’s Blog: https://www.testmyhome.com/blog Matteo Franceschetti’s Website: https://www.eightsleep.com Matteo Franceschetti’s Instagram: https://www.instagram.com/matteofranceschetti Eight Sleep Instagram: https://www.instagram.com/eightsleepDave’s Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com Own an Upgrade Labs: https://ownanupgradelabs.com Timestamps and Highlights: 00:00 Introduction: The Hidden Dangers in Your Home 00:02 Air Quality and Mold: The Silent Threat 00:40 Furniture Choices for Better Air Quality 01:51 Cleaning and Maintenance Tips 03:00 The Impact of Environmental Toxins 04:04 Formaldehyde and VOCs: Invisible Enemies 07:36 Energy Efficiency vs. Health 11:14 HVAC Systems and Air Filters 21:57 DIY Dust Testing and Home Lab Kits 29:02 Top Indoor Pollutants and Final Thoughts 30:47 Identifying Mold in Your Home 31:46 Health Impacts of Mold Exposure 32:18 Dangers of Air Fresheners and Fragrances 33:23 Improving Indoor Air Quality 35:59 Gas vs. Electric Stoves 37:07 Lighting and Its Effects on Health 40:57 Managing Humidity and Mold in Humid Climates 43:17 Carbon Monoxide: The Silent Killer 46:26 Dealing with VOCs in Your Home 50:38 Importance of Regular Cleaning 52:26 Noise Pollution and Its Impact 53:41 Advanced Sleep Tracking Technology 59:04 The Future of Consumer and Medical Devices  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if you could control your brain’s performance and stress levels with just a few simple hacks? In this episode callback, Dave Asprey sits down with Dr. Andrew Huberman, a renowned neuroscientist from Stanford University, to unlock the secrets of how your brain really works—and how you can train it for enhanced cognitive power and stress resilience. From rewiring your brain’s fear response to mastering your level of alertness, Dr. Huberman reveals groundbreaking discoveries that could change the way you approach your mental and emotional well-being. Diving deep into neuroscience, they cover how visual stimuli can modulate stress, the role of autonomic arousal in cognitive performance, and even how brain-machine interfaces may soon push human potential beyond its current limits. You’ll learn why certain visual and sensory techniques can calm or excite your brain, and how to train your brain to handle high-stress situations with ease. Plus, find out how Dr. Huberman is working on curing blindness with VR technology—offering a glimpse into the future of human augmentation. Sponsors:  Apollo Neuro | Head to https://apolloneuro.com/DaveAsprey to save 15% on an Apollo wearable.Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.Resources: Dr. Andrew Huberman’s Stanford Profile: https://profiles.stanford.edu/andrew-huberman Huberman Lab Podcast: https://hubermanlab.com/podcast Follow Dr. Andrew Huberman on Instagram: https://www.instagram.com/hubermanlab Dave’s Linktree: linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’: daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/    Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/  Supplements by Dave Asprey: https://shopsuppgradelabs.com/  Own an Upgrade Labs: https://ownanupgradelabs.com/ Timestamps and Highlights:   • 00:00 — Introduction and Cool Fact of the Day • 00:07 — Understanding Anxiety Through Brain Activity • 02:07 — Meet Dr. Andrew Huberman • 03:33 — The Five Components of Life Experience • 05:29 — Autonomic Arousal and Cognitive Performance • 08:00 — Visual Stimuli and Stress Management • 10:22 — Exploring Fear and Courage in Mice • 15:17 — Human Applications and VR Experiments • 23:10 — The Role of Vision in Autonomic Arousal • 29:38 — Bridging Neuroscience and Wellness • 30:43 — Curing Blindness: A Personal Mission • 34:50 — VR Goggles and Visual Stimulation • 35:12 — The Power of Virtual Art Galleries • 35:58 — Exploring Neuroplasticity in Adults • 38:31 — Potential and Risks of VR Technology • 40:27 — Human Augmentation and Neuroscience • 43:22 — Brain-Machine Interfaces and Non-Invasive Techniques • 45:47 — The Evolution of Biohacking • 52:03 — Personal Biohacking Journeys • 56:34 — Longevity and Life Extension • 59:28 — Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Get ready to upgrade your cardiovascular health in a way you’ve never heard of before. Dave Asprey sits down with Dr. Michael Twyman, a pioneering biohacking cardiologist who blends cutting-edge functional medicine with conventional wisdom to help you avoid heart attacks and strokes. If you think cardiovascular disease is inevitable, think again. Dr. Twyman reveals the hidden mechanisms behind heart disease, starting with the misunderstood role of plaque in your arteries and the essential yet underappreciated glycocalyx—a slippery gel-like coating that could be the key to preventing arterial damage. From there, it’s all about prevention, prevention, prevention. Want to know how simple lifestyle tweaks can significantly reduce your risk of cardiovascular events? We’ve got the biohacks—grounding, sunlight exposure, cold plunges, and more—laid out for you in a step-by-step, easy-to-apply format. Dr. Twyman breaks down the crucial role of circadian biology and how aligning your body clock with natural light cycles can help protect your heart. Plus, learn why grounding might just be the ultimate, free anti-inflammatory tool you’ve been missing. This episode isn’t just about tips and tricks—it’s a complete roadmap to understanding and optimizing your heart health. Dave and Dr. Twyman get into the nitty-gritty of lab tests you should be asking for, why exercise is only part of the solution, and how the current medical insurance model fails to protect your cardiovascular future. Don’t miss out on these life-saving insights that are rooted in both ancient wisdom and modern science.  Sponsors:  Viome | Go to https://viome.com/dave to save $110 on the Full Body Intelligence Test. fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Resources: Calroy Health Sciences: https://calroy.com/ Dr. Michael Twyman’s Website: https://www.apollocardiology.com/ Follow Dr. Michael Twyman on Instagram: https://www.instagram.com/drtwyman Dave’s Linktree: linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’: daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/    Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/  Supplements by Dave Asprey: https://shopsuppgradelabs.com/  Own an Upgrade Labs: https://ownanupgradelabs.com/ Timestamps and Highlights: • 00:00 — Introduction to Cardiovascular Health • 01:22 — Meet Dr. Michael Twyman • 05:57 — Understanding Heart Attacks • 08:09 — The Role of Glycocalyx in Cardiovascular Health • 15:17 — Lifestyle Changes for Cardiovascular Health • 24:32 — Exercise and Cardiovascular Health • 27:58 — Effective VO2 Max Strategies • 28:12 — Patient Exercise Goals and Time Management • 29:12 — Thyroid and Cardiovascular Health • 32:49 — Circadian Biology and Heart Disease • 33:57 — Sunlight, Grounding, and Seasonal Health • 38:49 — The Role of Statins in Cardiovascular Health • 43:16 — Key Labs for Cardiovascular Risk Assessment • 50:33 — Insurance and Preventative Health • 54:35 — Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Are you sleeping enough—or just enough to get by? In this episode of The Human Upgrade, Dave Asprey dives into the global sleep crisis and reveals why mastering your sleep is the most important biohack you can do for your health, performance, and longevity. This episode is your ultimate guide to transforming your rest and, by extension, your life. First, sleep scientist Matthew Walker breaks down how sleep deprivation has become a global epidemic, slashing up to 20% of our sleep in the past century. He unpacks the dangers of too little sleep, including its direct link to increased mortality rates and cognitive decline, and discusses the optimal sleep duration for both quantity and quality. Next, Peter Martone shifts the conversation to sleep posture and environment. He shares simple yet effective techniques for optimizing your sleep position to maximize deep, restorative rest. Learn how a small change in your pillow or bed setup can lead to dramatic improvements in your sleep quality and overall health. Finally, Dan Gartenberg dives into the world of sleep biohacking. He reveals groundbreaking research on how sound waves can enhance your deep sleep and how controlling light exposure can unlock better rest. From sleep-tracking tech to environmental optimizations, Dan provides actionable tips to help you take your sleep game to the next level. By the end of this episode, you’ll walk away with expert-backed strategies, biohacking secrets, and sleep science insights that will completely transform the way you sleep—and live. Check out the Full Episodes here:  - Sleep is the Boss of You – Matthew Walker, Ph D | 616 https://www.youtube.com/watch?v=cxmtBy0YQjs - Change Your Body Position To Get Better Sleep with Dr. Peter Martone | 819 https://www.youtube.com/watch?v=RKhA3iclRK0 - Sleep Need & Sleep Age Find Out Yours – Dan Gartenberg | 583 https://www.youtube.com/watch?v=XbxB67M-s2A Sponsors: Leela Quantum | Head to https://leelaq.com/DAVE for 10% off. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order.  Resources: Matthew Walker’s Website: https://www.sleepdiplomat.com Matthew Walker’s Instagram: https://www.instagram.com/drmattwalker/ Matthew Walker’s Podcast: https://themattwalkerpodcast.buzzsprout.com Matthew Walker’s Book: https://www.amazon.com/Why-We-Sleep-Unlocking-Dreams/dp/1501144316 Peter Martone’s Website: https://www.necknest.com Peter Martone’s Instagram: https://www.instagram.com/peter.martone/ Peter Martone’s YouTube Channel: https://www.youtube.com/user/drpetemartone Peter Martone’s Facebook Group: https://www.facebook.com/groups/necknest Dan Gartenberg’s Website: https://www.sonicsleepcoach.com Dan Gartenberg’s Instagram: https://www.instagram.com/drdansgarden/ Dan Gartenberg’s App: https://www.sonicsleepcoach.com Dan Gartenberg’s TED Talk: https://www.ted.com/speakers/dan_gartenberg Dave’s Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com Own an Upgrade Labs: https://ownanupgradelabs.com  Timestamps and Highlights: 00:00 Introduction: The ROI on Sleep 00:24 Global Sleep Loss Epidemic 01:43 Sleep Duration and Mortality Risk 06:23 The Importance of REM Sleep 12:47 Optimizing Sleep Quality 17:37 Technological Interventions for Better Sleep 19:02 Temperature Regulation and Sleep 21:03 Light's Impact on Sleep 24:44 Personal Sleep Hacks and Experiments 33:40 Understanding Lymphatic and Glymphatic Drainage 34:42 Debunking Side Sleeping Myths 35:30 The Importance of Cervical Alignment 37:07 Improving Sleep Quality with Neck Nest 38:00 Audience Questions: TMJ and Sleep 41:07 The Impact of Food and Temperature on Sleep 45:28 Enhancing Sleep with Sound and Technology 01:01:08 The Role of Cortisol in Sleep Quality See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dave Asprey is joined again by glutathione expert Nayan Patel to explore the transformative effects of this “master antioxidant” glutaryl. From skin health and detoxification to energy production and mitochondrial function, glutathione plays a critical role in overall wellness. Nayan shares his cutting-edge research on topical glutathione delivery systems that are more effective than IV treatments and help combat oxidative stress. The conversation touches on innovative applications of glutathione for skin lightening (yes, including the surprising trend of butthole bleaching), the impact of environmental toxins, and how to optimize glutathione levels to support longevity and performance. Whether you’re battling oxidative stress, looking to rejuvenate your skin, or just curious about how glutathione can boost your health, this episode has something for everyone. Visit https://aurowellness.com/ and use code Dave10 to get 10% off your order!  Resources: Nayan Patel’s Bio: https://www.a4m.com/nayan-patel.html Auro Wellness Instagram: https://www.instagram.com/aurowellness Glutaryl Skin Products: https://aurowellness.com/ Dave’s Linktree: https://linktr.ee/daveasprey   Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com    Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/  Own an Upgrade Labs: https://ownanupgradelabs.com  Timestamps and Highlights: 00:00 Introduction to an Unusual Topic 00:36 The Human Upgrade with Dave Asprey 00:52 The Importance of Glutathione 01:34 Introducing Nayan Patel and Glutaryl 02:05 Benefits of Topical Glutathione 02:36 Personal Health Journey and Skin Care 03:21 Deep Dive into Glutathione Technology 08:13 Glutathione and Skin Health 10:00 Vitamin C and Glutathione 17:54 Diet, Oxidative Stress, and Glutathione 20:26 Detox Reactions and Glutathione 24:26 Using Glutathione for Recovery 26:54 The Cost of Biohacking 27:26 Gene Therapy and Glutathione 28:20 Affordable Alternatives to IV Treatments 29:06 Endocrine Hormones and Glutathione 34:02 Sun Exposure and Skin Care 38:00 Morning and Night Skincare Routines 40:33 Telomeres and Anti-Aging 44:55 Hair Loss and Glutathione 47:12 Conclusion and Final Thoughts   See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this transformative episode of The Human Upgrade, three of the world’s foremost experts on sexual wellness—Kim Anami, Susan Bratton, and Emily Morse—explore the depths of sexual mastery, pleasure, and performance. This discussion uncovers the often-overlooked power of sexual energy as a source of personal growth, healing, and vitality. Whether you’re looking to enhance your pleasure, improve your intimate relationships, or explore new dimensions of intimacy, this episode serves as your ultimate guide to unlocking the full potential of your sexual energy. Kim Anami delves into the profound ways sexual energy can be harnessed for personal transformation, teaching how to access life-changing orgasms and deeper intimacy. Susan Bratton brings her expertise to sexual biohacking and the latest technology that can enhance physical pleasure and performance. Emily Morse focuses on breaking down societal taboos around sex and providing actionable advice for better communication and connection with partners. Together, these experts deliver a comprehensive guide to sexual empowerment, sharing actionable techniques that elevate both physical pleasure and emotional connection. By the end of this episode, you’ll have the knowledge to transform your sex life into a source of greater health, energy, and overall well-being. Check out the Full Episodes here:  -The Science of Sex: Longevity, Pleasure & Performance - Susan Bratton | 1087 https://youtu.be/3idAK1D85cs -Unleash Your Sexual Potential: Date Nights, Fantasies, and Healing in 'Smart Sex' with Emily Morse https://youtu.be/WyzdS8H__yM - From Holistic Sex to Vaginal Kung Fu with Kim Anami https://youtu.be/zLs3OgwiDSU Sponsors: Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Pendulum | Go to https://pendulumlife.com/ and use code Asprey20 for your first month of GLP-1 or any Pendulum formula. Resources: Kim Anami’s Website: https://kimanami.com Kim Anami’s Instagram: @KimAnami Kim Anami’s Podcast: Orgasmic Enlightenment Kim Anami’s Courses: The Well-F**ked Woman Susan Bratton’s Website: https://susanbratton.com Susan Bratton’s Instagram: @SusanBratton Susan Bratton’s Book: Sexual Soulmates Susan Bratton’s Supplements: The 20 Store Emily Morse’s Website: https://sexwithemily.com Emily Morse’s Instagram: @SexWithEmily Emily Morse’s Podcast: Sex with Emily Emily Morse’s Book: Hot Sex: Over 200 Things You Can Try Tonight Dave’s Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com Own an Upgrade Labs: https://ownanupgradelabs.com  Timestamps and Highlights: 00:00 Introduction to Life-Changing Experiences 00:32 Understanding Orgasm Challenges 01:33 Impact of Medications on Sexual Health 02:12 Physical Health and Sexual Arousal 02:56 The Dark Side of Birth Control Pills 06:30 Men's Role in Birth Control Decisions 07:10 Communication in Sexual Relationships 13:25 The Importance of Feeling Safe 16:37 Techniques for Deep Connection 21:26 The Orgasm Gap and Sexual Performance 27:02 Harnessing Sexual Energy for Transformation 33:31 Breathing Techniques for Sexual Energy 34:00 Vaginal vs. Clitoral Orgasms 34:36 The Power of Cervical Orgasms 34:58 Sexual Reflexology and Spiritual Rebirth 35:27 Personal Experiences with Orgasms 36:08 The Anami Guarantee 38:09 Spirituality and Sexuality 40:12 Historical Suppression of Sexual Energy 41:48 Impact of Fifty Shades of Grey 44:22 Pandemic Effects on Sexuality 46:01 Sex Toys and Their Benefits 49:26 Penis Pumps and Male Enhancement 01:01:40 The Importance of Nocturnal Erections See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, Dave Asprey sits down with Clint Ober, the pioneer of grounding and earthing technology. Together, they explore the profound effects of reconnecting your body with the Earth’s natural energy through grounding, revealing how this practice can reduce inflammation, optimize mitochondrial function, and enhance overall well-being. Clint explains how he discovered the power of grounding during his career in the cable television industry and how it led him to study its benefits on human health. From studies showing improved cortisol levels and reduced inflammation to anecdotes about athletes using grounding for recovery, this episode delves into the science and personal experiences that highlight the effectiveness of earthing. Sponsors:  Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources: Earthing Website: earthing.com Follow Clint Ober on Instagram: @clintober Dave’s Linktree: linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’: daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/    Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/  Supplements by Dave Asprey: https://shopsuppgradelabs.com/  Own an Upgrade Labs: https://ownanupgradelabs.com/ Timestamps and Highlights:  • 00:00:00 — Tour de France • 00:00:30 — Dave Asprey’s Personal Journey with Grounding • 00:02:00 — Welcome Clint Ober: The Grounding Pioneer • 00:04:17 — Clint Ober’s Background and Discovery of Grounding • 00:06:53 — The First Experiments and Observations • 00:18:24 — Initial Studies and Surprising Results • 00:25:54 — Collaboration with Dr. Stephen Sinatra • 00:33:17 — Public Perception and Challenges • 00:35:42 — The Organic Growth of Grounding • 00:36:18 — David Wolfe and the Raw Vegan Movement • 00:36:57 — The Impact of Grounding on Health • 00:38:03 — Grounding in Sports: The Tour de France Story • 00:40:12 — Scientific Evidence and Studies on Grounding • 00:45:37 — Historical Practices of Grounding • 00:48:47 — Grounding Products and Practical Tips • 00:54:51 — The Future of Grounding Technology  • 01:05:36 — Final Thoughts and Encouragement See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, we dive deep into the mystifying world of quantum energy with guest Philipp Samor von Holtzendorff-Fehling, founder of Leela Quantum Tech and Quantum Upgrade. Together with host Dave Asprey, Philipp unpacks the potential of harnessing quantum energy to enhance human performance, heal the body, and unlock higher consciousness.Philipp discusses how quantum energy has always existed and how modern technology now allows us to access and concentrate it like never before. From personal anecdotes involving quantum blocks to the exploration of biofields and how they influence everything from athletic performance to wound healing, this episode is packed with eye-opening insights.Dave shares his initial skepticism and eventual acceptance of quantum technology after experiencing the benefits firsthand. The conversation covers a range of fascinating topics including energy healing, distributed consciousness, quantum entanglement, and the ethics of working with energy fields. Plus, real-world examples like the flower experiment showcase the tangible effects of quantum energy in everyday life.Sponsors: Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order.Fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE.Resources:Leela Quantum Tech: leelaq.comQuantum Upgrade: quantumupgrade.ioFollow Philipp on Instagram: https://www.instagram.com/philipp_vhf/ Dave’s Linktree: linktr.ee/daveaspreyDave Asprey’s Book ‘Smarter Not Harder’: daveasprey.com/booksDave's Linktree: https://linktr.ee/daveasprey  Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/  Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/Timestamps and Highlights:• 00:00:00 — Ancient Alien Technology?• 00:00:39 — Show Intro• 00:01:33 — Dave’s Experience with Quantum Technology• 00:04:45 — Introducing Philip Samor von Holtzendorf-Fehling• 00:05:38 — Quantum Technology Explained• 00:06:35 — Personal Experiences with Quantum Devices• 00:11:00 — Understanding Biofields and Energy Healing• 00:15:21 — Philip’s Journey to Quantum Technology• 00:21:22 — Quantum Energy in Sports Performance• 00:26:21 — Exploring Quantum Fields in Cells• 00:27:11 — Quantum Blocks and Distributed Consciousness• 00:27:53 — Quantum Energy and Flower Experiment• 00:28:36 — Leela Quantum and Quantum Upgrade Explained• 00:29:44 — Quantum Entanglement and Location• 00:32:00 — Energy Fields and Geomagnetics• 00:33:53 — Ethics and Integrity in Quantum Energy• 00:36:19 — Scientific Evidence and Blood Studies• 00:40:00 — Wound Healing and ATP Production• 00:41:47 — Autism Clinical Trials and Brainwave Analysis• 00:48:40 — Intuition and Frequency Selection• 00:54:17 — Final Thoughts and Call to ActionSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this "Best of Nutrition" episode, 3 experts in nutrition share powerful insights on improving your health and performance through optimal eating habits. Listen in as Dr. Mark Hyman, Andrea Bemis, and Shawn Stevenson provide practical tips on boosting energy, improving digestion, and choosing nutrient-dense foods to help you feel your best. Dr. Mark Hyman, a leading expert in functional medicine, dives deep into the importance of nutrient-dense foods and traditional cooking oils like ghee and olive oil. He shares his insights on how these healthy fats support brain health, metabolism, and overall well-being, especially in children. Learn how simple dietary changes can have a significant impact on health. Shawn Stevenson, best-selling author and host of The Model Health Show, breaks down the role of nutrition in optimizing performance and mental clarity. He highlights the science behind choosing the right foods to fuel your body and mind, offering practical tips for enhancing energy and building a sustainable healthy lifestyle. Andrea Bemis, author and advocate for regenerative agriculture, explores how the way we source and grow our food directly affects nutrient quality. She discusses the importance of eating seasonally and locally, providing valuable insights on how to incorporate farm-fresh foods into everyday meals to nourish your body and support the environment. CHECK OUT THE FULL EPISODES NOW! Dr. Mark Hyman: https://youtu.be/TcEgBrfT8LI Shawn Stevenson: https://youtu.be/J2Tq_2Bawig Andrea Bemis: https://youtu.be/bFCASBNah0w Sponsors:  Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide.  ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources: Mark Hyman’s Website: https://drhyman.com Mark Hyman’s Instagram: @drmarkhyman Andrea Bemis’s Website: https://dishingupthedirt.com Andrea Bemis’s Instagram: @andreabemis Shawn Stevenson’s Website: https://themodelhealthshow.com Shawn Stevenson’s Instagram: @shawnmodel Dave's Linktree: https://linktr.ee/daveasprey     Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books     Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/    Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/  Supplements by Dave Asprey: https://shopsuppgradelabs.com/  Own an Upgrade Labs: https://ownanupgradelabs.com/  Timestamps and Highlights: 00:00:00 — Introduction by Dave Asprey 00:01:58 — Dr. Mark Hyman on Cooking Oils 00:04:04 — Feeding Kids Nutrient-Dense Meals 00:07:16 — Efficient Cooking and Eating with Kids 00:11:27 — Introducing New Foods to Children 00:12:56 — Listening to Kids’ Intuitive Eating Signals 00:14:28 — Salt in Children's Diets 00:22:32 — Regenerative Agriculture and Nutrient Density 00:31:28 — Finding High-Quality Foods See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, gut health experts Dr. Steven Gundry, Dr. Edward Group, and Hannah Kleinfeld share groundbreaking insights into the gut microbiome, detoxification, and the impact of fermented foods on digestion. Discover how caring for your gut can enhance your energy, brain health, and immunity. Check out the Full Episodes here:  Dr. Steven Gundry: https://youtu.be/SpO6k9Ofh2E Hannah Kleinfeld: https://youtu.be/zFKHJIX8vtM  Dr. Edward Group: https://youtu.be/GV2KnL0wW9M Sponsors: Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources: Dr. Steven Gundry's Book, Gut Check: https://drgundry.com Dr. Steven Gundry's Podcast: https://drgundry.com/the-dr-gundry-podcast/ Dr. Steven Gundry’s Instagram: @DrGundry Dr. Steven Gundry's Facebook: Dr. Steven Gundry Global Healing by Dr. Edward Group: https://globalhealing.com Global Healing Instagram: @globalhealingofficial Dr. Edward Group Instagram: @drgroupofficial Omni-Biotic: https://omnibioticlife.com Instagram: @omnibioticlife Dave's Linktree: https://linktr.ee/daveasprey     Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books     Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/    Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/  Supplements by Dave Asprey: https://shopsuppgradelabs.com/  Own an Upgrade Labs: https://ownanupgradelabs.com/  Timestamps and Highlights: 00:01:00 — Introduction to Gut Health and Parasites with Dr. Steven Gundry 00:06:00 — Fermented Foods & Gut Health with Hannah Kleinfeld 00:12:30 — Probiotics and Detox with Dr. Edward Group 00:18:00 — Practical Steps for a Healthier Gut See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, Dave Asprey and Dr. Heather Sandison discuss actionable strategies for optimizing brain health and longevity. Dr. Sandison explains how lifestyle changes, including diet, oral hygiene, and sleep, can help prevent cognitive decline. She also shares insights into the Marama Experience, her revolutionary approach to memory recovery and brain health. Sponsors:  Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.  Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. Resources: Dr. Sandison’s Website: www.drheathersandison.com Reversing Alzheimer’s Book: https://reversingalzheimersbook.com Dr. Sandison’s Facebook: https://www.facebook.com/HeatherSandisonND Dr. Heather Sandison’s Instagram: https://www.instagram.com/dr.heathersandison/ Dr. Sandison’s TikTok: https://www.tiktok.com/@drheathersandison Dave's Linktree: https://linktr.ee/daveasprey     Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books     Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/    Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/  Supplements by Dave Asprey: https://shopsuppgradelabs.com/  Own an Upgrade Labs: https://ownanupgradelabs.com/  Timestamps and Highlights: 00:00:01 – Introduction by Dave Asprey 00:02:30 – The Role of Diet in Brain Health 00:07:00 – The Importance of Oral Health in Brain Function 00:12:00 – How Sleep Impacts Cognitive Health 00:17:30 – Key Strategies for Optimizing Cognitive Function 00:22:00 – The Marama Experience: Memory Care to Memory Recovery 00:30:00 – Steps for Protecting Brain Health Over Time See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, Dave Asprey talks to Chris Fields, Chief Science Officer at Applied Food Sciences, about the game-changing nootropic AmaTea® Max. They discuss how this natural extract of guayusa delivers long-lasting energy and mental clarity, backed by science and sustainable practices. Learn how AmaTea® Max is revolutionizing cognitive performance, especially for athletes and gamers. Resources: Where to buy products with AmaTea® organic guayusa: https://appliedfoods.com/wheretobuyAmaTea® Max Website: https://appliedfoods.com/amateamax AmaTea® Max Instagram: https://www.instagram.com/appliedfoodsciences Dave's Linktree: https://linktr.ee/daveasprey     Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books     Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/    Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/  Supplements by Dave Asprey: https://shopsuppgradelabs.com/  Own an Upgrade Labs: https://ownanupgradelabs.com/  Timestamps and Highlights: 00:01 – Why Caffeine is a Super-Powerful Nootropic 04:00 – The Science of Guayusa and AmaTea® Max 07:00 – Cultural Roots and Sustainable Sourcing 11:30 – The Cognitive Benefits of AmaTea® Max 16:20 – How AmaTea® Max Differs from Traditional Caffeine Sources 20:00 – Applications in Gaming and Sports 25:00 – Sustainability and Social Impact See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, Dave Asprey welcomes Dr. Jamil Zaki, a professor of psychology at Stanford University and the director of the Stanford Social Neuroscience Lab. Dr. Zaki discusses the critical intersection between empathy, cynicism, and hope, exploring the impacts of negativity bias, cynicism in modern society, and how we can rewire our brains to become more hopeful. Drawing from his latest research and new book, Hope for Cynics, Dr. Zaki shares profound insights on human goodness, how we can challenge our biases, and the practices that can help us foster a more positive outlook on the world. Sponsors: Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide.  ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order.   Resources: Jamil Zaki’s website: jamil-zaki.com Jamil Zaki's New Book: Hope for Cynics: The Surprising Science of Human Goodness Dave's Linktree: https://linktr.ee/daveasprey     Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books     Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/    Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/  Supplements by Dave Asprey: https://shopsuppgradelabs.com/  Own an Upgrade Labs: https://ownanupgradelabs.com/  Timestamps and Highlights: 00:00:01 – Introduction by Dave Asprey 00:02:00 – Dr. Zaki on Cynicism and Empathy 00:05:30 – The Science Behind Empathy and Human Goodness 00:10:00 – The Impact of Negativity Bias on Decision-Making 00:15:00 – How to Overcome Cynicism Through Skepticism 00:20:30 – Practices to Foster Empathy and Optimism 00:30:00 – Understanding Cynicism in the Digital Age 00:35:00 – Building Hope in Relationships and Society See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this special Asprey Archive episode from 2023, we talk to Shaahin Cheyene.Today’s guest is nothing short of a modern-day Willy Wonka for Generation X. He built a billion-dollar ecstasy business in the '90s and did not end up behind bars. That's a story you've got to hear. Shaahin Cheyene, not only dabbled in the wild world of herbal ecstasy but also managed to stay out of trouble despite being investigated by seven attorney generals. And get this, he wasn't even 18 when he pulled off these daring feats.Shaahin's story doesn't stop there. Since those days, he's become an Amazon expert, successfully selling nootropics and a variety of other products on the platform. He's also a filmmaker and author of the book, “Billion: How I Became the King of the Thrill Pill Cult.” From Fleeing Iran at the age of five to being homeless and living out of his car, Shaahin's journey is nothing short of remarkable. It's safe to say he's one of the most interesting individuals I've had the pleasure of interviewing. We dive into Shaahin's captivating journey, exploring his transformation from a young criminal to a thriving entrepreneur. You’ll also learn about what went into his groundbreaking herbal ecstasy formula and how he managed to get his business off the ground. Along the way, we discuss the challenges of navigating the bureaucracy of big government, the importance of seeking help when needed, and the valuable lessons Shaahin learned from building and eventually exiting his herbal ecstasy empire. We also delve into how he managed to run a nine-figure company selling on Amazon, the mindset benefits of Brazilian jiu-jitsu training, the power of curating ideas, and how you can strategically leverage podcasts as an entrepreneur. Join us on a ride you won't want to miss.(01:47) How Shaahin Became the King of the Thrill Pill Cult(07:36) Formulating Herbal Ecstasy & Building a Million-Dollar Business(16:34) Navigating the Bureaucracy of Big Government(28:04) Pro Tip for Entrepreneurs: Why It’s Important To Ask for Help(32:09) What Cheyene Learned From Building & Exiting His Business(37:29) What To Do When You Make Your First Million(39:21) Scaling a 9-Figure Company Selling on Amazon(45:05) Lessons From Martial Arts & Our Bets on Musk vs Zuckerberg(54:03) The Tactical Advantage of Podcasting & Being a Curator of Ideas(01:03:30) Media Training 101SponsorsLMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/dave.Leela Quantum | Head to https://leelaq.com/DAVE for 10% off. ResourcesWebsite: shaahincheyenne.comPodcastCola: podcastcola.comInstagram: @shaahincheyenePodcast: Business Story of the WeekLinkedIn: Shaahin CheyeneSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, vision expert Claudia Muehlenweg and strength coach Dave Mark Bell join Dave Asprey to explore the intersection of natural vision improvement and physical performance. Claudia shares her expertise in the Bates Method and techniques like palming, which help restore clarity and reduce eye strain. Dave Mark Bell highlights how physical training and focus can enhance not only strength but also vision, showing the deep connection between the body and mind. Check out the Full Episodes here: Claudia Muehlenweg: https://youtu.be/SpO6k9Ofh2EDave Mark Bell: https://youtu.be/GV2KnL0wW9MSponsors: Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide. Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: Naturally Clear Vision | Claudia Muehlenweg: https://www.youtube.com/@HolisticVisionCoach Dave Mark Bell’s Instagram: @marksmellybell Dave's Linktree: https://linktr.ee/daveasprey     Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books     Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/    Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/  Supplements by Dave Asprey: https://shopsuppgradelabs.com/  Own an Upgrade Labs: https://ownanupgradelabs.com/  Timestamps and Highlights: 00:00:01 — Introduction by Dave Asprey 00:01:02 — Claudia Muehlenweg’s Introduction 00:03:30 — Palming and Its Benefits 00:06:15 — The Role of Eye Movement in Vision Health 00:09:25 — Dave Mark Bell’s Approach to Physical Training and Vision 00:12:45 — Sunlight and Vision 00:18:35 — Vision Improvement Techniques for Daily Life 00:22:50 — Vision and Fitness Synergy with Dave Mark Bell See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this enlightening episode of The Human Upgrade, Dave Asprey is joined by polymath and visionary Robert Edward Grant. Known for his groundbreaking work in fields ranging from mathematics and cryptography to art and consciousness, Robert shares insights into how his diverse expertise has shaped his understanding of the interconnectedness of science, art, and spirituality. The conversation delves into ancient knowledge, biohacking for personal evolution, and the deeper mysteries of consciousness, exploring how tapping into these realms can lead to profound innovation and a higher state of being. Sponsors: OneSkin | Go to https://oneskin.co/ and use code ASPREY15 for 15% off your purchase.  Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.  Resources: Robert Grant’s Website: robertedwardgrant.com  Follow Robert Grant on Instagram: @robertedwardgrant Dave's Linktree: https://linktr.ee/daveasprey     Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books     Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/    Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/  Supplements by Dave Asprey: https://shopsuppgradelabs.com/  Own an Upgrade Labs: https://ownanupgradelabs.com/ Timestamps and Highlights: 00:00:01 — Introduction by Dave Asprey 00:02:05 — What It Means to Be a Polymath 00:05:34 — Innovation Through Cross-Disciplinary Thinking 00:08:26 — Consciousness and Psychedelics 00:13:22 — The Limits of Knowledge and Enlightenment 00:28:35 — The Path to Enlightenment 00:30:29 — The Benefits of Fasting for Mental and Physical Clarity 00:34:52 — The Power of Cold Therapy 00:38:23 — Overcoming Challenges in Biohacking See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, Dave Asprey is joined by Dr. Stephanie Venn-Watson, a veterinary epidemiologist and co-founder of Seraphina Therapeutics, to explore the groundbreaking discovery of C15, also known as Pentadecanoic acid. This episode uncovers how Dr. Venn-Watson's work with aging dolphins in the U.S. Navy led to the surprising revelation that C15 is an essential fatty acid, marking the first discovery of its kind in nearly a century. Through extensive research, C15 has shown powerful benefits for longevity, reducing inflammation, and promoting cellular health, which can help prevent chronic conditions like metabolic syndrome and heart disease. Dr. Venn-Watson explains the science behind C15, its natural sources—such as grass-fed dairy and certain types of fish—and why it’s often missing from modern low-fat diets. She also dives into the clinical studies that reveal how C15 can stabilize cell membranes, reduce oxidative stress, and improve metabolic function. The episode emphasizes the importance of this ‘new’ fat for anyone seeking to optimize their health, whether through diet or supplementation. Sponsors: Fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Resources: Dr. Stephanie Venn-Watson’s Company: Seraphina Therapeutics Dr. Stephanie Venn-Watson’s Instagram: @fatty15 Learn More About C15: discoverC15.com Dave's Linktree: https://linktr.ee/daveasprey     Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books     Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/    Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/  Supplements by Dave Asprey: https://shopsuppgradelabs.com/  Own an Upgrade Labs: https://ownanupgradelabs.com/ Timestamps and Highlights: 00:00:01 — Introduction by Dave Asprey 00:01:02 — Dr. Stephanie Venn-Watson’s Introduction 00:03:15 — The Discovery of C15 00:05:56 — C15 in Fish and Dairy 00:08:03 — C15’s Role in Longevity and Cellular Health 00:12:35 — Clinical Studies and Health Benefits 00:20:12 — C15 and Vegan Diets See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, four experts—Dr. Molly Maloof, Aggie Lal, Dr. Justin Lehmiller, and Dr. Mary Claire Haver—discuss personalized biohacking strategies for women, focusing on hormonal balance, mitochondrial health, sexual wellness, and optimizing energy through cycle syncing and stress management. Dr. Molly Maloof, a health optimization expert and author, delves into the unique challenges women face in biohacking, focusing on mitochondrial health and the impact of hormonal fluctuations on energy and performance. She shares personalized strategies for optimizing health through nutrition, exercise, and stress management tailored to a woman’s biology. Aggie Lal, a certified health coach and biohacker, discusses the importance of balancing masculine and feminine energy for optimal health. She provides insights into cycle syncing, exercise, and lifestyle adjustments that empower women to harness their energy and enhance overall well-being. Dr. Justin Lehmiller, a social psychologist and researcher at the Kinsey Institute, explores the intersections of sexual health and biohacking, offering evidence-based insights into how sexual wellness impacts overall health. He discusses practical strategies for improving sexual relationships and boosting emotional and physical vitality through scientific research on sex and desire. Dr. Mary Claire Haver, an obstetrician and founder of The Galveston Diet, focuses on the challenges women face during menopause and midlife, providing expert guidance on nutrition and hormone balancing. She shares her evidence-based approach to supporting women through hormonal changes and optimizing health through targeted lifestyle interventions. Check out the Full Episodes here:  Molly Maloof, MD https://www.youtube.com/watch?v=m9MkjHmQEfI&t=1577s Aggie Lal https://www.youtube.com/watch?v=2kizZSZT-As Justin Lehmiller, Ph.D. https://youtu.be/RS4VP07rKL0  Mary Claire Haver, MD https://www.youtube.com/watch?v=Ka-4YZUMQVE  Timestamps and Highlights: 00:00:01 — Introduction by Dave Asprey 00:02:08 — Molly Maloof’s Journey 00:10:46 — Aggie Discusses Balancing Masculine and Feminine Energy 00:18:57 — Biohacking Your Menstrual Cycle 00:35:50 — Mitochondrial Health and Stress Management  Sponsors: ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order.  Resources: Dr. Molly Maloof’s Website: https://drmolly.co Dr. Molly Maloof’s Instagram: @drmolly.co Aggie Lal’s “Biohack Like a Woman”: https://biohackingbestie.com/products/biohack-like-a-woman Biohacking Bestie: https://biohackingbestie.com/ Instagram: https://www.instagram.com/aggie/ Instagram: https://www.instagram.com/biohackingbestie/ TikTok: https://www.tiktok.com/@biohackingbestie Biohacking Bestie Podcast: https://biohackingbestie.com/pages/biohacking-bestie-podcast Dr. Justin Lehmiller’s Website: https://justinlehmiller.com Dr. Justin Lehmiller’s Instagram: @justinlehmiller Dr. Mary Claire Haver’s Website: https://galvestondiet.com Dr. Mary Claire Haver’s Instagram: @drmaryclaire Dave’s Linktree: linktr.ee/daveasprey Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/  Supplements by Dave Asprey: https://shopsuppgradelabs.com/  Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this insightful episode of The Human Upgrade, Dave Asprey sits down with Dr. Mary Newport, a renowned expert in lipid metabolism and brain health, to discuss the critical role of fats in preventing Alzheimer's disease and promoting cognitive longevity. Dr. Newport, author of the book Clearly Keto for Healthy Brain Aging and Alzheimer’s Prevention, shares her deep knowledge of how different fats impact brain function, the benefits of ketogenic diets, and the connection between infections like herpes and Alzheimer’s disease. Learn about her personal journey caring for her husband, who was diagnosed with early-onset Alzheimer’s, and how ketogenic interventions, including coconut oil and MCT oil, led to significant improvements in his cognitive health. Tune in to learn more about the role of diet, ketones, and brain health, and how to make strategic food choices to maintain cognitive resilience as you age. Timestamps: 00:00:00 — Opening 00:01:07 — Introduction to Dr. Mary Newport and her work 00:02:29 — Clearly Keto: Overview of her new book 00:04:44 — Her husband’s Alzheimer’s journey 00:07:48 — Ketones and brain health 00:12:09 — Keto diets for brain function 00:24:00 — Insulin resistance and Alzheimer’s 00:44:00 — Alzheimer's research insights 01:01:18 — Final thoughts Sponsors: Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order.  Pendulum | Go to https://pendulumlife.com/ and use code Asprey20 for your first month of GLP-1 or any Pendulum formula.  Resources: Website: http://coconutketones.com  Facebook: Coconut Oil Helps Alzheimer’s, Dementia, ALS, MS https://www.facebook.com/CoconutOilandAlzheimers/  Twitter: https://twitter.com/marynewportmd  LinkedIn: https://www.linkedin.com/in/mary-newport-md-226b3479/ Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://dangercoffee.com/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

