S2E4: The Startup Security Playbook: AI That Keeps Up with AI — with Francesco Piccoli (Almanax).
S2E4: The Startup Security Playbook: AI That Keeps Up with AI — with Francesco Piccoli (Almanax).  
Podcast: Startups Decoded
Published On: Mon Oct 06 2025
Description: Send us a textHow LLMs are rewriting application security: less false positives, faster triage, and real-world founder playbooks.Founders are sprinting on AI—attackers are too. Traditional security tools drown teams in alerts and miss the real threats. In this episode, Almanax founder & CEO Francesco Piccoli breaks down AI-native application security: how LLMs detect logic bugs legacy scanners miss, cut up to 90% of noise, and triage vulnerabilities at the pace you ship. We cover where “shift-left” falls short, how to operationalize low-friction code scanning in GitHub, and what legal/compliance leaders expect before they’ll sign your deal.If you’re building or buying AI-accelerated software as a founder, CTO, or security lead, this is the playbook.Chapters00:00 AI-Native Security: Why It Matters Now01:19 Francesco’s Path to AppSec05:26 Why Legacy Tools Miss Real Bugs10:48 The Cat-and-Mouse Reality of Cyber15:46 Legal & Compliance: What Founders Owe20:34 Founder Best Practices (Week-1 Checklist)28:46 Cutting 90% of Alert Noise36:32 Making Security Usable for Devs39:45 When Breaches Happen: First Calls41:53 Wrap-Up + Next StepsFrancesco PiccoliFounder and CEO of Almanax, joins us to unpack how his team is building AI-native systems to catch 5x more bugs while cutting 90% of the noise. We talk about the future of application security, why shift-left isn’t enough anymore, and how triaging vulnerabilities at scale requires a new kind of intelligence.Who Should ListenSeed–Series B founders shipping fast on AI-native stacksEng leaders drowning in SAST/DAST false positivesSecurity & compliance owners prepping for SOC 2 / ISO 27001Music Credit: "Neptuno" - Phondupe (Album: Onykia)Access All Areas.Listen: Apple || Spotify || YouTubeSubscribe: SubstackCommunity & Events: Founders CircleConnect: Need clarity on fundraising, strategy, or scaling? You can book me, Andy Walsh, directly on Hubble for focused 1:1 advice. 15, 30, or 45 minutes no fluff, just solutions.Head to hubble.social/AndyWalshDiscover Smarter Investing with the Teaminvest Wealth Builders PodcastExpert insights and proven strategies from Australia's top investors. Build your wealth.Listen on: Apple Podcasts   SpotifySupport the show