On this special Upgrade Spotlight episode of The Human Upgrade, you'll dive into the cutting-edge world of ketones and their profound impact on brain function and overall health with Michael Brandt, CEO and Co-founder of HVMN. Discover how Ketone IQ can fuel your cognitive abilities, enhance physical performance, and support your body's resilience under stress. Michael unpacks the science behind ketones, explaining how they improve mitochondrial efficiency, support fasting, and aid in recovery. He also shares innovative strategies to incorporate Ketone IQ into your daily routine, whether you're looking to boost your meditation practice, enhance athletic performance, or simply improve your metabolic flexibility. Tune in to uncover the latest advancements in ketone technology and learn how you can leverage them to optimize your health and performance. Timestamps: 00:00:00 — Opening 00:01:07 — Introduction to Ketones and the Episode's Focus 00:03:08 — Michael Brandt's Background 00:04:43 — Ketone IQ and Venture Capital 00:05:38 — The Science of Ketosis and Ketone IQ 00:10:27 — Ketone IQ vs. Other Ketone Supplements 00:19:24 — Ketones and Mitochondrial Function 00:22:02 — Practical Benefits of Ketone IQ 00:23:34 — Entrepreneurial Journey and Innovation 00:30:10 — Ketone IQ and Fasting 00:37:05 — Ketones, Cognition, and Special Operations 00:44:00 — Ketones and Brain Function 00:52:22 — Personal Fasting and Biohacking Experiences 00:57:05 — Ketone IQ in Sports and Olympics 01:01:18 — Ketone IQ and the Future of Biohacking 01:06:35 — Final Thoughts and Recommendations Sponsors: HVMN | Go to ketone.com/dave for 30% off your first subscription of Ketone IQ. Resources: Ketone IQ: ketone.com/dave for 30% off subscription HVMN: Follow on Instagram: @KetoneIQ Michael Brandt’s Instagram: @michaeldbrandt Dave's Linktree: https://linktr.ee/daveasprey Follow Dave on Instagram: @Dave.Asprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: [https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: ourupgradecollective.com Danger Coffee by Dave Asprey: @dangercoffeeofficial Supplements by Dave Asprey: shopsuppgradelabs.com Own an Upgrade Labs: ownanupgradelabs.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this special "Best Of" episode of The Human Upgrade, four leading experts delve into the hidden dangers of mold, environmental toxins, and their profound effects on your health and well-being. Brian Karr, an indoor environmental consultant and co-founder of We Inspect, discusses the impact of mold exposure and offers practical tips for detecting and remediating mold in your home. He highlights how mold can manifest in various symptoms and affect people differently. Michael Rubino, President of HomeCleanse, explores environmental toxins in our homes, highlighting the dangers of pollutants like formaldehyde and VOCs. Learn essential tips for maintaining clean air and creating a healthier living space to protect your health from mold and other toxins. Tune in for expert strategies on identifying and mitigating these risks. Dr. Francesca LeBlanc, a functional medicine expert, explains the connection between mold exposure, hormone imbalances, and weight gain. She shares insights on detoxing from mold and the importance of addressing underlying issues like estrogen dominance and candida. Dr. Neil Nathan, an environmental medicine expert and author of Toxic, explores the effects of mold toxicity on the immune system and provides strategies for protecting yourself from mold and other environmental toxins. CHECK OUT THE FULL EPISODES NOW! Brian Karr: https://www.youtube.com/watch?v=P_4UcEAZCEw&t=1760s Michael Rubino: https://www.youtube.com/watch?v=JFWcuWrEy60&t=73s Dr. Francesca LeBlanc: https://www.youtube.com/watch?v=_k3NGd-yfg8&t=1741s Dr. Neil Nathan: https://www.youtube.com/watch?v=eOEoQswppNc Timestamps: 00:00:01 - Introduction by Dave Asprey 00:02:08 - Dave's Personal Battle with Toxic Mold 00:03:06 - Understanding Mold with Brian Karr 00:10:40 - History of We Inspect and Mold Detection 00:18:57 - Mold in Rental Properties and Legal Challenges 00:23:17 - Practical Steps for Reducing Mold Exposure 00:35:50 - Dr. Francesca LeBlanc on Mold, Weight Gain, and Hormonal Imbalances 00:55:10 - The Role of Candida and Diet in Mold Recovery 01:00:22 - Dr. Neil Nathan on Mold Toxicity and Immune System Impact  Sponsors: Puori | Visit Puori.com/DAVE and use the promo code DAVE for 20% storewide. ZBiotics | Go to Zbiotics.com/Dave for 15% off your first order Resources: Brian Karr’s Company: https://yesweinspect.com/ Brian Karr’s Instagram: @moldfinders Michael Rubino’s Linktree: https://linkin.bio/themichaelrubino/ Michael Rubino’s Instagram: @TheMichaelRubino Dr. Francesca LeBlanc’s Linktree: https://stan.store/drfrancescaleblanc Dr. LeBlanc’s Instagram: @drfrancescaleblanc Dr. Neil Nathan’s Books: https://neilnathanmd.com/about-me/ Dr. Neil Nathan’s website: https://neilnathanmd.com/ Dave’s Linktree: linktr.ee/daveasprey Follow Dave on Instagram: @Dave.Asprey Danger Coffee by Dave Asprey: Danger Coffee Instagram Supplements by Dave Asprey: Shop Upgrade Labs Own an Upgrade Labs: Own an Upgrade LabsSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, recorded live from Costa Rica, Dave Asprey sits down with Dr. Vince from the Regenerative Medicine Institute (RMI) to delve into the groundbreaking world of regenerative medicine. Dr. Vince shares his expertise on how advanced therapies, including stem cell treatments and personalized regenerative protocols, are paving the way for enhanced longevity and optimal health. Listeners will gain insight into how these cutting-edge treatments can address chronic pain, accelerate recovery, and combat aging at the cellular level. Dr. Vince also emphasizes the importance of personalized medicine, where treatments are tailored to each individual's unique biological needs. This episode is a must-listen for anyone interested in exploring the future of regenerative health and how to apply these innovations to improve their own healthspan and lifespan. Timestamps: 00:00:01 — Opening 00:02:44 — Introduction to Dr. Vincent Giampapa 00:05:50 — Dr. Giampapa’s Morning Cognitive Enhancement Protocol 00:09:23 — The Role of Brain Imaging in Personalized Medicine 00:13:09 — Stem Cell Therapy: The New Frontier in Longevity 00:19:29 — The Importance of Banking Stem Cells for Future Use 00:32:35 — Groundbreaking Anti-Aging Treatments at RMI 00:42:43 — Focused Ultrasound and Reprogramming the Hypothalamus 00:50:16 — The Role of Peptides in Muscle Growth and Cognitive Function 01:06:42 — How to Get Started with Longevity Treatments 01:12:24 — Ethical Considerations in Longevity Science 01:23:47 — Future of Gene Therapy and Mitochondrial Enhancement 01:30:02 — Final Thoughts and Closing Remarks Sponsors: Quantum Upgrade | Go to QuantumUpgrade.io/Dave for a free trial Timeline Nutrition | Head to TimelineNutrition.com/Dave to get 10% off your first order. Resources: Inquire about RMI Treatment: https://daveasprey.com/clock/Learn more about RMI: https://rmi.life/Dave Follow Dr. Giampapa on Instagram: @drgiampapa Dr. Giampapa’s website: https://drgiampapa.org/ Dave's Linktree: linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: ourupgradecollective.com Danger Coffee by Dave Asprey: @dangercoffeeofficial Supplements by Dave Asprey: shopsuppgradelabs.com Own an Upgrade Labs: ownanupgradelabs.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this special "Best Of" episode of The Human Upgrade, four leading experts share their insights on skincare, skin health, and cutting-edge techniques to enhance your appearance and overall well-being. Rachel Varga, a Board-Certified Aesthetic Nurse Specialist and recognized expert in skin rejuvenation, discusses the importance of biohacking for maintaining vibrant, healthy skin. She highlights key strategies, including air and water purification, regular detoxification, and the careful selection of skincare products free from harmful chemicals. Dr. Anthony Youn, a Board-Certified Plastic Surgeon and bestselling author, reveals the most common skincare mistakes made by both men and women. He provides actionable advice on avoiding harmful practices like over-exfoliation and improper sunscreen use, while also emphasizing the critical role of diet in achieving glowing, youthful skin. Dr. Nayan Patel, a global expert in glutathione research and author of The Glutathione Revolution, explains the essential role of glutathione in detoxification and cellular health. He shares insights into the most effective methods for glutathione supplementation and the latest advancements in personalized health testing. Dr. Rob Whitfield, a Board-Certified Plastic Surgeon and founder of the Austin area's premier aesthetic clinic, explores the latest non-invasive procedures for skin tightening and rejuvenation. He compares various technologies, including IPL, lasers, and SoftWave, and discusses the innovative “No Cut Facelift” technique for achieving long-lasting results without surgery. Tune in to this episode to learn expert strategies for optimizing your skincare routine and enhancing your skin’s health and appearance from top professionals in their field. CHECK OUT THE FULL EPISODES NOW! Rachel Varga: https://www.youtube.com/watch?v=J9b7i6nOwpI&t=1899s Dr. Anthony Youn: https://www.youtube.com/watch?v=gGcpW0_KAIU&t=2588s Dr. Nayan Patel: https://www.youtube.com/watch?v=H2j23OdO-1E Dr. Rob Whitfield: https://www.youtube.com/watch?v=leFjhLWQBqo  Timestamps: 00:00:01 - Introduction by Dave Asprey 00:00:10 - The Importance of Skin Health and Biohacking Techniques 00:05:03 - Harmful Ingredients in Skincare Products 00:09:00 - Core Biohacking Strategies for Healthy Skin 00:14:10 - Men’s Skincare Mistakes: Bar Soap and Over-Exfoliation 00:18:50 - Understanding Sunscreen: Chemical vs. Physical 00:23:35 - Women’s Skincare Pitfalls: Overuse of Products and Procedures 00:27:50 - The Role of Glutathione in Detoxification and Health 00:32:45 - Innovations in Glutathione Testing and Personalized Health 00:36:30 - Non-Invasive Skin Tightening with SoftWave 00:42:15 - Comparing Skin Rejuvenation Techniques: IPL, Lasers, and More Sponsors: Fatty15 | Go to Fatty15.com and save an extra $15 when you subscribe with code DAVE. LMNT | Free LMNT Sample Pack with any drink mix purchase by going to DrinkLMNT.com/Dave  Resources: Rachel Varga’s Linktree: https://linktr.ee/rachelvargaofficial Follow Rachel on Instagram: @RachelVargaOfficial Dr. Anthony Youn’s Linktree: https://taplink.cc/tonyyounmd Dr. Anthony Youn’s Instagram: @TonyYounMD Auro Wellness on Instagram: @AuroWellness Dr. Rob Whitfield’s Linktree: https://linktr.ee/drrobertwhitfield Follow Dr. Rob on Instagram: @breastimplantillnessexpert Dave’s Linktree: linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: Link to book Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: ourupgradecollective.com Danger Coffee by Dave Asprey: Danger Coffee Instagram Supplements by Dave Asprey: shopsuppgradelabs.com Own an Upgrade Labs: ownanupgradelabs.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, Dr. Manoj Doss, a neuroscientist at the University of Texas at Austin Dell Medical School, explores the fascinating intersection of psychedelics, memory, and cognitive enhancement. Drawing from his extensive research, Dr. Doss dives into how psychoactive substances like THC, ketamine, and psychedelics can alter memory formation, consolidation, and retrieval. He challenges the conventional understanding of memory by revealing how these substances might disrupt traditional memory processes while potentially opening new pathways for learning and cognition. You'll discover how different drugs impact your brain's ability to encode and recall information, the surprising effects of psychedelics on semantic and episodic memory, and the role of the hippocampus in shaping our personal narratives. Dr. Doss also delves into the potential benefits and risks of cognitive enhancers like nicotine and modafinil, offering insights into their effects on memory and brain function. Dr. Doss provides a nuanced perspective on the malleability of memory, the ethical implications of memory manipulation, and the complex relationship between trauma, memory, and psychedelics. This episode is essential for anyone interested in the cutting-edge science of memory, the therapeutic potential of psychedelics, and the quest to enhance cognitive performance. Timestamps: 00:00:01 — Opening 00:01:39 — Introduction to Dr. Manoj Doss 00:03:20 — The Impact of Psychedelics on Memory 00:05:50 — The Predictive Processing Framework and Mind Models 00:13:22 — Alcohol and Retrograde Facilitation: Enhancing Memory Post-Study 00:19:00 — Differences Between Episodic and Semantic Memory 00:22:57 — The Role of the Hippocampus in Memory Formation 00:32:35 — Exercise, BDNF, and Memory Enhancement 00:42:29 — The Complex Relationship Between Psychedelics and Neurogenesis 00:52:16 — The Fallibility of Memory and False Memory Formation 01:09:04 — The Influence of Nicotine, Modafinil, and Other Cognitive Enhancers 01:30:34 — Closing Remarks Sponsors: ARMRA | Go to TryARMRA.com and use the code DAVE to get 15% off your first order. Leela Quantum | Head to LeelaQ.com/Dave for 10% off. Resources: Follow Dr. Manoj Doss on Twitter Dave's Linktree: https://linktr.ee/daveasprey Follow Dave on Instagram: @Dave.Asprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, Dr. Christy Sutton delves into the intricate relationship between iron, zinc, copper, and other essential minerals that play a crucial role in longevity and overall health. Drawing from her book, The Iron Curse, Dr. Sutton shares insights into how mineral imbalances can lead to conditions like iron overload, anemia, and other health issues, and how these imbalances affect the body’s ability to function optimally. You'll learn about the significance of monitoring and managing your mineral levels, the impact of iron on cognitive function and aging, and the genetic factors that influence mineral absorption. Dr. Sutton also discusses the importance of personalized nutrition and supplementation in maintaining optimal health and preventing disease. Dr. Sutton provides practical advice on how to recognize symptoms of mineral imbalances, the importance of regular lab testing, and the role of diet and lifestyle in managing these conditions. This episode is a must-listen for anyone interested in taking control of their health and longevity by understanding the foundational role of minerals in the body. Timestamps: 00:00:01 — Opening 00:02:44 — Introduction to Dr. Christy Sutton 00:05:50 — Iron Levels and Longevity 00:13:09 — Recognizing the Symptoms of High Iron 00:19:29 — Iron Levels in Children and the Risk of Misdiagnosis 00:32:35 — Managing High Iron through Diet and Supplementation 00:42:43 — Key Labs to Monitor for Iron and Mineral Levels 00:50:16 — The Role of Copper in Iron Absorption 01:06:42 — Closing Remarks Sponsors: Calroy | Head to Calroy.com/Dave for an exclusive discount. Viome | Go to Viome.com/Dave to save $110 on the Full Body Intelligence Test.  Resources: Buy Dr. Christy’s book: The Iron Curse Dr. Christy Sutton's Linktree: https://linktr.ee/drchristysutton Follow Dr. Christy on Instagram: https://www.instagram.com/drchristysutton/ Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Follow Dave on Instagram: @Dave.Asprey  Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/  Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, renowned opera singer Renée Fleming explores the powerful connection between music, neuroscience, and longevity. Renée shares her journey with stage fright and somatic pain, revealing how she overcame these challenges to achieve greatness in her field. You'll learn about the impact of music on the brain, its role in enhancing cognitive function, and its potential to delay dementia. Renée discusses functional MRI studies, the benefits of group singing, and the integration of music into healthcare. Renée also shares practical tips on maintaining vocal health and immunity, the healing power of nature, and the importance of artistic practices in childhood development. This episode is for anyone who wants to understand the transformative power of music and its potential to enhance brain health, emotional well-being, and overall longevity. Timestamps: (00:00:00) Opening (00:01:56) Renée Fleming's Journey with Music and Neuroscience (00:05:25) The Experience of Stage Fright: Physical and Mental Aspects (00:12:24) The Power of Imagining Singing (00:14:18) Impact of Music on the Brain: A Broader Perspective (00:16:32) Breathwork and Singing's Benefits on the Nervous System (00:18:33) Music’s Role in Delaying Dementia (00:26:26) The Benefits of Group Singing (00:29:59) The Synchronization of Brainwaves and Heart Rates (00:31:08) The Impact of Artistic Practices on Children (00:36:12) The Importance of Nourishing the Soul with the Arts (00:42:47) The Intersection of Psychedelics and Music (00:50:23) Advances in Sound Therapy for Health (00:54:35) Renée’s Personal Practices and Preferences (00:56:10) Closing Thoughts and Reflections Sponsors Timeline | Go to Timeline.com/Dave to get 10% off your first order. Zbiotics | Head to Zbiotics.com/dave for 15% off your first order. Resources Renee Fleming Linktree: https://linktr.ee/reneeflemingmusic Follow Renee Fleming on Instagram: @ReneeFlemingMusic Buy Ms. Fleming’s new book “Music and Mind” now! Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Follow Dave on Instagram: @Dave.Asprey  Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/  Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, Dr. Tracy Gapin, a board-certified urologist, men's health expert, and founder of the GAPIN Institute, discusses the critical role of testosterone in health. He addresses the alarming decline in testosterone levels globally, the symptoms of low testosterone, and its impact on male behavior. You'll gain insights into natural methods to boost testosterone, the challenges of maintaining optimal levels, and the pros and cons of Testosterone Replacement Therapy (TRT). Dr. Tracy explains the role of estrogen and DHT in health and highlights the effects of testosterone on brain function, motivation, and cardiovascular health. You’ll learn about the adverse effects of environmental toxins on testosterone, effective delivery methods, and the importance of personalized treatment plans. Dr. Gapin also covers practical tips for reducing exposure to environmental toxins, balancing work, life, and health, and the significance of sleep and recovery.Timestamps: 00:00:00 - Introduction to Dr. Tracy Gapin and Testosterone Discussion 00:02:00 - The Importance of Measuring Free Testosterone 00:03:43 - Symptoms and Impact of Low Testosterone 00:06:23 - Natural Ways to Boost Testosterone 00:09:59 - Testosterone Replacement Therapy (TRT) Options 00:15:18 - Health Benefits and Brain Function of Optimized Testosterone Levels 00:17:48 - Environmental Toxins and Declining Fertility Rates 00:25:57 - Effective Testosterone Delivery Methods 00:29:47 - Overtraining and Its Impact on Hormones 00:42:51 - Microplastics and Their Impact on Health 00:53:40 - Comprehensive Health Assessments at the GAPIN Institute 01:02:57 - Balancing Work, Life, and Health 01:13:26 - Practical Tips for Avoiding Environmental Toxins 01:27:26 - The Importance of Sleep and Recovery 01:38:36 - Conclusion and Final Thoughts Sponsors:  Our Place | Head to FromOurPlace.com and use the code DAVE for 10% off your order. Fatty 15 | Go to Fatty15.com and save an extra $15 when you subscribe with the code DAVE15.  Resources: Check out the Gapin Institute: https://gapininstitute.com/upgradeGapin Institute Linktree: https://linktr.ee/gapininstitute Follow Dr. Tracy on Instagram: @DrTracyGapin Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Follow Dave on Instagram: @Dave.Asprey  Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/  Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this special episode of The Human Upgrade, you will gain insights from four experts on brain health, memory, attention, and cognitive enhancement. Dr. Daniel Amen, a renowned psychiatrist and brain health expert, discusses the importance of daily practices for brain and mental health. He shares strategies to improve brain function and prevent cognitive decline. Jim Kwik, a brain coach and memory expert, talks about physical and mental exercises that boost brain performance. He offers tips on how to improve reading, memory, and focus, and highlights the benefits of both fiction and nonfiction reading. Dr. Adam Gazzaley, a neuroscientist and professor, explains the difference between top-down and bottom-up attention. He introduces Endeavor Rx, a video game approved by the FDA to improve attention in children with ADHD and shares how it can benefit adults as well. Dr. Patrick Porter, an expert in brain fitness and neurogenesis, discusses the BrainTap technology. He explains how it can enhance cognitive function, reduce stress, and improve sleep through guided meditation and light therapy. Tune in to this episode to learn practical tips and expert advice on optimizing brain health, improving memory, and enhancing attention for better cognitive performance. CHECK OUT THE FULL EPISODES NOW! Dr. Daniel Amen: https://youtu.be/ri7-Ou6VvSI Jim Kwik: https://youtu.be/QCt2XHJkt2Y Dr. Adam Gazzaley: https://youtu.be/H9QT7bKFgmM Dr. Patrick Porter: https://youtu.be/o8B4XrueQlc Timestamps: 00:00:07 - Introduction by Dave Asprey 00:00:10 - Dr. Daniel Amen on Brain Health Practices 00:10:04 - Jim Kwik on Physical and Mental Exercise 00:12:28 - Jim Kwik on Reading and Brain Exercises 00:18:22 - Jim Kwik on Sleep and Productivity 00:30:26 - Dr. Adam Gazzaley on Top-Down vs Bottom-Up Attention 00:40:02 - Dr. Adam Gazzaley on Endeavor Rx and Attention Improvement 00:46:51 - Dr. Patrick Porter on Neurogenesis and Brain Fitness 00:58:51 - Dr. Patrick Porter on BrainTap and Cognitive Enhancement Sponsors: Fatty15 | Go to Fatty15.com and save an extra 15$ when you subscribe with code DAVE15. Our Place | Go to FromOurPlace.com and use code DAVE for 10% off your order. Resources: Dr. Daneil Amen’s Website: https://danielamenmd.com/ Dr. Daniel Amen’s Instagram: @Doc_Amen Jim Kwik’s Instagram: @JimKwik Jim Kwik’s Linktree: https://linktr.ee/kwiklearning Dr. Adam Gazzaley’s Instagram: @adamgazzaley Dr. Adam Gazzaley’s website: https://gazzaley.com/ BrainTap’s Instagram: @BrainTapTech BrainTap’s Linktree: https://linktr.ee/braintap Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Follow Dave on Instagram: @Dave.Asprey  Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/  Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

On this special Upgrade Spotlight episode of The Human Upgrade, you'll explore the science of NAD and its vital role in your cellular health with Dr. Nichola Conlon from Nuchido Laboratories. Learn how NAD supports energy production, cellular repair, and longevity. Dr. Conlon breaks down the latest research on NAD, explaining why levels decline with age and how to naturally boost them without expensive and uncomfortable IV treatments. Dr. Conlon breaks down innovative ways to enhance your NAD levels, reduce inflammation, and improve overall health and shares practical tips on maintaining high NAD levels through diet, lifestyle changes, and supplementation. You’ll understand how these strategies can combat fatigue, brain fog, and aging symptoms, offering benefits for both physical and cognitive performance. Tune in to uncover the latest advancements in NAD research and how you can apply them to enhance your cellular health and well-being. Timestamps: 00:00:00 — 1: Opening 00:01:07 — 2: Introduction to NAD and Dr. Nichola Conlon 00:01:46 — 3: Understanding NAD and Its Functions 00:02:23 — 4: The Challenges of Boosting NAD Levels 00:05:31 — 5: The Science Behind NAD Decline and Aging 00:09:15 — 6: Clinical Studies and Evidence 00:14:35 — 7: Practical Benefits of Boosting NAD 00:19:17 — 8: Addressing Inflammation and Glycation 00:26:32 — 10: Big Pharma vs. Supplement Approach 00:30:10 — 11: Enhancing Bioavailability of Supplements 00:33:45 — 12: Impact on Chronic Conditions 00:37:05 — 13: Addressing Autoimmunity and Inflammation 00:44:00 — 15: Final Thoughts and Recommendations Sponsors: Nuchido | Go to Nuchido.com/Upgrade, or use code Upgrade10, for a 10% discount!  Resources: Nuchido.com/Upgrade, or use code Upgrade10, for a 10% discount! Follow Nuchido on Instagram: @Nuchido Nuchido’s Linktree: https://linkin.bio/nuchido/ Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Follow Dave on Instagram: @Dave.Asprey  Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/  Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this special episode of The Human Upgrade, you will gain insights from four fitness and health experts on understanding muscle, how to grow muscle, exercise effectively, and recover properly. Dr. Gabrielle Lyon, a functional medicine physician, emphasizes the critical role of skeletal muscle as an organ of longevity. She explains how muscle health impacts overall well-being and offers strategies to prevent age-related muscle loss. John Jaquish, the inventor of the X3 bar, discusses the benefits of variable resistance training. He shares his expertise on progressive overload and how data-driven training can enhance muscle growth and performance. Tony Horton, the creator of P90X, introduces the concept of muscle confusion. He explains how varying workout routines can prevent plateaus, reduce injuries, and keep your fitness journey exciting and effective. Magnus Lygdbäck, a celebrity trainer, provides tips on optimizing performance and recovery. He highlights the importance of structured habits, balanced nutrition, and recovery techniques like ice baths and isometric exercises to sustain high performance. Tune in to this episode to learn practical tips and expert advice on building muscle, improving exercise routines, and optimizing recovery for long-term health and fitness.  CHECK OUT THE FULL EPISODES NOW! Dr. Gabrielle Lyon: https://youtu.be/X3hkW0afys0  John Jaquish: https://youtu.be/6efQiP_rCLM  Tony Horton: https://youtu.be/BRSvTx8Ank4  Magnus Lygdbäck: https://youtu.be/9x3fvChVwyo  Timestamps: 00:00:00 — Opening 00:00:10 — Dr. Gabrielle Lyon on Skeletal Muscle Health 00:02:32 — Aging and Muscle 00:06:03 — Measuring Muscle Quality 00:09:15 — Genetic Potential 00:20:41 — John Jaquish on Variable Resistance Training 00:24:32 — Progressive Overload 00:27:37 — Neurological Adaptation 00:31:47 — Data-Driven Training 00:34:39 — One Meal a Day and Protein 00:44:15 — Tony Horton on Muscle Confusion 00:47:45 — Using Bands for Resistance 00:50:16 — Continuous Training 00:52:03 — Balancing Rest and Work 00:54:27 — Magnus Lygdbäck on Optimizing Performance 00:57:15 — Nutrition vs. Training 01:00:15 — Avoiding Perfectionism 01:02:48 — Pre-Performance Training 01:05:59 — Blood Flow Restriction  Sponsors: Calroy | Head over to Calroy.com/Dave for an exclusive discount LMNT | Get a free LMNT Sample Pack with any drink mix purchase by going to DrinkLMNT.com/Dave Resources: Dr. Gabrielle Lyon's Website: https://drgabriellelyon.com/ Dr. Gabrielle Lyon’s Instagram: @drgabriellelyon Order Dr. Gabrielle Lyon’s Book: Forever Strong John Jaquish's X3 Bar: https://www.jaquishbiomedical.com/ Dr. John Jaquish’s Instagram: @drjaquish Tony Horton's Programs: https://www.tonyhortonlife.com/ Tony Horton’s Instagram: @TonySHorton Magnus Lygdbäck’s Instagram: @magnuslygdback Magnus Lygdbäck's Training: https://www.magnusmethod.com/ Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Follow Dave on Instagram: @Dave.Asprey  Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/  Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, entrepreneur and philanthropist Naveen Jain discusses groundbreaking insights into the differences between oral and gut microbiomes and the impact of oral bacteria on overall health. You’ll learn why traditional mouthwash might be harmful and explore the Apollo Group's role in health mentoring and collaboration. Naveen shares his decade-long dedication to solving health issues and his approach to large-scale health problems. You’ll discover the relationship between oral microbiomes and digestion, the dangers of artificial sweeteners, and the importance of personalized nutrition. Naveen emphasizes the need for cycling low-carb and keto diets, and the risks of long-term adherence. He also highlights the significance of quality sleep, personalized exercise, and the impact of stress on microbiome health. Tune in for practical tips on maintaining a healthy microbiome and the importance of living with purpose for longevity. Timestamps: 00:00:00 — Introduction 00:01:02 — Oral Bacteria vs. Gut Bacteria 00:05:30 — Oral Microbiome and Digestion 00:09:00 — Low Carb and Keto Diet Misconceptions 00:12:23 — Red Meat and Microbiome 00:14:49 — Impact of Vegetables on Gut Health 00:23:02 — DNA vs. RNA in Health 00:30:56 — Debunking Blood Type Diets 00:31:57 — Lipopolysaccharides and Inflammation 00:40:07 — Importance of Oral Microbiome 00:50:28 — Practical Microbiome Health Tips 01:05:22 — Exercise and Microbiome 01:14:03 — Managing Stress for Health 01:22:18 — Purpose and Longevity Sponsors: Viome.com | Viome.com/Dave to save $110 on the Full Body Intelligence Test. Timeline Nutrition | Go to TimelineNutrition.com/Dave to get 10% off your first order. Leela Quantum | Visit LeelaQ.com/Dave for 10% off.  Resources:  Follow Naveen Jain on Instagram: @naveenjainceo Naveen Jain Linkedin: https://www.linkedin.com/in/naveenjainintelius/ Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Follow Dave on Instagram: @Dave.Asprey  Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/  Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, Dr. Robert Lufkin delves into the misconceptions in medical education and the vital importance of metabolic health. He discusses how outdated practices in medical training can negatively impact public health and shares insights on the critical role of personalized nutrition in enhancing metabolic health. Dr. Lufkin explores the connection between hormones and aging, highlighting new therapies that target hormonal balance. He also explains the paradigm shift in health, emphasizing the need to move beyond conventional wisdom and integrate new scientific research into everyday practice. You will learn about the latest advances in medical technology and how tech-driven interventions can extend HealthSpan. Dr. Lufkin also addresses the challenge of overcoming medical dogmas, stressing the importance of continuous learning and adaptation in the medical field. Tune in to discover emerging trends in personalized medicine, the future of healthcare, and practical strategies for improving health and longevity. This episode offers valuable knowledge and actionable advice for navigating the evolving landscape of modern medicine. Timestamps: (00:01:03) Introduction to Dr. Robert Lufkin (00:04:51) Misconceptions in Medical Education (00:12:27) Metabolic Health and Diet (00:16:32) Hormones and Aging (00:21:10) The Paradigm Shift in Health (00:29:17) The Role of Technology in Longevity (00:33:27) Extending Healthspan (00:40:54) Future of Medicine (01:00:32) Intermittent Fasting Benefits (01:10:15) The Role of Exercise in Longevity (01:20:12) Nutritional Supplements (01:30:18) Advancements in Anti-Aging Therapies (01:45:22) Closing Thoughts Sponsors: Neurohacker | Go to Neurohacker.com and use code Dave for 15% off. Quantum Upgrade | Head to QuantumUpgrade.IO/Dave for a free trial. Resources:  Dr. Robert Lufkin’s new book “The Sensitive Patient's Healing Guide” is out now! Learn more about Dr. Robert Lufkin’s work: RobertLufkinMD.com Follow Dr. Lufkin on Instagram: @robertlufkinmd Dr. Lufkin’s Linktree: https://linktr.ee/robertlufkinmd Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Follow Dave on Instagram: @Dave.Asprey  Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/  Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, Dr. Peter Ballerstedt, a leading expert in ruminant animal agriculture, discusses the essential role of ruminant animals in sustainable farming. You'll learn about the critical importance of animals like cows and sheep in maintaining soil health, supporting ecosystems, and providing high-quality nutrition. You’ll also learn about the myths surrounding livestock emissions and how regenerative farming practices benefit both the environment and human health. Dr. Ballerstedt explains the complexities of modern agriculture, emphasizing the importance of metabolic health and the significant impact of dietary choices on global food security. You'll gain insights into the health benefits of animal protein, crucial for preventing malnutrition and supporting overall well-being, and how integrating crop and livestock systems can enhance food production and sustainability. Tune in for valuable knowledge and practical advice on improving health and supporting sustainable agriculture through the inclusion of ruminant animals.  Timestamps: (00:01:03) What are Ruminant Animals? (00:03:27) The Importance of Ruminant Animals in Agriculture (00:05:09) The Environmental Impact of Ruminant Animals (00:17:24) Addressing Common Misconceptions (00:35:31) Sustainable Food Systems and Global Food Security (00:40:53) The Health Benefits of Animal Protein (00:57:15) The Importance of Metabolic Health Sponsors ARMRA | Go to TryARMRA.com and use code DAVE for 15% off your first order. Resources Follow Peter Ballerstedt on Instagram: @GrassBased Twitter: @GrassBased Peter’s Substack: https://ruminati.substack.com/ Peter’s blog: https://grassbasedhealth.blogspot.com/ Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Follow Dave on Instagram: @Dave.Asprey  Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/  Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this special Asprey Archive episode of The Human Upgrade you’ll get tips about how to lead a brain healthy lifestyle and how to keep perspective along your own entrepreneurial journey. Activism, acting and entrepreneurship are wired into Patrick Schwarzenegger’s DNA. In this episode from 2022, he thoughtfully balances each passion through his work as an Alzheimer’s advocate, actor, investor and food founder. Patrick’s known for his trend-spotting abilities in the better-for-you food and beverage industry. He got into the fast-casual Blaze Pizza franchise when he was just a teen. That experience solidified his interest in health and wellness: “invest solely into entrepreneurs and companies that were providing Americans with the healthier alternative." He’s now an active investor and advisor to numerous brands and helps founders scale their emerging businesses to the next level.His latest venture encourages brain health at every age and supports programs, research, and lifestyle choices designed to make your brain work better. Patrick co-founded a brain health food brand called “MOSH” with his mom, Maria Shriver, designed specifically to up-level your brain function.A journey with its share of mishaps, too: “We had so many things that went wrong and that was kind of the fun part was learning about that and finding ways to fix it. That's wanting to be an entrepreneur or that's embarking on that journey, you're going to have speed bumps. You can do as much homework as you can and want and try to perfect everything before you launch, but things come out of left field every single day.”He’s on the show to discuss entrepreneurship, how to invest, how to build brands, how to hire the right people and what’s possible for high-functioning brains at every age.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, Harry Massey joins the show to delve into the fascinating field of bioenergetics and its profound impact on health and healing. Discover how bioenergetics, the study of energy in living systems, can revolutionize your approach to wellness by enhancing the body's energy and control systems. Harry shares his journey from battling chronic fatigue syndrome to founding NES Health, where cutting-edge research and technology are used to enhance cellular function and resilience. You'll learn about the role of mitochondria, structured water, and light in boosting the body's energy and efficiency. The conversation also explores how bioenergetics can help reframe our understanding of health by integrating principles from physics, chemistry, and biology. You’ll also gain insights into the practical applications of bioenergetics, including NES Health's innovative voice scan technology that provides personalized health insights. Harry and Dave discuss the future of energy-based treatments and the importance of a strong energetic control system in maintaining the best health possible. Get ready to upgrade your understanding of health with actionable advice and scientific insights from two pioneers in the field! Timestamped Highlights (00:01:10) Harry Massey's background and journey through chronic fatigue syndrome. (00:02:16) Definition and principles of bioenergetics. (00:03:36) Charging the body’s energy and the role of structured water. (00:08:20) Efficiency of the energetic control system vs. chemical control system. (00:12:35) Impact of light and structured water on mitochondria. (00:18:26) Research on structured water and its effects on cellular health. (00:22:02) Increasing mitochondrial density and resilience. (00:26:15) Harry's personal health journey and the development of NES Health. (00:30:16) Comparison with homeopathy and the concept of information in water. (00:35:06) Overcoming skepticism and proving the effectiveness of bioenergetics. (00:42:46) Real-life examples of bioenergetic healing. (00:50:09) The impact of emotions on health and the importance of positive energy. (00:54:30) Enhancing resilience and protecting against negative influences. (01:01:09) Introduction to NES Health's voice scan technology. (01:05:53) Using voice analysis for health insights and personal coaching.  Sponsors NES Health: Go to neshealth.com/Dave for your free voice scan! Viome | Go to Viome.com/Dave to save $110 on the Full Body Intelligence Test. Apollo Neuro | Head to ApolloNeuro.com/DaveAsprey to save 15% on an Apollo wearable. Quantum Upgrade | Go to Quantum Upgrade.io/Dave for a free trial. Resources: NES Health: Go to neshealth.com/Dave for your free voice scan Energy4Life: energy4life.com Follow NES Health on Instagram: @NES.Health Get Tickets to the Zenergy Conference: zenergyconference.com Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Follow Dave on Instagram: @Dave.Asprey  Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/  Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, Dr. Neil Nathan joins to explore the intricate world of toxic mold, Lyme disease, and sensitivity-related illnesses. You'll discover the profound impact of these environmental toxins on your health and the innovative methods for diagnosing and treating them. Learn how mold and Lyme disease can disrupt your body's systems, and get practical strategies for protecting yourself from these hidden hazards. The discussion dives into the importance of the limbic and vagal systems, and how rebooting them can help manage sensitivity and promote healing. Dr. Nathan sheds light on the role of environmental pollution in exacerbating mold issues and offers tips for reducing your exposure to harmful toxins. You'll gain a deeper understanding of how to maintain resilience and enhance your health despite these challenges. Tune in to gain valuable insights and actionable advice on managing sensitivity and reclaiming your health from environmental toxins! Timestamps and Highlights: (00:00:01) Introduction (00:03:03) Mold Rage and Personality Changes (00:05:02) Understanding Mold Toxicity (00:09:04) Symptoms and Misdiagnosis (00:11:46) Environmental Factors and Increased Mold Toxicity (00:15:40) Practical Steps for Protection (00:19:35) Testing and Treating Mold Toxicity (00:25:26) Limbic and Vagal System Retraining (00:29:26) Personal Healing Practices (00:33:31) The Role of Intuition in Healing (00:39:31) Addressing Chronic Illness and Sensitivity (00:45:41) Emotional and Psychological Aspects of Healing (00:50:16) Conclusion Sponsors: Timeline Nutrition | Go to TimelineNutrition.com/Dave to get 10% off your first order. Beam Minerals | Go to BeamMinerals.com/Dave2024 for 20% off your first order Resources: Dr. Neil Nathan’s new book “The Sensitive Patient's Healing Guide” is out now! Learn more about Dr. Neil Nathan’s work: NeilNathanMD.com Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Follow Dave on Instagram: @Dave.Asprey  Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/  Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, Dr. John Gildea and David Roberts from BrocElite join to discuss the powerful benefits of sulforaphane and NRF2 activation. You'll hear about the science behind sulforaphane, a potent compound in broccoli, and how it can boost your health by protecting your cells and enhancing detoxification. Learn why eating broccoli and broccoli sprouts can be a game-changer for your diet and get practical tips on how to incorporate them into your meals. The discussion highlights the role of sulforaphane in supporting gut health and improving resilience to toxins. Dr. Gildea and David Roberts explain the importance of NRF2 activation in promoting longevity and better performance. You'll understand how these mechanisms work to keep your body functioning optimally and how you can leverage them for better health. Tune in to gain valuable insights and actionable advice on enhancing your health with sulforaphane and NRF2 activation!Timestamp Highlights: (00:00:00) Introduction: Benefits of sulforaphane and NRF2 activation. (00:01:04) Are Bodybuilders the Edgiest Biohackers? (00:02:10) Benefits of Broccoli and Sulforaphane (00:04:23) Isothiocyanates and Thyroid Function (00:10:57) Longevity and Performance Impacts of NRF2 (00:18:20) Resilience Against Toxins (00:24:57) Sulforaphane and Autism (00:31:08) Anti-Inflammatory Effects of Sulforaphane (00:40:52) Gut Health and Microbiome (00:45:58) Autophagy and Cellular Health (00:55:57) Dosage and Safety (01:02:00) Closing Thoughts Sponsors: Go to Mara-Labs.com/Dave and save up to 28% off your order. Our Place | Go to FromOurPlace.com and use the code DAVE for 10% off your order. ZBiotics | Go to Zbiotics.com/Dave for 15% off your first order. Resources: Go to Mara-Labs.com/Dave and save up to 28% off your order. Follow Mara Labs on Instagram: @themaralabs Twitter: @TheMaraLabs Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Follow Dave on Instagram: @Dave.Asprey  Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/  Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade - Max Lugavere, a journalist and filmmaker, joins to discuss his new documentary "Little Empty Boxes." Max shares his personal story of dealing with his mother's dementia, offering a unique and heartfelt perspective on this challenging condition. You’ll learn about the significant role diet and lifestyle play in keeping your brain healthy and how you can lower your risk of developing dementia through simple, everyday actions. Max also shares the latest research on dementia, shedding light on the science behind prevention and early intervention. He explains why it's crucial to start taking care of your brain health now, regardless of your age. Additionally, you’ll hear about the emotional impact of dementia on families and practical ways to support loved ones going through it. Tune in to gain valuable insights and actionable tips on how to protect your brain health and help others do the same. This episode is packed with practical advice that you can start applying today to make a real difference in your cognitive health and overall well-being. Timestamp Highlights: (00:01:04) Introduction: Max Lugavere’s personal connection to dementia. (00:04:51) The creation of "Little Empty Boxes" and its focus on dementia prevention. (00:12:27) The role of diet and lifestyle in dementia prevention. (00:16:32) Understanding the broad impact of dementia on families. (00:21:10) Insights into dementia research and the importance of early intervention. (00:29:17) The link between chronic disease and dementia. (00:33:27) Discussing the prevalence and risk factors of Alzheimer’s and other dementias. (00:38:34) The importance of being proactive about brain health. (00:40:54) Addressing myths and misconceptions about dementia. (00:50:18) Practical tips for reducing dementia risk. (00:55:10) Max's final thoughts and call to action.  Sponsors: ARMRA | Go to TryARMRA.com and use code DAVE to get 15% off your first order. Timeline | Try it out for yourself at TimelineNutrition.com/Dave and get 10% off your first order Resources: Little Empty Boxes Documentary: littleemptyboxes.com Max Lugavere’s Website: maxlugavere.com Instagram: @maxlugavere Twitter: @maxlugavere Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Follow Dave on Instagram: @Dave.Asprey  Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/  Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Get ready for a shocking episode of The Human Upgrade with our guest, Adam Gavine, recorded at the 10th Annual Biohacking Conference. You’ll learn how the revolutionary Wasabi Method is changing the game in shock wave therapy. You’ll also gain understanding on how this innovative approach addresses pain management, boosts longevity, and enhances overall health. The Wasabi Method stimulates tissue regeneration, reduces inflammation, and improves immune function. Adam shares practical applications for this therapy, including its benefits for reproductive health and reversing tissue aging. Whether you're a biohacker, health professional, or wellness enthusiast, this episode is packed with valuable insights and actionable information. Timestamp Highlights: (00:01:14) What is Shock Wave Therapy? (00:04:59) How Adam Got into Shock Wave Therapy (00:08:10) Launching the Wasabi Method (00:11:39) Treating Trigger Points and Knotted Muscles (00:16:46) Applications for Erectile Dysfunction (00:21:34) Reversing Tissue Stiffness and Calcification (00:25:35) Using Wasabi Method for Collagen Production (00:32:29) Cell Membrane Permeability and Nutrient Absorption (00:37:03) Systemic Anti-Inflammatory Effects (00:45:02) Increasing White Blood Cell Count (00:48:12) Scar Tissue Management and Healing (00:54:46) Empowering Individuals in Their Health Journey (01:00:01) Practical Applications and Business Models Sponsors: ARMRA | Head to TryARMRA.com and use code DAVE for 15% off Your first order BEAM Pets | Go to BeamMinearls.com/Dave2024 for 20% off your first order.  Resources The Wasabi Method| WasabiMethod.com Follow Wasabi Method on Instagram: @Wasabi_Method Follow Back To Function on Instagram: @back-to-functionBiohacking Conference: https://www.biohackingconference.com/ Dave's Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Follow Dave on Instagram: @Dave.Asprey  Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/  Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com/ Own an Upgrade Labs: https://ownanupgradelabs.com/  Studies referenced during the interview: Growth Factors & Angiogenesis Application of extracorporeal shock wave therapy in nervous system diseases - A review Extracorporeal shock wave therapy for treatment of vulvodynia: a prospective, randomized, double-blind, placebo-controlled study The Effect of Extracorporeal Shock Wave Therapy on Lower Limb Spasticity in Subacute Stroke Patients Efficacy of Extracorporeal Shockwave Therapy on Pain and Function in Myofascial Pain Syndrome IncRNA NEAT1-let 7b-P21 axis mediates the proliferation of neural stem cells cultured in vitro promoted by radial extracorporeal shock waves Effects of the extracorporeal shock wave therapy on the skin: an experimental study Molecular mechanism of action of low-intensity extracorporeal shockwave therapy for regenerating penile and peripheral nerves Comparison of shock wave therapy and US guided for shoulder injection therapy in patients with supraspinatus tendinitis Extracorporeal shock wave treatment in foot and ankle fracture non-unions — A review Treatment for Symptomatic Calcific Tendinopathy of the Shoulder: Ultrasound-Guided Needling Lavage and Extracorporeal Shock Wave Therapy vs Extracorporeal Shock Wave Therapy. A prospective observational study Effect of Low-Intensity Extracorporeal Shock Wave on the Treatment of Erectile Dysfunction: A Systematic Review and Meta-Analysis See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

On this special Upgrade Spotlight episode of The Human Upgrade, you'll learn about the critical connections between gut health, stress, and athletic performance with Hannah Kleinfeld from Omni Biotic. Find out how innovative probiotic formulations can enhance your overall well-being, reduce inflammation, and boost immune function. Hannah explains how gut health impacts both physical and mental performance, and shares practical tips for maintaining a healthy gut, personalizing your diet, and improving recovery.  Whether you're an athlete looking to enhance performance or someone managing everyday stress, this episode provides valuable insights and actionable strategies to support a high-performance lifestyle. Tune in to discover how you can leverage the latest in gut health science to enhance your life. Timestamps:(00:01:03) Introduction to the Topic (00:04:51) Importance of Gut Health in Stress and Athletic Performance (00:12:27) How Probiotics Enhance Performance and Recovery (00:16:32) Impact of Stress on the Gut and Immune System (00:21:10) Case Study: Antibiotics and Gut Recovery (00:29:17) Probiotic Innovations from Germany (00:33:27) Gut Health and Chronic Illness (00:38:34) Strategies for Maintaining Gut Health (00:40:54) Personalized Gut Health Plans (00:50:18) Dietary Choices and Gut Health (00:55:10) Research Insights and Future Directions Sponsors Omni-Biotic | Go to Omnibioticlife.com and use code Dave20 for 20% off your order. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Omni Biotic: omnibioticlife.com Instagram: @omnibioticlife Hannah’s LinkedIn: Hannah Kleinfeld YouTube: @Omni-Bioticlife1352See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Get ready for a fascinating episode with Darlene Teahen, a naturopath and researcher, who dives into the world of urine therapy. You'll learn about the science and history behind using urine for health benefits, including detoxifying the body, reducing inflammation, and boosting overall wellness. Darlene shares insights from her PhD research and offers practical advice on how to safely incorporate urine therapy into your routine. Darlene tackles societal taboos head-on, providing a thorough exploration of this ancient healing method backed by modern science. Whether you're curious about unconventional health practices or looking for new biohacking techniques, this episode delivers valuable information. This episode is packed with actionable insights on embracing unconventional methods, understanding the benefits of urine therapy, and integrating these practices into your daily life. Whether you're an avid biohacker or just exploring new health strategies, you'll find inspiration and practical advice here.Timestamps: 00:00:01 — Introduction 00:01:07 — History and Initial Reactions 00:02:14 — Scientific Backing 00:03:16 — Introduction of Guest: Darlene Teahen 00:03:30 — Personal Experiences and Skepticism 00:04:18 — Research and Evidence 00:05:49 — Practical Applications 00:06:53 — Societal and Medical Perspectives 00:07:40 — Personal and Professional Insights 00:08:03 — Emotional and Spiritual Aspects 00:08:58 — Advanced Techniques and Future Studies Sponsors: Zbiotics | Get 15% off now at Zbiotics.com/Dave LMNT | Go to DrinkLMNT.com/Dave for a free sample pack with any drink mix purchase Resources: Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Learn more about Darlene’s work: https://www.darleneteahen.ca/Donate to Darlene's research: Donations for research https://paypal.me/DTeahenFollow Darlene on Instagram: @vitalityexpert Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Get ready for an inspiring episode with Daymond John, the famous entrepreneur and Shark Tank star, recorded at the 10th Annual Biohacking Conference.  You’ll learn how Daymond turned his life around after a serious health scare and how he uses biohacking to stay on top of his game. You’ll also discover the importance of hearing health, why he gave up alcohol, and how he embraces life with a new sense of adventure. Daymond offers his unique approach to parenting and the values he instills in his daughters, like understanding the power of curiosity and how it drives success. Daymond believes in constant growth and never settling. This episode is packed with actionable insights on cutting out negativity, trusting your gut, and using storytelling in business. Whether you’re an aspiring entrepreneur or looking to improve your personal life, this episode offers valuable lessons and inspiration. Check out The Shark Health to learn more: https://thesharkhealth.com/Timestamps:[00:00:00] – Introduction by Daymond John[00:00:35] – Welcome and audience engagement: Daymond’s first experience at the event. [00:02:29] – Health scare: Daymond’s cancer diagnosis and the impact on his life. [00:07:14] – Embracing life: Daymond’s adventures and new appreciation for life. [00:10:03] – Raising daughters: Parenting and instilling values in his children. [00:15:38] – Never arriving: The continuous journey of personal and professional growth. [00:19:11] – Cutting out negativity: Removing toxic relationships for better health. [00:20:46] – Trust and intuition: How to identify trustworthy people in business. [00:23:19] – Entrepreneurs and storytelling: The power of storytelling in business success. [00:30:03] – Gut feeling: The importance of listening to your gut in decision making. [00:35:47] – Setting goals: The importance of goal setting and visualization. [00:40:50] – Empowering communities: Daymond’s mission with FUBU and beyond. [00:44:56] – Call to action: How to connect with Daymond and take advantage of resources. Sponsors Quantum Upgrade | Go to QuantumUpgrade.io/Dave for a 14-day free trial. Pendulum | Go to PendulumLife.com and use code Asprey20 for your first month of GLP-1 or any Pendulum formula.  Resources The Shark Health | https://thesharkhealth.com/ Follow Daymond John on Instagram: https://www.instagram.com/thesharkdaymond/  Daymond John’s Website: https://daymondjohn.com/ Dave's Linktree: https://linktr.ee/daveaspreyDave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/Supplements by Dave Asprey: https://shopsuppgradelabs.com/Own an Upgrade Labs: https://ownanupgradelabs.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode, Nicole Vignola, a neuroscientist with a BS in Neuroscience and a Master of Science in Organizational Psychology, explains how to rewire the brain for better decision-making and lasting change. You will learn about neuroplasticity, the science behind creating and undoing brain pathways, and practical strategies for forming new habits. Nicole shares the importance of visualization, taking strategic breaks, and focusing on strengths rather than weaknesses. She discusses the concept of mental currency and how to allocate energy effectively. The episode also covers how to manage negative thoughts, boost positive thinking, and the role of myelination in habit formation. Nicole explains how to use visualization paired with physical activity to reinforce new habits and prepare for setbacks. This episode provides actionable advice for anyone looking to improve mental health, enhance cognitive function, and create lasting positive changes in their life. Nicole’s new book, “Rewire: Break the Cycle, Alter Your Thoughts and Create Lasting Change (Your Neurotoolkit for Everyday Life)” is out now! Timestamps:(00:01:02) Introduction to Nicole Vignola and her work (00:01:44) The importance of affirmations and voice modulation (00:06:31) Fundamentals of neuroplasticity (00:09:42) The future of neuron regeneration (00:13:54) Habits, myelination, and cognitive energy (00:19:03) Mental currency and vigilance decrement (00:23:32) Trying harder vs. strategic rest (00:28:05) Morning vs. evening energy dynamics (00:29:24) The role of strategic breaks (00:31:27) Focusing on strengths over weaknesses (00:35:59) Managing negative thoughts and default mode network (00:43:03) Tools for creating positive thoughts (00:47:39) Healing trauma and synaptic rewiring (00:50:58) Gratitude practice and neuroplasticity (00:55:31) Longevity and healthy aging (01:01:20) Nicole's perspective on living past 100 Sponsors: Timeline | Go to TimelineNutrition.com/Dave to get 10% off your first order. Apollo Neuro | Head to ApolloNeuro.com/DaveAsprey to save 15% on an Apollo Wearable Resources: Nicole’s new book, “Rewire” is out now! Go to NicolesNeuroScience.com Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Nicole on Instagram: @nicolesneuroscience Learn How To Sleep: SleepWithDave.com Follow Dave on Instagram: @Dave.Asprey Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr. Cate Shanahan returns to share vital insights on the dangers of seed oils and their impact on health. As a well-known Cornell-trained physician and author, Dr. Cate has spent years researching and advocating against the use of harmful vegetable oils. In this episode you’ll learn about the "Hateful Eight" oils and why they are detrimental to metabolic health. Dr. Cate explains the connection between these oils and chronic diseases, such as heart disease and diabetes. You will understand how to read labels to avoid these oils in everyday foods and get practical tips for making healthier dietary choices. Dr. Cate also covers the history and influence of the American Heart Association on dietary recommendations, revealing some eye-opening truths. Key takeaways you’ll gain include understanding the role of oxidative stress, the importance of choosing the right fats for a healthy diet, and how avoiding these oils can improve overall well-being.Timestamps: 00:00:00 — Opening 00:01:46 — Welcome and Introduction of Dr. Cate Shanahan 00:02:34 — The Reality of Food Deserts and Vegetable Oils 00:04:01 — The Ultra Wealthy and Their Dietary Choices 00:05:42 — Dr. Cate’s Personal Journey to Understanding Fats 00:11:10 — The Benefits of Avoiding Seed Oils 00:12:08 — The Hateful Eight Oils 00:19:07 — American Heart Association and Proctor & Gamble 00:28:15 — The Importance of Avoiding Oxidized Oils 00:39:05 — Clarifying Misconceptions About Omega-6 00:50:18 — The Impact of Diet on Family Structures 01:00:24 — The Role of Testosterone and Endocrine Disruptors 01:15:29 — Understanding Insulin Resistance 01:25:00 — The Slippery Slope of Statin Use 01:45:00 — Practical Tips for Avoiding Vegetable Oils 01:52:01 — Conclusion Sponsors: ARMRA | Go to TryARMRA.com and use the code DAVE to get 15% off your first order. Leela Quantum | Visit LeelaQ.com/Dave for 10% off. Resources: Dr. Cate’s book, “Dark Calories” is available for pre-order now! The book comes out on June 11th.Learn more about Dr. Cate: https://drcate.com/ Dr. Cate's Instagram: @drcaseyskitchen Levels’ Instagram: @DrCateShanahan Dave Asprey’s book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, you’ll learn how to enhance your health and longevity with insights from Dr. Casey Means, a Stanford-trained physician and co-founder of the metabolic health company, Levels. You’ll learn how to achieve good energy by enhancing metabolic health. Dr. Means shares valuable information on how food choices, metabolism, and chronic diseases are interconnected. She explains the science behind mitochondrial function and how your everyday choices impact your body's ability to generate energy. This episode offers practical tips for improving your metabolic health, covering areas such as diet, sleep, stress management, and reducing inflammation. You’ll hear about the importance of continuous glucose monitoring and personalized health data in maintaining metabolic health. Get ready to uncover the truth about modern healthcare systems and learn how to empower yourself with knowledge. Whether you're dealing with chronic conditions or looking to enhance your health, this episode is packed with essential information to guide your journey. Timestamps: (00:00:10) Introduction and importance of metabolic health (00:01:25) The connection between food and pharma systems (00:02:29) Dr. Means' background and new book "Good Energy" (00:03:33) The metabolic foundation of chronic diseases (00:05:59) The failure of Google as a health search engine (00:06:18) The link between migraines and mitochondrial function (00:07:52) Dr. Means' transition from ENT surgeon to metabolic health expert (00:10:25) The role of inflammation in chronic diseases (00:14:16) Working with her brother on the book (00:18:07) The story of Dr. Means' mother and the healthcare system's failures (00:20:55) Empowering patients with their health data (00:22:32) Addressing fear and misinformation in healthcare (00:30:44) First steps to improving metabolic health (00:37:17) The impact of fear on health (00:44:20) The concept of biochemical fear (00:50:04) Integrating natural signals into modern life Sponsors: Calroy | Head over to Calroy.com/Dave for an exclusive discount. Our Place | Go to FromOurPlace.com and use the code DAVE for 10% of your order. Resources: Dr. Casey book, “Good Energy” is out now. Levels Health: https://levelshealth.com Dr. Casey Means’ Instagram: @drcaseyskitchen Levels’ Instagram: @levels Levels’ YouTube: @LevelsHealth Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode, environmental journalist and seasoned activist David Steinman, with over 30 years of experience fighting against chemical toxins, shares his expertise on the impact of these harmful substances in our food supply. He highlights the serious health risks they pose, particularly to pregnant women and children, and offers practical tips on how to shield oneself and future generations from these dangers. Steinman delves into the benefits of organic foods, the effectiveness of water filtration, and the impact of making informed consumer choices.  Through insights from his latest book, "Raising Healthy Kids," he equips listeners with the necessary tools to reduce toxin exposure and advocate for a healthier lifestyle. Tune in to gain valuable knowledge on how to safeguard your health and the environment from chemical toxins.   Timestamps: (00:00:00) Introduction to the Crisis in America’s Food System (00:01:12) Introduction of David Steinman (00:02:22) Discussion on "The Better Baby Book" (00:05:09) The Impact of Pesticides on Fertility (00:10:20) Practical Advice on Water Filtration (00:21:03) The Importance of Organic Foods (00:35:30) Political Influence on Environmental Safety (00:39:46) Hope for Environmental Change (00:41:57) Personal Choices in Reducing Toxin Exposure (00:45:25) Discussing Systems Change for a Healthier Environment (00:52:15) The Significant Impact of Individual Actions (01:00:00) Conclusion: Steinman’s Call to Action   Sponsors: ZBiotics | Go to Zbiotics.com/dave for 15% off your first order. spermidineLIFE | Go to spermidineLIFE.us and use code Asprey25 at checkout for 25% off your order. ARMRA | Go to https://www.TryARMRA.com and use code Dave for 15% off.  Resources: "Raising Healthy Kids" by David Steinman is available on June 4th, 2024 Dave Asprey's book, 'Smarter Not Harder' is out now. Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

We're previewing the 10th annual Biohacking Conference in Dallas, Texas, (May 30 - June 1) on The Human Upgrade! Christian Drapeau and STEMREGEN are at the forefront of integrating plant-based innovations into regenerative medicine. By harnessing the power of unique plant extracts, STEMREGEN's approach stimulates the body's own stem cell production, providing a natural alternative to conventional stem cell therapies. This technique promotes rapid healing and rejuvenation and offers significant advancements in natural health and longevity. In this episode, delve into the groundbreaking work of Christian Drapeau presented at the upcoming Biohacking Conference. Attendees will discover how STEMREGEN plant-based solutions can dramatically increase the body's natural stem cell count, supporting faster recovery and enhanced vitality. Explore the potential of these innovations to reshape our understanding of health and wellness, paving the way for more accessible and effective regenerative treatments. Timestamps & Highlights: (00:01) Introduction to the episode and the significance of the Biohacking Conference. (01:05) Christian Drapeau's introduction and his journey in stem cell research. (01:35) Overview of STEMREGEN's new products at the Biohacking Conference. (01:58) Discussion on different types of stem cells and their applications. (03:21) Debunking myths around plant-based stem cells and their effectiveness. (04:12) Launch of new STEMREGEN products tailored for athletes and those seeking enhanced recovery. (05:08) Insights into the NSF certification process and its importance. (06:55) The role of systemic inflammation in stem cell functionality. (08:01) Introduction of STEMREGEN Mobilize to enhance capillary health. (09:17) Exploring the new STEMREGEN Signal for reducing systemic inflammation. Sponsors: STEMREGEN | Go to STEMREGEN.co/Dave for 20% off your order. Resources: 10th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com Dave Asprey's NEW Book 'Smarter Not Harder' Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Follow STEMREGEN on Instagram: @STEMREGEN See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

We're previewing the 10th annual Biohacking Conference in Dallas, Texas, (May 30 - June 1) on The Human Upgrade! Mike McIntyre and ARRC are pioneering advancements at the intersection of frequency medicine and light therapy. By utilizing photons of light to carry therapeutic frequencies, their approach, known as photobiomodulation, opens new doors to enhancing health and meditative states. This technology not only enhances physical wellbeing but also elevates spiritual and mental health, establishing it as a cornerstone of innovative wellness practices. In this episode, explore the cutting-edge applications of photobiomodulation showcased at the Biohacking Conference. Attendees will experience firsthand how ARRC's light therapy technologies can transform their health by harnessing the power of light frequencies to stimulate cellular repair and enhance meditative practices, offering a glimpse into the future of holistic health enhancement.  Timestamps:(00:01) Introduction to the episode and the Biohacking Conference. (01:12) Welcome Mike McIntyre and background into photobiomodulation. (01:55) Advancements in light therapy technology and its implications. (02:46) Discussion on using light therapy to enhance spiritual and meditative practices. (04:08) Observations on the impact of specific frequencies in light therapy. (06:02) The potential of light and frequency to influence health at a quantum level. (08:20) Benefits and experiences of using A RRC’s light therapy. (10:36) Details on session lengths and the immediate effects post-therapy. (14:29) Discussing the broader applications and scientific backing of light therapy. (16:55) Safety, side effects, and optimal dosing of light therapy treatments. (18:37) Encouragement to visit the Biohacking Conference and try out A RRC technology. Sponsors: ARRC LED | Go to ARRCLED.com to learn more!  Resources: 10th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com Dave Asprey's NEW Book 'Smarter Not Harder' Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Follow ARRCLED on Instagram: @ARRCLEDSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

We're previewing the 10th annual Biohacking Conference in Dallas, Texas, (May 30 - June 1) on The Human Upgrade! Dr. Allen Meglin and Oxy Health are at the forefront of hyperbaric medicine, a field revolutionizing the way we enhance healing and cellular health. Hyperbaric oxygen therapy, as explained by Dr. Meglin, intensifies the body's ability to regenerate by significantly improving stem cell activation and optimizing the cellular environment for recovery. This therapy not only speeds up the healing process but also boosts overall cellular function, making it a critical tool in modern medical treatments. In this episode, discover the transformative impact of hyperbaric oxygen therapy, a highlighted technology at the Biohacking Conference. Attendees will learn how this treatment enhances natural healing processes, prepares the body for stem cell therapies, and promotes profound health improvements, peeking into the future of regenerative medicine. Timestamps:(00:01) Introduction to the episode and Biohacking Conference details. (00:47) Welcome Dr. Allen Meglin and his focus on hyperbaric therapy. (01:01) Dr. Meglin’s approach to integrating hyperbarics with stem cell therapy. (02:00) The scientific basis for hyperbarics in enhancing stem cell outcomes. (03:07) Explanation of stem cells' role in natural healing processes. (04:13) Variables influencing the effectiveness of hyperbaric therapy. (06:11) Discussion on the dual effects of hyperbaric therapy: stress and relaxation. (08:52) The variety of hyperbaric chamber options and their therapeutic uses. (00:10:35) Clinical Experiences with Hyperbarics. Sponsors: Oxyhealth | Go to Oxyhealth.com to learn more Resources: 10th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com Dave Asprey's NEW Book 'Smarter Not Harder' Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Follow Oxyhealth on Instagram: @OxyhealthSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

We're previewing the 10th annual Biohacking Conference in Dallas, Texas, (May 30 - June 1) on The Human Upgrade! Dr. Patrick Porter and BrainTap are pioneers in the intersection of neuroscience and technology, transforming the way we approach mental and cognitive health. BrainTap, a device developed under Dr. Porter's guidance, merges light and sound therapy with guided visualization to enhance the brain's neuroplasticity. This technology not only offers a leap in personal development but also aligns perfectly with the biohacker's toolkit for optimized mental performance. In this episode, explore the established benefits of BrainTap technology, a favorite at the Biohacking Conference. Attendees will have the opportunity to experience firsthand how BrainTap's approach to brain enhancement can invigorate daily mental health routines, making sophisticated neuroscience accessible to individuals seeking to maximize their mental capacity. Timestamps: (00:01) Introduction to the episode and the significance of the Biohacking Conference. (01:20) Dr. Patrick Porter introduces BrainTap and its foundational science. (02:11) Latest research findings on BrainTap's impact on cognitive function and sleep improvement. (03:27) Comparing the effects of psychedelics and BrainTap on the brain's default mode network. (04:49) Discussion on the expansive use and benefits of BrainTap technology. (06:17) How BrainTap assists in the right neural pruning to enhance mental function. (08:12) Clarifying the concept of subspace in learning and brain function. (11:17) New studies on BrainTap's role in academic performance and dementia. (14:04) Community impact and personal experiences at the Biohacking Conference. Sponsors: BrainTap | Go to BrainTap.com/Dave for an exclusive offer. Resources: 10th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.com Dave Asprey's NEW Book 'Smarter Not Harder' Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

We're previewing the 10th annual Biohacking Conference in Dallas, Texas, (May 30 - June 1) on The Human Upgrade! Dr. Brandon Crawford and 528 Innovations are at the forefront of laser technology development for biohacking. Traditionally seen as a tool for medical professionals, laser technology has made significant strides in becoming accessible for personal health optimization. Dr. Crawford’s work with 528 Innovations has led to the creation of a new laser device that enhances health and performance by manipulating light to achieve precise biological effects. This episode offers insights into the technology being featured at the Biohacking Conference, where attendees can experience the latest innovations that promise to elevate personal wellness routines. By harnessing the power of advanced laser technology, 528 Innovations is setting new standards in the field, aiming to transform everyday health practices with tools previously only available to specialists. Timestamps & Highlights: (00:01) Introduction to the episode and the historical significance of lasers in biohacking. (01:04) Preview of the Biohacking Conference and the introduction of innovative technologies. (01:38) Dr. Brandon Crawford discusses the versatility and legacy of racehorse lasers in therapy. (02:04) Exploration of how high-value professionals adopt biohacking technologies. (03:03) Announcement of Dr. Crawford's new laser product at the Biohacking Conference. (04:40) Discussion on the portable design and transformative potential of the new laser. (06:07) Dr. Crawford outlines the intended impact and the platform nature of the new laser technology. (07:05) Safety features and regulatory aspects of the new laser. (08:29) Insights into the research behind the new laser and its effects on brain function. (13:12) Pricing information and the value proposition for different users (home users vs. clinicians). Sponsor: Go to 528innovations.com to learn more! Introducing the 528 Innovations 5 Series Laser Therapy Device, now available for pre-sale! Pre-order now for you chance to win! Secure this revolutionary product, launching this week and shipping later in the year. Resources: Dave Asprey's NEW Book 'Smarter Not Harder' 10th Annual Biohacking Conference: biohackingconference.com for tickets Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of "The Human Upgrade," you will learn from Dr. Elizabeth Yurth, an expert in orthopedics, cellular medicine, and regenerative medicine, about the significant health benefits of spermidine, a supplement that enhances longevity and supports robust health. Dr. Yurth discusses the crucial role of spermidine in promoting autophagy, the body's natural process for clearing out damaged cells, which can lead to better cellular health and a more youthful body. She also dives into how spermidine supports kidney health and how it can be combined with NAD to maximize anti-aging effects. Additionally, you will discover practical tips from Dr. Yurth on integrating these powerful supplements into your daily routine to maintain energy levels, improve cellular function, and sustain a vigorous and healthy life as you age. This episode provides deep insights into making informed choices about supplements that support long-term health goals. Timestamp Highlights: (00:00:01) Introduction: Background and the inception of biohacking. (00:01:08) Early biological management and its long-term benefits. (00:01:57) Misconceptions about fasting and the role of spermidine. (00:02:43) Dr. Uth's journey from orthopedics to longevity medicine. (00:06:17) Deep dive into spermidine: benefits, sources, and mechanisms. (00:10:43) Dietary sources of spermidine and its importance in diet. (00:16:02) Spermidine as a crucial nutrient for autophagy and its mechanisms. (00:19:13) Comparing spermidine with fasting and rapamycin for longevity. (00:22:25) Practical dosing advice for spermidine. (00:33:24) The optimal timing and method of spermidine supplementation. (00:41:58) Spermidine's effects on hair growth and its potential as a topical application. (01:07:17) Discussion on the future of longevity treatments and gene therapy. Sponsors:spermidineLIFE | Go to spermidineLIFE.us and use code Asprey25 at checkout for 25% off your order. EnVy | Go to envypillow.com and use code DAVE at checkout for an exclusive discount Head to QuantumUpgrade.io/Dave for a free trial Resources:Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Boulder Longevity Institute: https://boulderlongevity.com/ Follow spermidineLIFE: @spermidinelife.us Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade, Peter Diamandis shares his expert insights on using artificial intelligence to improve health and extend life. Listeners will learn about the latest advancements in AI-driven health technologies and therapeutic practices that could revolutionize wellness and longevity. Peter discusses the concept of longevity escape velocity and how close humanity is to achieving it. He also explores the economic models that might make cutting-edge therapies more accessible to a broader audience. Additionally, Peter provides personal anecdotes about his health routines, including his dietary strategies and his use of red light therapy, offering listeners practical advice on integrating these technologies into their own health regimes. This conversation sheds light on the future of health care and personal wellness, providing listeners with valuable strategies to enhance their quality of life. Timestamps: (00:00:01) Opening and introduction to the show (00:01:06) Peter's use of AI and its impact on health (00:07:42) Discussion on Ketamine and neuroplasticity (00:14:26) XPRIZE updates and new initiatives (00:17:45) The concept of longevity escape velocity (00:26:52) Financial models and accessibility of advanced therapies (00:39:13) The power of a supportive personal network (00:54:18) Peter's personal diet and longevity strategies (01:03:09) Red light therapy and its benefits (01:21:09) Closing remarks and future plans Sponsors: Calroy | Head to Calroy.com/Dave for an exclusive discount Viome | Go to Viome.com/Dave to save $110 on the Full Body Intelligence Test. Resources: Peter Diamandis Official Website | https://www.diamandis.com/ XPRIZE | https://www.xprize.org/ Purpose Finder | https://purposefinder.ai/ Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this special Upgrade Spotlight episode of "The Human Upgrade," Philipp Samor von Holtzendorff-Fehling, founder and CEO of Quantum Upgrade and Leela Quantum, joins the show to talk about quantum energy. Since his last appearance on the show, Philipp has made significant advances in harnessing quantum energy to promote health and wellness. You'll learn about the science behind quantum energy, how it can positively impact your life, and the practical ways you can use this technology to boost your own health, mood, and vitality. Philipp also shares insights into the journey that led him from a high-stress corporate world to pioneering in holistic health innovations, offering you inspiration and actionable tips to apply in your daily life. Join us to see how the latest in quantum energy can make a real difference in how you feel every day. Timestamps: (00:01:03) Introduction to Quantum Energy and Biohacking (00:04:51) Philipp's Journey from Corporate to Quantum Healing (00:12:27) Understanding Quantum Systems and Human Biology (00:16:32) The Science and Technology behind Quantum Upgrade (00:21:10) Evidence and Impact of Quantum Energy Devices (00:29:17) Expanding Human Consciousness through Quantum Fields (00:33:27) The Future of Health and Quantum Technologies (00:38:34) How Quantum Energy Can Shape Our Health and Environment (00:40:54) Philosophical Insights on Energy, Consciousness, and Healing (00:50:18) Closing Thoughts and How to Access Quantum Technologies Sponsors: Go to QuantumUpgrade.io/Dave and get a 14 Day Free Trial Resources: Follow Philipp on Instagram: https://www.instagram.com/philipp_vhf/ Quantum Upgrade Instagram: https://www.instagram.com/quantumupgrade.io/ Dave Asprey’s Book ‘Smarter Not Harder:’ https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this special "Asprey Archive" episode of The Human Upgrade, you’ll find out why you’re tired, how to fix it and ways to increase your energy. Fatigue is a hidden epidemic, with chronic fatigue syndrome being the most severe end, but most people (in the U.S.) are experiencing some level of being flat-out tired as hell.Our guest is Ari Whitten, Ph.D. (Cand.), CES, PES, who came on the show in 2022. Ari argues that as a culture, we have normalized fatigue. In his book, “EAT FOR ENERGY: How to Beat Fatigue, Supercharge Your Mitochondria, and Unlock All-Day Energy,” he explains that 5.4 million adults in the U.S. have been diagnosed with chronic fatigue syndrome (the most severe case of fatigue). However, the true fatigue epidemic affects 50 to 100 times more people.Ari outlines the major factors impacting mitochondrial health, including poor sleep, excess body fat, and an unhealthy gut, and offers solutions like nutritional strategies and key supplements to enhance energy. With over 25 years in natural health science and a personal history with chronic fatigue, Ari brings invaluable insights into combating fatigue through his Energy Blueprint programs and podcast, where he connects with experts on revitalizing human energy.Sponsors:Pendulum | Get 20% off membership at https://pendulumlife.com with code Asprey20 ARMRA | Go to https://www.TryARMRA.com and use code Dave for 15% off Resources:Ari's book: FOR ENERGY: How to Beat Fatigue, Supercharge Your Mitochondria, and Unlock All-Day EnergyDave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

On today's episode, Jerry Colonna shares his transformative journey from a high-powered venture capitalist to a Buddhist coach. You'll learn about the profound impact of “radical self-inquiry" on leadership and life, illustrating how deep personal development can reshape personal and professional relationships. You'll also learn how mindfulness and self-awareness are crucial for effective leadership. Whether you're a seasoned leader or simply aspiring to improve, this conversation offers invaluable insights into executive coaching, Buddhism and personal transformation, making it essential for anyone aiming to foster a compassion and understanding. Highlights:(00:01:01) - Jerry Colonna's Transformative Journey (00:05:51) - The Impact of Material Success (00:13:27) - Mindfulness in Leadership (00:17:32) - Deep Mental States Through Meditation (00:22:10) - Themes of 'Reunion' (00:30:17) - Philosophy of Radical Self-Inquiry (00:34:27) - Leadership and Self-Awareness (00:39:34) - The Practice of Continuous Personal Development (00:41:54) - Becoming a Leadership Coach (00:51:18) - Connecting Mindfulness with Professional Relationships (00:56:10) - Long-Term Benefits of Self-Inquiry (01:00:42) - Insights from Executive Coaching (01:03:00) - Future of Leadership and Compassion  Sponsors: LEELA Q | Visit LeelaQ.com/Dave for 10% off Timeline Nutrition | Go to TimelineNutrition.com/Dave and get 10% off your first order.  Resources: Jerry’s Website - https://www.reboot.io/team/jerry-colonna/ Jerry’s Book – Reunion: Leadership and the Longing to Belong Follow Jerry on Instagram: @Jerry.Colonna Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today on The Human Upgrade, Dr. Anurag Singh, a renowned expert in muscle biology and aging, shares his expertise on the impact of GLP-1 agonists like Ozempic and Wegovy on weight loss, muscle health, and aging. In this episode, you'll learn about the science behind these popular drugs, their potential benefits, and the risks involved. Discover how you can maintain muscle mass while losing weight, enhance your mitochondrial function for better health, and what the future holds for medical treatments in weight management. Gain expert insights into making smart choices for your long-term health and wellness, whether you're considering these treatments or just curious about new health technologies. Timestamped Highlights: (00:00:00) Introduction to GLP-1 agonists and their popularity in weight loss. (00:01:40) Guest introduction: Dr. Anurag Singh's expertise and background. (00:02:50) Dr. Singh discusses the primary functions and uses of GLP-1 drugs. (00:06:23) The significant muscle loss associated with GLP-1 drug use. (00:10:01) Addressing common misconceptions and concerns about GLP-1 agonists. (00:15:34) How GLP-1 agonists affect mitochondrial function and overall metabolism. (00:20:30) Comparing the effects of fasting to GLP-1 drugs on weight loss and muscle preservation. (00:28:43) New testing methods for mitochondrial function and their implications. (00:35:00) Potential future directions in GLP-1 treatment and muscle preservation strategies. (00:41:48) The concept of 'Ozempic face' and its effects on personal appearance and self-esteem. (00:50:04) Discussion on 'Urolithin A' and its role in mitochondrial health and muscle strength. (01:04:02) Predictions for the next innovations in weight loss and muscle health treatments. Resources: Vitamin Dake | www.VitaminDAKE.com Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/ Sponsors: STEMREGEN | Go to www.STEMREGEN.CO/DAVE for 20% Off Timeline Nutrition | Go to www.TimelineNutrition.com/Dave for an exclusive discount.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today's episode focuses on Cancer with a true expert, Mark Lintern. You'll learn about the surprising links between infections, inflammation, and our body's powerhouses - the mitochondria. This is a chance to arm yourself with cutting-edge theories that could change the way we treat cancer. Simple changes in treatment perspectives might be the key to unlocking new ways to tackle cancer and by the end of this episode, you'll have a fresh arsenal of knowledge to rethink cancer's causes and solutions. This is an eye-opening discussion that promises to transform the way we approach this formidable disease. Timestamp Highlights: (00:00:01) Introduction to a new theory about cancer (00:01:08) The interplay between mitochondrial dysfunction and genetic factors (00:02:08) Evaluating cancer from a citizen scientist's perspective (00:03:15) Challenging mainstream cancer narratives with personal research (00:07:49) How biases affect cancer research and therapy development (00:09:40) Exploring the Warburg effect in cancer metabolism (00:23:05) Investigating pathogens as a potential trigger for the Warburg effect (00:27:18) Fungal connections to chronic disease and cancer (00:35:32) How pathogens and inflammation contribute to cancer's growth (00:37:37) Importance of addressing inflammation and fungal infections in cancer (00:43:32) Estrogen's role in cancer promotion (00:47:10) The connection between methyl deficiency and cancer (00:49:17) Metformin's dual role in blood sugar regulation and antifungal activity (00:50:01) Wrapping up the conversation with final insights  Sponsors: ARRC LED | For More Information Visit www.ARRCLED.COM EnVy | Upgrade your sleep and skin health now at www.enVyPillow.com, use code DAVE10 at checkout.  Resources:  https://www.cellsuppression.com/ Help Mark advance his research: https://www.gofundme.com/f/help-mark-lintern-advance-cancer-treatment Website - www.cellsuppression.com Book - The Cancer Resolution Follow Yes To Life: @YesToLifeCharity Donate to Yes To Life: https://yestolife.org.uk/ Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast Moldy Movie: www.MoldyMovie.com Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Get ready for a journey that takes you beyond the pain of heartbreak and into a world where loss transforms into growth with science journalist Florence Williams, who shares her personal triumph over the heartbreak of divorce, which inspired her to write a book on the subject. This episode sheds light on how heartbreak reshapes our bodies and minds. You'll gain valuable tactics for emotional healing, understand the crucial role of touch in regaining trust, and see how therapeutic practices like EMDR and rituals can offer relief. For those on the mend or helping others heal, this discussion is packed with practical advice to help you transform the trials of heartbreak into a journey of empowerment. This episode provides clear steps to recover and emerge stronger from life's emotional challenges. Timestamp Highlights (00:02:26) Florence Williams’ Journey Through Divorce (00:07:42) Divorce as a Story of Inflammation (00:13:43) Rebuilding Connection Post-Heartbreak (00:18:02) Embracing Beauty and Awe in Healing (00:23:22) Therapeutic Use of Psychedelics in Overcoming Heartbreak (00:34:33) Reestablishing Trust After Betrayal (00:38:04) The Healing Power of Touch and Oxytocin (00:44:51) Safe Relationships and Self-Discovery Post-Divorce (00:50:33) Journaling as a Tool for Processing Emotions Sponsors ARMRA | Go to https://www.TryARMRA.com and use code Dave for 15% off BEAM Minerals | Go to www.Beam Minerals.com/Dave2024 for 20% off your first order. Resources Get your copy of ‘Heartbreak’ by Florence Williams: https://www.florencewilliams.com/books-2 Florence Williams website: https://www.florencewilliams.com/ Follow Florence Williams: @Florence999 Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey Follow The Human Upgrade: @TheHumanUpgradePodcast See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Managing your stress effectively and building resilience just got easier with Dr. Aditi Nerurkar's guidance on The Human Upgrade. This episode tackles 'toxic resilience,' revealing its impacts on health and well-being. You'll gain insights into the HPA axis—the body's command center for stress response—and learn practical techniques to turn stress into a growth tool. Dr. Aditi introduces the 'Rule of Two,' a simple yet powerful approach to adapting to stress and shows how neuroplasticity can retrain your brain for better stress management. You'll also discover tips for setting digital boundaries, fostering gratitude, managing a full email inbox, and understanding the connections between stress management and longevity. It's all about taking actionable steps toward a more resilient, empowered life.Timestamp Highlights:(00:01:21) - The Pressures of the Pandemic and the Surge in Stress (00:02:08) - Introducing Dr. Aditi Nerurkar and Her Journey Through Burnout (00:05:06) - The Concept of 'Toxic Resilience' and Sustainable Stress Management (00:10:16) - The Physiological Responses to Stress and the HPA Axis (00:12:12) - Transforming Stress from Maladaptive to Adaptive (00:17:16) - The Importance of Understanding Personal Stress Thresholds (00:21:06) - Empowering Change and Managing Internal Alerts (00:25:15) - The 'Rule of Two' in Stress Adaptation (00:32:21) - The Role of Neuroplasticity in Resilience (00:37:13) - Combining Conventional Medicine with Stress Management Techniques (00:39:29) - How Dr. Nerurkar Achieves an 'Inbox Zero' Lifestyle (00:40:59) - The Connection Between Stress Management and Longevity Sponsors Pendulum | Get 20% off membership at https://pendulumlife.com with code Asprey20 Timeline Nutrition | Go to https://www.timeline.com/dave and get 10% off your first order.  Resources Get your copy of ‘The 5 Resets’ by Dr. Aditi Nerurkar Follow Dr. Aditi on Instagram: @draditinerurkar Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dave on Instagram: @Dave.Asprey See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this special Asprey Archive episode you’ll learn that while yes, testosterone fuels energy and performance, it’s not the be-all and end-all solution for men’s health woes. A systems biology approach considers many other aspects and provides a broader perspective about what’s going on with you.This conversation features board-certified urologist Tracy Gapin, M.D. He joined us in 2022 for this episode to discuss new ways for men to improve their health and performance. He uses epigenetic coaching, hormones, peptide therapy, biometric monitoring, and unique nutrition and lifestyle interventions.In his book, “Male 2.0™: Cracking the Code to Limitless Health and Vitality,” he says medical school, residency training and even a two-decade career in urology and surgery specialties didn’t teach him how to get to root causes of men’s issues and solve them. He had a health crash of his own at 42. Since neither he nor his doctor had good answers, he went on a quest of discovery and change. He founded the Gapin Institute for High Performance Medicine and created the proprietary N1 Performance Health Program to go beyond conventional options.This conversation goes even further into what creates epigenetic signals that affect the function and expression of your genes. You’ll learn, too, that your mindset, stress and environment—and how you do or don’t control those things—have everything to do with your energy and focus. If you’re aiming for higher performance, Dr. Tracy suggests a trifecta that makes sleep a priority, builds resilience to stress, and creates consistent behaviors with intention.Sponsors:EnVy | Go to https://www.envypillow.com/ and use code DAVE10 at checkout for an exclusive discount.Resources:Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: Gapin Institute for High Performance MedicineInstagram: @DrTracyGapinInstagram: @Dave.AspreyYouTube: @DaveAspreyBPRSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In today’s episode you’ll explore the complexities of memory with Dr. Charan Ranganath, a top expert in cognitive neuroscience. This episode takes you through the fascinating ways our brains record, process, and utilize memories to navigate daily life and shape our futures. You’ll learn how memory impacts decision-making, the truth about common myths, and the role of groundbreaking research in our understanding of cognitive function. Dr. Ranganath shares insights from his book "Why We Remember," shedding light on the brain's ability to predict and prepare for what comes next. Whether you're a seasoned biohacker or just starting, this conversation offers valuable perspectives on the science of memory that will change how you think about your mind.Timestamp highlights (00:01:03) The Role of Memory in Shaping Our Reality (00:04:51) The Truth about Remembering and Forgetting (00:12:27) Psychedelics, Plasticity, and the Future of Memory Research (00:16:32) The Ethics of Memory Enhancement (00:21:10) Harnessing Memory for Predicting the Future (00:29:17) How Memory Evolves with Age (00:33:27) The Power of Pattern Recognition in Human Intelligence (00:38:34) Debunking Memory Myths with Dr. Ranganath (00:40:54) The Role of Diet and Lifestyle in Memory Preservation (00:50:18) What 'Spider Sense' Says About Our Predictive Brains (00:55:10) Building a Life of Meaningful Memories (00:59:42) How Long Would You Want to Live if Your Memory Stayed Intact? Sponsors Sunlighten | Head to Sunlighten.com/dave to save up to $600 STEMREGEN | Go to STEMREGEN.co/Dave for 20% off  Resources Get your copy of 'Why We Remember' by Dr. Charan Ranganath Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dr. Ranganath on Instagram: @TheMemoryDoc See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Join Dave Asprey for a fascinating discussion with Colleen Cutcliffe, Ph.D., on leveraging the power of GLP-1 for natural weight management and overall well-being. Discover how probiotics can naturally stimulate GLP-1 production in the body, helping reduce food cravings and maintain a healthy gut lining. We delve into the differences between pharmaceuticals and natural probiotics, the importance of GLP-1 for longevity, and practical tips for optimizing your microbiome health. Whether you're battling cravings or seeking to prevent diabetes and its associated risks, this episode sheds light on natural, effective strategies for a healthier life. Timestamp Highlights: (00:00:01) Introduction to GLP-1 and weight management (00:01:06) Colleen Cutcliffe, PhD, on natural ways to stimulate GLP-1 (00:04:41) The role of microbiome in regulating GLP-1 and cravings (00:16:00) The GLP-1 probiotic: benefits beyond weight loss (00:34:13) Dietary interventions to support GLP-1 probiotics (00:42:23) Personal experiences and results with GLP-1 probiotics (00:51:01) The different pendulum products and who should take them (00:59:23) How GLP-1 probiotics impact the gut lining and overall health (01:03:56) GLP-1 and its connection to longevity and disease prevention Sponsors: Pendulum | Get 20% off membership at https://pendulumlife.com with code Asprey20 ARMRA | Go to https://www.TryARMRA.com and use code Dave for 15% off ARRC LED | For More Information Visit ARRCLED.com Resources: Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Instagram: @Dave.Asprey Pendulum GLP-1 Probiotics: https://pendulumlife.com (Code: Asprey20 for 20% off) Instagram: @pendulumlifecoSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today you'll step inside the real world of fame with Ramon Hervey II, the mastermind manager behind iconic figures like Vanessa Williams, Bette Midler, and Richard Pryor. He is author of "The Fame Game: An Insider's Playbook for Earning Your 15 Minutes." With years of experience guiding celebrity journeys, Ramon dismantles the myths surrounding fame and success. In this episode, he shares invaluable insights on why pouring your heart into your work and letting excellence lead is more fulfilling and enduring than the pursuit of fame. Ramon, a Master of Media and public perception, brings a wealth of knowledge from his time shaping the narratives of household names. Get ready to redefine your ambitions and align your pursuits with the values that truly matter. You’ll step beyond the veneer of fame into a world where your achievements stand the test of time. (00:00:06) Introduction to the complexities of fame (00:01:06) Ramon's correction and insights into the unpredictability of fame (00:04:04) The statistical rarity of becoming famous (00:06:03) The truth behind fabricating fame in the entertainment industry (00:09:18) The importance of authenticity and integrity (00:21:54) Ramon's experience with the toxic side of fame (00:29:32) The gratitude for positive fan interactions (00:32:13) Ramon's advice for influencers on handling fame (00:41:19) How industries can shift and impact your fame (00:42:27) Dave's creation of the biohacking movement (00:48:41) The strategic management of public image and fame (00:52:10) The dangers of seeking fame for fame's sake (00:58:55) The misuse of fame and its consequences (01:07:13) The role of media and public perception (01:14:04) Ramon's take on fame as currency and liability (01:20:22) The Tenets of Fame - managing fame without destruction Sponsors: Timeline Nutrition | Go to https://www.timeline.com/dave and get 10% off your first order 40 Years of Zen | Go to https://www.40YearsOfZen.com/Dave for an exclusive offer.Resources: Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: www.herveyandcompany.com IG - @trichemon FB - Ramon Hervey II Twitter: @coolramon See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today you’ll learn about female hormones: what they are, what they do, and what disrupts them. You’ll learn about the hormonal shifts that happen at different ages and life stages and get tips on how to balance hormones and make them work for you, not against you.This conversation features Anna Cabeca, D.O.. Dr. Anna is a Doctor of Osteopathy who’s triple-board certified in gynecology and obstetrics, integrative medicine, and anti-aging and regenerative medicine. She has additional certifications in functional medicine, sexual health, and bioidentical hormone replacement therapy. She joins this special preview episode to talk about female hormones. It’s her particular area of expertise and one of The Human Upgrade’s all-time Top 10 podcast topics. Today’s hormone discussion includes:How hormone disruptors go beyond stress to mold, and product and environmental toxinsHow estrogen levels change over timeWhat’s going on with progesterone, pregnenolone and DHEA, tooWhat happens to hormones during perimenopause and menopauseWhat’s causing brain fogWhat to know about bioidentical hormonesHow detoxing affects hormonesHow to keep your vaginal microbiome balancedHow “food as medicine” helps balance hormonesHow hormones influence longevityAnd much more!For the past 20 years, Dr. Anna's educated and helped women with their hormones through her private practice, books, online videos and articles. Learn more about her work with women’s hormone health:“MenuPause: Five Unique Eating Plans to Break Through Your Weight Loss Plateau and Improve Mood, Sleep, and Hot Flashes”“The Hormone Fix: Burn Fat Naturally, Boost Energy, and Stop Hot Flashes the Keto-Green™️ Way”“Keto-Green™️ 16”Sponsors:Quantum Upgrade | Go to https://quantumupgrade.io/dave for a 7-day Free TrailNeurohacker Senolytic | https://Neurohacker.com/Dave to get 15% off.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if you could catch cancer in its earliest stages, when it's most treatable—would you seize that chance? Our guest today is Dr. Josh Ofman, the president of GRAIL, and he's pioneering early cancer detection in a revolutionary new way. You'll discover the cutting-edge advances in multi-cancer early detection that are transforming the fight against this swift and silent killer. You'll also learn about the full potential of the GRAIL gallery test in your proactive health management. This technology is ushering in a new era in cancer care but also signals a paradigm shift in disease prevention. Learn why yearly screenings are your best strategy in the race against cancer. Prepare to dive deep into how the latest biotech innovations could significantly extend your life span!Timestamp Highlights (00:01:03) An Unsettling Trend in Cancer Proliferation  (00:04:51) Introducing Dr. Josh Ofman and the GRAIL Test  (00:12:27) The Revolutionary Approach of Multi-Cancer Early Detection  (00:16:32) The Shift to Biological Signals in Cancer Detection  (00:21:10) The Empowering Aspect of Knowing Your Cancer Status  (00:29:17) How GRAIL's Gallery Test Can Change the Paradigm of Cancer Treatment  (00:33:27) The Critical Nature of Annual Cancer Screening  (00:38:34) How Early Detection Affects Treatment Options and Survival  (00:40:54) The Future of GRAIL in Other Disease Pathways  (00:50:18) Combating Fear and Misconceptions Around Cancer  (00:55:10) The Impact of Socioeconomic Factors on Cancer Incidence  (00:59:42) The Pivotal Role of Data in Personalized Health Sponsors  ARRC LED | The perfect device for daily home use. For more information visit arrcled.com. Leela Quantum | Visit www.LeelaQ.com/Dave for 10% Off Resources  Dave Asprey’s NEW Book ‘Smarter Not Harder’: daveasprey.com/books  GRAIL Multi-Cancer Early Detection Test: Visit www.Galleri.com/Dave to see if you’re eligible for a $50 off limited-time online-only offer. GRAIL Research and Studies: grail.com/clinical-studies GRAIL on  Twitter: @GRAILbio See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

I had the pleasure of talking with Dr. Christina Rahm, who has an inspiring journey from a pharmaceutical executive to an advocate for integrating holistic health solutions with rigorous scientific methods. We dive into the impact of spirituality on wellness, the transformative power of neural feedback, and the intersection of technology and ethics in health. Dr. Rahm shares her insights into combating health issues with nanotechnology and discusses the influence of the environment on our well-being.(00:00:01) Introducing Dr. Christina Rahm and her diverse expertise in health and science (00:02:17) The transparency and ethics in the pharmaceutical industry (00:07:07) Transition to holistic health solutions and bioengineering innovations (00:14:10) Addressing the pervasive health effects of fungus and mold (00:27:11) Biotechnology's role in creating a brighter future for human health (00:38:04) Discussing the unexpected benefits of childhood diseases on immune function (00:50:31) Exploring annual detox rituals and their scientific basis (01:03:01) Handling criticism with humor: The "Your Mom" strategy(01:06:57) Announcement of Upgrade Labs locations and offerings  Sponsors: Mitosynergy | Exclusive offer for listeners – 15% off by going to www.Mitosynergy.com/Dave ARMRA | Go to www.TryARMRA.com and use code Dave to get 15% off your First Order Resources: Dr. Christina Rahm's website: https://drchristinarahm.com/ Root Brands: https://therootbrands.com/ Upgrade Labs: https://upgradelabs.com/ Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Dr. Chrsitina Rahm’s Instagram Page: https://www.instagram.com/drchristinarahm/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this profound episode, Maria Menounos shares her journey through significant health challenges, including a brain tumor and diabetes, and how she emerged more resilient and health focused. Renowned for her vibrant career in entertainment and now as a wellness advocate, Maria delves into the transformative power of facing mortality, redefining medicine, and leveraging biohacking to enhance her life. She gives actionable advice for those looking to preserve their health while pursuing their dreams and the importance of aligning career success with personal well-being. (00:00:01) - Maria's resilience through her health battles (00:03:29) - How health challenges can redefine life's purpose (00:14:18) - Yoga Nidra and the shift from anxiety to empowerment (00:23:25) - The importance of biohacking in Maria's recovery (00:34:16) - Sunlight and its underrated health benefits (00:47:30) - The rise of biohacking technologies and their accessibility Sponsors BiOptimizers | Go to www.bioptimizers.com/Dave for 10% off Timeline | Go to www.TimelineNutrition.com/Dave to get 10% off your first order Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Heal Squad: https://www.healsquad.com/ Maria Menounos Instagram: @mariamenounos See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, Calley Means joins the show to march onward on his war path to changing the incentives of modern health. He’s a champion of food and lifestyle practices as medicine—and, in May of this year, he’s putting out a new book on the subject which we outline today, called Good Energy.His sister, Dr. Casey Means, is the co-author of Good Energy. You know her from a past appearance on this show and as the founder of Levels so this mission really is a family affair in the best way possible.Going from a food lobbyist to the other side of the fence, Calley is a deeply serious and dedicated champion for the people. But he brings much more to the table today than a polished delivery and a new book; he is also the co-founder of True Medicine, which works to connect tax-advantaged spending to healthy food and exercise. It’s helped hundreds of thousands of people access affordable care by leveraging the convoluted systems currently in place to block them from doing so—no easy task.In this conversation, Calley lays the foundation for our food culture as it stands today—bleak, corrupt, poisoned, sick, and getting sicker. We deconstruct the layers of federal agencies and historical precedent that have brought us to this point, and we’re direct in our suggestions (demands) on how to fix it.And all the facts are laid bare. Dots are connected in broad daylight, on network television, and within the algorithms that power our social feeds. Our kids are at stake, and the only option is to take affirmative action on what we know is right. (00:01:19) Calley’s Inspirations & Metabolic Mission(00:11:16) Redefining the Meaning of Medicine (00:19:21) Is America a Viable Place To Raise Healthy Kids?(00:30:41) Meaningfully Changing Healthcare Incentives(00:42:56) Now What—How Does Society Make Positive Change?(00:49:34) The Media’s Role in Society’s False Narratives(00:56:49) Undoing the Damage of the Food PyramidSponsorsARRC LED | The perfect device for daily home use. For more information visit arrcled.com.ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Good Energy: The Surprising Connection Between Metabolism and Limitless HealthTruemed: truemed.comThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

How can we make our furry best friends live longer, healthier lives?A true pioneer in this field, Dr. Matt Kaeberlein, is here to unpack this important subject while highlighting the crossover between human and canine longevity. You read that right; this episode isn't just for dog lovers—it's a deep dive into longevity for humans, too. Dr. Matt Kaeberlein, who's the CEO of Optispan and a key figure in the Dog Aging Project, brings a wealth of knowledge from his distinguished career in aging and healthspan research. He's an Affiliate Professor at the University of Washington and a notable figure in gerontology, recognized by organizations like the American Association for the Advancement of Science and the Gerontological Society of America. Matt's work is groundbreaking, demonstrated in over 250 scientific papers on aging, numerous prestigious awards, and he's even a Fellow of several aging associations. He's on a mission to unlock the secrets of aging, not just in humans, but in our four-legged companions as well.We explore the accuracy of measuring age with telomeres versus epigenetics and get into the nitty-gritty of diet's impact on longevity for both dogs and humans, reminding us it's not just about living longer, but living well.Matt explains the impressive trial results on rapamycin for reducing age-related inflammation, a breakthrough that's not just exciting for us but also for our pets. Finally, we touch on how AI is revolutionizing our approach to understanding and extending our healthspan.For those who want to get more involved, check out dogagingproject.org. It's not every day you meet someone who's made such significant strides in understanding aging across species. So whether you're a pet parent or just passionate about extending your own health span, this episode is for you.(00:01:31) Dogs Are the Bridge Between Lab Studies & Human Longevity(00:11:09) Exploring the Impact of Diet on Longevity(00:18:50) How Our Unique Biology Impacts Aging(00:26:33) Exploring How Size & Diet Impact Health Across Species(00:37:55) Fighting Age-Related Inflammation with Rapamycin(00:56:40) AI Interventions for Longevity TestingSponsorsARMRA | Try it out for yourself at TryARMRA.com. Use code “Dave” to get 15% off your first orderSTEMREGEN | Go to STEMREGEN.co/Dave for 20% off.ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Learn More: dogagingproject.orgWebsite: optispan.lifeX: @mkaeberleinListen: The Optispan Podcast with Matt KaeberleinThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

I’m excited to welcome back Jewels Arnes, an author, ascension coach, and the founder of BioQuantum Skincare Technology. Jewels has more than 30 years of experience in energy medicine and intensive consciousness work. In today’s episode, Jewels explains scalar waves, ORMUS, and the quantum level. She shares how these concepts all contribute to her BioQuantum Skincare line and the intention she poured into the products. We also talk about how and why Jewels moved away from psychedelics and regular meditation, and how she tunes into frequencies without them. Plus, we get into the spiritual ego, how to master your triggers, the frequency of DMT, and Jewels’ role as an ascension coach. Unlike my analytical brain, Jewels sees the world through frequencies, so this was a fun conversation with fresh perspectives. (00:01:13) Dave’s Experience with ORMUS(00:06:59) Dangers of the Spiritual Ego(00:15:02) The Sphere of Spirituality & Science(00:18:11) How To Tune Into Frequencies(00:23:34) Cultivating Awareness of Our Triggers(00:27:57) Creating Products with Intention(00:32:22) What Is ORMUS?(00:38:43) Operating at the Quantum Level(00:49:22) The Frequency of DMT(00:55:23) Unboxing the BioQuantum Product Line(00:56:39) What Is Ascension Coaching?ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Shop: becomingbioquantum.com/dave to save 22% on the Scalar 33 ORMUS Activator Website: becomingbioquantum.comInstagram: @jewels.arnesInstagram: @becomingbioquantum Podcast: becomingbioquantum.com/podcastYouTube: @BecomingBioQuantum The Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What is the role of Ego? Is AI going to kill us? Is there hope for the future of our species?These are just a few of the big questions you’ll tackle in today’s enlightening and esoteric episode. I’m joined by Teal Swan, a thought leader, bestselling author, and international speaker who is on a mission to reduce human suffering. After a challenging upbringing, Teal emerged with a unique ability to talk about psychology, shadow work, and the nature of our world. Teal shares the unusual and special way she sees the world. We talk about her ESP powers, how to identify a narcissist, and her favorite dimensions. We also get into the divine masculine vs. the divine feminine, the nature of ego, and how to build trust in the world and others. (00:01:37) Finding Forgiveness in Betrayal(00:11:34) Teal’s Take on Artificial Intelligence(00:14:43) Teal Swan’s ESP Powers(00:23:22) Exploring Intention in Art(00:25:47) Upgrading Human Software & Hardware(00:27:48) How Teal Functions in the “Real” World(00:32:39) Trusting in the World(00:35:19) What’s the Nature of Ego?(00:39:14) Discovering Different Dimensions(00:42:46) Divine Feminine vs. Divine Masculine(00:52:31) Is There Hope for the Future of Our Species?(00:53:58) What Is a Synchronization Workshop?SponsorsQuantum Upgrade | Go to QuantumUpgrade.io/Dave for a 7-Day FreeMitosynergy | Get 15% off now at Mitosynergy.com/DaveResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: tealswan.comInstagram: @tealswanofficialYouTube: @TealSwanOfficialTikTok: @tealswanlivePodcast: Teal SwanThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today’s guest is none other than Shawn Stevenson. If you’re not already familiar with Shawn’s work, he’s the author of the USA Today National bestseller Eat Smarter, the international bestselling book Sleep Smarter, and the creator of the widely popular health podcast, The Model Health Show.Shawn is one of those guys who embodies peace and calm, after an impressively transformative journey stemming from a background of health challenges at least as severe as mine. After recovering, he became a researcher and nutritionist experienced in biology and nutritional science. We dive into a crucial element of biohacking I am always keen to highlight—friendship, or in this case, community.Based on research from Shawn’s latest book, Eat Smarter Family Cookbook, we talk about his current mission on the path to wellness: creating a culture of wellness around the dinner table, how communal meals impact our health and longevity, and filling the void of connection we all so desperately need these days. Shawn shares insights from his own family’s dinner table, his tips for implementing family meals into your weekly routine, and the encouraging science and data behind how it supports physical and spiritual nourishment, nervous system regulation, stress management, and more.If you like this episode, I encourage you to go pick out a good cut of meat and cook food for someone you care about—or simply do anything that's an act of service that nourishes another human being. Here’s to cultivating strong relationships, imbuing our food with love, and honoring the act of nourishing ourselves and our families.(00:01:16) Cultivating Peace & Presence Through Nervous System Regulation(00:10:00) Cultural Connections to Health, Longevity & Childhood Obesity(00:25:20) Family Dinners for Nourishment, Mindfulness & Building Stronger Bonds(00:43:45) Kids in the Kitchen: Fostering Enjoyment, Skill & Service in Cooking(00:59:48) Heart Meditations, Trauma Healing & the Science of Emotional ExchangeSponsorsBioptimizers | Go to Bioptimizers.com/Dave for 10% off any order.LeelaQ | Visit LeelaQ.com/Dave for 10% off your order.ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/booksPodcast: The Model Health ShowInstagram: @shawnmodelYouTube: The Shawn ModelRead: Eat Smarter Family Cookbook by Shawn StevensonThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today’s guest has the coolest title I’ve ever heard—mind architect. Peter Crone is a world-renowned spiritual teacher, mind-body wellness coach, and life transformation expert. He’s worked with everyone from athletes, to actors, to billionaire CEOs, to everyday people trying to do their best. Peter helps people achieve spiritual freedom, mental peace, and physical vitality, which all align with biohacking in a big way.In this episode, we dig deep into the limiting beliefs that shape our behavior and relationships. We talk about discerning between reality and the stories we tell ourselves. Peter gives advice on overcoming perfectionism, strengthening your intuition, and recognizing your innate value. We also explore how to reframe language, the value of curiosity, and how to harness losses into learnings that unlock your greatest potential. It’s a fascinating conversation. You can hear more from Peter at the upcoming Biohacking Conference. Get your tickets at biohackingconference.com. (00:03:33) Where Biohacking Meets Energy Work(00:06:28) Accessing a Spiritual State Without Drugs(00:11:04) Recovering From Perfectionism(00:19:14) Reality vs. the Stories We Tell Ourselves(00:29:42) Healing Wounds From Birth(00:38:31) Why Fear Is the Enemy of Health(00:43:18) How To Train & Strengthen Intuition(00:56:01) Recognizing Your Innate Value(01:03:30) How Can We Learn From Our Elders?(01:06:19) Peter’s Freedom ProgramSponsorsTimeline Nutrition | Go to TimelineNutrition.com/Dave to get 10% off your first order.ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: petercrone.comInstagram: @petercroneFacebook: Peter Crone - The Mind Architect TikTok: @petercroneofficial YouTube: @PeterCroneOfficialThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, we're diving into a topic that's on everyone's mind, but often misunderstood: gluten. Joining the show on this gluten-decoding mission is none other than Dr. Peter Osborne, aka the Gluten-Free Warrior. Dr. Osborne is a powerhouse of knowledge in nutritional health, particularly regarding gluten sensitivity and food allergies. As the founder of Gluten Free Society, the author of the bestseller, No Grain No Pain, and the host of the Glutenology MasterClass Series, he's at the forefront of functional medicine, helping countless individuals combat chronic and autoimmune diseases. His insights are crucial for anyone navigating the complexities of a gluten-free life.In this episode, we explain why gluten isn’t good for anyone—even if you don’t have symptoms or a diagnosed celiac problem. As a foundation, we lay out the differences between gluten sensitivity and celiac disease, covering the surprising connections between dairy, gluten allergies, and mold. Dr. Osborne also highlights why common gluten-free substitutes like corn, oats, and rice aren't the safe havens we wish we were. You’ll hear about the nefarious ways Big Food is keeping our country sick and how to start taking charge of your own health in simple, free ways.Dr. Osborne shares his recommended diet, the rule of thirds, and how to effectively shift your eating habits. He recognizes the frustration and struggle many people face in finding effective professional help, and shares his tips for spearheading your own healing while collaborating with competent professionals.This episode isn't just about gluten; it's a deep dive into understanding your body, your diet, and how to collaborate with your doctor to find the health solutions that work for you.(00:01:48) Why We Should All Be Gluten Free(00:11:46) Big Food’s Role in Our Declining Health(00:28:31) When to Enjoy (and Avoid) Sugar, Soybeans & High Oxalate Foods(00:42:39) Change Your Diet & Biohack Your Way to Better Health(01:00:15) How To Respectfully Advocate for Your Own HealthSponsorsBEAM Minerals Pets | Go to BeamMinerals.com/DAVE2024 for 20% off your first order.Viome | Go to Viome.com/Dave to save $110 on the Full Body Intelligence Test.ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: drpeterosborne.comRead: No Grain, No Pain by Peter OsborneYouTube: Peter OsborneInstagram: @drosborneThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today we’re talking about something a little different—the “weird,” esoteric, metaphysical stuff. I’m joined by Laura Coe, who was a successful healthcare tech entrepreneur before selling her company and returning to her passion for philosophy. She is now an author, certified life coach, and Akashic Records reader. Never heard of the Akashic Records? Laura explains exactly what they are, and how they can help you understand yourself on a deeper level to find more joy, peace, and prosperity in your life. We explore the big questions… Who can access the Records? How do you know if they’re even real? Then, we get into the nitty gritty… How do you learn to read them? What can you ask and not ask? Can they help you sell your house or make more money? Laura and I also talk about how to tap into your intuition as an entrepreneur, the stigmas against spirituality, and why more of us than we think probably have psychic gifts. If you’re skeptical of this stuff, I’m going to ask you to suspend your disbelief and listen with an open mind. Laura’s perspective will give you a lot to think about. Why not give it a try? (00:03:47) What Are The Akashic Records?(00:13:15) The Akashic Records as a Grid of Interconnection(00:18:47) Validating The Akashic Records for Skeptics(00:23:37) Coming Out As Spiritual(00:26:53) How Long Does It Take To Learn The Akashic Records?(00:29:42) The Craziest Questions People Ask(00:32:39) Listening to Your Inner Knowing(00:38:01) What Can’t You Ask The Akashic Records?(00:41:55) Sentences That Open the Records(00:47:22) Healing Yourself Through Healing Others(00:48:54) Can It Help You Sell Your House?(00:56:11) Taking the “Woo Woo” out of The Akashic RecordsSponsorsMitosynergy | Get 15% off now at Mitosynergy.com/DaveCalroy.com | Head over to Calroy.com/Dave for an exclusive discountResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: lauracoe.comThe Little Soul School: littlesoul.schoolRead The Nature Of Series: lauracoe.com/booksInstagram: @laurascoeThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today I’m talking with one of the most sought-after celebrity trainers on the planet. Jason Walsh has trained stars like Matt Damon, Miles Teller, Brie Larson, and Bradley Cooper for some of the most physically demanding roles of their careers. He’s also the founder of Rise Nation, a global fitness studio powered by the VersaClimber, where you train like an athlete. On today’s episode, we talk about how Jason rose to success as a celebrity trainer. He shares the moments that defined his life and career, plus his advice for anyone who wants to get started in the fitness industry. We also go deep on the painful parts of entrepreneurship—unpacking the betrayals and heartbreaks we’ve both experienced as founders. We explore ways to train your brain and your body for resiliency, and how to redefine forgiveness as an energetic shift. We also talk about Jason’s new protein company, Rise 311. Plus, his take on why you don’t need to train for an hour a day to get results. (00:02:06) How Jason Became a Celebrity Trainer (00:22:22) The Rewards of Being Disciplined (00:25:40) How to Rise in Your Fitness Career(00:33:52) Building Rise Nation Step by Step (00:40:13) The War Against Small Businesses (00:42:47) Heartbreaks & Betrayals in Business (00:48:23) Train Your Brain to Reframe Trauma (00:53:47) Redefining Forgiveness (01:00:33) The Rise of Rise 311(01:02:32) Finding Joy & Resilience SponsorsMitosynergy | Get 15% off now at https://Mitosynergy.com/DaveCalroy | Go to https://Calroy.com/Dave for an exclusive discountResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: rise-nation.comRise 311: rise311.comInstagram: @risenationJason’s Instagram: @risemovementTikTok: @climbrisenationThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Blood sugar management as a biohack captures attention for its innovative approach to health. Today's guest, Jessie Inchauspé, stands out as an expert in guiding practical glucose management, smarter nutritional choices, and unveiling the intricate relationship between diet, blood sugar levels, and overall well-being. Behind the popular Instagram account @GlucoseGoddess, Jessie educates millions on groundbreaking food habits and has achieved notable success as a French biochemist and New York Times bestselling author, with over a million copies sold of her works, "Glucose Revolution" and "The Glucose Goddess Method," in 40 languages.Her unique combination of mathematics and biochemistry expertise opens up the secrets of blood sugar and its significant impact on physical and mental health. The conversation zeroes in on Jessie's mission to make complex science accessible through simple, transformative tips. Topics include her groundbreaking research, The Glucose Method study, the launch of her Anti-Spike supplement, and her signature four hacks for glucose management after consuming carbs. The dialogue also covers the benefits of real versus fake sugar, the underlying causes of insulin resistance and diabetes, and how blood sugar spikes influence aging.This episode unveils Jessie's remarkable discoveries and biohacks for glucose management, which are crucial for fertility, PCOS, and understanding the health impacts of lifestyle choices like alcohol and nicotine. Jessie's practical insights offer a path to enjoying favored foods with minimal bodily impact, appealing to both biohacking aficionados and those embarking on a health journey.(00:02:28) Understanding Glucose’s Role in Our Health(00:14:27) Enjoying Carbs Without Negative Side Effects(00:23:27) The Real Cause of Insulin Resistance & Diabetes(00:34:23) Addressing Alcohol, Nicotine & The French Paradox(00:54:22) The Glucose Goddess Method Study(01:05:47) Glucose Management for Fertility, PCOS & PMS CravingsSponsorsTimeline Nutrition | Go to TimelineNutrition.com/Dave and get 10% off your order.Sunlighten | Head to Sunlighten.com/dave to save up to $600 when you order.ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: glucosegoddess.comInstagram: @glucosegoddess Read: Glucose Revolution by Jessie InchauspéRead: The Glucose Goddess Method by Jessie InchauspéThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today we're talking about testosterone replacement and unpacking the novel concepts of progressive overload and variable resistance training—both methods to gain, and keep, muscle mass in your body without living in the gym.I’m joined by strength expert, entrepreneur, past guest of the show, and PhD, John Jaquish. John has spent years researching and developing improved approaches to health. Inventor of X3, a technology that is proven to develop muscle much faster than conventional weight lifting with the lowest risk of joint injury, Dr. Jaquish’s methods are used in training the world's most elite athletes as well as Olympians.Aligning with the most basic tenet of biohacking, if you can achieve all of your physical or athletic goals in half the time of your competitors, why not explore the option? John is as gracious as he is informed in this one, detailing the benefits of variable resistance training and indulging me in a super deep dive into diet and nutrition experimentation, testosterone replacement therapy, and efficient muscle growth.You’ll learn what he eats every day to look as good as he does. You’ll get repetition-count-specific recommendations on ultra-quick workout routines. And you’ll learn the very surprising amount of carbohydrates I ingest every single day (a number that will shock many of you).SponsorsBEAM Minerals Pets | Go to BeamMinerals.com/DAVE2024 for 20% off your first order.ARMRA | Try it out for yourself at tryarmra.com. Use code DAVE to get 15% off your first order.(00:02:39) Masterclass on Efficient Muscle Building(00:16:43) How are Shaolin Monks & Gymnasts So Strong?  (00:23:46) Testosterone Replacement Therapy (TRT)(00:38:40) How Protein Impacts Muscle Growth(00:47:55) Breakthrough Personal Research on Carbohydrates(00:58:31) Weight Lifting is a Waste of TimeResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: jaquishbiomedical.comInstagram: @drjaquishYouTube: Jaquish BiomedicalRead: Weight Lifting Is a Waste of TimeRead: Osteogenic Loading: A New Modality To Facilitate Bone Density DevelopmentHow to Build Strength Faster – John Jaquish, Ph.D. #863Building Strength Isn’t About Weight Lifting Anymore – John Jaquish, Ph.D. #862The Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Welcome to a special Upgrade Spotlight Edition, where I introduce you to someone who's genuinely changing the game. Our carefully selected guest today is a renowned pharmacist, an author, and a pioneer in biohacking for skin longevity: Dr. Nayan Patel. Dr. Patel is a trailblazer in the world of antioxidants, specifically glutathione. If you've been following biohacking or are a regular listener, you know that glutathione is a key antioxidant with vital functions, including skin health. Dr. Patel's expertise in absorbable glutathione and anti-aging sciences is unparalleled.Dr. Patel holds a unique patent for transdermal glutathione delivery, a groundbreaking method of introducing this crucial antioxidant directly through your skin with his company Auro Wellness. His book, The Glutathione Revolution, dives deep into this topic. In this episode, we delve into why glutathione is essential for skin longevity. Dr. Patel shares insights on his innovative formula and technology for absorption at Auro Wellness, which has shown promising results in reducing fine lines, cellulite, and even promoting hair growth. As someone who champions scientifically-backed products and real results, I'm excited to discuss how Dr. Patel's work is a true game changer. I know the power of glutathione. I've been using it for nearly two decades, especially during my battle with toxic mold exposure. And now, thanks to innovators like Dr. Patel, we're moving from intravenous methods to transdermal applications—it's truly revolutionary. For those eager to try, visit aurowellness.com and use code DAVE10 for a discount.(00:01:14) Biohacking Benefits of Glutathione & New Absorption Technology(00:08:32) The Auro Skincare Stack & How Glutathione Enhances Skin Longevity(00:20:13) Reducing Cellulite & Fine Lines with Glutathione (00:35:01) Glutathione for Hair Growth & Toxin RemovalResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Shop Auro Wellness: aurowellness.com (use code DAVE10 for 10% off)Read: The Glutathione Revolution by Dr. Nayan Patel and Dr. Mark HymanThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

I’m pumped to welcome one of the hosts of the Mind Pump Podcast, top trainer and entrepreneur Sal Di Stefano. Mind Pump pulls back the curtain on the health, fitness, and nutrition industries, cuts through the pseudo-science, and offers science-backed solutions for enhancing performance while emphasizing health. Sal started his journey in the gym at age 14, and I admire how he’s steadily grown a meaningful business around biohacking fitness. On today’s episode, we take on some weighty topics like weight training vs. cardio, why veganism is dangerous, and why reverse dieting may actually be the key for results. Sal explains his fitness philosophy, which focuses on functional movement, reframing your mindset around exercise, and consistency above all else. We also get into the nutrition side of things. Sal and I break down how much protein you should be eating per day, plus our favorite proteins—and the evil ones we avoid. We also talk carbs. Do they make you fat? How do they impact performance? What are the best sources? Then, we get fired up talking about how you can fire up your metabolism. This episode is for everyone, from gym newbies to serious bodybuilders. And check out my episode on The Mind Pump Podcast to get a double dose of me and Sal (watch or listen).(00:01:03) Are Bodybuilders the Edgiest Biohackers?(00:04:51) Strength Training vs. Cardio(00:12:27) Strength Training as a Longevity Tool(00:16:32) Moving Toward Functional Movement(00:21:10) Reframing Movement in Your Mind(00:29:17) Why Veganism Is Dangerous(00:33:27) Do Carbs Make You Fat?(00:38:34) Should You Reverse Diet?(00:40:54) How Much Protein Should You Eat?(00:50:18) Is There Any Good Reason To Eat Chicken?(00:55:10) Winning Carb Choices(00:59:42) Sal’s #1 Recommended Supplement(01:02:00) The Single Biggest Fitness MistakeSponsorsMitosynergy | Get 15% off now at Mitosynergy.com/Dave40 Years of Zen | Upgrade Your Brain in 5 Days by going to 40YearsOfZen.com/DaveResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Mind Pump Podcast: mindpumppodcast.comMind Pump Training Protocols: mindpumpmedia.com/maps-fitness-productsMind Pump Instagram: @mindpumpmediaSal’s Instagram: @mindpumpdistefanoX: @mindpumpsalTikTok: @mindpumpmediaYouTube: @MindPumpShowThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dive into yoga nidra with Tracee Stanley, a renowned teacher and author who unveils the transformative power of rest. Her book, "Radiant Rest," showcases the vital role of recovery in biohacking, advocating for the strength found in stillness. Tracee, with over twenty years of experience and collaborations with icons like Marianne Williamson, is a leader in the realm of deep rest and clarity. Her latest work, "The Luminous Self," deepens this exploration, aligning with our aim to unlock inner power for a fulfilling life. Today, we delve into yoga nidra's science, its profound effects on our brain, and how it connects us to our roots, reshapes habits, and promotes deep healing. Tracee's approach not only offers a pathway to better understanding and caring for ourselves but also redefines our relationship with rest and the world. Her insights are essential for anyone seeking a holistic biohack for body and mind wellness, providing clarity, compassion, and the gift of deep rest.(00:00:40) Accessing Real Rest & Peace With Yoga Nidra(00:12:25) One Free Daily Practice for Better Sleep, Focus & Productivity(00:26:34) Exploring Death Practices & Connecting to Nature(00:42:34) Creating a Legacy of Peace: Passing on Indigenous Traditions & Teachings(00:53:50) Healing a Sleep Deprived World & Confronting the Root Cause of Suffering(01:08:13) Exploring Tracee’s Tools for Connection & HealingSponsorsCalroy | Calroy.com/Dave for an exclusive discountBioptimizers Blood Sugar Breakthrough | Go to BloodSugarBreakthrough.health/Dave and use code “Dave10” for 10% off your order.ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Read: The Luminous Self by Tracee StanleyRead: Radiant Rest by Tracee StanleyWebsite: traceestanley.comInstagram: @tracee_stanleyThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today’s show is a masterclass in improving your skin without going under the knife. I’m excited to welcome back Dr. Rob Whitfield, an Austin-based plastic surgeon who specializes in breast implant removal surgeries and advanced cosmetic procedures. He invented the famous “No-Cut” Facelift, which revolutionized non-surgical facelifts for a more natural appearance. I worked with Rob on a “No-Cut” Facelift, and he removed excess skin from my back after my weight loss. I got to be the guinea pig, and now I’m sharing everything I learned with you. On today's episode, I recount my experience and results with these procedures. Dr. Rob explains what a “No-Cut” Facelift is, plus other non-surgical procedures to tighten fat, remove excess skin, and reduce wrinkles. We talk about radio frequency-assisted lipolysis, SoftWave therapy, Morpheus8, and a whole lot more. Plus, we get into foods that hurt your skin, injectable vs. topical peptides, and biohacking skincare. Basically, it’s everything you need to know for younger, healthier-looking skin. And let’s face it, we all want that. (00:01:58) Dave’s Experience Working With Dr. Rob(00:08:48) What Is a “No-Cut” Facelift?(00:19:10) Shrinking Fat With Radio Frequency Assisted Lipolysis(00:22:13) Zoom Lifts & More Non-Surgical Procedures(00:29:02) What Is SoftWave Therapy?(00:33:28) Biohacking for Skincare(00:34:47) Morpheus8: Good or Bad?(00:35:53) Treatments for Excess Skin(00:37:44) How Bad Are BBLs?(00:41:57) Does Your Skin Have a Biological Clock?(00:45:32) Foods That Hurt Your Skin(00:48:18) Topical vs. Injectable Peptides(00:50:17) The Bright Side of Sun Exposure(00:53:42) What To Do for Your Skin at 25SponsorsLeela Q | Visit LeelaQ.com/Dave for 10% off.Timeline Nutrition | Go to TimelineNutrition.com/Dave and get 10% off your order.ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: drrobertwhitfield.comThe HARP™️ Method: harp.healthInstagram: @breastimplantillnessexpertInstagram: @drrobwhitfieldFacebook: Dr. Rob Whitfield MDYouTube: @breastimplantillnessexpertTikTok: @drrobertwhitfieldHow Breast Implants Compromise Your Health and Make You Sick #1043The Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Inflammation is at the root of everything. More inflammation means less energy and a higher risk of every disease. Today, we’re digging into exactly why inflammation is so insidious with functional medicine nurse practitioner Maggie Berghoff. Maggie is a USA Today National Best-Selling author of the book Eat to Treat: Your Three-Step Plan To Reduce Inflammation, Detoxify Your Life, And Heal Your Body. She is also the founder of wellness supplement and non-toxic home line DETOXDaily. In this episode, we talk all about inflammation—what causes it, how it hurts us, and how to combat it. We explore all the different types of inflammation, including physiological vs. psychological inflammation– and dig into how inflammation intersects with hormone health, thyroid function, and metabolic syndrome. Maggie also shares her perspective about shedding shame around eating, and why perfectionism can be even more toxic than actually toxic foods. Plus, I share a lot of horrifying (but medically useful) information about urine. You’ll be equally intrigued and grossed out. (00:01:29) The Ills of Inflammation(00:07:23) Physiological vs. Psychological Inflammation(00:15:00) 3 Things That Cause Inflammation(00:25:26) Are We More Inflamed Now Than Ever?(00:27:19) Where Do You Start Combating Inflammation?(00:30:09) What Is Your Inflammation Type?(00:35:50) When Your Hormones Are in Havoc(00:46:58) Metabolic Syndrome’s Role in Inflammation(00:49:22) The Nightmare of Poor Sleep(00:55:18) Shedding Shame Around Food(01:02:20) Why Not Just Take Aspirin?SponsorsQuantum Upgrade | Go to QuantumUpgrade.io/dave for a 15 day free trialStemregen | Go to Stemregen.co/dave for 20% offResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: maggieberghoff.comEat To Treat: eattotreat.comDETOX Daily: yourdetoxdaily.comInstagram: @maggie_berghoffFacebook: Maggie Berghoff TikTok: @maggie_berghoff Linkedin: Maggie Berghoff The Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Meet a man who makes miracles happen. Today, I’m joined in the studio by Hal Elrod, author of the international bestseller The Miracle Morning and his newest book, The Miracle Equation. After overcoming multiple near-death experiences and financial hardships, Hal channeled his adversity into helping others overcome their own challenges. His Miracle Morning approach has impacted millions of lives.On today’s episode, Hal tells us all about his updated version of The Miracle Morning. He explains SAVERS, the six foundational practices that will transform your morning and change your life. We also talk about tips for hacking your sleep, productivity, and relationships. Hal shares the stories of his devastating car accident and rare cancer diagnosis—and the superpowers he gained from coming back to life. We explore how these near-death experiences changed his perspective on life and what he values most. He also tackles some tough questions… Should we try to help everyone? What does it mean to be a “man”? And what does it take to truly serve others? There’s so much to take away from Hal’s refreshing and optimistic perspective. (00:03:20) Creative Ways To Hold Yourself Accountable(00:13:57) Ditching Veganism(00:21:08) Hal’s Near-Death Experiences(00:27:35) Taking Your Health in Your Hands(00:29:37) Did Hal Come Back With Superpowers?(00:31:55) Are You Supposed To Help Everyone?(00:40:51) How the Miracle Morning Changed Hal’s LIfe(00:43:42) What Does It Mean To Be a “Man”?(00:51:25) Customizing Your Morning To Meet Your Needs(00:54:05) The Six Savers for Success(00:56:53) Tips To Save Your Sleep(01:01:51) The MVP of Personal Development Practices(01:06:14) Nourishing Our ConnectionsSponsorsViome | Go to Viome.com/Dave and save $110 on the full-body intelligence test. Neurohacker | Go to Neurohacker.com/Dave and try it risk free for up to 100 days. Use code “DAVE” at checkout for 15% now.ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Read: The Miracle Morning and The Miracle EquationWebsite: halelrod.comFacebook: Hal ElrodX: @HalElrodYouTube: @HalElrodThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Imagine the benefits of stem cell regeneration without needles or a high cost. Today, I'm excited to introduce Christian Drapeau, inventor of a groundbreaking plant-based stem cell product for health and longevity.Christian is more than a scientist; he's a stem cell expert and herbalist, pioneering plant-based stem cell enhancers. Yes, plants and stem cells together! His background from McGill University and work at Stemtech International make him a leading voice in stem cell science. His book, 'Cracking the Stem Cell Code,' reveals how our bodies use stem cells for repair, and his latest research shows how aquatic plants can boost stem cell production, like nature's own fountain of youth.We'll explore how Christian's journey in ancient herbalism led to innovative discoveries in stem cell enhancement and clarify the difference between traditional procedures and products like STEMREGEN. Stay tuned for key answers: How do stem cells promote longer, healthier lives? What's the truth about stem cells and cancer? When's the best time to start using these products?I'll also share my personal routine for maximizing stem cell supplement effects. If you're excited about affordable, effective health benefits, try STEMREGEN. Visit stemregen.co/dave to save 20% on your order.(00:01:09) STEMREGEN: Understanding The Herbalism x Stem Cell Crossover(00:12:21) Stem Cells & Longevity 101(00:23:55) The Historical Context of Healing & Longevity with Plants(00:32:05) Affordability & Cancer Prevention with STEMREGEN(00:44:27) Preventing Kidney Stones & Lowering Your pH (00:57:37) Dave’s Biohacking Stack for STEMREGEN Enhancement (01:05:51) Improving Mitochondrial Function & Measuring AgeSponsorsBioptimizers | Go to Bioptimizers.com/dave, and use code "Dave10" for 10% offResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: stemregen.co/daveInstagram: @stemregenYouTube: STEMREGENThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, we’re digging into specifics about food that you haven’t heard on the show before. This one may very well influence you to rethink your “healthy” diet and change how you feel about food completely. To get there, I’m excited to welcome back Teri Cochrane, an integrative practitioner and pioneer in personalized healthcare. Teri is the founder of the Global Sustainable Health Institute® and developer of The Cochrane Method®, a future-facing algorithm for decoding the human body. Teri is also one of the world’s leading experts on dietary amyloids, which is a topic I love talking about.In today’s episode, we get into what amyloids are and how they turn on viruses, cause cancer, and shorten our lives. We also explore the dangers of oxalates and histamines, plus hacks to reduce and release them. Teri and I both have our own recipes for releasing oxalates that you can try at home (they’re surprisingly simple). We talk about how dirty poultry is killing us—and how superfoods like kale and almonds aren’t any better. We break down the benefits of regenerative farming, and share ways to make your dollar stretch if you can’t afford grass-fed meat. Plus, Teri tells us what she personally eats. (00:02:01) The Big 4 Metabolic Impairments(00:08:21) The Dangers of Oxalates(00:12:02) The Fifth Disruptor: Histamine(00:16:22) Becoming Your Own Body Interpreter(00:28:41) How Do We Get Off Oxalates?(00:35:41) Dave’s Recipe for Releasing Oxalates(00:44:40) Hacks for Histamines(00:50:32) Amyloid 101: What You Should Know(00:56:56) Should You Beware of B6?(00:59:54) What’s the Best Kind of Protein?SponsorsCalroy Arterosil & Vascanox Bundle | Head over to calroy.com/dave for an exclusive discount.ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: tericochrane.comInstagram: @tericochranebeyondnutritionYouTube: @TeriCochraneThe Global Sustainable Health Institute: globalsustainablehealthinstitute.comRead: The Wildatarian Diet by Teri Cochrane What You Eat is Turning Your Genes On and Off – Teri Cochrane – #646The Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Meet the man who’s making leaps forward in functional movement training. Ben Patrick (aka the Knees Over Toes Guy) went from chronic knee issues to becoming a dunking sensation with his remarkable 42-inch vertical leap. His journey led him to discover the unconventional “knees over toes” method. He now trains to reverse joint pain and defy aging.In this episode, Ben shares his three game-changing foundations of exercise. We look back at the history of backward walking, and talk about its benefits today. Ben gives us his best tips for strengthening and healing knees, calves, shins, hip flexors, and shoulders. We start from the ground up with fixes for feet and toes. Plus, we talk about the problem with most shoes.Today’s biggest takeaway is recognizing the connection between functional movement and longevity. Functional training is key to how long you live and how well you live. Whether you’re 18 and want to do parkour or you’re 80 and want to get up off the floor—or still do parkour—you’ll want to hear this one. (00:04:45) What’s Up With Knees Over Toes?(00:13:58) Strengthening Joints, Not Just Muscles(00:19:54) Starting Off on the Right Foot(00:28:21) Taking It Back to Basics(00:38:30) Will These Workouts Help or Hurt Your Joints?(00:45:09) Fixes From the Toes Up(00:53:48) How To Have Healthy Hip Flexors(01:00:33) Healthy Movement Patterns for Life(01:03:03:) Secrets To Shoulder Healing(01:05:50) Marketing That Actually Helps PeopleSponsorsQuantum Upgrade | Go to QuantumUpgrade.io/Dave for a 7-day free trialResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: atgonlinecoaching.comATG Equipment: atgequipment.comInstagram: @kneesovertoesguyYouTube: @TheKneesovertoesguy TikTok: @kneesovertoesguyBiohacking Conference: biohackingconference.comThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, we're learning how to Biohack like a Woman. And trust me, it's not about counting calories or giving up your favorite foods; it's a whole new paradigm. I'm thrilled to introduce you to our incredible guest today, someone I've had the privilege of working with for several years—Aggie Lal aka Biohacking Bestie. Aggie is not your average biohacker; she's a public figure, bestselling author, health coach and a TEDx Speaker. She's been featured on TV and started the renowned Travel her Shoes blog over a decade ago, eventually leading her down the path of biohacking after realizing the toll constant travel can take on your health.Aggie's journey has led her to establish the Higher Self Academy, where she offers courses to help individuals, especially women, personalize their biohacking journeys. She's also the host of the Biohacking Bestie podcast—make sure to check out our recent conversation on her show. I love the work Aggie’s doing so much, that I even wrote the foreword for her groundbreaking new book, Biohack Like a Woman, which is all about revolutionizing weight loss and biohacking specifically tailored for women.In today's episode, we delve into topics like fertility, understanding perimenopause, and exploring distinct biohacking recommendations for men and women. Aggie and I discuss why women must honor their cycle when trying new practices and the common challenges women face when under-eating calories and exercising. Plus, Aggie shares her valuable nutritional advice for women, including protein intake per meal. (00:02:01) Aggie’s Mission To Empower Women Through Biohacking(00:10:46) Addressing Stress Response Capacity & The Importance of Rest & Recovery(00:21:12) Biohacking Your Cycle, Fertility & Birth Control(00:34:55) Nourishing Women: Understanding the Impact of Caloric Deficiency & Exercise(00:44:53) Embracing New Relationship Dynamics & Women’s Innate Power(00:54:24) How Biohacking Is Disrupting Mainstream Medicine(00:59:21) Nutritional Recommendations for WomenSponsorsBiOptimizers Magnesium Breakthrough | Go to bioptimizers.com/dave for 10% off your order.ARMRA | Try it out for yourself at tryarmra.com. Use code DAVE to get 15% off your first order.ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Read: Biohack Like a Woman Biohacking Bestie: biohackingbestie.comHigher Self Academy: higherselfacademy.coInstagram: @aggieInstagram: @biohackingbestieYouTube: @biohackingbestieTikTok: @biohackingbestieBiohacking Bestie Podcast: biohackingbestie.com/pages/biohacking-bestie-podcastThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today’s very special episode comes from inside Kimbal Musk’s kitchen, where I get a hands-on look at his passion for cooking, community, and regenerative farming. Kimbal Musk is a South African restaurateur, chef, entrepreneur and a board member at Tesla Inc. and SpaceX, companies led by his brother, Elon Musk. Outside of the tech space, Kimbal is the force behind The Kitchen Restaurant Group and co-founder and chairman of Big Green, where he's pioneering outdoor classroom Learning Gardens in schools nationwide. Additionally, Kimbal co-founded Square Roots, an innovative urban farming venture utilizing hydroponic, climate-controlled shipping containers. In our last interview at his newly opened restaurant, The Kitchen, we explored the intersection of technology, regenerative agriculture, and grass-fed cuisine. Today, we unpack Kimbal's passion for food and community. Seriously, we’re not just chatting about technology and longevity here—Kimbal teaches me how best to prepare, serve, and enjoy grass fed steak to perfection. During this live tutorial, we talk about how the energy you put into preparing your food really does impact how it tastes, and his unique perspective on innovation and leadership, gained from working closely with his brother Elon and the teams at Tesla and SpaceX. Then, we explore the highlights of his new cookbook, The Kitchen Cookbook: Cooking for Your Community, a treasure trove of real-food recipes accompanied by easy to follow video tutorials. It’s an incredibly valuable resource for anyone that’s interested in bringing more realness to their food prep and diet.(00:02:14) Embracing Community Through Food(00:18:33) Teaching Kids About Regenerative Farming With Big Green(00:28:56) Try the Kitchen Cookbook for Better Family Meals(00:38:52) Kimbal Musk on Psychedelics: In or Out?(00:43:06) Cooking for Elon Musk(00:47:27) Learn How To Prep & Cook a Beautiful Grass-Fed Steak Live(00:59:22) Kitchen Thoughts on Longevity & Death(01:04:12) Exploring the Link Between Quality Fats & TestosteroneSponsorsApollo Neuro Wearable | Head to apolloneuro.com to save 15% on your Apollo wearable.CAROL Bike | Save $250 on CAROL Bike until January 15th with code DAVE at carolbike.com.ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Organic Revolution: Kimbal Musk’s Mission to Take Down Big Food # 504Big Green: biggreen.org Read: The Kitchen Cookbook by Kimbal MuskThe Kitchen: thekitchen.comRead: Elon Musk by Walter IsaacsonThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today’s guest is not a scientist but a true visionary. Gary Vaynerchuk (aka Gary Vee), is a self-made entrepreneur and digital marketing pioneer. He started his business journey with a lemonade stand at age seven. Now, he’s a prolific content creator, best-selling author, and the co-founder of the massive digital agency VaynerMedia. What I love about Gary is that he leads with integrity, optimism, and, above all, gratitude. He’s a guy of wisdom, not just business—and that’s an important element of what The Human Upgrade is all about.In today’s episode, we explore how entrepreneurship has changed since Gary and I started. We get into how to grow a business in 2024 and Gary’s advice for anyone starting out. His secret to success will surprise you. We talk a lot about gratitude, and how that lens has shaped Gary’s long career and kept him from burning out. Gary also shares his perspective on today’s social media landscape, the importance of kind candor, and why we should look to our elders. No doubt, listening to Gary will inspire you to go after your passions and try that thing you’ve been putting off. In Gary’s words, your happiness is worth fighting for!(00:02:01) Redefining Success as an Entrepreneur(00:07:02) How Gary’s Upbringing Impacted His Success(00:10:32) The Truth About Social Media in 2024(00:14:49) Is Everyone Just Copying Each Other?(00:18:50) Gratitude As the Antidote for Burnout(00:24:11) Championing Wisdom Instead of Youth(00:29:21) Prioritizing Joy Over Riches(00:38:02) Recognizing the Importance of Kind Candor(00:43:08) Reframing Relationships & the Perspectives You Engage With(00:47:17) Leading With Gratitude, Not FearSponsor40 Years of Zen | Go to 40yearsofzen.com/dave to receive an exclusive offer for podcast listeners. ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: garyvaynerchuk.comInstagram: @garyveeTikTok: @garyveeFacebook: Gary Vaynerchuk YouTube: @garyveeX: @garyveeDiscord: VeeFriends The Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

I'm excited to welcome back Dr. Steven Gundry to The Human Upgrade for his sixth appearance, a tribute to his remarkable insights and ongoing research.Dr. Gundry, a true pioneer, is renowned for his books like "The Plant Paradox" and his groundbreaking work on lectins, changing how we understand our body's reaction to food. He's also a top cardiothoracic surgeon and a leader in robotic cardiac surgery, with over two decades of research into the microbiome, using diet and nutrition as key treatment tools. His book, "Unlocking the Keto Code," and his wellness line, GundryMD, have made significant impacts in health and nutrition.In this episode, we dive into cutting-edge research from his new book “Gut Check.” Dr. Gundry discusses the microbiome's connection to disease, and gut health's role in hormone regulation, crucial for mental health during menopause. He'll also share insights on dietary choices, the truth about parasites, and nicotine's unexpected role in longevity.Dr. Gundry's transformative wisdom bridges traditional and alternative medicine. A big thank you to him for another enlightening visit. Thanks for joining us on this journey of discovery!(00:00:22) The Latest Research on How To Reverse Disease(00:10:16) The Link Between Leaky Gut & Gluten(00:16:50) Debunking Blue Zones(00:19:28) What Meat Products You Should Eat & Avoid(00:23:43) The Latest Data on New 5GC, 5AC & Fermented Meat(00:34:27) The Real Issue with Oxalates & How To Boost Your Defenses(00:41:33) How the Microbiome Influences Hormones & Menopause(00:48:10) What Foods Have the Highest Risk for Parasites According to Dr. Gundry(00:55:11) Benefits & Risks of Berberine(00:58:21) The Surprising Truth About Nicotine & Longevity(01:09:11) The Downside to Too Much Olive OilSponsorsARMRA | Visit tryarmra.com and use the code DAVE to get 15% off your first order.Leela Q | Visit leelaq.com/dave and get a 10% discount on LeelaQ products. ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Read: Gut Check by Dr. Steven GundryWebsite: drgundry.comPodcast: The Dr. Gundry PodcastKeto Gets an Upgrade – Dr. Steven Gundry #912How to Identify Your Energy Blockers and Beat Fatigue – Dr. Steven Gundry with Dave Asprey – #803 How Foods are Harming Your Kids – Steven Gundry, M.D. – #649Healthy Aging Begins and Ends in the Gut – Dr. Steven Gundry #604How Nutrition Can Reverse Disease and the Impact of Lectins – Dr. Steven Gundry – #417The Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

On today’s Upgrade Spotlight episode, we’re talking all about NAD+. In the biohacking world, everyone and their mother has heard of NMN and NAD+, but there’s more to it than meets the eye. To get into the nitty gritty of NAD+, we’re joined by Dr. Gregory Kelly, a naturopathic physician and the lead product formulator at Neurohacker Collective, also known as Qualia. I’m an advisor to the company, and they do fantastic and innovative work in the longevity space. Their NAD+ supplement is a quantum leap in biohacking and a no-brainer to add to your stack. In today’s episode, Dr. Kelly explains what NAD is and why it’s essential for longevity, cognition, energy levels, and athletic performance. We talk about the differences between NR, NMN, and Niacinamide. We also explore the most efficient way to get NAD. Is an IV worth the money or will supplements give you more bang for your buck? Plus, Dr. Kelly breaks down exactly what’s included—and not included—in the Qualia NAD+ formula. I’ve been a major proponent of NAD for more than 10 years, but I don’t like to spend all my time and money getting it. If you feel the same, you’re going to want to tune into this episode. (00:01:55) What Is NAD & Why Do We Care?(00:06:19) The Most Efficient Way To Get NAD(00:09:55) Sirtuin’s Superpowers (00:14:42) The Qualia NAD+ Formula (00:22:37) The Buzz on Coffee Berry (00:25:53) When Is the Best Time To Take NAD+? (00:30:01) NAD+ in Clinical Trials (00:34:16) What’s NOT in the Qualia Supplement (00:38:02) A Quantum Leap for Biohacking Episode SponsorNeurohacker | Boost YOUR NAD+ up to 50%* + GET 50% OFF  go to neurohacker.com/DAVENAD.ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Visit neurohacker.com/davenad to save 50% on Qualia NAD+ by Neurohacker Neurohacker Collective: neurohacker.comNeurohacker Collective Instagram: @neurohacker Linkedin: Gregory Kelly The Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, we take a look into the mindset and habits of successful entrepreneurs and mastering the art of organization for success, topics that today’s guest has totally mastered. Jesse Itzler has an impressive background with a bachelor's degree from American University and a further degree in justice, law, and society. His resume as an entrepreneur is also quite impressive, co-founding Marquis Jet, the world's largest private jet card company, which was later sold to Berkshire Hathaway/NetJets. Beyond this, he's partnered with Zico coconut water, selling it to The Coca-Cola Company, and has ventured into the music industry, co-writing Billboard Top 100 hits and co-founding Alphabet City Sports Records. Jesse is also an acclaimed triathlete and author, with his book, Living with a Seal, becoming a New York Times bestseller.As we step into the early days of 2024, this episode is all about providing you with clear, direct methods to upgrade your life across various facets—work, fitness, and personal development. Tune in as I compare and contrast my organizational methods with Jesse's, the goal being to introduce you to strategies that resonate with you and align with your personality. You'll gain insights into how Jesse efficiently prioritizes his calendar and the skills needed to outperform competition when you’re starting out in business. We also explore habits and tools for staying physically and mentally young, our favorite biohacks, my personal excitement in the field of longevity, and ways to structure your life for maximum return on investment, both in terms of monetary success and happiness. While our methods differ in some areas, our objective is the same: to live a life with minimal regrets, whether you reach 80 or 180 years old. Join us as we discuss the habits of successful entrepreneurs—both from our experience and learning from others at the top of their game—and discover practical ways to implement these lessons into your life.(00:00:20) The Secret to Jesse’s Success in Business & Triathlons(00:05:10) How Jesse Organizes His Life & Implements New Habits(00:22:49) Structuring Support Systems & Early Hires(00:32:41) Lessons From Living With a Seal & Monks(00:48:19) What Biohacks Dave Is Most Excited About(00:54:21) How To Organize Your Time Efficiently(01:01:54) The Mindset & Habits of Successful Entrepreneurs(01:10:34) The Recipe for a Fulfilling Life(01:18:46) Dave’s Top Tools for LongevitySponsor: https://www.viome.com/dave to save $150 full body intelligence test.ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: jesseitzler.comInstagram: @jesseitzlerTikTok: @jesseitzlerYouTube: Jesse ItzlerLinkedin: Jesse ItzlerThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr. Anthony Youn, aka “America’s Holistic Plastic Surgeon,” is an expert in your face. He joins us to answer some burning questions… Can plastic surgery actually be holistic? Can you turn back the clock without going under the knife? And… What work should I get done to my face? Today, we’re talking all about how to hack your face and save your skin. Dr. Youn is a nationally-recognized, board-certified plastic surgeon. He’s the most followed plastic surgeon on social media and a TikTok star. He’s the author of The Age Fix, In Stitches, and Playing God. His new book, Younger For Life, is a complete holistic guide to anti-aging using a process he coined called Autojuvenation. In today’s episode, we get into what Autojuvenation is, and how it helps you look younger without surgery—a surgeon who wants to help you avoid surgery! We talk about blending biohacking and cosmetics, natural vs. medical-grade skincare, collagen peptides, treating hair loss, and whether sunscreen causes or prevents cancer. Dr. Youn also tells us the dumbest things that both men and women do to their faces—and how to avoid them. Let’s face it, many of us want to look younger. This conversation is a fascinating look at how to approach aesthetics from a biohacker’s perspective. (00:01:55) Is There Such Thing As Holistic Plastic Surgery?(00:05:12) Natural vs. Medical-Grade Skincare(00:09:36) Holistic Alternatives That Traditional Physicians Don’t Know(00:16:47) Does Topical Collagen Work?(00:19:45) What Cosmetic Work Should Dave Have Done?(00:25:20) Blending Biohacking & Cosmetics(00:30:38) The Dumbest Things Men Do to Their Skin(00:35:37) Is Sunscreen Preventing or Causing Cancer?(00:38:33) The Dumbest Things Women Do to Their Skin(00:43:54) The Hair-Raising Effects of Hair Loss(00:52:35) Additional Skin Biohacks from a ProSponsors:Tru Kava https://trukava.com/ use code Dave15One Skin: https://www.oneskin.co/ use code Upgrade15ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: dryoun.comPre-order: Younger For Life (over $100 value of free bonuses)TikTok: @doctoryoun Instagram: @tonyyounmdYouTube: @DoctorYounPodcast: The Holistic Plastic Surgery Show  The Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Get ready for this important download on a fascinating biohacking compound you haven’t heard me talk about before: Urolithin A. It’s a postbiotic that supports the mitochondria, and it’s backed by impressive studies on longevity, anti-cancer effects, cognitive function, and muscle strength. In fact, this compound has earned a place in my permanent stack—which you know isn’t easy to pull off.Today, I chat with Dr. Dominic Denk, who’s done some of the original research on Urolithin A and the company that makes it, Timeline Nutrition powered by Mitopure. Dr. Denk works as a physician in the Department of Internal Medicine at University Hospital Frankfurt. Dr. Denk breaks down what Urolithin A is and how it impacts aging and cancer prevention—answering questions on when, how, and why to take Mitopure—before we delve into the powers of mitochondria, how to have more energy production in your cells, and the relationship between energy production and cancer. We also talk T cells, autoimmunity, and inflammation. Plus, we get into the differences in healthcare and pharmaceutical overreach in the U.S. and Germany. Tune in to uncover the latest life-changing compound—and find out what it will do for your heaviest lift in the gym, your cognition before your next big meeting, and to reverse aging over time. (00:03:31) Understanding Urolithin A (00:08:43) Genetic vs. Mitochondrial Cancer (00:14:48) Getting to the Root of Autoimmunity (00:21:19) Strong Evidence on Muscle Strength (00:23:59) Does Cancer Hate Americans? (00:27:59) Why Do We Age? (00:31:35) The Best Studied Compound You’re Not Taking (00:33:02) Talking T Cells (00:36:22) Healthcare in Germany vs. The U.S. (00:43:31) Urolithin A & Hot/Cold Therapies (00:45:55) Tripling Down on mTOR (00:52:05) Are There Downsides to Urolithin A? ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Timeline Nutrition: timelinenutrition.com and use code DAVE to save 10%. After January 1st, 2024, TimelineNutrition.com/dave for 30% discount.Mitopure: mitopure.comX: @DomDenkMDLinkedin: Dr.med. Dominic Denk The Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this special end-of-year "best of" episode, you'll learn the Top 10 hallmarks of aging, the role of functional medicine in restoring and reversing aging, and the many practical ways you can promote your own longevity.Mark Hyman, M.D., joins Dave in Austin to talk all things longevity. Driven by his desire for a healthier, longer life for himself and others, Dr. Mark immersed himself in the latest scientific research on aging and longevity. Through his findings, he realized that the body has an incredible built-in healing system that can be activated through understanding the emerging science of longevity. He also managed to reduce his biological age by 20 years effectively.He consistently tackles the topic of inflammation and its impact on aging—or “Inflammaging” as he calls it. “The body only has so many ways to say ouch,” Dr. Mark says. “You have pain. You have inflammation. You have certain things that happen that create all these symptoms, but there're these common roots. So, inflammation is this common root that seems to accelerate as we get older. So, we can measure biomarkers of inflammation that are highly predictive of mortality.”This conversation covers many components of aging, like metabolic flexibility and resilience, mTor, meat- and plant-based protein, nutrition, environmental allergies and food sensitivities, histamine, autophagy, fasting, DEXA scans, and much more!In his book, "Young Forever: The Secrets to Living Your Longest, Healthiest Life,” Dr. Mark:shares the knowledge of how to unlock the causes of accelerated aging and treat it as a reversible disease.gives you practical tips for daily habits that will increase your energy and performance.teaches you why you age and what it really takes to live a longer, more vibrant life.Watch this episode on YouTube! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade you’ll meet Robert Waldinger, M.D., who leads an extraordinary scientific study on happiness that’s still going strong after eight decades. The study set out to understand human health by what made people thrive.Since 1938, the Harvard Study of Adult Development has tracked two groups of men and their families with the goal of discovering what really makes for a good life. Along the way, thousands of questions were asked, and hundreds of measurements were taken—from brain scans to blood work. Three strong themes emerged from the study: Social connections are really good for you. Loneliness kills.It’s the quality of your close relationships that matters.Good close relationships don’t just protect your body, they protect your brain.Dr. Waldinger combined those lifelong case studies with modern psychological research in his new book, co-authored with Marc Schulz, Ph.D., “The Good Life: Lessons from the World's Longest Scientific Study of Happiness." This discussion gives you real-life tools to hack your happiness. You’ll learn things like:how relationships improve your physical, mental and emotional health. (More than you know!)how to evaluate the effect of your relationships on your well-being. (Don’t be dragged down.)what social fitness is and how to practice it. (Yes, it’s a flex.)ways to enliven and energize your relationships. (Energy totally matters.)why casual and work relationships matter more than you think. (A surprisingly big contribution.)Watch this episode on YouTube!Don’t Miss This! Dr. Waldinger’s TEDtalk about the study is one of TED’s Top 10 episodes and viewed more than 43 million times.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This episode is a deep dive into the heart of modern fitness, led by one of its most influential figures. Joining me today is Lavinia Errico, the visionary co-founder of Equinox Fitness Clubs. Lavinia isn't just a pioneer in the fitness industry, she's a passionate advocate for a life that's healthier, more fulfilled, balanced, and brimming with joy. She's dedicated to helping others achieve these same goals, inspiring people to delve into self-awareness and embrace transformative journeys. With her belief in enjoying the journey and embracing the process, Lavinia has shaped not just her own life but the lives of countless others towards seeing, feeling, and living remarkable results.Today, you’ll hear about how Lavinia's career in fitness and biohacking began with the birth of the modern fitness movement and Equinox as she shares challenges and triumphs of starting a fitness revolution in 1980s New York. You’ll also learn about the unique ethos that set Equinox apart and how building a business with family shaped its upward trajectory.This conversation is threaded with insight into the life of an entrepreneur, the realities of being a CEO, and how Lavinia intuitively balanced her professional journey with motherhood. Lastly, you’ll get a taste of Lavinia's wellness rituals, her philosophy as a lifelong learner, and her exciting new chapter with MOVEJOY, aimed at creating a more stress-free, joyous workout experience for everyone. (00:01:41) Laying the Foundation of Equinox(00:10:44) Finding the Joy of Movement(00:18:56) Advice for Women in Business(00:24:51) The Honest Cost of Being an Entrepreneur & CEO(00:32:14) Wellness Rituals & Being a Student of Life(00:44:47) Introducing Move Joy(00:55:27) Shifting the Why Behind MovementResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: movejoy.lifeInstagram: @laviniajoyLinkedIn: Lavinia ErricoThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today is a long-awaited show with none other than Bryan Johnson, an entrepreneur, venture capitalist, author, and professional rejuvenation athlete on a mission to discover the next evolution of humankind. While Bryan is well known in the longevity space, I’ve been a fan of his work for years because of his neuroscience background. Bryan started a company called Kernel, which makes devices that monitor and record brain activity. Kernel uses what I would call the most comprehensive way of looking at the human brain ever. He is the founder of OS Fund and Braintree, and he spearheads Project Blueprint, an anti-aging experiment where he’s spent multiple years and millions of dollars developing an algorithm to live longer. In today’s wide-ranging talk, we discuss the future of optimizing our brains with AI—delving into all things biohacking and longevity while exploring complicated questions like… Can you die of loneliness? And… Are your critics making you old?Plus, we talk testosterone—an often triggering topic, but an essential conversation. Bryan shares his perspective on why he would rather be respected by people in the 25th century than understood now. Stick around for his surprising takes on olive oil, body hair, and saunas. (00:59) Biohacking The Brain (05:34) Are Your Critics Making You Old?(12:52) What Makes Bryan Tick(20:09) The Longevity-Loneliness Connection (28:27) Accounting For Bio Individuality in Health Protocols (39:09) Does Having a Partner Help You Live Longer? (47:59) Olive Oil vs. Saturated Fats (54:39) Talking Testosterone (01:07:52) Expanding Consciousness with Psychedelics (01:12:06) Questions from the Live Audience Sponsor: Try Qualia NAD+ with an extra 15% off with code Dave15.Resources:Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: protocol.bryanjohnson.comKernel: kernel.comRead: Don’t Die by Zero Instagram: @bryanjohnson_ YouTube: Bryan Johnson Linkedin: Bryan Johnson The Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Coming to you live from Austin, Texas, I can’t wait for you to meet Dan Freed—a man who’s journeyed from the hot kitchen of high-end cooking to the frontier of brain improvement. Dan’s the founder and CEO of Thesis, a company that's revolutionizing the way we think about our brain's potential, and his journey is one of resilience and innovation. Picture this… A kid struggling with focus throughout childhood, he drops out of high school and claws his way up in the ruthless restaurant industry to become a saucier in a three-star Michelin kitchen. But the real twist comes when Dan, grappling with burnout, stumbles upon cognitive performance supplements. This discovery didn't just change his mental game, it transformed his entire life. Fast forward through degrees from Yale and INSEAD, and you have the Dan that sits down for this interview—committed to helping others harness their brainpower to the fullest.We get into the nitty gritty of nootropics and the supplement industry, talking about how Dan's fight with burnout and learning challenges led to the birth of Thesis Nootropics. We share tips on adapting human biology to our modern world, discuss the thorny issues of regulation and quality in the supplement industry, and explain how Thesis uses a unique combined approach of customizing nootropics and expert support for their customers. We round it all off with a look at the remarkable, results-driven formulas that Thesis offers, and how focus is the key to unlocking our greatest potential. Dan's story is a living proof that sometimes, a couple of stumbles can lead to an incredible leap forward, thanks to some conscious action. That’s the kind of journey we all can learn something from.(00:02:14) How Burnout & Learning Challenges Inspired Thesis Nootropics(00:19:15) Is Using Nootropics Cheating?(00:25:37) Tips for Adapting Human Biology to the Modern World(00:32:33) How Thesis Is Customizing Nootropics(00:40:59) Tips for Supporting Your Body’s Homeostasis While Taking a Stimulant(00:46:33) Dave Rings the Alarm on Formulating With Vitamin B6(00:50:53) Regulation & Quality Concerns in the Supplement Industry(00:57:41) Key Ingredients in Thesis’ Clarity & Logic Formulas That Drive Real Results(01:04:28) Unlocking Your Potential Through the Power of FocusResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: takethesis.com and use code “Asprey” for a 10% off all Thesis products.Instagram: @takethesisFacebook: Take ThesisThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Cynthia Thurlow joins the show to talk about how intermittent fasting can help women change their body, metabolic system and brain function. She has tips for women at all stages: from active menstrual cycles to perimenopause to menopause.Cynthia is a Johns Hopkins-trained nurse practitioner and functional nutritionist founded and serves as CEO of Everyday Wellness Project. She holds a Master of Science degree in Nursing and Functional Nutrition certifications with advanced trainings in Endocrinology and Gastroenterology. Her career in healthcare includes nearly 20 years of emergency medicine and cardiology experience. She brings a broad perspective when working with women to improve the state of their health. “I really start from a foundational level talking to women about fasting,” Cynthia says. “It's really honoring our own unique physiology. It's leaning into that menstrual cycle. It's leaning into the lifestyle piece that so much of us forget to talk about with our patients, our sleep quality, stress management, anti-inflammatory nutrition, our exercise quality, our connection with nature, all of which are critically important.”She also addresses diet dogma that frustratingly persists, even with established and emerging science about the benefits of intermittent fasting.She tackles this outdated dogma (and a lot more!) in her new book, “Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.”“[Intermittent fasting] restores our intrinsic rhythms, burns fat, regenerates our health right down to the cellular level, and stabilizes our hormones,” Cynthia says in her book. “In turn, we are less likely to develop obesity, diabetes, vascular diseases, and autoimmune disorders.”At the end of this conversation, you’ll have the tools to decide if intermittent fasting is the right choice for the state of your own health.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dive into a captivating exploration of human biology and connection—erotic blueprints. Discover four primal drivers: fear, food, friends, and fertility, with a unique focus on fertility in this episode.Miss Jaiya, a leader in somatic sexology, sheds light on the intimate realm of human relationships and pleasure. As an award-winning somatic sexologist and creator of The Erotic Blueprints® Framework, Jaiya dedicates her expertise to helping people understand their unique erotic blueprints and their impact on intimate lives. Her latest book, "Your Blueprint for Pleasure," offers invaluable insights into a revolutionary language for bedroom communication and sexual vitality.This episode delves into the concept of erotic blueprints, Jaiya's research, and the unique paths to turn-on and blissful gratification for each individual. This conversation aims to understand people's true desires and needs in intimate relationships, free from taboos or judgment.Highlighting that sex and intimacy are vital for well-being, just like food and breathing, this discussion includes personal experiences and emphasizes the importance of vulnerability. Learn how understanding your erotic blueprint can enhance connections and satisfaction in the bedroom.Whether seeking to enrich intimate life or deepen understanding of human biology and connection, this episode offers valuable insights for everyone.(01:34) Reconciling Spirituality & Sexuality: Jaiya’s Sexual Empowerment Journey(12:00) Why Sex Is the New Frontier of Personal Growth & Biohacking(15:25) Jaiya’s Wildest Energetically Erotic Experience(21:35) Conscious Kink & Blending Psychedelics With Sexuality(30:52) Your Pleasure Blueprint: Defining the 5 Erotic Types(34:55) Discovering the Erotic Blueprint Through Her Own Relationship(40:01) Addressing the Intimacy Issue in Our World & Sending Love Through the Field(46:44) Confronting the Taboo of Pleasure(52:11) Mastering Energetic Sexuality & Orgasms(01:01:48) Risks in Using Psychedelics for Creation Energy(01:06:49) The Dark Side of Spiritual Ecstatic Altered States & How To Protect Your FieldResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: blueprintbreakthrough.comRead: Your Blueprint For Pleasure by Jaiya Instagram: @missjaiyaThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

I am excited to chat with a longtime friend who is a fellow expert in how to make your brain work better. Jim Kwik is an absolute wizard when it comes to maximizing your brain's potential. We go way back, over a decade, and I can vouch for his incredible expertise in the realm of cognitive enhancement. He also has just released an expanded addition to his best-selling book, Limitless, where he delves deep into topics that both he and I hold near and dear—nootropics and brain enhancement. Jim Kwik is a widely recognized world expert in memory improvement, brain function, and accelerated learning. After a childhood brain injury left him learning-challenged, Kwik created strategies to dramatically enhance his mental performance. He has since dedicated his life to helping others unleash their true genius. In addition to being an author, he serves as ultra-informed host of the top education training podcast: Kwik Brain. His mission: No brain left behind.From overcoming childhood adversity and turning it into a superpower, to the secrets behind better memory and accelerated learning, this episode is full of tools for enhancing cognitive function. Plus, we explore the groundbreaking concepts Jim covers in Limitless: Expanded, including the use of nootropics to elevate brain function, his favorite daily biohacking techniques and brain exercises, and how identifying your brain animal can enhance your self awareness and therefore potential. (00:01:44) Jim Kwik’s Inspiring Brain Health Journey(00:10:18) Top 5 Most Recommended Nootropics(00:16:49) Supplements for Brain Health & Longevity(00:23:32) Jim’s Biohacking Must-Haves & Daily Routine(00:29:53) Healing the Emotional Thread & Embracing Post-Traumatic Growth(00:36:03) Top Exercises for Your Brain(00:47:41) C.O.D.E. – Understanding Your Brain Animal (Cognitive Type)(00:55:57) Leveraging Self-Awareness as a SuperpowerResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: jimkwik.comRead: Limitless Expanded by Jim KwikPodcast: Kwik BrainInstagram: @jimkwikYouTube: Jim KwikLinkedIn: Jim KwikThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today’s guest is nothing short of a modern-day Willy Wonka for Generation X. He built a billion-dollar ecstasy business in the '90s and did not end up behind bars. That's a story you've got to hear. Our guest today, Shaahin Cheyene, not only dabbled in the wild world of herbal ecstasy but also managed to stay out of trouble despite being investigated by seven attorney generals. And get this, he wasn't even 18 when he pulled off these daring feats.Shaahin's story doesn't stop there. Since those days, he's become an Amazon expert, successfully selling nootropics and a variety of other products on the platform. He's also a filmmaker and author of the book, “Billion: How I Became the King of the Thrill Pill Cult.” From Fleeing Iran at the age of five to being homeless and living out of his car, Shaahin's journey is nothing short of remarkable. It's safe to say he's one of the most interesting individuals I've had the pleasure of interviewing. We dive into Shaahin's captivating journey, exploring his transformation from a young criminal to a thriving entrepreneur. You’ll also learn about what went into his groundbreaking herbal ecstasy formula and how he managed to get his business off the ground. Along the way, we discuss the challenges of navigating the bureaucracy of big government, the importance of seeking help when needed, and the valuable lessons Shaahin learned from building and eventually exiting his herbal ecstasy empire. We also delve into how he managed to run a nine-figure company selling on Amazon, the mindset benefits of Brazilian jiu-jitsu training, the power of curating ideas, and how you can strategically leverage podcasts as an entrepreneur. Join us on a ride you won't want to miss.(01:47) How Shaahin Became the King of the Thrill Pill Cult(07:36) Formulating Herbal Ecstasy & Building a Million-Dollar Business(16:34) Navigating the Bureaucracy of Big Government(28:04) Pro Tip for Entrepreneurs: Why It’s Important To Ask for Help(32:09) What Cheyene Learned From Building & Exiting His Business(37:29) What To Do When You Make Your First Million(39:21) Scaling a 9-Figure Company Selling on Amazon(45:05) Lessons From Martial Arts & Our Bets on Musk vs Zuckerberg(54:03) The Tactical Advantage of Podcasting & Being a Curator of Ideas(01:03:30) Media Training 101ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: shaahincheyenne.comPodcastCola: podcastcola.comInstagram: @shaahincheyenePodcast: Business Story of the WeekLinkedIn: Shaahin CheyeneThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

I’ve been eagerly looking forward to this conversation with a dear friend and a true luminary in the realm of relationships and personal development, John Gray. for quite some time. You probably recognize his name as the author of the famous book, Men Are From Mars, Women Are From Venus. But what's especially exciting is how John has evolved his insights to address the changing dynamics between men and women in the modern world, as he highlighted in his 2020 book, Beyond Mars and Venus: Relationship Skills for Today's Complex World.Now, why is this episode a must-listen? Well, John isn't just a relationship expert; he's also a seasoned biohacker who understands the profound impact of our environment – including relationships – on our hormones, happiness, and dopamine levels. In essence, he's been biohacking before it even had a name. With decades of wisdom, he offers invaluable insights into navigating the complexities of male-female relationships in today's world.Delve into the fundamental differences between men and women, the importance of appreciation in relationships, what truly motivates men, and practical tips on boosting testosterone and managing emotions. We also explore how men and women process feelings differently, the art of setting boundaries, and the language of love as the language of hormones.Get ready for a masterclass in understanding the dynamics of modern relationships and how to create lasting happiness.(00:59) Understanding Fundamental Differences Between Men & Women(04:38) Do Men Exist To Make Women Happy?(06:32) Exploring What Drives & Motivates Men(11:09) How To Boost Testosterone & Navigate Emotions(19:14) Why Men Disconnect When Talking About Feelings(30:22) How Men Can Help Women Come Back Into Balance(39:17) Setting Boundaries & Working on Your Relationship(49:41) Advice for Women for How To Talk About Their Feelings With Their Partner(01:02:22) Why the Language of Love Is the Language of Hormones(01:05:48) What Women Need in a Relationship(01:13:07) The Defense Against Attacks on Your Reputation(01:17:49) Techniques for Processing Emotions(01:25:32) Thoughts on Estrogen Receptor Degraders(01:31:48) What Masturbation Does to Men vs. Women(01:37:42) Advice for Couples Not Having SexResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: marsvenus.comRead: Beyond Venus and Mars by John GrayInstagram: @johngraymarsvenus_officialLinkedIn: linkedin.com/in/marsvenusThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today's episode delves deeper into the captivating world of quantum field therapy and the power of intention, featuring the renowned Lynne McTaggart. Lynne, known for her books "The Power of Eight," and “The Field” offers groundbreaking insights into the profound impact of group intention.The discussion unravels the significance of the number 8, explores the mechanics behind Lynne's intention experiments, and examines the profound effects of healing and connection on our being. The conversation extends to the transformative power of expanding connection beyond the individual, the latest scientific developments supporting Lynne's theories, and the exciting potential of new technologies in quantum healing.The episode covers the role of intention in healing polarized communities and intriguing phenomena, such as The Simpsons' seemingly magical foresight.Get ready for a thought-provoking journey with Lynne McTaggart that promises to expand horizons, challenge beliefs, and inspire exploration into the uncharted territories of consciousness and intention.(03:01) What Is Quantum Field Therapy?(06:47) The Power of Eight(16:23) Inside the Power of Eight Experiments(19:40) How Healing & Connection Bring About States of Oneness(30:12) What Happens When You Expand the Group Beyond Eight(34:29) Evolving Our Understanding With the Latest Science(41:30) How New Modalities Support Lynne’s Findings(49:21) Lynne’s Measurement of Success: Stories of Real World Impact(56:44) Joining a Power of Eight Group or Intention Experiment(01:01:45) Healing Polarized Communities Using Altruistic Intention(01:09:14) What Technologies Can Push Boundaries Further?(01:16:15) How Did The Simpsons Magically Predict the Future?ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: lynnemctaggart.comRead: The Power of Eight by Lynne McTaggartYouTube: Lynne McTaggartInstagram: @lynnemctaggartofficialThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

How about we have a conversation with one of the most spiritually influential living people on earth? Yes, you heard that right! Today's guest was bestowed with this honor by Watkins MindBodySpirit, and if that's not impressive enough, AgeNation awarded him a Life Achievement Award. Today, we have the incredible privilege of sitting down with a true luminary in the world of spirituality, health, and resilience. His name is Mark Nepo, and he's not just an authority on spiritual matters and poetry; he's a living testament to the power of the human spirit.Mark is no stranger to adversity; he's a cancer survivor who has weathered life's storms and authored dozens of books, including The Book of Awakening and Surviving Storms: Finding the Strength to Meet Adversity. In essence, he's a true badass in resilience, and we're here to delve into the fusion of science, health, and spirituality with a master of all these realms.Mark's new book, Falling Down and Getting Up: Discovering Your Inner Resilience and Strength, is a profound exploration of how we can navigate life's challenges with acceptance and resilience. Throughout our conversation, we'll touch on the transformative impact of Mark's battle with cancer, the wisdom he's gleaned from our elders, the profound insights from indigenous healing traditions, and the incredible power of building resilience through pain. So, fasten your seatbelts, dear listeners, because this is a conversation that promises to touch your soul and leave you with valuable nuggets of wisdom for your own journey.(02:11) The Spiritual Impact of Overcoming Cancer in His Early 30s(10:05) How Our Beliefs Influence Our Reality(21:14) Navigating the Choice Between Love & Fear(27:11) The Invaluable Impact of Our Teachers & Healers(37:14) How To Face Failure & Build Resilience(47:44) Navigating the Deeper Teachers of Fear, Pain & Grief(01:01:36) Unlock Your Inner WisdomResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: marknepo.comRead: Falling Down and Getting Up by Mark NepoInstagram: @mark_nepoYouTube: Mark NepoFacebook: @MarkNepoOprah’s Review: oprah.comThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, we delve deep into the world of cybernetics and the potential cyberpunk future with a true pioneer and a living legend in the field, Kevin Warwick. As an Emeritus professor at Coventry and Reading Universities, Kevin is celebrated as the world's first cyborg, earning him the moniker: Captain Cyborg.In this episode, we explore the incredible journey of Kevin Warwick, who became a cyborg over 25 years ago by implanting a chip in his arm, the size of a coin, enabling him to interact with the digital world in ways that were once unimaginable. But this isn't just about becoming a cyborg; it's about the potential, the risks, and the opportunities at the intersection of AI, robotics, and biomedical engineering. In doing so, we discuss the fascinating implications of merging humans with technology and how it can reshape our understanding of reality.Kevin's fearless exploration into the world of cybernetics is truly pioneering. He has been willing to take risks to expand our knowledge and possibilities as humans. Join us as we explore the profound implications of merging biology with technology, opening up new realms of human potential and perception, and what our future could hold as technology and research continues to progress. (00:01:43) The Realities of Pioneering Human Enhancement(00:10:05) Kevin’s Implantation Experiment & Research(00:18:10) Expanding Our Biological “Software”(00:24:39) How Far Is Too Far? Risk Tolerance for the Sake of Science(00:32:47) Exploring Human Enhancement Possibilities(00:39:21) Kevin’s Take on Longevity From His Brain Cell Research(00:43:13) Biohacking as an Entry Level Point Into Cyborgs(00:52:41) The Future of Cyborgs, Humans & Artificial IntelligenceResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Podcast: Futures Podcast Read: I, Cyborg by Kevin Warwick Read: Artificial Intelligence: The Basics by Kevin Warwick Linkedin: Kevin Warwick The Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, we talk about one of my favorite biohacking topics: hormones. Starting way back before I first had kids, I’ve studied hormones as they relate to fertility – leading to the first of just a few books over the years, The Better Baby Book. And it's been an area of passion ever since because hormones also control your mood and your energy levels and your happiness.So I wanted to invite Dr. Francesca LeBlanc on the show – someone who has a very interesting blend of being a board certified chiropractor, a doctor of natural medicine, and a clinical nutritionist – to take us through the winding roads of food, lifestyle, and hormones in women. You could call this functional medicine, but Dr. Francesca LeBlanc has a unique spin on it. For years in her 20s and 30s, she suffered from brain fog, mood swings, irregular cycles, insomnia, depression, and anxiety. She spun her wheels with the allopathic model before discovering that the root cause of her symptoms could be traced back to hormone imbalances. Now, Dr. LeBlanc helps patients understand that it’s not all in their heads, and that they can live normal, symptom-free, joyful lives.In this conversation, we dive into her holistic healing journey, and how pioneers in the health biohacking space – including myself – guided and inspired her to create the hormone hierarchy; linking hormones to other chemicals in the brain. We explore what diet and lifestyle changes to make that can significantly improve not only how you feel but how your body functions, identify common deficiencies and inhibitors to healthy hormones, and share tools for stress management.(02:25) Painful Early Steps on Her Journey to Wellness(06:51) Basics of Hormones & Pregnancy(11:39) How Mold & Environmental Toxins Damage Hormones(21:03) Foods That Keep Your Hormones Healthy(27:06) The Hormone Hierarchy(34:44) Most Common Metals Impacting Women’s Hormones(40:33) Tools for Stress Management(48:03) Exploring Various Gateways to Holistic Health Hacking(58:32) Addressing Mineral DeficienciesResourcesSponsor: Go to www.DrinkLMNT.com/Dave and receive a free Sample Pack with your purchase.Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Instagram: @drfrancescaleblancWebsite: labwellhealthcare.comThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, let's delve into a topic often overlooked but crucial for our overall health: our skin. Over the past decade, I've started seeing our skin as more than just a protective layer; it's a major organ, just like our liver or heart. Its health goes beyond appearances – it profoundly influences our biology and well-being.Today, I welcome Carolina Reis Oliveira, the founder of OneSkin, a skin health company, to the show. She'll share exciting insights from recent research on specific peptides that can transform your skin's appearance and functionality.Here's the intriguing part: your skin's health closely links to your body's overall health. Inflamed or unhealthy skin signals underlying issues within your system. Conversely, improving your skin's health can reduce systemic inflammation and positively impact your organs. This revelation led me to discover a groundbreaking peptide called OS-01, found using advanced AI and novel compound-searching techniques.Carolina will explain how peptide OS-01 can reverse your skin’s biological age, the differences in their body, face, and eye formulas, the benefits of their mineral sunscreen to combat skin damage and reduce inflammation, and their new method to measure skin age.If you're considering investing in longevity, this episode is a game-changer. By tackling skin inflammation, you're not only enhancing your appearance but also reducing systemic inflammation, a double win.(00:02:30) Discovering OS-01 & How the Peptide Tackles Skin Aging(00:16:45) Inside the Different OneSkin Formulas for Face & Eyes(00:21:46) Boost the Effects of OS-01 Face With the OneSkin Cleanser(00:24:26) How & Where To Use the Body Lotion for Optimal Results(00:28:02) Exploring Potential OS-01 Systemic Effects(00:34:46) Finding the Right Dose With the OneSkin Formula(00:38:28) Benefits & Use Recommendations for Mineral Based Sunscreen(00:42:27) How OneSkin Activates Collagen & Hyaluronic Acid Production(00:44:43) The MolClock: Discovering a New Way To Measure Skin AgingResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: oneskin.co (use code upgrade15 for 15% off)Instagram: @oneskin.coThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade my guest fits right into the podcast transition to The Human Upgrade because he gets into the grittiness of what humans can do to level themselves up. No. 1 New York Times bestselling author Robert Greene shares science-backed knowledge about human nature.You know you want to be more powerful, more in control and excellent at what you do.Robert’s insights help you do just that. He gives you actionable tips that help you unlock limitations you may be putting on yourself so you can move your life upward and forward. (Similar to something I like to tell my team is great momentum: “up and to the right.”) World leaders, military generals, business executives, philosophers, and hip-hop moguls alike revere Robert’s books.After writing about mastery and power for more than two decades, he’s now become a TikTok sensation and the universal truth for a new generation. He’s one of my favorite authors who’s profoundly influenced my own life and been on the podcast twice before. Both episodes are must listens: The 48 Laws of Power – #380 and The Laws of Human Nature – #575. I asked him back to talk about his latest book: “The Daily Laws: 366 Meditations on Power, Seduction, Mastery, Strategy, and Human Nature.” “In “The 48 Laws of Power,” I talk about deception and con artists,” Robert says. “But in The Laws of Human Nature, it's almost about self-deception, how we're con artists with ourselves, how we create an image of ourselves as being morally right, being a good person, being intelligent, being rational, being empathetic. Whereas in fact, we're usually quite far below that ideal. … Because your default position is to always look externally and blame other people.”In “The Daily Laws,” he distills the best of his previous books and never-before-published material in to one amazing life guide for you. He lays out themes for each month of the year: Power, seduction, persuasion, strategy, human nature, toxic people, self-control, mastery, psychology, leadership, adversity and creativity. Within these themes he features a “daily law” for you to follow.“By not looking at ourselves in an honest way, and glossing over our own flaws and weaknesses, we become trapped in patterns of behavior that we cannot control,” Robert says in his new book. “As the years go by, and the misreadings, missteps, and unrealistic decisions pile up, we can become bitter confused, and damaged.”“The Daily Laws” is designed to reverse [these] toxic patterns and reconnect you to reality,” Robert says. “It takes aim at the various delusions we have all absorbed and seeks to attune your mind instead to the most entrenched traits of human nature and how our brains actually operate.”Listen on for the truth bombs.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Let’s explore the mind-bending subject of quantum biology with Dr. Catherine Clinton, a licensed naturopathic physician with a focus on gut health, autoimmunity and psychoneuroimmunology. A respected author, speaker, health advocate, Dr. Clinton has been on the front lines of health and wellness for over 15 years, helping people overcome the very health challenges I once grappled with in my younger years – issues like autoimmune conditions and Lyme disease, which we now understand are often intertwined with mold toxicity.What makes Dr. Clinton’s journey so intriguing is that she not only healed herself but has also guided countless patients on their paths to recovery. Today, we dive into a profoundly fascinating and complex topic Dr. Clinton knows a lot about, but which is still relatively misunderstood among the public: quantum biology. At a high level, it's all about understanding how our health is intricately connected to the world around us, the flow of electrons, protons, photons of light, and even the vibrations of sound within our biological systems. Think biohacking under a mega microscope.We explore the scientific meaning of the word “quantum,” theories surrounding the origins of consciousness, the incredible role of fascia in the quantum highway of our bodies, the impact of polyphenols and melanin, the incredible new discoveries around structured water, and a whole lot more.Plus, we delve into the emerging field of sound frequency research and even touch on Dr. Clinton's new Quantum Sound Masterclass. I appreciate Dr. Clinton’s work at the cutting edge of quantum biology, and look forward to how these discoveries push the biohacking movement forward.(00:05:47) Understanding Quantum Biology: Where Biology Meets Consciousness(00:13:21) Exploring the Origins of Consciousness (00:18:55) A New Study Proving We Are Quantum Beings (00:24:39) What’s Happening In the Quantum Highway of Fascia Throughout the Body(00:30:49) The Function of Polyphenols & Melanin(00:38:11) What Structured Water Does in the Body(00:46:05) Dr. Clinton’s Masterclass on Quantum Sound & Water Consciousness (00:55:16) Sound Frequency: The Next Biohacking Frontier ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: drcatherineclinton.comQuantum Sound Masterclass: drcatherineclinton.com/quantum-sound-masterclassInstagram: @dr.catherineclintonYouTube: Dr. Catherine Clinton NDFacebook: @dr.catherineclintonndThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Remember the days when we believed in one-size-fits-all diets? Well, thankfully those days are behind us. Today's episode is all about the crucial shift towards personalized nutrition.Our guests, Matt Gallant and Wade Lightheart from BiOptimizers, are no strangers to the show. They're also the authors of The Ultimate Nutrition Bible, a monumental resource that unlocks the secrets of crafting a diet tailored precisely to your genetics, goals, and lifestyle. We delve into the art and science of creating your perfect nutrition plan, exploring the intricate web of genetics, gut health, and lifestyle, and how they all intertwine to shape your dietary needs. Imagine a diet designed exclusively for you, based on your unique genetic makeup and aspirations. It's a paradigm shift for sure; we're here to guide you through it using the latest scientific studies and findings from our personal experiences with biohacking.In this episode, we uncover the importance of aligning your diet with your lifestyle, debate the calories-in vs. calories-out method of losing weight, and share practical insights for how to measure your progress from The Ultimate Nutrition Bible. Plus, we dispel the myth that excessive cardio is the fastest way to lose body fat, and explore the pivotal role of hormones and metabolism for sustainable, safe weight loss.(00:21) Introducing the Ultimate Nutrition Bible: There’s No Evil Foods(10:54) Why Raw Food & Ketogenic Diets Are Not for Everybody(19:30) The Consequences of a Performance Diet & Starvation Survival Mechanisms(33:32) Exploring the Calories-In, Calories-Out Method for Weight Loss(41:05) Understanding Metabolic Adaptation: Why Excessive Cardio Prevents Fat Loss(46:08) How High Quality Sleep Can Aid Weight Loss(51:33) The Simplest Secret for Tracking Your Progress(56:32) Breaking Down Calories vs. Macros in the Ketogenic Diet(01:00:53) Identifying Hormone Issues Based on Weight Distribution(01:05:22) Taking Risks to Achieve Optimal ResultsResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books The Ultimate Nutrition Bible: ultimatenutritionsystem.com/daveWebsite: bioptimizers.comInstagram: @bioptimizersYouTube: BiOptimizersBlog: bioptimizers.com/blogPodcast: Awesome Health PodcastThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

About ten years ago, I began working colostrum into my product development efforts – seeing its game changing nutritional value for exactly what it was, well before the mainstream sank its teeth into it. Today’s guest has the experience and intellect to take us deep into the science behind it.Dr. Sarah Rahal, MD – the brainchild of ARMRA – is a double board-certified pediatric neurologist with expertise in environmental and functional medicine. After years of clinical work and research, she was alarmed by the rise of chronic diseases in young patients due to modern environmental factors like pollutants, pesticides, and more. This led her to leave traditional medicine and develop ARMRA's technology with a mission to minimize the modern environmental impact on human health – a truly honorable and trailblazing path that she explains for us today, from early personal health issues to the future of her fascinating company.More than anything though, this episode serves as the ultimate Colostrum 101 course for anyone interested in learning more, living healthier, and even for those still harboring doubts over things like fasting and ethical sourcing. Dr. Sarah Rahal answers it all and more.(02:59) Dr. Rahal on the State of Children’s Health(05:50) Disillusionment & Leaving the Healthcare System (08:14) Intro to the Formula Industry & Colostrum(12:44) Dr. Rahal’s Near-Death Experience(17:35) Massive Issues in the Dairy Industry  (21:27) ARMRA’s Unique Formulation (28:25) Dave Asprey vs. The World (31:33) Collagen or Colostrum? (38:33) Ethical Sourcing of ARMRA Colostrum(42:27) Diet Combinations for Colostrum (44:24) How Colostrum Supports a Healthy Microbiome(54:34) Considering Colostrum as a Food Product ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Visit tryARMRA.com/Dave for 15% off your first orderInstagram: @tryarmraThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Friends, it is my great pleasure to introduce Vani Hari, aka Food Babe, someone I've had the privilege of knowing for nearly a decade. She is a relentless advocate for clean, safe, and wholesome food. She has dedicated herself to a tireless campaign aimed at eliminating harmful ingredients from our food supply, particularly in the United States, where food standards can sometimes be shockingly low. Her efforts have been resolute in challenging major food corporations when their practices are detrimental to the well-being of our children and society as a whole. Vani Hari's mission is driven by a genuine concern for the greater good, and I dare say that she has had a more significant impact on food safety and quality than some of the regulatory agencies tasked with these responsibilities in the first place. Vani’s new book, Food Baby Family: More Than 100 Recipes and Foolproof Strategies to Help Your Kids Fall in Love with Real Food serves as a comprehensive guide for how her family navigates the challenges of living in a world filled with overly processed, unhealthy food options. In this conversation we discuss the importance of educating your kids on processed foods and proper nutrition early on. Vani and I share some of the lessons we’ve learned in teaching our kids about nutrition, and how we’ve empowered them to choose foods that make them feel good.Together, we have the power to stand up against the multibillion-dollar conglomerates that persist in feeding us products that are, in essence, poison. By making informed, healthier choices for ourselves and our families, we can redirect our resources toward companies that are genuinely committed to improving the landscape and producing high-quality products.(00:03:10) Vani Hari's Journey in Food Activism & ResilienceHow Vani unveiled hidden chemicals in our foodExposing a harmful chemical in Subway bread Read: Feeding You Lies By Vani HariBeing targeted by organized oppositionHow Vani’s health journey inspired her to find purposeNavigating constant badgering online being paid for by big chemical companies How Gabby Bernstein helped Vani persevere through manipulations and attacksThe history of PR in the USWhat drives Vani to continue this workRead: Food Babe Family By Vani Hari (00:24:16) The Truth About Processed Foods & How to Uphold Your Food Values SociallyHow the food industry thrives on making food that isn’t good for our health Removing processed foods from your dietThe importance of educating kids about processed foods early on Teaching kids to be kind and acceptingCommunicating why you do/don’t buy certain foods to your kidsWhat happened when I took my daughters to McDonald’s for the first time How fast food hijacks your brainExposing chemicals in the infamous Pumpkin Spice LatteHow to uphold your food values in social settingsWhy goldfish are banned in Vani’s house and alternative snacks(00:40:41) Helping Kids Navigate Their Food Choices to Make Healthier DecisionsHealthy, satiating breakfast ideas for kidsTruvani collagen: shop.truvani.com/pages/collagen-peptidesWhy Kellogg is one of the most evil companies in the worldEmpowering kids to choose how they feel through the food they eatHow processed foods led to Vani’s appendicitisBeing a happier parent by being less of a perfectionistHow kids can hold you accountableResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Read: Food Babe Family By Vani Hari Website: foodbabe.comYouTube: youtube.com/thefoodbabeInstagram: @thefoodbabeShop: truvani.comThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode, we're broadcasting live from Toronto with Dr. Adeel Khan, a leading figure in the field of gene and cell therapies. Dr. Adeel Khan, who holds an M.D. and is a Canadian Board Certified Physician, specializes in regenerative and cellular medicine. He is also a recognized authority as a key opinion leader for The American College of Regenerative Medicine, the foremost advocate for best practices in North America. Notably, he co-founded Xalt, a fitness-technology company, and played a pivotal role in the development of their proprietary technologies. Additionally, he serves as the Chief Scientific Officer for Science & Humans, a virtual hormonal health company. Dr. Khan's expertise extends globally, as he has treated world champion athletes, members of Royal Families, and celebrities in both Dubai and North America.Personally, I'm thrilled to share that I've recently undergone gene therapy for the very first time in my life. This is a significant moment for me because I've been envisioning the potential of this technology in the context of longevity for the past two decades. In fact, I documented my beliefs about the ability to manipulate stem cells to reverse their aging process in my book, Superhuman. The gene therapy I received, which we'll delve into shortly, was administered via a simple injection. Over the next three to six months, it's expected to reduce my biological age, or intrinsic age, by an impressive seven to nine years—a monumental outcome from just one treatment.Throughout this episode, we'll explore various aspects of stem cell research, particularly the historical use of umbilical cells, which may hold some surprising revelations for you. We'll also discuss the challenges in translating cutting-edge medical research into practical clinical applications and the incredible potential of gene and cell therapy in addressing chronic pain, cancer, and other medical conditions. What's particularly exciting is Dr. Khan's multifaceted approach to biology, working on multiple fronts to harness its potential. This innovative approach offers a glimpse into a promising future, and I couldn't be more thrilled to dive into this conversation.(01:36) Exploring the Impact of Technological Advances & Gene Therapy in Regenerative Medicine• Pure Muscle: puremuscleandfitness.com• Unite Mind & Body to Achieve Health & Healing – Dr. Andrew Weil – #656• How technological advances have impacted the world of regenerative medicine• Learn more: daveasprey.com/genetherapy• Keeping up with the rapid development of medical science• What is plasmid gene therapy? • The history of gene therapy research and accepting the risk of innovation• The attitude towards innovation in other parts of the world• We Can Slow Down Aging Right Now – David Sinclair, Ph.D. – #626• How phellostatin relates to aging (20:42) Revolutionary & Innovative Approaches to Health & Longevity• Democratizing health for everyone with gene therapy • Benefits of intranasal insulin• How industry cross-pollination encourages lateral thinking • Read: Ego Is The Enemy by Ryan Holiday• Explaining the limitations of umbilical cord stem cells and how they’re being optimized• Using gene editing technology to create specific stem cell lines • Using stem cell technology for hair and the reproductive system• The ability for breast enlargement with stem cells (42:47) Stem Cell & Gene Therapy Applications for Cancer & Chronic Pain• The opportunity for chronic disease healing with stem cell therapy• Using CAR T for cancer treatment • Target gene therapies to fix irregular pathways• Ways to improve mitochondrial efficiency• How bad actors could misuse this technology• The correlation between Tesla’s story and gene cell therapy• Big Pharma and government’s role in the suppression of revolutionary medical technology• Using this technology to build resilience in the body to combat modern stressors(01:10:08) Making Revolutionary Medical Advances More Accessible• The logistics of receiving gene cell therapy: how long they last and how they’re given• Improving the immune system through a microbiome upgrade with FMT• The difference between probiotics and FMT• Stem cell and gene therapy treatments for cardiovascular disease• The regulatory fight for your right to have control of your own biology• The problem with institutionalized medical doctors• Treating chronic pain and recognizing the chronic pain burden ResourcesGene Therapy: daveasprey.com/genetherapyDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: eterna.healthInstagram: @dr.akhanYouTube: Doctor AdeelThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, we cover something that everybody wants at some level or another—muscle. If you want to live a long time and you've fallen for the plant based nonsense science that's out there to sell more Froot Loops, well, you're heading in the wrong direction from a longevity perspective. The cold, hard truth is that skeletal muscle mass drives longevity.Dr. Gabrielle Lyon joins the show today to flex her own intellectual muscles on protein intake, reframing the hallmarks of aging, supplementing aminos, healthy fascia, and a whole lot more. You've heard her talk about these things online probably as much as I have; she calls what she does Muscle Centric Medicine—and as you can imagine, I am fully on board. She's looking at aging in exciting new ways in her new book, Forever Strong, which is packed with science-based strategies for aging well.We respectfully lock horns on a few subjects near and dear to our hearts—ranging into symptomatology vs. muscle health, key flaws in modern skeletal muscle research, where to draw the line on veganism, unlocking longevity through diet, and more—before landing on our shared responsibility to the greater community to share these insights for the common good.Dr. Gabrielle Lyon is a true heavyweight in the space and my dear friend, backing up her immense aptitude with real life results as a biohacker seemingly aging at a slower pace than one might expect. It’s a pleasure to welcome her to the show today.(02:38) Correlation Between Aging & Skeletal Muscle Mass • Read: Forever Strong by Dr. Gabrielle Lyon• Dr. Gabrielle’s informed background in geriatric medicine• Modern symptomatology vs. skeletal muscle health• Reframing the hallmarks of aging• 40 Years of Zen• Gaps in modern skeletal muscle measuring • A New Whole-Body MRI Scan Sees Everything - Raj Attariwala M.D., Ph.D. #989• Optimizing genetic potential • Benefits to weight training as a young person • How much weight training is ideal?• Read: The One-Minute Workout by Martin Gibala• Skeletal muscle as body armor (23:30) To Protein or Not to Protein? There’s No Question• Protein intake with regard to longevity• Mythbusting mechanistic target of rapamycin (mTOR)• Kevin Hart ends up in wheelchair after being ‘dumbest man alive’• One possible benefit to animal protein restriction • Considering protein instead as its 20 amino acids • Benefits to collagen supplementation• Read: The Switch by Mr. James W. Clement• Not-So-Science Fiction: Extending Your Healthspan Gets Real - James Clement #608(37:29) Applying the Science: Everyday Tips & Practices• Spacing amino acids throughout the day • Dr. Lyon’s longevity protocol• Eating earlier for circadian alignment• Evidence hedging intermittent fasting • Negative impact of alcohol on aging (47:42) Fascia, Muscle & Hernias: What’s the Connection?• Importance of fascia in aging • Recommendations to avoid hernia surgery• Explaining the tensegrity principle as it relates to muscle health • Value of functional movement practice • Link between the virus and an increase in mast cells (50:26) Best Proteins & Why You Shouldn’t Go Vegan• Dr. Lyon’s recommended animal protein powders  • Why vegan farts are the real problem • Other important bioavailable nutrients in animal protein • Veganism in younger/older people• Wielding the responsibility to educate • Dave’s health journey and inspiration• Supplementing amino acids • Read: Forever Strong by Dr. Gabrielle LyonResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: drgabriellelyon.comRead: Forever Strong by Dr. Gabrielle LyonInstagram: @drgabriellelyonPodcast: The Dr. Gabrielle Lyon ShowYouTube: Dr. Gabrielle LyonFacebook: Doctor Gabrielle LyonX: @drgabriellelyonThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of The Human Upgrade - anesthetist and researcher, Mark Harper, M.D., Ph.D., shares how the power of cold-water practices can treat depression, anxiety, PTSD, arthritis, migraines and other health conditions you may be experiencing.Despite all the attention cold water swimming and immersion has gotten in recent years—thank you, Wim Hof—the scientific community hasn’t taken it very seriously. That’s changing now. Dr. Harper’s research goes beyond what we already know about the benefits of cold-water therapy and lays out best practices for you.In this episode you’ll learn: How to safely establish your own customized practice of cold-water swimmingThe ideal plunge frequency How to heat your body from the inside outWhy using saunas can optimize your plungesThe effects of putting your face in cold water vs. just your bodyWhy swimming “in the wild”—lakes, rivers, seas — benefits you even more How community plays a role in cold plunge practicesAnd moreYou’ll also learn about science and case studies found in Dr. Harper’s book, “Chill: The Cold Water Swim Cure - A Transformative Guide to Renew Your Body and Mind.” He explains how cold water has the ability to impacts us physiologically and mentally.As Dr. Harper shares his long-awaited evidence on cold-water’s therapeutic power to strengthen the immune system, cell regeneration, and everyday vitality, you’ll come to understand how to harness the power of cold-water swimming. If you are looking to up your cold-water therapy game, you’ll get a lot of value from this episode. Dr. Harper says you can start simply, one small movement into cold water at a time: “Your rest, digest, chill out, and anti-inflammatory response comes from putting your face into the water,” he says. He then goes on to other cold-water swim tips.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Every 13 minutes, a woman dies of breast cancer. And this unnecessary epidemic affects men, too. Today, you’ll hear a fascinating interview with a woman on a mission to empower people to do more than just survive breast cancer, but become radiantly healthy; Dr. Toni Galardi. She's not only a holistic psychotherapist with a PhD in psychology, but a remarkable individual who cured herself of breast cancer. Dr. Galardi is a prolific author with three books under her belt, including her latest one titled BreastQuake: 10 Steps to Awakening from Breast Cancer. In this episode, we delve deep into the esoteric realm of breast cancer; discussing alternative methods for treatment, lowering the risk of breast cancer, and exploring groundbreaking studies that shed light on the incredible healing potential of consciousness within the body. You see, it's essential to understand that psychology plays a crucial role in the context of cancer. While psychology doesn't cause cancer, ignoring the mind-body connection in the conversation is a missed opportunity. Our bodies possess a remarkable intelligence, residing within our mitochondria, and a distributed consciousness that affects our well-being. So, even if you don't have breasts or breast cancer isn't on your radar, this conversation offers profound insights into psychology's impact on health and wellness.Dr. Toni Galardi is deeply passionate about helping women navigate their cancer treatment plans, emphasizing the importance of aligning with one's passions, as she believes that passion holds significant healing potential. Throughout this episode, you'll learn about Dr. Galardi’s personal journey with breast cancer, the eye-opening studies she uncovered regarding the high cost of treatment, her recommendations for more affordable (and even free) healing tools, and her unique approach to harmonizing the energetic and emotional aspects of the human experience to combat cancer and reduce your risk. I want to extend my sincere appreciation to Dr. Toni Galardi for her courage in authoring this groundbreaking book and fearlessly addressing topics that some may question. She calls it as she sees it, and that's precisely why her insights are so valuable.(02:27) The Role of Shame & Love in the Cancer Recovery Journey• Read: Cancerpreneur by Mike Koenigs• What Toni decided to do when she got her breast cancer diagnosis• The data around how women really feel about their breasts• Who does and doesn’t have shame around their breasts• How Toni’s shamanic training and somatic experience came into her healing process• The World is Your Petri Dish with Bruce Lipton – #336• The compelling link between shame and breast cancer• Working with consciousness in the body to cure diagnoses• Developing the muscle of dream recall• Intuition is Not a Feeling – Joy Martina – #574• Loving your breasts into cancer remission(19:26) Optimizing Diet, Lifestyle & Emotional Well-being for Breast Cancer Resilience• Diet changes to implement when diagnosed with breast cancer• How to alkaline your diet & limit acidic foods• Should you avoid dairy or soy if you have breast cancer?• Exploring what the cancer personality looks like• Studies of the impact of negative life events on cancer diagnoses• Energetic cleansing and hygiene tips(35:20) Empowering Self-Care & Healing Tools for Breast Cancer Prevention & Recovery• Diagnostic test recommendations to see if you’re at risk• Queen of Thrones castor oil packs • Using thermography• Read: The Power of Eight by Lynn McTaggart• The high cost of breast cancer treatment compared to other cancers• Using the free tool of the power of eight to heal breast cancer • How toxic relationships & childhood trauma play a role in breast cancer• Watch: A Call to Courage with Brene Brown on Netflix• How to deal with trolls on social mediaResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: drtonigalardi.comInstagram:@drtonigalardiLinkedIn: linkedin.com/in/dr-toni-galardi-909a5a7Facebook: facebook.com/drtoniThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In today's episode I’m reuniting with someone who has had a profound impact on my journey as a biohacker, Rollin McCraty, the director of research at the HeartMath Institute. Rollin specializes in the physiology of emotion, and his research explores how emotions impact cognition, behavior, health, and global interconnectivity. I first encountered Rollin nearly two decades ago during my tenure at the Silicon Valley Health Institute. Back then, I was a young enthusiast, navigating the intricate world of anti-aging and longevity, learning from the seasoned wisdom of octogenarians who were defying the natural aging process. Rollin introduced me to the profound connection between cutting-edge science and practices often dismissed back then, like meditation. In a world where admitting to meditating could raise eyebrows and questions about your sanity, Rollin illuminated the scientific links connecting our biology, nervous system, and conscious mind. It was a revelation, a glimpse into the integral role these connections play not just in personal well-being but in the unseen, yet palpable, impact we have on others. Now, as a 50-year-old with the biological markers that defy my calendar age, I attribute part of my own transformation to insights gained from pioneers like Rollin. As a biohacker, personal development isn’t just a journey inward but a meticulous tuning of the body’s ‘hardware’ to optimize function and performance. In this episode we’re uncovering the impact our energetics can have on others and the world around us. We talk about heart rate variability and coherence, and its importance in aging. We discuss the magnetic environment we live in, and the human response to these natural phenomena. We talk about the impact of phones on our biology, how technology can potentially be harnessed to positively affect human consciousness and global coherence, and changing DNA with intention. And if you’re now motivated to dive into coherence training, we give some tools for that. It’s an honor to have Rollin on the show today, a testament to the evolution of biohacking, where the convergence of science and consciousness isn’t just acknowledged but celebrated.(03:39) Unlocking the Power of Heart Rate Variability & Earth’s Natural Rhythms• What heart rate variability is why it’s important for understanding aging• My experience as a HeartMath coach and using a heart rate variability monitor• How we affect each other from our heart rate coherence• Research conducted through the Global Coherence Initiative on fields line resonances• Why it’s beneficial to be in sync with the rhythm of the earth• An overview of the Schumann Resonances(33:37) How the Earth’s Magnetic Environment Impacts Our Biology• The global magnetometer measuring system• How understanding the magnetic environment we live in can help us be more resilient• What disturbed fields can do to humans• How our phones impact our biology• Measuring global consciousness with Global Consciousness Project 2.0• Recognizing and pushing past our own limiting beliefs(46:35) Exploring Coherence Training & Quantum Consciousness for Healing• Using technology to affect consciousness in a positive way• Global Coherence app• How we are becoming aware of what we're feeding the field • Where to start with becoming more aligned and shifting into coherence• The role of mitochondria in coherence training• How you can change your DNA with coherence and intention• Biohacking’s link to epigenetics• The World is Your Petri Dish with Bruce Lipton – #336• Tap into Tapping: The EFT Episode – Dawson Church # 474• Mastering Brain Waves and Creating Mind Bridges – Dawson Church – #653• Channeling healing through energetic fields at Joe Dispenza workshops• Biohacking Conference: biohackingconference.com• Rollin’s work with Joe Dispenza• Quantum level processing and consciousness• Global Coherence Initiative: heartmath.org/GCI• Read: Science of the Heart by Rollin McCraty• Read: Heart IntelligenceResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: heartmath.orgInstagram: @heartmathinstituteGlobal Coherence Initiative: heartmath.org/GCIThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.